HAART in hand: The change in Kaposi's sarcoma presentation in KwaZulu-Natal, South Africa.
Identifieur interne : 000888 ( PubMed/Checkpoint ); précédent : 000887; suivant : 000889HAART in hand: The change in Kaposi's sarcoma presentation in KwaZulu-Natal, South Africa.
Auteurs : Levashni Naidoo [Afrique du Sud] ; Judith S. Jacobson ; Alfred I. Neugut ; Ncoza C. Dlova ; Anisa MosamSource :
- South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde [ 0256-9574 ] ; 2016.
Abstract
HIV/AIDS-related Kaposi's sarcoma (HIV-KS) is a public health problem in South Africa (SA). It is AIDS defining. There have been no studies evaluating its prevalence since the national roll-out of highly active antiretroviral therapy (HAART).
PubMed: 27245729
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">HAART in hand: The change in Kaposi's sarcoma presentation in KwaZulu-Natal, South Africa.</title><author><name sortKey="Naidoo, Levashni" sort="Naidoo, Levashni" uniqKey="Naidoo L" first="Levashni" last="Naidoo">Levashni Naidoo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. levashni.naidoo@yahoo.com.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Department of Dermatology, School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Jacobson, Judith S" sort="Jacobson, Judith S" uniqKey="Jacobson J" first="Judith S" last="Jacobson">Judith S. Jacobson</name></author><author><name sortKey="Neugut, Alfred I" sort="Neugut, Alfred I" uniqKey="Neugut A" first="Alfred I" last="Neugut">Alfred I. Neugut</name></author><author><name sortKey="Dlova, Ncoza C" sort="Dlova, Ncoza C" uniqKey="Dlova N" first="Ncoza C" last="Dlova">Ncoza C. Dlova</name></author><author><name sortKey="Mosam, Anisa" sort="Mosam, Anisa" uniqKey="Mosam A" first="Anisa" last="Mosam">Anisa Mosam</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2016">2016</date><idno type="RBID">pubmed:27245729</idno><idno type="pmid">27245729</idno><idno type="wicri:Area/PubMed/Corpus">000798</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000798</idno><idno type="wicri:Area/PubMed/Curation">000798</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000798</idno><idno type="wicri:Area/PubMed/Checkpoint">000798</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000798</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">HAART in hand: The change in Kaposi's sarcoma presentation in KwaZulu-Natal, South Africa.</title><author><name sortKey="Naidoo, Levashni" sort="Naidoo, Levashni" uniqKey="Naidoo L" first="Levashni" last="Naidoo">Levashni Naidoo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. levashni.naidoo@yahoo.com.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Department of Dermatology, School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Jacobson, Judith S" sort="Jacobson, Judith S" uniqKey="Jacobson J" first="Judith S" last="Jacobson">Judith S. Jacobson</name></author><author><name sortKey="Neugut, Alfred I" sort="Neugut, Alfred I" uniqKey="Neugut A" first="Alfred I" last="Neugut">Alfred I. Neugut</name></author><author><name sortKey="Dlova, Ncoza C" sort="Dlova, Ncoza C" uniqKey="Dlova N" first="Ncoza C" last="Dlova">Ncoza C. Dlova</name></author><author><name sortKey="Mosam, Anisa" sort="Mosam, Anisa" uniqKey="Mosam A" first="Anisa" last="Mosam">Anisa Mosam</name></author></analytic><series><title level="j">South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde</title><idno type="ISSN">0256-9574</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">HIV/AIDS-related Kaposi's sarcoma (HIV-KS) is a public health problem in South Africa (SA). It is AIDS defining. There have been no studies evaluating its prevalence since the national roll-out of highly active antiretroviral therapy (HAART).</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">27245729</PMID><DateCreated><Year>2016</Year><Month>06</Month><Day>01</Day></DateCreated><DateRevised><Year>2017</Year><Month>05</Month><Day>01</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">0256-9574</ISSN><JournalIssue CitedMedium="Print"><Volume>106</Volume><Issue>6</Issue><PubDate><Year>2016</Year><Month>May</Month><Day>11</Day></PubDate></JournalIssue><Title>South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde</Title><ISOAbbreviation>S. Afr. Med. J.