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Longitudinal monitoring of the head and neck lymphatics in response to surgery and radiation.

Identifieur interne : 000266 ( PubMed/Checkpoint ); précédent : 000265; suivant : 000267

Longitudinal monitoring of the head and neck lymphatics in response to surgery and radiation.

Auteurs : John C. Rasmussen [États-Unis] ; I-Chih Tan [États-Unis] ; Syed Naqvi [États-Unis] ; Melissa B. Aldrich [États-Unis] ; Erik A. Maus [États-Unis] ; Angel I. Blanco [États-Unis] ; Ron J. Karni [États-Unis] ; Eva M. Sevick-Muraca [États-Unis]

Source :

RBID : pubmed:28263428

Abstract

The lymphatic vasculature provides a route for cancer metastases, and its dysfunction after cancer treatment can result in lymphedema. However, changes in the lymphatics before, during, and after surgery and radiation remain unclear.

DOI: 10.1002/hed.24750
PubMed: 28263428


Affiliations:


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pubmed:28263428

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<AbstractText Label="METHODS" NlmCategory="METHODS">Near-infrared fluorescence lymphatic imaging was performed before and after lymph node dissection and fractionated radiotherapy to assess changes in external lymphatic function.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Patients who underwent both lymph node dissection and radiotherapy developed lymphatic dermal backflow on treated sides ranging from days after the start of radiotherapy to weeks after its completion, whereas contralateral regions that were not associated with lymph node dissection but also treated with radiotherapy experienced no such changes in external lymphatic anatomies.</AbstractText>
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