Human Immunodeficiency Virus, Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi.
Identifieur interne : 000E88 ( PubMed/Checkpoint ); précédent : 000E87; suivant : 000E89Human Immunodeficiency Virus, Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi.
Auteurs : Terence Tafatatha [Royaume-Uni] ; Miriam Taegtmeyer [Royaume-Uni] ; Bagrey Ngwira [Royaume-Uni] ; Amos Phiri [Malawi] ; Mariot Kondowe [Malawi] ; Wilson Piston [Malawi] ; Anna Molesworth [Royaume-Uni] ; Ndoliwe Kayuni [Malawi] ; Olivier Koole [Royaume-Uni] ; Amelia Crampin [Royaume-Uni] ; John Horton [Royaume-Uni] ; Neil French [Royaume-Uni]Source :
- PLoS neglected tropical diseases [ 1935-2735 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Antigènes d'helminthe (sang), Antirétroviraux (usage thérapeutique), Co-infection (épidémiologie), Facteurs temps, Filariose lymphatique (épidémiologie), Humains, Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Malawi (épidémiologie), Population rurale (), Prévalence, Études transversales.
- MESH :
- sang : Antigènes d'helminthe.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Antirétroviraux.
- épidémiologie : Co-infection, Filariose lymphatique, Infections à VIH, Malawi.
- Adulte, Facteurs temps, Humains, Population rurale, Prévalence, Études transversales.
- Wicri :
- geographic : Malawi.
English descriptors
- KwdEn :
- Adult, Anti-Retroviral Agents (therapeutic use), Antigens, Helminth (blood), Coinfection (epidemiology), Cross-Sectional Studies, Elephantiasis, Filarial (epidemiology), HIV Infections (drug therapy), HIV Infections (epidemiology), Humans, Malawi (epidemiology), Prevalence, Rural Population (statistics & numerical data), Time Factors.
- MESH :
- chemical , blood : Antigens, Helminth.
- chemical , therapeutic use : Anti-Retroviral Agents.
- geographic , epidemiology : Malawi.
- drug therapy : HIV Infections.
- epidemiology : Coinfection, Elephantiasis, Filarial, HIV Infections.
- statistics & numerical data : Rural Population.
- Adult, Cross-Sectional Studies, Humans, Prevalence, Time Factors.
Abstract
Lymphatic filariasis (LF) and human immunodeficiency virus (HIV) are major public health problems. Individuals may be co-infected, raising the possibility of important interactions between these two pathogens with consequences for LF elimination through annual mass drug administration (MDA).
DOI: 10.1371/journal.pntd.0003825
PubMed: 26042839
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:26042839Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Human Immunodeficiency Virus, Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi.</title>
<author><name sortKey="Tafatatha, Terence" sort="Tafatatha, Terence" uniqKey="Tafatatha T" first="Terence" last="Tafatatha">Terence Tafatatha</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea>
<wicri:noRegion>Liverpool</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Taegtmeyer, Miriam" sort="Taegtmeyer, Miriam" uniqKey="Taegtmeyer M" first="Miriam" last="Taegtmeyer">Miriam Taegtmeyer</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea>
<wicri:noRegion>Liverpool</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ngwira, Bagrey" sort="Ngwira, Bagrey" uniqKey="Ngwira B" first="Bagrey" last="Ngwira">Bagrey Ngwira</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Phiri, Amos" sort="Phiri, Amos" uniqKey="Phiri A" first="Amos" last="Phiri">Amos Phiri</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kondowe, Mariot" sort="Kondowe, Mariot" uniqKey="Kondowe M" first="Mariot" last="Kondowe">Mariot Kondowe</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Piston, Wilson" sort="Piston, Wilson" uniqKey="Piston W" first="Wilson" last="Piston">Wilson Piston</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Molesworth, Anna" sort="Molesworth, Anna" uniqKey="Molesworth A" first="Anna" last="Molesworth">Anna Molesworth</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kayuni, Ndoliwe" sort="Kayuni, Ndoliwe" uniqKey="Kayuni N" first="Ndoliwe" last="Kayuni">Ndoliwe Kayuni</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Koole, Olivier" sort="Koole, Olivier" uniqKey="Koole O" first="Olivier" last="Koole">Olivier Koole</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Crampin, Amelia" sort="Crampin, Amelia" uniqKey="Crampin A" first="Amelia" last="Crampin">Amelia Crampin</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Horton, John" sort="Horton, John" uniqKey="Horton J" first="John" last="Horton">John Horton</name>
