Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication
Identifieur interne : 004946 ( Pmc/Curation ); précédent : 004945; suivant : 004947Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication
Auteurs : Jing Xu [République populaire de Chine] ; Elan Yang [République populaire de Chine] ; Nan-Ze Yu [République populaire de Chine] ; Xiao Long [République populaire de Chine]Source :
- Chinese Medical Journal [ 0366-6999 ] ; 2017.
Abstract
Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors.
The data analyzed in this review were searched from articles included in PubMed and EMBASE databases.
The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.
The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.
Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.
Url:
DOI: 10.4103/0366-6999.209896
PubMed: 28685723
PubMed Central: 5520560
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :004947
Links to Exploration step
PMC:5520560Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication</title><author><name sortKey="Xu, Jing" sort="Xu, Jing" uniqKey="Xu J" first="Jing" last="Xu">Jing Xu</name><affiliation wicri:level="1"><nlm:aff id="aff1">Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Peking Union Medical College, Beijing 100730</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Elan" sort="Yang, Elan" uniqKey="Yang E" first="Elan" last="Yang">Elan Yang</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Nan Ze" sort="Yu, Nan Ze" uniqKey="Yu N" first="Nan-Ze" last="Yu">Nan-Ze Yu</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730</wicri:regionArea></affiliation></author><author><name sortKey="Long, Xiao" sort="Long, Xiao" uniqKey="Long X" first="Xiao" last="Long">Xiao Long</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28685723</idno><idno type="pmc">5520560</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520560</idno><idno type="RBID">PMC:5520560</idno><idno type="doi">10.4103/0366-6999.209896</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">004947</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004947</idno><idno type="wicri:Area/Pmc/Curation">004946</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004946</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication</title><author><name sortKey="Xu, Jing" sort="Xu, Jing" uniqKey="Xu J" first="Jing" last="Xu">Jing Xu</name><affiliation wicri:level="1"><nlm:aff id="aff1">Peking Union Medical College, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Peking Union Medical College, Beijing 100730</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Elan" sort="Yang, Elan" uniqKey="Yang E" first="Elan" last="Yang">Elan Yang</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730</wicri:regionArea></affiliation></author><author><name sortKey="Yu, Nan Ze" sort="Yu, Nan Ze" uniqKey="Yu N" first="Nan-Ze" last="Yu">Nan-Ze Yu</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730</wicri:regionArea></affiliation></author><author><name sortKey="Long, Xiao" sort="Long, Xiao" uniqKey="Long X" first="Xiao" last="Long">Xiao Long</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730</wicri:regionArea></affiliation></author></analytic><series><title level="j">Chinese Medical Journal</title><idno type="ISSN">0366-6999</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Objective:</title><p>Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors.</p></sec><sec id="st2"><title>Data Sources:</title><p>The data analyzed in this review were searched from articles included in PubMed and EMBASE databases.</p></sec><sec id="st3"><title>Study Selection:</title><p>The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.</p></sec><sec id="st4"><title>Results:</title><p>The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.