</ISOAbbreviation></Journal><ArticleTitle>HAART in hand: The change in Kaposi's sarcoma presentation in KwaZulu-Natal, South Africa.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.7196/SAMJ.2016.v106i6.10333</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">HIV/AIDS-related Kaposi's sarcoma (HIV-KS) is a public health problem in South Africa (SA). It is AIDS defining. There have been no studies evaluating its prevalence since the national roll-out of highly active antiretroviral therapy (HAART).</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the effect of HAART on the disease profile of HIV-KS in KwaZulu-Natal Province (KZN), SA.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Charts of patients with histologically confirmed HIV-KS were reviewed at an oncology clinic in KZN. The significance of associations of HAART with age, gender, CD4 count, urban/rural residence, fungating lesions, ulceration and lymphoedema, and treatment delay, was determined by t-tests for normally distributed continuous variables and χ2 tests for categorical variables. Logistic regression models were used to analyse the association of HAART with CD4 count.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Of 198 patients, 194 were documented as HIV-positive; 168 (86.6%) were on HAART at the time of their KS diagnosis. The mean CD4 count of 266 cells/μL was higher than that in previous studies at this site. The mean age at presentation was 36.6 (standard deviation 10.1) years. Females presented at a younger mean age than males (p<0.001). The mean age of females on HAART was 34.7 years and that of males 39.0 years (p=0.003). HAART-naive patients were three times more likely than those receiving HAART (15.4% v. 4.8%) to have visceral involvement (p=0.03).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">HAART use has resulted in outcome improvement. Mean age at presentation has increased in the group as a whole and for females in particular. The trend in mean CD4 counts has shown positive growth. Females no longer shoulder a disproportionate burden of disease.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Naidoo</LastName><ForeName>Levashni</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Dermatology, School of Clinical Medicine, College of Health Sciences, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. levashni.naidoo@yahoo.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jacobson</LastName><ForeName>Judith S</ForeName><Initials>JS</Initials></Author><Author ValidYN="Y"><LastName>Neugut</LastName><ForeName>Alfred I</ForeName><Initials>AI</Initials></Author><Author ValidYN="Y"><LastName>Dlova</LastName><ForeName>Ncoza C</ForeName><Initials>NC</Initials></Author><Author ValidYN="Y"><LastName>Mosam</LastName><ForeName>Anisa</ForeName><Initials>A</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>05</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>South Africa</Country><MedlineTA>S Afr Med J</MedlineTA><NlmUniqueID>0404520</NlmUniqueID></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>11</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>11</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>6</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>6</Month><Day>2</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>6</Month><Day>2</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">27245729</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Afrique du Sud</li></country></list><tree><noCountry><name sortKey="Dlova, Ncoza C" sort="Dlova, Ncoza C" uniqKey="Dlova N" first="Ncoza C" last="Dlova">Ncoza C. Dlova</name><name sortKey="Jacobson, Judith S" sort="Jacobson, Judith S" uniqKey="Jacobson J" first="Judith S" last="Jacobson">Judith S. Jacobson</name><name sortKey="Mosam, Anisa" sort="Mosam, Anisa" uniqKey="Mosam A" first="Anisa" last="Mosam">Anisa Mosam</name><name sortKey="Neugut, Alfred I" sort="Neugut, Alfred I" uniqKey="Neugut A" first="Alfred I" last="Neugut">Alfred I. Neugut</name></noCountry><country name="Afrique du Sud"><noRegion><name sortKey="Naidoo, Levashni" sort="Naidoo, Levashni" uniqKey="Naidoo L" first="Levashni" last="Naidoo">Levashni Naidoo</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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