Lymph node grafting in the treatment of upper limb lymphoedema: a clinical trial.
Identifieur interne : 000E28 ( PubMed/Checkpoint ); précédent : 000E27; suivant : 000E29Lymph node grafting in the treatment of upper limb lymphoedema: a clinical trial.
Auteurs : Elizabeth C. Travis [Nouvelle-Zélande] ; Sarah Shugg [Nouvelle-Zélande] ; Winston M. Mcewan [Nouvelle-Zélande]Source :
- ANZ journal of surgery [ 1445-2197 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Aisselle, Facteurs temps, Femelle, Humains, Lymphadénectomie (effets indésirables), Lymphoedème (), Lymphoedème (étiologie), Membre supérieur (), Mâle, Noeuds lymphatiques (transplantation), Projets pilotes, Sujet âgé, Transplantation de tissu (), Études de suivi, Études prospectives.
- MESH :
- effets indésirables : Lymphadénectomie.
- étiologie : Lymphoedème, Noeuds lymphatiques.
- Adulte, Adulte d'âge moyen, Aisselle, Facteurs temps, Femelle, Humains, Lymphoedème, Membre supérieur, Mâle, Projets pilotes, Sujet âgé, Transplantation de tissu, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Adult, Aged, Axilla, Female, Follow-Up Studies, Humans, Lymph Node Excision (adverse effects), Lymph Nodes (transplantation), Lymphedema (etiology), Lymphedema (surgery), Male, Middle Aged, Pilot Projects, Prospective Studies, Time Factors, Tissue Transplantation (methods), Upper Extremity (blood supply).
- MESH :
- adverse effects : Lymph Node Excision.
- blood supply : Upper Extremity.
- etiology : Lymphedema.
- methods : Tissue Transplantation.
- surgery : Lymphedema.
- transplantation : Lymph Nodes.
- Adult, Aged, Axilla, Female, Follow-Up Studies, Humans, Male, Middle Aged, Pilot Projects, Prospective Studies, Time Factors.
Abstract
Microvascular lymph node transfer has been shown to improve the severity of lymphoedema. However, microvascular surgery is not suitable for all patients. Simple lymph node grafting does not require general anaesthetic or significant surgical resources and is a technique that has been tested in animal models only until this point. Our hypothesis is that the transplanted lymph nodes integrate into the lymphovascular system and function as a 'pump', directly pumping interstitial fluid back into the venous system.
DOI: 10.1111/ans.13171
PubMed: 25982238
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:25982238Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lymph node grafting in the treatment of upper limb lymphoedema: a clinical trial.</title><author><name sortKey="Travis, Elizabeth C" sort="Travis, Elizabeth C" uniqKey="Travis E" first="Elizabeth C" last="Travis">Elizabeth C. Travis</name><affiliation wicri:level="1"><nlm:affiliation>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton</wicri:regionArea><wicri:noRegion>Hamilton</wicri:noRegion></affiliation></author><author><name sortKey="Shugg, Sarah" sort="Shugg, Sarah" uniqKey="Shugg S" first="Sarah" last="Shugg">Sarah Shugg</name><affiliation wicri:level="1"><nlm:affiliation>Plastic and Reconstructive Surgery Department, Hutt Hospital, Wellington, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Plastic and Reconstructive Surgery Department, Hutt Hospital, Wellington</wicri:regionArea><wicri:noRegion>Wellington</wicri:noRegion></affiliation></author><author><name sortKey="Mcewan, Winston M" sort="Mcewan, Winston M" uniqKey="Mcewan W" first="Winston M" last="Mcewan">Winston M. Mcewan</name><affiliation wicri:level="1"><nlm:affiliation>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton</wicri:regionArea><wicri:noRegion>Hamilton</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25982238</idno><idno type="pmid">25982238</idno><idno type="doi">10.1111/ans.13171</idno><idno type="wicri:Area/PubMed/Corpus">000E87</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E87</idno><idno type="wicri:Area/PubMed/Curation">000E87</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E87</idno><idno type="wicri:Area/PubMed/Checkpoint">000E87</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000E87</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Lymph node grafting in the treatment of upper limb lymphoedema: a clinical trial.