Pain Management and Symptom-Oriented Drug Therapy in Palliative Care
Identifieur interne : 004779 ( Pmc/Curation ); précédent : 004778; suivant : 004780Pain Management and Symptom-Oriented Drug Therapy in Palliative Care
Auteurs : Carsten Klein ; Ute Lang ; Johannes Bükki ; Reinhard Sittl ; Christoph OstgatheSource :
- Breast Care [ 1661-3791 ] ; 2011.
Abstract
Patients with advanced life-limiting disease often suffer from symptoms that considerably impair their quality of life and that of their families. Palliative care aims to alleviate these symptoms by a multidimensional approach. Pharmacotherapy is an essential component. The objective of this review is to give an overview of symptom-oriented drug therapy for the most important symptoms in palliative care. Leading symptoms that affect quality of life include pain, dyspnea, nausea and emesis, weakness and disorientation. Careful examination and history taking help to understand the individual mechanisms underlying these symptoms. Specific pharmacotherapy provides an efficient way to achieve symptom control in the context of palliative care.
Url:
DOI: 10.1159/000324702
PubMed: 21547023
PubMed Central: 3083268
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PMC:3083268Le document en format XML
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<author><name sortKey="Klein, Carsten" sort="Klein, Carsten" uniqKey="Klein C" first="Carsten" last="Klein">Carsten Klein</name>
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<author><name sortKey="Lang, Ute" sort="Lang, Ute" uniqKey="Lang U" first="Ute" last="Lang">Ute Lang</name>
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<author><name sortKey="Bukki, Johannes" sort="Bukki, Johannes" uniqKey="Bukki J" first="Johannes" last="Bükki">Johannes Bükki</name>
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<author><name sortKey="Sittl, Reinhard" sort="Sittl, Reinhard" uniqKey="Sittl R" first="Reinhard" last="Sittl">Reinhard Sittl</name>
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<author><name sortKey="Ostgathe, Christoph" sort="Ostgathe, Christoph" uniqKey="Ostgathe C" first="Christoph" last="Ostgathe">Christoph Ostgathe</name>
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<author><name sortKey="Ostgathe, Christoph" sort="Ostgathe, Christoph" uniqKey="Ostgathe C" first="Christoph" last="Ostgathe">Christoph Ostgathe</name>
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<series><title level="j">Breast Care</title>
<idno type="ISSN">1661-3791</idno>
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<imprint><date when="2011">2011</date>
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<front><div type="abstract" xml:lang="en"><sec><title>Summary</title>
<p>Patients with advanced life-limiting disease often suffer from symptoms that considerably impair their quality of life and that of their families. Palliative care aims to alleviate these symptoms by a multidimensional approach. Pharmacotherapy is an essential component. The objective of this review is to give an overview of symptom-oriented drug therapy for the most important symptoms in palliative care. Leading symptoms that affect quality of life include pain, dyspnea, nausea and emesis, weakness and disorientation. Careful examination and history taking help to understand the individual mechanisms underlying these symptoms. Specific pharmacotherapy provides an efficient way to achieve symptom control in the context of palliative care.</p>
</sec>
</div>
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<pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Breast Care (Basel)</journal-id>
<journal-id journal-id-type="iso-abbrev">Breast Care (Basel)</journal-id>
<journal-id journal-id-type="publisher-id">BRC</journal-id>
<journal-title-group><journal-title>Breast Care</journal-title>
</journal-title-group>
<issn pub-type="ppub">1661-3791</issn>
<issn pub-type="epub">1661-3805</issn>
<publisher><publisher-name>S. Karger GmbH</publisher-name>
<publisher-loc>Lörracherstrasse 16 a, P.O. Box · Postfach · Case postale, D–79095, Freiburg, Germany · Deutschland · Allemagne, Phone: +49 761 45 20 70, Fax: +49 761 4 52 07 14, information@karger.de</publisher-loc>
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<article-id pub-id-type="doi">10.1159/000324702</article-id>
<article-id pub-id-type="publisher-id">brc0006-0027</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Review Article Übersichtsarbeit</subject>
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<title-group><article-title>Pain Management and Symptom-Oriented Drug Therapy in Palliative Care</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Klein</surname>
<given-names>Carsten</given-names>
</name>
<xref ref-type="corresp" rid="cor1">*</xref>
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<contrib contrib-type="author"><name><surname>Lang</surname>
<given-names>Ute</given-names>
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<contrib contrib-type="author"><name><surname>Bükki</surname>
<given-names>Johannes</given-names>
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<contrib contrib-type="author"><name><surname>Sittl</surname>
<given-names>Reinhard</given-names>
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<contrib contrib-type="author"><name><surname>Ostgathe</surname>
<given-names>Christoph</given-names>
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<aff>Division of Palliative Medicine, University of Erlangen, Germany</aff>
<author-notes><corresp id="cor1">*Dr. med. Carsten Klein, Division of Palliative Medicine, University of Erlangen, Krankenhausstrasse 12, 91054 Erlangen, Germany, Tel. +49 9131 853406-4, Fax -6, <email>carsten.klein@uk-erlangen.de</email>
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<pub-date pub-type="ppub"><month>2</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub"><day>22</day>
<month>2</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>1</day>
<month>2</month>
<year>2012</year>
</pub-date>
<pmc-comment> PMC Release delay is 12 months and 0 days and was based on the
. </pmc-comment>
<volume>6</volume>
<issue>1</issue>
<fpage>27</fpage>
<lpage>34</lpage>
<permissions><copyright-statement>Copyright © 2011 by S. Karger AG, Basel</copyright-statement>
<copyright-year>2011</copyright-year>
</permissions>
<abstract><sec><title>Summary</title>
<p>Patients with advanced life-limiting disease often suffer from symptoms that considerably impair their quality of life and that of their families. Palliative care aims to alleviate these symptoms by a multidimensional approach. Pharmacotherapy is an essential component. The objective of this review is to give an overview of symptom-oriented drug therapy for the most important symptoms in palliative care. Leading symptoms that affect quality of life include pain, dyspnea, nausea and emesis, weakness and disorientation. Careful examination and history taking help to understand the individual mechanisms underlying these symptoms. Specific pharmacotherapy provides an efficient way to achieve symptom control in the context of palliative care.</p>
</sec>
</abstract>
<trans-abstract xml:lang="de"><sec><title>Zusammenfassung</title>
<p>Palliativpatienten und damit auch ihre Angehörigen leiden häufig unter belastenden Symptomen, die nachhaltig die Lebensqualität beeinflussen. Die Palliativmedizin will diese belastenden Symptome mithilfe eines multidisziplinären Ansatzes lindern. Einen wesentlichen Baustein in der symptomorientierten Behandlung stellt die medikamentöse Therapie dar. Ziel des vorliegenden Artikels ist es, einen Überblick über die symptomorientierte Behandlung der wichtigsten Beschwerden im Bereich der Palliativmedizin zu geben. Zu diesen Symptomen gehören Schmerz, Luftnot, Übelkeit und Erbrechen, Schwäche und Verwirrtheit. Exakte Anamneseerhebung und Untersuchung helfen, die individuellen Mechanismen, die den vorliegenden Beschwerden zugrunde liegen, zu verstehen. Dadurch wird eine zielgerichtete medikamentöse Therapie zur Symptomkontrolle ermöglicht.</p>
</sec>
</trans-abstract>
<kwd-group><title>Keywords</title>
<kwd>Palliative care</kwd>
<kwd>Symptoms</kwd>
<kwd>Pain therapy</kwd>
<kwd>End of life</kwd>
<kwd>Opioids</kwd>
</kwd-group>
<counts><fig-count count="1"></fig-count>
<table-count count="4"></table-count>
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