<affiliation wicri:level="1"><nlm:affiliation>Tropical Projects, Hitchin, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Tropical Projects, Hitchin</wicri:regionArea>
<wicri:noRegion>Hitchin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="French, Neil" sort="French, Neil" uniqKey="French N" first="Neil" last="French">Neil French</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; Institute of Infection and Global Health, University of Liverpool, Liverpool</wicri:regionArea>
<wicri:noRegion>Liverpool</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2015">2015</date>
<idno type="RBID">pubmed:26042839</idno>
<idno type="pmid">26042839</idno>
<idno type="doi">10.1371/journal.pntd.0003825</idno>
<idno type="wicri:Area/PubMed/Corpus">000E51</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E51</idno>
<idno type="wicri:Area/PubMed/Curation">000E51</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E51</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000E51</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E51</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Human Immunodeficiency Virus, Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi.</title>
<author><name sortKey="Tafatatha, Terence" sort="Tafatatha, Terence" uniqKey="Tafatatha T" first="Terence" last="Tafatatha">Terence Tafatatha</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea>
<wicri:noRegion>Liverpool</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Taegtmeyer, Miriam" sort="Taegtmeyer, Miriam" uniqKey="Taegtmeyer M" first="Miriam" last="Taegtmeyer">Miriam Taegtmeyer</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea>
<wicri:noRegion>Liverpool</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ngwira, Bagrey" sort="Ngwira, Bagrey" uniqKey="Ngwira B" first="Bagrey" last="Ngwira">Bagrey Ngwira</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Phiri, Amos" sort="Phiri, Amos" uniqKey="Phiri A" first="Amos" last="Phiri">Amos Phiri</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kondowe, Mariot" sort="Kondowe, Mariot" uniqKey="Kondowe M" first="Mariot" last="Kondowe">Mariot Kondowe</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Piston, Wilson" sort="Piston, Wilson" uniqKey="Piston W" first="Wilson" last="Piston">Wilson Piston</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Molesworth, Anna" sort="Molesworth, Anna" uniqKey="Molesworth A" first="Anna" last="Molesworth">Anna Molesworth</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kayuni, Ndoliwe" sort="Kayuni, Ndoliwe" uniqKey="Kayuni N" first="Ndoliwe" last="Kayuni">Ndoliwe Kayuni</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District</wicri:regionArea>
<wicri:noRegion>Karonga District</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Koole, Olivier" sort="Koole, Olivier" uniqKey="Koole O" first="Olivier" last="Koole">Olivier Koole</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Crampin, Amelia" sort="Crampin, Amelia" uniqKey="Crampin A" first="Amelia" last="Crampin">Amelia Crampin</name>
<affiliation wicri:level="3"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Horton, John" sort="Horton, John" uniqKey="Horton J" first="John" last="Horton">John Horton</name>
<affiliation wicri:level="1"><nlm:affiliation>Tropical Projects, Hitchin, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Tropical Projects, Hitchin</wicri:regionArea>
<wicri:noRegion>Hitchin</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="French, Neil" sort="French, Neil" uniqKey="French N" first="Neil" last="French">Neil French</name>
<affiliation wicri:level="1"><nlm:affiliation>Karonga Prevention Study, Karonga District, Malawi; Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Karonga Prevention Study, Karonga District, Malawi; Institute of Infection and Global Health, University of Liverpool, Liverpool</wicri:regionArea>
<wicri:noRegion>Liverpool</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS neglected tropical diseases</title>
<idno type="eISSN">1935-2735</idno>
<imprint><date when="2015" type="published">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Anti-Retroviral Agents (therapeutic use)</term>
<term>Antigens, Helminth (blood)</term>
<term>Coinfection (epidemiology)</term>
<term>Cross-Sectional Studies</term>
<term>Elephantiasis, Filarial (epidemiology)</term>
<term>HIV Infections (drug therapy)</term>
<term>HIV Infections (epidemiology)</term>
<term>Humans</term>
<term>Malawi (epidemiology)</term>
<term>Prevalence</term>
<term>Rural Population (statistics & numerical data)</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Antigènes d'helminthe (sang)</term>
<term>Antirétroviraux (usage thérapeutique)</term>
<term>Co-infection (épidémiologie)</term>
<term>Facteurs temps</term>
<term>Filariose lymphatique (épidémiologie)</term>
<term>Humains</term>
<term>Infections à VIH (traitement médicamenteux)</term>
<term>Infections à VIH (épidémiologie)</term>
<term>Malawi (épidémiologie)</term>
<term>Population rurale ()</term>
<term>Prévalence</term>
<term>Études transversales</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antigens, Helminth</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Retroviral Agents</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Malawi</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coinfection</term>
<term>Elephantiasis, Filarial</term>
<term>HIV Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Antigènes d'helminthe</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Rural Population</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antirétroviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Co-infection</term>
<term>Filariose lymphatique</term>
<term>Infections à VIH</term>
<term>Malawi</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Cross-Sectional Studies</term>
<term>Humans</term>
<term>Prevalence</term>
<term>Time Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Facteurs temps</term>
<term>Humains</term>
<term>Population rurale</term>
<term>Prévalence</term>
<term>Études transversales</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Malawi</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Lymphatic filariasis (LF) and human immunodeficiency virus (HIV) are major public health problems. Individuals may be co-infected, raising the possibility of important interactions between these two pathogens with consequences for LF elimination through annual mass drug administration (MDA).</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26042839</PMID>
<DateCreated><Year>2015</Year>
<Month>06</Month>
<Day>05</Day>
</DateCreated>
<DateCompleted><Year>2016</Year>
<Month>03</Month>
<Day>08</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>02</Month>
<Day>20</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1935-2735</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>9</Volume>
<Issue>6</Issue>
<PubDate><Year>2015</Year>
</PubDate>
</JournalIssue>
<Title>PLoS neglected tropical diseases</Title>
<ISOAbbreviation>PLoS Negl Trop Dis</ISOAbbreviation>
</Journal>
<ArticleTitle>Human Immunodeficiency Virus, Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi.</ArticleTitle>
<Pagination><MedlinePgn>e0003825</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pntd.0003825</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Lymphatic filariasis (LF) and human immunodeficiency virus (HIV) are major public health problems. Individuals may be co-infected, raising the possibility of important interactions between these two pathogens with consequences for LF elimination through annual mass drug administration (MDA).</AbstractText>
<AbstractText Label="METHODOLOGY AND PRINCIPAL FINDINGS" NlmCategory="RESULTS">We analysed circulating filarial antigenaemia (CFA) by HIV infection status among adults in two sites in northern Malawi, a region endemic for both LF and HIV. Stored blood samples and data from two geographically separate studies were used: one a recruitment phase of a clinical trial of anti-filarial agent dosing regimens, and the other a whole population annual HIV sero-survey. In study one, 1,851 consecutive adult volunteers were screened for HIV and LF infection. CFA prevalence was 25.4% (43/169) in HIV-positive and 23.6% (351/1487) in HIV-negative participants (p=0.57). Geometric mean CFA concentrations were 859 and 1660 antigen units per ml of blood (Ag/ml) respectively, geometric mean ratio (GMR) 0.85, 95%CI 0.49-1.50. In 7,863 adults in study two, CFA prevalence was 20.9% (86/411) in HIV-positive and 24.0% (1789/7452) in HIV-negative participants (p=0.15). Geometric mean CFA concentrations were 630 and 839 Ag/ml respectively (GMR 0.75, 95%CI 0.60-0.94). In the HIV-positive group, antiretroviral therapy (ART) use was associated with a lower CFA prevalence, 12.7% (18/142) vs. 25.3% (67/265), (OR 0.43, 95%CI 0.24-0.76). Prevalence of CFA decreased with duration of ART use, 15.2% 0-1 year (n=59), 13.6% >1-2 years (n=44), 10.0% >2-3 years (n=30) and 0% >3-4 years treatment (n=9), p<0.01 χ2 for linear trend.</AbstractText>
<AbstractText Label="CONCLUSIONS/SIGNIFICANCE" NlmCategory="CONCLUSIONS">In this large cross-sectional study of two distinct LF-exposed populations, there is no evidence that HIV infection has an impact on LF epidemiology that will interfere with LF control measures. A significant association of ART use with lower CFA prevalence merits further investigation to understand this apparent beneficial impact of ART.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tafatatha</LastName>
<ForeName>Terence</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi; Centre for Neglected Tropical Diseases, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Taegtmeyer</LastName>
<ForeName>Miriam</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of International Public Health, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ngwira</LastName>
<ForeName>Bagrey</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Phiri</LastName>
<ForeName>Amos</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kondowe</LastName>
<ForeName>Mariot</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Piston</LastName>
<ForeName>Wilson</ForeName>
<Initials>W</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Molesworth</LastName>
<ForeName>Anna</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kayuni</LastName>
<ForeName>Ndoliwe</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Koole</LastName>
<ForeName>Olivier</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Crampin</LastName>
<ForeName>Amelia</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi; London School of Hygiene and Tropical Medicine, London, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Horton</LastName>
<ForeName>John</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Tropical Projects, Hitchin, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>French</LastName>
<ForeName>Neil</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Karonga Prevention Study, Karonga District, Malawi; Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>079828/Z/06/Z</GrantID>
<Agency>Wellcome Trust</Agency>
<Country>United Kingdom</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2015</Year>
<Month>06</Month>
<Day>04</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS Negl Trop Dis</MedlineTA>
<NlmUniqueID>101291488</NlmUniqueID>
<ISSNLinking>1935-2727</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D044966">Anti-Retroviral Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000947">Antigens, Helminth</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Filaria J. 2007 Nov 29;6:12</RefSource>
<PMID Version="1">18047646</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2008 Oct;79(4):558-60</RefSource>
<PMID Version="1">18840744</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 2004 Nov 15;190(10):1869-79</RefSource>
<PMID Version="1">15499545</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Cochrane Database Syst Rev. 2009;(3):CD006419</RefSource>
<PMID Version="1">19588389</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2007 Sep;77(3):507-13</RefSource>
<PMID Version="1">17827369</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int J Epidemiol. 2012 Jun;41(3):676-85</RefSource>
<PMID Version="1">22729235</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int Migr. 1998;36(4):445-68</RefSource>
<PMID Version="1">12295093</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Braz J Infect Dis. 2001 Dec;5(6):339-44</RefSource>
<PMID Version="1">12010598</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>AIDS. 2013 Jan 14;27(2):233-42</RefSource>
<PMID Version="1">22842993</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2006 Jun;100(6):543-50</RefSource>
<PMID Version="1">16324731</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2002 Jun;7(6):479-88</RefSource>
<PMID Version="1">12031069</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2014 Feb;19(2):224-35</RefSource>
<PMID Version="1">24438053</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Natl Med J India. 2002 Sep-Oct;15(5):263-6</RefSource>
<PMID Version="1">12502137</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 1996 Dec;1(6):859-64</RefSource>
<PMID Version="1">8980602</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trop Med Parasitol. 1990 Dec;41(4):403-6</RefSource>
<PMID Version="1">2075384</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Today. 1997 Oct;13(10):401-4</RefSource>
<PMID Version="1">15275155</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2015 Mar;9(3):e0003622</RefSource>
<PMID Version="1">25793933</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Acquir Immune Defic Syndr. 2010 Dec 15;55(5):625-30</RefSource>
<PMID Version="1">21934554</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 2000 Dec;182(6):1804-8</RefSource>
<PMID Version="1">11069260</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2007 Jun;101(6):602-12</RefSource>
<PMID Version="1">17395223</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 2002 Mar;96(2):137-44</RefSource>
<PMID Version="1">12080974</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Natl Med J India. 2004 Nov-Dec;17(6):304-6</RefSource>
<PMID Version="1">15736550</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Asian Pac J Allergy Immunol. 2003 Dec;21(4):253-7</RefSource>
<PMID Version="1">15198343</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2015 Jun;109(6):393-9</RefSource>
<PMID Version="1">25877874</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D044966" MajorTopicYN="N">Anti-Retroviral Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000947" MajorTopicYN="N">Antigens, Helminth</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D060085" MajorTopicYN="N">Coinfection</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008295" MajorTopicYN="N" Type="Geographic">Malawi</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012424" MajorTopicYN="N">Rural Population</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">PMC4456405</OtherID>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year>
<Month>10</Month>
<Day>13</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2015</Year>
<Month>05</Month>
<Day>12</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2015</Year>
<Month>6</Month>
<Day>5</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2015</Year>
<Month>6</Month>
<Day>5</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2016</Year>
<Month>3</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">26042839</ArticleId>
<ArticleId IdType="doi">10.1371/journal.pntd.0003825</ArticleId>
<ArticleId IdType="pii">PNTD-D-14-01803</ArticleId>
<ArticleId IdType="pmc">PMC4456405</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Malawi</li>
<li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Grand Londres</li>
</region>
<settlement><li>Londres</li>
</settlement>
</list>
<tree><country name="Royaume-Uni"><noRegion><name sortKey="Tafatatha, Terence" sort="Tafatatha, Terence" uniqKey="Tafatatha T" first="Terence" last="Tafatatha">Terence Tafatatha</name>
</noRegion>
<name sortKey="Crampin, Amelia" sort="Crampin, Amelia" uniqKey="Crampin A" first="Amelia" last="Crampin">Amelia Crampin</name>
<name sortKey="French, Neil" sort="French, Neil" uniqKey="French N" first="Neil" last="French">Neil French</name>
<name sortKey="Horton, John" sort="Horton, John" uniqKey="Horton J" first="John" last="Horton">John Horton</name>
<name sortKey="Koole, Olivier" sort="Koole, Olivier" uniqKey="Koole O" first="Olivier" last="Koole">Olivier Koole</name>
<name sortKey="Molesworth, Anna" sort="Molesworth, Anna" uniqKey="Molesworth A" first="Anna" last="Molesworth">Anna Molesworth</name>
<name sortKey="Ngwira, Bagrey" sort="Ngwira, Bagrey" uniqKey="Ngwira B" first="Bagrey" last="Ngwira">Bagrey Ngwira</name>
<name sortKey="Taegtmeyer, Miriam" sort="Taegtmeyer, Miriam" uniqKey="Taegtmeyer M" first="Miriam" last="Taegtmeyer">Miriam Taegtmeyer</name>
</country>
<country name="Malawi"><noRegion><name sortKey="Phiri, Amos" sort="Phiri, Amos" uniqKey="Phiri A" first="Amos" last="Phiri">Amos Phiri</name>
</noRegion>
<name sortKey="Kayuni, Ndoliwe" sort="Kayuni, Ndoliwe" uniqKey="Kayuni N" first="Ndoliwe" last="Kayuni">Ndoliwe Kayuni</name>
<name sortKey="Kondowe, Mariot" sort="Kondowe, Mariot" uniqKey="Kondowe M" first="Mariot" last="Kondowe">Mariot Kondowe</name>
<name sortKey="Piston, Wilson" sort="Piston, Wilson" uniqKey="Piston W" first="Wilson" last="Piston">Wilson Piston</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E88 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000E88 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= PubMed |étape= Checkpoint |type= RBID |clé= pubmed:26042839 |texte= Human Immunodeficiency Virus, Antiretroviral Therapy and Markers of Lymphatic Filariasis Infection: A Cross-sectional Study in Rural Northern Malawi. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:26042839" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
![]() | This area was generated with Dilib version V0.6.31. | ![]() |