</title><author><name sortKey="Travis, Elizabeth C" sort="Travis, Elizabeth C" uniqKey="Travis E" first="Elizabeth C" last="Travis">Elizabeth C. Travis</name><affiliation wicri:level="1"><nlm:affiliation>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton</wicri:regionArea><wicri:noRegion>Hamilton</wicri:noRegion></affiliation></author><author><name sortKey="Shugg, Sarah" sort="Shugg, Sarah" uniqKey="Shugg S" first="Sarah" last="Shugg">Sarah Shugg</name><affiliation wicri:level="1"><nlm:affiliation>Plastic and Reconstructive Surgery Department, Hutt Hospital, Wellington, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Plastic and Reconstructive Surgery Department, Hutt Hospital, Wellington</wicri:regionArea><wicri:noRegion>Wellington</wicri:noRegion></affiliation></author><author><name sortKey="Mcewan, Winston M" sort="Mcewan, Winston M" uniqKey="Mcewan W" first="Winston M" last="Mcewan">Winston M. Mcewan</name><affiliation wicri:level="1"><nlm:affiliation>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton, New Zealand.</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton</wicri:regionArea><wicri:noRegion>Hamilton</wicri:noRegion></affiliation></author></analytic><series><title level="j">ANZ journal of surgery</title><idno type="eISSN">1445-2197</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Axilla</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Lymph Node Excision (adverse effects)</term><term>Lymph Nodes (transplantation)</term><term>Lymphedema (etiology)</term><term>Lymphedema (surgery)</term><term>Male</term><term>Middle Aged</term><term>Pilot Projects</term><term>Prospective Studies</term><term>Time Factors</term><term>Tissue Transplantation (methods)</term><term>Upper Extremity (blood supply)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Aisselle</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lymphadénectomie (effets indésirables)</term><term>Lymphoedème ()</term><term>Lymphoedème (étiologie)</term><term>Membre supérieur ()</term><term>Mâle</term><term>Noeuds lymphatiques (transplantation)</term><term>Projets pilotes</term><term>Sujet âgé</term><term>Transplantation de tissu ()</term><term>Études de suivi</term><term>Études prospectives</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lymph Node Excision</term></keywords><keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Upper Extremity</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lymphadénectomie</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Tissue Transplantation</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="transplantation" xml:lang="en"><term>Lymph Nodes</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term><term>Noeuds lymphatiques</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Axilla</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pilot Projects</term><term>Prospective Studies</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Aisselle</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lymphoedème</term><term>Membre supérieur</term><term>Mâle</term><term>Projets pilotes</term><term>Sujet âgé</term><term>Transplantation de tissu</term><term>Études de suivi</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Microvascular lymph node transfer has been shown to improve the severity of lymphoedema. However, microvascular surgery is not suitable for all patients. Simple lymph node grafting does not require general anaesthetic or significant surgical resources and is a technique that has been tested in animal models only until this point. Our hypothesis is that the transplanted lymph nodes integrate into the lymphovascular system and function as a 'pump', directly pumping interstitial fluid back into the venous system.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25982238</PMID><DateCreated><Year>2015</Year><Month>09</Month><Day>03</Day></DateCreated><DateCompleted><Year>2016</Year><Month>04</Month><Day>05</Day></DateCompleted><DateRevised><Year>2015</Year><Month>09</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1445-2197</ISSN><JournalIssue CitedMedium="Internet"><Volume>85</Volume><Issue>9</Issue><PubDate><Year>2015</Year><Month>Sep</Month></PubDate></JournalIssue><Title>ANZ journal of surgery</Title><ISOAbbreviation>ANZ J Surg</ISOAbbreviation></Journal><ArticleTitle>Lymph node grafting in the treatment of upper limb lymphoedema: a clinical trial.</ArticleTitle><Pagination><MedlinePgn>631-5</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/ans.13171</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Microvascular lymph node transfer has been shown to improve the severity of lymphoedema. However, microvascular surgery is not suitable for all patients. Simple lymph node grafting does not require general anaesthetic or significant surgical resources and is a technique that has been tested in animal models only until this point. Our hypothesis is that the transplanted lymph nodes integrate into the lymphovascular system and function as a 'pump', directly pumping interstitial fluid back into the venous system.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We hypothesized that lymph node grafting would improve lymphoedema with a low risk of complications. The procedure was performed in a day surgery setting under local anaesthetic with sedation. Two lymph nodes were harvested from the groin and grafted into subcutaneous tissue on the volar aspect of the affected limb at supratrochlear and wrist levels.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We found that nine of 10 patients reported a subjective and/or functional improvement in their lymphoedema, including an improvement in hand function and tissue feel. Truncal cone calculation volumes showed an overall decrease in affected limb volume of 89.7 mL (standard deviation = 136.5). Furthermore, follow-up lymphoscintigram imaging on one patient demonstrated viability and function of the implanted node.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">We conclude that this is a safe procedure and should be further investigated as an alternative to a microsurgical procedure as a treatment for upper limb lymphoedema. Further research with a larger sample size is needed to confirm the findings of this pilot study.</AbstractText><CopyrightInformation>© 2015 Royal Australasian College of Surgeons.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Travis</LastName><ForeName>Elizabeth C</ForeName><Initials>EC</Initials><AffiliationInfo><Affiliation>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton, New Zealand.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Shugg</LastName><ForeName>Sarah</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Plastic and Reconstructive Surgery Department, Hutt Hospital, Wellington, New Zealand.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McEwan</LastName><ForeName>Winston M</ForeName><Initials>WM</Initials><AffiliationInfo><Affiliation>Plastic and Reconstructive Surgery Department, Waikato Hospital, Hamilton, New Zealand.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ANZCTR</DataBankName><AccessionNumberList><AccessionNumber>ACTRN12613001116718</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>Australia</Country><MedlineTA>ANZ J Surg</MedlineTA><NlmUniqueID>101086634</NlmUniqueID><ISSNLinking>1445-1433</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>ANZ J Surg. 2015 Sep;85(9):598</RefSource><PMID Version="1">26332804</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001365" MajorTopicYN="N">Axilla</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008197" MajorTopicYN="N">Lymph Node Excision</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008198" MajorTopicYN="N">Lymph Nodes</DescriptorName><QualifierName UI="Q000637" MajorTopicYN="Y">transplantation</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010865" MajorTopicYN="N">Pilot Projects</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016378" MajorTopicYN="N">Tissue Transplantation</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D034941" MajorTopicYN="N">Upper Extremity</DescriptorName><QualifierName UI="Q000098" MajorTopicYN="Y">blood supply</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">axillary dissection</Keyword><Keyword MajorTopicYN="N">breast cancer</Keyword><Keyword MajorTopicYN="N">lymph node</Keyword><Keyword MajorTopicYN="N">lymph node grafting</Keyword><Keyword MajorTopicYN="N">lymphoedema</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>03</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>5</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>5</Month><Day>20</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>4</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25982238</ArticleId><ArticleId IdType="doi">10.1111/ans.13171</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Nouvelle-Zélande</li></country></list><tree><country name="Nouvelle-Zélande"><noRegion><name sortKey="Travis, Elizabeth C" sort="Travis, Elizabeth C" uniqKey="Travis E" first="Elizabeth C" last="Travis">Elizabeth C. Travis</name></noRegion><name sortKey="Mcewan, Winston M" sort="Mcewan, Winston M" uniqKey="Mcewan W" first="Winston M" last="Mcewan">Winston M. Mcewan</name><name sortKey="Shugg, Sarah" sort="Shugg, Sarah" uniqKey="Shugg S" first="Sarah" last="Shugg">Sarah Shugg</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E28 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000E28 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:25982238
|texte= Lymph node grafting in the treatment of upper limb lymphoedema: a clinical trial.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:25982238" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |