LymphedemaV1, PubMed, Checkpoint, bibRecord, 000016

Yellow nail syndrome: a review.

Identifieur interne : 000016 ( PubMed/Checkpoint ); précédent : 000015; suivant : 000017

Yellow nail syndrome: a review.

Auteurs : Stéphane Vignes [France] ; Robert Baran [France]

Source :

Orphanet journal of rare diseases [ 1750-1172 ] ; 2017.

RBID : pubmed:28241848

Abstract

Yellow nail syndrome (YNS; OMIM 153300, ORPHA662) is a very rare disorder that almost always occurs after 50 years of age but a juvenile or familial form has also been observed. YNS is diagnosed based on a triad associating yellow nail discoloration, pulmonary manifestations (chronic cough, bronchiectasia, pleural effusion) and lower limb lymphedema. Chronic sinusitis is frequently associated with the triad. YNS etiology remains unknown but a role of lymphatic impairment is usually evoked. YNS is more frequently isolated but may be associated in rare cases with autoimmune diseases, other clinical manifestations implicating lymphatic functions or cancer and, hence, is also considered a paraneoplastic syndrome. YNS management is symptomatic and not codified. YNS can resolve spontaneously. Oral vitamin E alone or even better when associated with triazole antifungals may achieve partial or total disappearance of nail discoloration. Pleural effusion can be treated surgically, with decortication/pleurectomy or pleurodesis. Antibiotic prophylaxis is prescribed for bronchiectasia with chronic sputum production. Lymphedema treatment is based on low-stretch bandages and the wearing of elastic compression garments combined with skin care, exercises and, as needed, manual lymph drainage.

DOI: 10.1186/s13023-017-0594-4
PubMed: 28241848

Affiliations:

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<front><div type="abstract" xml:lang="en">Yellow nail syndrome (YNS; OMIM 153300, ORPHA662) is a very rare disorder that almost always occurs after 50 years of age but a juvenile or familial form has also been observed. YNS is diagnosed based on a triad associating yellow nail discoloration, pulmonary manifestations (chronic cough, bronchiectasia, pleural effusion) and lower limb lymphedema. Chronic sinusitis is frequently associated with the triad. YNS etiology remains unknown but a role of lymphatic impairment is usually evoked. YNS is more frequently isolated but may be associated in rare cases with autoimmune diseases, other clinical manifestations implicating lymphatic functions or cancer and, hence, is also considered a paraneoplastic syndrome. YNS management is symptomatic and not codified. YNS can resolve spontaneously. Oral vitamin E alone or even better when associated with triazole antifungals may achieve partial or total disappearance of nail discoloration. Pleural effusion can be treated surgically, with decortication/pleurectomy or pleurodesis. Antibiotic prophylaxis is prescribed for bronchiectasia with chronic sputum production. Lymphedema treatment is based on low-stretch bandages and the wearing of elastic compression garments combined with skin care, exercises and, as needed, manual lymph drainage.</div>
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<Abstract><AbstractText>Yellow nail syndrome (YNS; OMIM 153300, ORPHA662) is a very rare disorder that almost always occurs after 50 years of age but a juvenile or familial form has also been observed. YNS is diagnosed based on a triad associating yellow nail discoloration, pulmonary manifestations (chronic cough, bronchiectasia, pleural effusion) and lower limb lymphedema. Chronic sinusitis is frequently associated with the triad. YNS etiology remains unknown but a role of lymphatic impairment is usually evoked. YNS is more frequently isolated but may be associated in rare cases with autoimmune diseases, other clinical manifestations implicating lymphatic functions or cancer and, hence, is also considered a paraneoplastic syndrome. YNS management is symptomatic and not codified. YNS can resolve spontaneously. Oral vitamin E alone or even better when associated with triazole antifungals may achieve partial or total disappearance of nail discoloration. Pleural effusion can be treated surgically, with decortication/pleurectomy or pleurodesis. Antibiotic prophylaxis is prescribed for bronchiectasia with chronic sputum production. Lymphedema treatment is based on low-stretch bandages and the wearing of elastic compression garments combined with skin care, exercises and, as needed, manual lymph drainage.</AbstractText>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Lymphedema</Keyword>
<Keyword MajorTopicYN="N">Respiratory manifestations</Keyword>
<Keyword MajorTopicYN="N">Review</Keyword>
<Keyword MajorTopicYN="N">Sinusitis</Keyword>
<Keyword MajorTopicYN="N">Yellow nail syndrome</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>10</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2017</Year>
<Month>02</Month>
<Day>21</Day>
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<PubMedPubDate PubStatus="entrez"><Year>2017</Year>
<Month>3</Month>
<Day>1</Day>
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<PubMedPubDate PubStatus="pubmed"><Year>2017</Year>
<Month>3</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>3</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">28241848</ArticleId>
<ArticleId IdType="doi">10.1186/s13023-017-0594-4</ArticleId>
<ArticleId IdType="pii">10.1186/s13023-017-0594-4</ArticleId>
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<affiliations><list><country><li>France</li>
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<region><li>Provence-Alpes-Côte d'Azur</li>
<li>Île-de-France</li>
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<settlement><li>Cannes</li>
<li>Paris</li>
</settlement>
</list>
<tree><country name="France"><region name="Île-de-France"><name sortKey="Vignes, Stephane" sort="Vignes, Stephane" uniqKey="Vignes S" first="Stéphane" last="Vignes">Stéphane Vignes</name>
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<name sortKey="Baran, Robert" sort="Baran, Robert" uniqKey="Baran R" first="Robert" last="Baran">Robert Baran</name>
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	Serveur d'exploration sur le lymphœdème
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Yellow nail syndrome: a review.

Yellow nail syndrome: a review.

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