Lymphatic filariasis disseminating to the upper extremity.
Identifieur interne : 001453 ( PubMed/Checkpoint ); précédent : 001452; suivant : 001454Lymphatic filariasis disseminating to the upper extremity.
Auteurs : Catherine Maldjian [États-Unis] ; Vineet Khanna [États-Unis] ; Bevan Tandon [États-Unis] ; Matthew Then [États-Unis] ; Mohamed Yassin [États-Unis] ; Richard Adam [États-Unis] ; Michael J. Klein [États-Unis]Source :
- Case reports in radiology [ 2090-6862 ] ; 2014.
Abstract
Lymphatic filariasis is the most common cause of acquired lymphedema worldwide (Szuba and Rockson, 1998). It is endemic to tropical and subtropical regions, and its effects are devastating. With over 100 million infected persons, it ranks second only to leprosy as the leading cause of permanent and long-term disability. Wuchereria bancrofti is the etiologic agent in 90% of cases. There is a dearth of published MRI findings with pathologically proven active infections, making this entity even more of a diagnostic dilemma. Imaging may provide the first clue that one is dealing with a parasite and may facilitate proper treatment and containment of this disease. This is the first report of pathologic correlation with MRI findings in the extremity in active filariasis. The magnetic resonance images demonstrate an enhancing, infiltrative, mass-like appearance with partial encasement of vasculature that has not been previously described in filariasis. Low signal strands in T2-hyperintense dilated lymphatic channels are seen and may depict live adult worms. We hypothesize that the low signal strands correspond to the collagen rich acellular cuticle. This, in combination with the surrounding hyperintense T2 signal, corresponding to a dilated lymphatic channel, may provide more specific MRI findings for active nematodal infection, which can prompt early biopsy, pathological correlation, and diagnosis.
DOI: 10.1155/2014/985680
PubMed: 24707427
Affiliations:
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Klein</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology and Laboratory Medicine, Hospital for Special Surgery, New York, NY 10021, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, Hospital for Special Surgery, New York, NY 10021</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author></analytic><series><title level="j">Case reports in radiology</title><idno type="ISSN">2090-6862</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Lymphatic filariasis is the most common cause of acquired lymphedema worldwide (Szuba and Rockson, 1998). It is endemic to tropical and subtropical regions, and its effects are devastating. With over 100 million infected persons, it ranks second only to leprosy as the leading cause of permanent and long-term disability. Wuchereria bancrofti is the etiologic agent in 90% of cases. There is a dearth of published MRI findings with pathologically proven active infections, making this entity even more of a diagnostic dilemma. Imaging may provide the first clue that one is dealing with a parasite and may facilitate proper treatment and containment of this disease. This is the first report of pathologic correlation with MRI findings in the extremity in active filariasis. The magnetic resonance images demonstrate an enhancing, infiltrative, mass-like appearance with partial encasement of vasculature that has not been previously described in filariasis. Low signal strands in T2-hyperintense dilated lymphatic channels are seen and may depict live adult worms. We hypothesize that the low signal strands correspond to the collagen rich acellular cuticle. This, in combination with the surrounding hyperintense T2 signal, corresponding to a dilated lymphatic channel, may provide more specific MRI findings for active nematodal infection, which can prompt early biopsy, pathological correlation, and diagnosis.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">24707427</PMID><DateCreated><Year>2014</Year><Month>04</Month><Day>07</Day></DateCreated><DateCompleted><Year>2014</Year><Month>04</Month><Day>07</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">2090-6862</ISSN><JournalIssue CitedMedium="Print"><Volume>2014</Volume><PubDate><Year>2014</Year></PubDate></JournalIssue><Title>Case reports in radiology</Title><ISOAbbreviation>Case Rep Radiol</ISOAbbreviation></Journal><ArticleTitle>Lymphatic filariasis disseminating to the upper extremity.</ArticleTitle><Pagination><MedlinePgn>985680</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1155/2014/985680</ELocationID><Abstract><AbstractText>Lymphatic filariasis is the most common cause of acquired lymphedema worldwide (Szuba and Rockson, 1998). It is endemic to tropical and subtropical regions, and its effects are devastating. With over 100 million infected persons, it ranks second only to leprosy as the leading cause of permanent and long-term disability. Wuchereria bancrofti is the etiologic agent in 90% of cases. There is a dearth of published MRI findings with pathologically proven active infections, making this entity even more of a diagnostic dilemma. Imaging may provide the first clue that one is dealing with a parasite and may facilitate proper treatment and containment of this disease. This is the first report of pathologic correlation with MRI findings in the extremity in active filariasis. The magnetic resonance images demonstrate an enhancing, infiltrative, mass-like appearance with partial encasement of vasculature that has not been previously described in filariasis. Low signal strands in T2-hyperintense dilated lymphatic channels are seen and may depict live adult worms. We hypothesize that the low signal strands correspond to the collagen rich acellular cuticle. This, in combination with the surrounding hyperintense T2 signal, corresponding to a dilated lymphatic channel, may provide more specific MRI findings for active nematodal infection, which can prompt early biopsy, pathological correlation, and diagnosis.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Maldjian</LastName><ForeName>Catherine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khanna</LastName><ForeName>Vineet</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tandon</LastName><ForeName>Bevan</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Then</LastName><ForeName>Matthew</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yassin</LastName><ForeName>Mohamed</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Infectious Diseases, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adam</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Klein</LastName><ForeName>Michael J</ForeName><Initials>MJ</Initials><AffiliationInfo><Affiliation>Department of Pathology and Laboratory Medicine, Hospital for Special Surgery, New York, NY 10021, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>02</Month><Day>19</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Case Rep Radiol</MedlineTA><NlmUniqueID>101580187</NlmUniqueID><ISSNLinking>2090-6870</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Adv Parasitol. 2003;53:85-148</RefSource><PMID Version="1">14587697</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Foot Ankle Int. 1999 Nov;20(11):738-40</RefSource><PMID Version="1">10582851</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AJR Am J Roentgenol. 1993 Apr;160(4):813-7</RefSource><PMID Version="1">8456670</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Vasc Med. 1998;3(2):145-56</RefSource><PMID Version="1">9796078</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur Radiol. 2002 Sep;12(9):2349-51</RefSource><PMID Version="1">12195494</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Invest Radiol. 1992 Apr;27(4):293-7</RefSource><PMID Version="1">1601619</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AJR Am J Roentgenol. 2005 Oct;185(4):1011-4</RefSource><PMID Version="1">16177425</PMID></CommentsCorrections></CommentsCorrectionsList><OtherID Source="NLM">PMC3965918</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>09</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>12</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>4</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>4</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>4</Month><Day>8</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24707427</ArticleId><ArticleId IdType="doi">10.1155/2014/985680</ArticleId><ArticleId IdType="pmc">PMC3965918</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Pennsylvanie</li><li>État de New York</li></region></list><tree><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Maldjian, Catherine" sort="Maldjian, Catherine" uniqKey="Maldjian C" first="Catherine" last="Maldjian">Catherine Maldjian</name></region><name sortKey="Adam, Richard" sort="Adam, Richard" uniqKey="Adam R" first="Richard" last="Adam">Richard Adam</name><name sortKey="Khanna, Vineet" sort="Khanna, Vineet" uniqKey="Khanna V" first="Vineet" last="Khanna">Vineet Khanna</name><name sortKey="Klein, Michael J" sort="Klein, Michael J" uniqKey="Klein M" first="Michael J" last="Klein">Michael J. Klein</name><name sortKey="Tandon, Bevan" sort="Tandon, Bevan" uniqKey="Tandon B" first="Bevan" last="Tandon">Bevan Tandon</name><name sortKey="Then, Matthew" sort="Then, Matthew" uniqKey="Then M" first="Matthew" last="Then">Matthew Then</name><name sortKey="Yassin, Mohamed" sort="Yassin, Mohamed" uniqKey="Yassin M" first="Mohamed" last="Yassin">Mohamed Yassin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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