</p></sec><sec id="st5"><title>Conclusions:</title><p>Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Adegbidi, H" uniqKey="Adegbidi H">H Adegbidi</name></author><author><name sortKey="Atadokpede, F" uniqKey="Atadokpede F">F Atadokpede</name></author><author><name sortKey="Do Ango Padonou, F" uniqKey="Do Ango Padonou F">F do Ango-Padonou</name></author><author><name sortKey="Yedomon, H" uniqKey="Yedomon H">H Yedomon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kombate, K" uniqKey="Kombate K">K Kombate</name></author><author><name sortKey="Pitche, P" uniqKey="Pitche P">P Pitche</name></author><author><name sortKey="Tchangai Walla, K" uniqKey="Tchangai Walla K">K Tchangai-Walla</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Cp" uniqKey="Lee C">CP Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, Jj" uniqKey="Brown J">JJ Brown</name></author><author><name sortKey="Bayat, A" uniqKey="Bayat A">A Bayat</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arno, Ai" uniqKey="Arno A">AI Arno</name></author><author><name sortKey="Gauglitz, Gg" uniqKey="Gauglitz G">GG Gauglitz</name></author><author><name sortKey="Barret, Jp" uniqKey="Barret J">JP Barret</name></author><author><name sortKey="Jeschke, Mg" uniqKey="Jeschke M">MG Jeschke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Al Attar, A" uniqKey="Al Attar A">A Al-Attar</name></author><author><name sortKey="Mess, S" uniqKey="Mess S">S Mess</name></author><author><name sortKey="Thomassen, Jm" uniqKey="Thomassen J">JM Thomassen</name></author><author><name sortKey="Kauffman, Cl" uniqKey="Kauffman C">CL Kauffman</name></author><author><name sortKey="Davison, Sp" uniqKey="Davison S">SP Davison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shin, Jy" uniqKey="Shin J">JY Shin</name></author><author><name sortKey="Lee, Jw" uniqKey="Lee J">JW Lee</name></author><author><name sortKey="Roh, Sg" uniqKey="Roh S">SG Roh</name></author><author><name sortKey="Lee, Nh" uniqKey="Lee N">NH Lee</name></author><author><name sortKey="Yang, Km" uniqKey="Yang K">KM Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Bearman, R" uniqKey="De Bearman R">R De Bearman</name></author><author><name sortKey="Gourgerot, H" uniqKey="Gourgerot H">H Gourgerot</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Finzi, Ns" uniqKey="Finzi N">NS Finzi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Homans, J" uniqKey="Homans J">J Homans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levitt, W" uniqKey="Levitt W">W Levitt</name></author><author><name sortKey="Gillies, H" uniqKey="Gillies H">H Gillies</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rockwell, Wb" uniqKey="Rockwell W">WB Rockwell</name></author><author><name sortKey="Cohen, Ik" uniqKey="Cohen I">IK Cohen</name></author><author><name sortKey="Ehrlich, Hp" uniqKey="Ehrlich H">HP Ehrlich</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Kruger, A" uniqKey="Kruger A">A Kruger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cosman, B" uniqKey="Cosman B">B Cosman</name></author><author><name sortKey="Crikelair, Gf" uniqKey="Crikelair G">GF Crikelair</name></author><author><name sortKey="Ju, Dm" uniqKey="Ju D">DM Ju</name></author><author><name sortKey="Gaulin, Jc" uniqKey="Gaulin J">JC Gaulin</name></author><author><name sortKey="Lattes, R" uniqKey="Lattes R">R Lattes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, Jr" uniqKey="Brown J">JR Brown</name></author><author><name sortKey="Bromberg, Jh" uniqKey="Bromberg J">JH Bromberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Den Brenk, Ha" uniqKey="Van Den Brenk H">HA Van Den Brenk</name></author><author><name sortKey="Minty, Cc" uniqKey="Minty C">CC Minty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levy, Ds" uniqKey="Levy D">DS Levy</name></author><author><name sortKey="Salter, Mm" uniqKey="Salter M">MM Salter</name></author><author><name sortKey="Roth, Re" uniqKey="Roth R">RE Roth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carayon, A" uniqKey="Carayon A">A Carayon</name></author><author><name sortKey="Resillot, A" uniqKey="Resillot A">A Resillot</name></author><author><name sortKey="Souvestre" uniqKey="Souvestre">Souvestre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caronni, Ep" uniqKey="Caronni E">EP Caronni</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ollstein, Rn" uniqKey="Ollstein R">RN Ollstein</name></author><author><name sortKey="Siegel, Hw" uniqKey="Siegel H">HW Siegel</name></author><author><name sortKey="Gillooley, Jf" uniqKey="Gillooley J">JF Gillooley</name></author><author><name sortKey="Barsa, Jm" uniqKey="Barsa J">JM Barsa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kovalic, Jj" uniqKey="Kovalic J">JJ Kovalic</name></author><author><name sortKey="Perez, Ca" uniqKey="Perez C">CA Perez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Borok, Tl" uniqKey="Borok T">TL Borok</name></author><author><name sortKey="Bray, M" uniqKey="Bray M">M Bray</name></author><author><name sortKey="Sinclair, I" uniqKey="Sinclair I">I Sinclair</name></author><author><name sortKey="Plafker, J" uniqKey="Plafker J">J Plafker</name></author><author><name sortKey="Labirth, L" uniqKey="Labirth L">L LaBirth</name></author><author><name sortKey="Rollins, C" uniqKey="Rollins C">C Rollins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lo, Tc" uniqKey="Lo T">TC Lo</name></author><author><name sortKey="Seckel, Br" uniqKey="Seckel B">BR Seckel</name></author><author><name sortKey="Salzman, Fa" uniqKey="Salzman F">FA Salzman</name></author><author><name sortKey="Wright, Ka" uniqKey="Wright K">KA Wright</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kang, Km" uniqKey="Kang K">KM Kang</name></author><author><name sortKey="Choi, Ib" uniqKey="Choi I">IB Choi</name></author><author><name sortKey="Kim, Ia" uniqKey="Kim I">IA Kim</name></author><author><name sortKey="Jang, Jy" uniqKey="Jang J">JY Jang</name></author><author><name sortKey="Shinn, Ks" uniqKey="Shinn K">KS Shinn</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mitsuhashi, K" uniqKey="Mitsuhashi K">K Mitsuhashi</name></author><author><name sortKey="Miyashita, T" uniqKey="Miyashita T">T Miyashita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bertiere, Mn" uniqKey="Bertiere M">MN Bertiere</name></author><author><name sortKey="Jousset, C" uniqKey="Jousset C">C Jousset</name></author><author><name sortKey="Marin, Jl" uniqKey="Marin J">JL Marin</name></author><author><name sortKey="Baux, S" uniqKey="Baux S">S Baux</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Escarmant, P" uniqKey="Escarmant P">P Escarmant</name></author><author><name sortKey="Zimmermann, S" uniqKey="Zimmermann S">S Zimmermann</name></author><author><name sortKey="Amar, A" uniqKey="Amar A">A Amar</name></author><author><name sortKey="Ratoanina, Jl" uniqKey="Ratoanina J">JL Ratoanina</name></author><author><name sortKey="Moris, A" uniqKey="Moris A">A Moris</name></author><author><name sortKey="Azaloux, H" uniqKey="Azaloux H">H Azaloux</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garg, Mk" uniqKey="Garg M">MK Garg</name></author><author><name sortKey="Weiss, P" uniqKey="Weiss P">P Weiss</name></author><author><name sortKey="Sharma, Ak" uniqKey="Sharma A">AK Sharma</name></author><author><name sortKey="Gorla, Gr" uniqKey="Gorla G">GR Gorla</name></author><author><name sortKey="Jaggernauth, W" uniqKey="Jaggernauth W">W Jaggernauth</name></author><author><name sortKey="Yaparpalvi, R" uniqKey="Yaparpalvi R">R Yaparpalvi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guix, B" uniqKey="Guix B">B Guix</name></author><author><name sortKey="Henriquez, I" uniqKey="Henriquez I">I Henríquez</name></author><author><name sortKey="Andres, A" uniqKey="Andres A">A Andrés</name></author><author><name sortKey="Finestres, F" uniqKey="Finestres F">F Finestres</name></author><author><name sortKey="Tello, Ji" uniqKey="Tello J">JI Tello</name></author><author><name sortKey="Martinez, A" uniqKey="Martinez A">A Martínez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ogawa, R" uniqKey="Ogawa R">R Ogawa</name></author><author><name sortKey="Miyashita, T" uniqKey="Miyashita T">T Miyashita</name></author><author><name sortKey="Hyakusoku, H" uniqKey="Hyakusoku H">H Hyakusoku</name></author><author><name sortKey="Akaishi, S" uniqKey="Akaishi S">S Akaishi</name></author><author><name sortKey="Kuribayashi, S" uniqKey="Kuribayashi S">S Kuribayashi</name></author><author><name sortKey="Tateno, A" uniqKey="Tateno A">A Tateno</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baskar, R" uniqKey="Baskar R">R Baskar</name></author><author><name sortKey="Lee, Ka" uniqKey="Lee K">KA Lee</name></author><author><name sortKey="Yeo, R" uniqKey="Yeo R">R Yeo</name></author><author><name sortKey="Yeoh, Kw" uniqKey="Yeoh K">KW Yeoh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mustoe, Ta" uniqKey="Mustoe T">TA Mustoe</name></author><author><name sortKey="Cooter, Rd" uniqKey="Cooter R">RD Cooter</name></author><author><name sortKey="Gold, Mh" uniqKey="Gold M">MH Gold</name></author><author><name sortKey="Hobbs, Fd" uniqKey="Hobbs F">FD Hobbs</name></author><author><name sortKey="Ramelet, Aa" uniqKey="Ramelet A">AA Ramelet</name></author><author><name sortKey="Shakespeare, Pg" uniqKey="Shakespeare P">PG Shakespeare</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, Qq" uniqKey="Yang Q">QQ Yang</name></author><author><name sortKey="Yang, Ss" uniqKey="Yang S">SS Yang</name></author><author><name sortKey="Tan, Jl" uniqKey="Tan J">JL Tan</name></author><author><name sortKey="Luo, Gx" uniqKey="Luo G">GX Luo</name></author><author><name sortKey="He, Wf" uniqKey="He W">WF He</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caviggioli, F" uniqKey="Caviggioli F">F Caviggioli</name></author><author><name sortKey="Maione, L" uniqKey="Maione L">L Maione</name></author><author><name sortKey="Vinci, V" uniqKey="Vinci V">V Vinci</name></author><author><name sortKey="Klinger, M" uniqKey="Klinger M">M Klinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shen, J" uniqKey="Shen J">J Shen</name></author><author><name sortKey="Lian, X" uniqKey="Lian X">X Lian</name></author><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author><author><name sortKey="Wang, X" uniqKey="Wang X">X Wang</name></author><author><name sortKey="Hu, K" uniqKey="Hu K">K Hu</name></author><author><name sortKey="Hou, X" uniqKey="Hou X">X Hou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, Me" uniqKey="Jones M">ME Jones</name></author><author><name sortKey="Hardy, C" uniqKey="Hardy C">C Hardy</name></author><author><name sortKey="Ridgway, J" uniqKey="Ridgway J">J Ridgway</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eaton, Dj" uniqKey="Eaton D">DJ Eaton</name></author><author><name sortKey="Barber, E" uniqKey="Barber E">E Barber</name></author><author><name sortKey="Ferguson, L" uniqKey="Ferguson L">L Ferguson</name></author><author><name sortKey="Mark Simpson, G" uniqKey="Mark Simpson G">G Mark Simpson</name></author><author><name sortKey="Collis, Ch" uniqKey="Collis C">CH Collis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klumpar, Di" uniqKey="Klumpar D">DI Klumpar</name></author><author><name sortKey="Murray, Jc" uniqKey="Murray J">JC Murray</name></author><author><name sortKey="Anscher, M" uniqKey="Anscher M">M Anscher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Borok, Tl" uniqKey="Borok T">TL Borok</name></author><author><name sortKey="Bray, M" uniqKey="Bray M">M Bray</name></author><author><name sortKey="Sinclair, I" uniqKey="Sinclair I">I Sinclair</name></author><author><name sortKey="Plafker, J" uniqKey="Plafker J">J Plafker</name></author><author><name sortKey="Labirth, L" uniqKey="Labirth L">L LaBirth</name></author><author><name sortKey="Rollins, C" uniqKey="Rollins C">C Rollins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eaton, Dj" uniqKey="Eaton D">DJ Eaton</name></author><author><name sortKey="Barber, E" uniqKey="Barber E">E Barber</name></author><author><name sortKey="Ferguson, L" uniqKey="Ferguson L">L Ferguson</name></author><author><name sortKey="Mark Simpson, G" uniqKey="Mark Simpson G">G Mark Simpson</name></author><author><name sortKey="Collis, Ch" uniqKey="Collis C">CH Collis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, M" uniqKey="Li M">M Li</name></author><author><name sortKey="Li, Gf" uniqKey="Li G">GF Li</name></author><author><name sortKey="Hou, Xy" uniqKey="Hou X">XY Hou</name></author><author><name sortKey="Gao, H" uniqKey="Gao H">H Gao</name></author><author><name sortKey="Xu, Yg" uniqKey="Xu Y">YG Xu</name></author><author><name sortKey="Zhao, T" uniqKey="Zhao T">T Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flickinger, Jc" uniqKey="Flickinger J">JC Flickinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Duan, Q" uniqKey="Duan Q">Q Duan</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Luo, Z" uniqKey="Luo Z">Z Luo</name></author><author><name sortKey="Hu, C" uniqKey="Hu C">C Hu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Lz" uniqKey="Wang L">LZ Wang</name></author><author><name sortKey="Ding, Jp" uniqKey="Ding J">JP Ding</name></author><author><name sortKey="Yang, My" uniqKey="Yang M">MY Yang</name></author><author><name sortKey="Chen, B" uniqKey="Chen B">B Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, C" uniqKey="Song C">C Song</name></author><author><name sortKey="Wu, Hg" uniqKey="Wu H">HG Wu</name></author><author><name sortKey="Chang, H" uniqKey="Chang H">H Chang</name></author><author><name sortKey="Kim, Ih" uniqKey="Kim I">IH Kim</name></author><author><name sortKey="Ha, Sw" uniqKey="Ha S">SW Ha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seegenschmiedt, Mh" uniqKey="Seegenschmiedt M">MH Seegenschmiedt</name></author><author><name sortKey="Micke, O" uniqKey="Micke O">O Micke</name></author><author><name sortKey="Muecke, R" uniqKey="Muecke R">R Muecke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vila Capel, A" uniqKey="Vila Capel A">A Vila Capel</name></author><author><name sortKey="Vilar Palop, J" uniqKey="Vilar Palop J">J Vilar Palop</name></author><author><name sortKey="Pedro Olive, A" uniqKey="Pedro Olive A">A Pedro Olivé</name></author><author><name sortKey="Sanchez Reyes Fernandez, A" uniqKey="Sanchez Reyes Fernandez A">A Sánchez-Reyes Fernández</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Escarmant, P" uniqKey="Escarmant P">P Escarmant</name></author><author><name sortKey="Zimmermann, S" uniqKey="Zimmermann S">S Zimmermann</name></author><author><name sortKey="Amar, A" uniqKey="Amar A">A Amar</name></author><author><name sortKey="Ratoanina, Jl" uniqKey="Ratoanina J">JL Ratoanina</name></author><author><name sortKey="Moris, A" uniqKey="Moris A">A Moris</name></author><author><name sortKey="Azaloux, H" uniqKey="Azaloux H">H Azaloux</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Veen, Re" uniqKey="Veen R">RE Veen</name></author><author><name sortKey="Kal, Hb" uniqKey="Kal H">HB Kal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arnault, Jp" uniqKey="Arnault J">JP Arnault</name></author><author><name sortKey="Peiffert, D" uniqKey="Peiffert D">D Peiffert</name></author><author><name sortKey="Latarche, C" uniqKey="Latarche C">C Latarche</name></author><author><name sortKey="Chassagne, Jf" uniqKey="Chassagne J">JF Chassagne</name></author><author><name sortKey="Barbaud, A" uniqKey="Barbaud A">A Barbaud</name></author><author><name sortKey="Schmutz, Jl" uniqKey="Schmutz J">JL Schmutz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Leeuwen, Mc" uniqKey="Van Leeuwen M">MC van Leeuwen</name></author><author><name sortKey="Stokmans, Sc" uniqKey="Stokmans S">SC Stokmans</name></author><author><name sortKey="Bulstra, Ae" uniqKey="Bulstra A">AE Bulstra</name></author><author><name sortKey="Meijer, Ow" uniqKey="Meijer O">OW Meijer</name></author><author><name sortKey="Heymans, Mw" uniqKey="Heymans M">MW Heymans</name></author><author><name sortKey="Ket, Jc" uniqKey="Ket J">JC Ket</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guix, B" uniqKey="Guix B">B Guix</name></author><author><name sortKey="Finestres, F" uniqKey="Finestres F">F Finestres</name></author><author><name sortKey="Tello, J" uniqKey="Tello J">J Tello</name></author><author><name sortKey="Palma, C" uniqKey="Palma C">C Palma</name></author><author><name sortKey="Martinez, A" uniqKey="Martinez A">A Martinez</name></author><author><name sortKey="Guix, J" uniqKey="Guix J">J Guix</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bischof, M" uniqKey="Bischof M">M Bischof</name></author><author><name sortKey="Krempien, R" uniqKey="Krempien R">R Krempien</name></author><author><name sortKey="Debus, J" uniqKey="Debus J">J Debus</name></author><author><name sortKey="Treiber, M" uniqKey="Treiber M">M Treiber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hintz, Bl" uniqKey="Hintz B">BL Hintz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cosman, B" uniqKey="Cosman B">B Cosman</name></author><author><name sortKey="Wolff, M" uniqKey="Wolff M">M Wolff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Supe, Ss" uniqKey="Supe S">SS Supe</name></author><author><name sortKey="Supe, Sj" uniqKey="Supe S">SJ Supe</name></author><author><name sortKey="Rao, Sm" uniqKey="Rao S">SM Rao</name></author><author><name sortKey="Deka, Ac" uniqKey="Deka A">AC Deka</name></author><author><name sortKey="Deka, Bc" uniqKey="Deka B">BC Deka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wagner, W" uniqKey="Wagner W">W Wagner</name></author><author><name sortKey="Alfrink, M" uniqKey="Alfrink M">M Alfrink</name></author><author><name sortKey="Micke, O" uniqKey="Micke O">O Micke</name></author><author><name sortKey="Sch Fer, U" uniqKey="Sch Fer U">U Schäfer</name></author><author><name sortKey="Schuller, P" uniqKey="Schuller P">P Schüller</name></author><author><name sortKey="Willich, N" uniqKey="Willich N">N Willich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seegenschmiedt, Mh" uniqKey="Seegenschmiedt M">MH Seegenschmiedt</name></author><author><name sortKey="Micke, O" uniqKey="Micke O">O Micke</name></author><author><name sortKey="Willich, N" uniqKey="Willich N">N Willich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kal, Hb" uniqKey="Kal H">HB Kal</name></author><author><name sortKey="Veen, Re" uniqKey="Veen R">RE Veen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Enhamre, A" uniqKey="Enhamre A">A Enhamre</name></author><author><name sortKey="Hammar, H" uniqKey="Hammar H">H Hammar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ragoowansi, R" uniqKey="Ragoowansi R">R Ragoowansi</name></author><author><name sortKey="Cornes, Pg" uniqKey="Cornes P">PG Cornes</name></author><author><name sortKey="Moss, Al" uniqKey="Moss A">AL Moss</name></author><author><name sortKey="Glees, Jp" uniqKey="Glees J">JP Glees</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doornbos, Jf" uniqKey="Doornbos J">JF Doornbos</name></author><author><name sortKey="Stoffel, Tj" uniqKey="Stoffel T">TJ Stoffel</name></author><author><name sortKey="Hass, Ac" uniqKey="Hass A">AC Hass</name></author><author><name sortKey="Hussey, Dh" uniqKey="Hussey D">DH Hussey</name></author><author><name sortKey="Vigliotti, Ap" uniqKey="Vigliotti A">AP Vigliotti</name></author><author><name sortKey="Wen, Bc" uniqKey="Wen B">BC Wen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kal, Hb" uniqKey="Kal H">HB Kal</name></author><author><name sortKey="Veen, Re" uniqKey="Veen R">RE Veen</name></author><author><name sortKey="Jurgenliemk Schulz, Im" uniqKey="Jurgenliemk Schulz I">IM Jürgenliemk-Schulz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ship, Ag" uniqKey="Ship A">AG Ship</name></author><author><name sortKey="Weiss, Pr" uniqKey="Weiss P">PR Weiss</name></author><author><name sortKey="Mincer, Fr" uniqKey="Mincer F">FR Mincer</name></author><author><name sortKey="Wolkstein, W" uniqKey="Wolkstein W">W Wolkstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ogawa, R" uniqKey="Ogawa R">R Ogawa</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name></author><author><name sortKey="Akaishi, S" uniqKey="Akaishi S">S Akaishi</name></author><author><name sortKey="Dohi, T" uniqKey="Dohi T">T Dohi</name></author><author><name sortKey="Sugimoto, A" uniqKey="Sugimoto A">A Sugimoto</name></author><author><name sortKey="Kuribayashi, S" uniqKey="Kuribayashi S">S Kuribayashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakamoto, T" uniqKey="Sakamoto T">T Sakamoto</name></author><author><name sortKey="Oya, N" uniqKey="Oya N">N Oya</name></author><author><name sortKey="Shibuya, K" uniqKey="Shibuya K">K Shibuya</name></author><author><name sortKey="Nagata, Y" uniqKey="Nagata Y">Y Nagata</name></author><author><name sortKey="Hiraoka, M" uniqKey="Hiraoka M">M Hiraoka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Speranza, G" uniqKey="Speranza G">G Speranza</name></author><author><name sortKey="Sultanem, K" uniqKey="Sultanem K">K Sultanem</name></author><author><name sortKey="Muanza, T" uniqKey="Muanza T">T Muanza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fraunholz, Ib" uniqKey="Fraunholz I">IB Fraunholz</name></author><author><name sortKey="Gerstenhauer, A" uniqKey="Gerstenhauer A">A Gerstenhauer</name></author><author><name sortKey="Bottcher, Hd" uniqKey="Bottcher H">HD Böttcher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Viani, Ga" uniqKey="Viani G">GA Viani</name></author><author><name sortKey="Stefano, Ej" uniqKey="Stefano E">EJ Stefano</name></author><author><name sortKey="Afonso, Sl" uniqKey="Afonso S">SL Afonso</name></author><author><name sortKey="De Fendi, Li" uniqKey="De Fendi L">LI De Fendi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bentzen, Sm" uniqKey="Bentzen S">SM Bentzen</name></author><author><name sortKey="Thames, Hd" uniqKey="Thames H">HD Thames</name></author><author><name sortKey="Overgaard, M" uniqKey="Overgaard M">M Overgaard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffman, S" uniqKey="Hoffman S">S Hoffman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Norris, Je" uniqKey="Norris J">JE Norris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ogawa, R" uniqKey="Ogawa R">R Ogawa</name></author><author><name sortKey="Yoshitatsu, S" uniqKey="Yoshitatsu S">S Yoshitatsu</name></author><author><name sortKey="Yoshida, K" uniqKey="Yoshida K">K Yoshida</name></author><author><name sortKey="Miyashita, T" uniqKey="Miyashita T">T Miyashita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Biemans, Rg" uniqKey="Biemans R">RG Biemans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horton, Ce" uniqKey="Horton C">CE Horton</name></author><author><name sortKey="Crawford, J" uniqKey="Crawford J">J Crawford</name></author><author><name sortKey="Oakey, Rs" uniqKey="Oakey R">RS Oakey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Botwood, N" uniqKey="Botwood N">N Botwood</name></author><author><name sortKey="Lewanski, C" uniqKey="Lewanski C">C Lewanski</name></author><author><name sortKey="Lowdell, C" uniqKey="Lowdell C">C Lowdell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leer, Jw" uniqKey="Leer J">JW Leer</name></author><author><name sortKey="Van Houtte, P" uniqKey="Van Houtte P">P van Houtte</name></author><author><name sortKey="Seegenschmiedt, H" uniqKey="Seegenschmiedt H">H Seegenschmiedt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ogawa, R" uniqKey="Ogawa R">R Ogawa</name></author><author><name sortKey="Mitsuhashi, K" uniqKey="Mitsuhashi K">K Mitsuhashi</name></author><author><name sortKey="Hyakusoku, H" uniqKey="Hyakusoku H">H Hyakusoku</name></author><author><name sortKey="Miyashita, T" uniqKey="Miyashita T">T Miyashita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leer, Jw" uniqKey="Leer J">JW Leer</name></author><author><name sortKey="Van Houtte, P" uniqKey="Van Houtte P">P van Houtte</name></author><author><name sortKey="Davelaar, J" uniqKey="Davelaar J">J Davelaar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, J" uniqKey="Kim J">J Kim</name></author><author><name sortKey="Lee, Sh" uniqKey="Lee S">SH Lee</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Chin Med J (Engl)</journal-id><journal-id journal-id-type="iso-abbrev">Chin. Med. J</journal-id><journal-id journal-id-type="publisher-id">CMJ</journal-id><journal-title-group><journal-title>Chinese Medical Journal</journal-title></journal-title-group><issn pub-type="ppub">0366-6999</issn><publisher><publisher-name>Medknow Publications & Media Pvt Ltd</publisher-name><publisher-loc>India</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28685723</article-id><article-id pub-id-type="pmc">5520560</article-id><article-id pub-id-type="publisher-id">CMJ-130-1715</article-id><article-id pub-id-type="doi">10.4103/0366-6999.209896</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Xu</surname><given-names>Jing</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Yang</surname><given-names>Elan</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Yu</surname><given-names>Nan-Ze</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Long</surname><given-names>Xiao</given-names></name><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="corresp" rid="cor1"></xref></contrib></contrib-group><aff id="aff1"><label>1</label>Peking Union Medical College, Beijing 100730, China</aff><aff id="aff2"><label>2</label>Department of Plastic Surgery, Peking Union Medical College Hospital, Beijing 100730, China</aff><author-notes><corresp id="cor1"><bold>Address for correspondence:</bold> Dr. Xiao Long, Department of Plastic Surgery, Peking Union Medical College Hospital, Shuaifuyuan 1#, Beijing 100730, China E-Mail: <email xlink:href="pumclongxiao@126.com">pumclongxiao@126.com</email></corresp></author-notes><pub-date pub-type="ppub"><day>20</day><month>7</month><year>2017</year></pub-date><volume>130</volume><issue>14</issue><fpage>1715</fpage><lpage>1721</lpage><history><date date-type="received"><day>28</day><month>2</month><year>2017</year></date></history><permissions><copyright-statement>Copyright: © 2017 Chinese Medical Journal</copyright-statement><copyright-year>2017</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0"><license-p>This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.</license-p></license></permissions><abstract><sec id="st1"><title>Objective:</title><p>Radiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors.</p></sec><sec id="st2"><title>Data Sources:</title><p>The data analyzed in this review were searched from articles included in PubMed and EMBASE databases.</p></sec><sec id="st3"><title>Study Selection:</title><p>The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.</p></sec><sec id="st4"><title>Results:</title><p>The application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.</p></sec><sec id="st5"><title>Conclusions:</title><p>Both past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.</p></sec></abstract><kwd-group><kwd>Combination Therapy</kwd><kwd>Keloids</kwd><kwd>Radiation Therapy</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004946 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 004946 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Pmc
|étape= Curation
|type= RBID
|clé= PMC:5520560
|texte= Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:28685723" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |