To grow or not to grow: Hair morphogenesis and human genetic hair disorders
Identifieur interne : 003A40 ( Pmc/Curation ); précédent : 003A39; suivant : 003A41To grow or not to grow: Hair morphogenesis and human genetic hair disorders
Auteurs : Olivier Duverger ; Maria I. MorassoSource :
- Seminars in cell & developmental biology [ 1084-9521 ] ; 2013.
Abstract
Mouse models have greatly helped in elucidating the molecular mechanisms involved in hair formation and regeneration. Recent publications have reviewed the genes involved in mouse hair development based on the phenotype of transgenic, knockout and mutant animal models. While much of this information has been instrumental in determining molecular aspects of human hair development and cycling, mice exhibit a specific pattern of hair morphogenesis and hair distribution throughout the body that cannot be directly correlated to human hair. In this mini-review, we discuss specific aspects of human hair follicle development and present an up-to-date summary of human genetic disorders associated with abnormalities in hair follicle morphogenesis, structure or regeneration.
Url:
DOI: 10.1016/j.semcdb.2013.12.006
PubMed: 24361867
PubMed Central: 3988237
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">To grow or not to grow: Hair morphogenesis and human genetic hair disorders</title><author><name sortKey="Duverger, Olivier" sort="Duverger, Olivier" uniqKey="Duverger O" first="Olivier" last="Duverger">Olivier Duverger</name></author><author><name sortKey="Morasso, Maria I" sort="Morasso, Maria I" uniqKey="Morasso M" first="Maria I." last="Morasso">Maria I. Morasso</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24361867</idno><idno type="pmc">3988237</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988237</idno><idno type="RBID">PMC:3988237</idno><idno type="doi">10.1016/j.semcdb.2013.12.006</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">003A41</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003A41</idno><idno type="wicri:Area/Pmc/Curation">003A40</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003A40</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">To grow or not to grow: Hair morphogenesis and human genetic hair disorders</title><author><name sortKey="Duverger, Olivier" sort="Duverger, Olivier" uniqKey="Duverger O" first="Olivier" last="Duverger">Olivier Duverger</name></author><author><name sortKey="Morasso, Maria I" sort="Morasso, Maria I" uniqKey="Morasso M" first="Maria I." last="Morasso">Maria I. Morasso</name></author></analytic><series><title level="j">Seminars in cell & developmental biology</title><idno type="ISSN">1084-9521</idno><idno type="eISSN">1096-3634</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Mouse models have greatly helped in elucidating the molecular mechanisms involved in hair formation and regeneration. Recent publications have reviewed the genes involved in mouse hair development based on the phenotype of transgenic, knockout and mutant animal models. While much of this information has been instrumental in determining molecular aspects of human hair development and cycling, mice exhibit a specific pattern of hair morphogenesis and hair distribution throughout the body that cannot be directly correlated to human hair. In this mini-review, we discuss specific aspects of human hair follicle development and present an up-to-date summary of human genetic disorders associated with abnormalities in hair follicle morphogenesis, structure or regeneration.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9607332</journal-id><journal-id journal-id-type="pubmed-jr-id">20707</journal-id><journal-id journal-id-type="nlm-ta">Semin Cell Dev Biol</journal-id><journal-id journal-id-type="iso-abbrev">Semin. Cell Dev. Biol.</journal-id><journal-title-group><journal-title>Seminars in cell & developmental biology</journal-title></journal-title-group><issn pub-type="ppub">1084-9521</issn><issn pub-type="epub">1096-3634</issn></journal-meta><article-meta><article-id pub-id-type="pmid">24361867</article-id><article-id pub-id-type="pmc">3988237</article-id><article-id pub-id-type="doi">10.1016/j.semcdb.2013.12.006</article-id><article-id pub-id-type="manuscript">NIHMS550646</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>To grow or not to grow: Hair morphogenesis and human genetic hair disorders</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Duverger</surname><given-names>Olivier</given-names></name><xref ref-type="corresp" rid="CR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Morasso</surname><given-names>Maria I.</given-names></name><xref ref-type="corresp" rid="CR1">*</xref></contrib><aff id="A1">Laboratory of Skin Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20892, United States</aff></contrib-group><author-notes><corresp id="CR1"><label>*</label> Corresponding authors. Tel.: +1 3014357842; fax: +1 3014357910. <email>duvergero@mail.nih.gov</email> (O. Duverger), <email>morasso@nih.gov</email> (M.I. Morasso).</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>30</day><month>1</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>17</day><month>12</month><year>2013</year></pub-date><pub-date pub-type="ppub"><season>Jan-Feb</season><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>1</month><year>2015</year></pub-date><volume>0</volume><fpage>22</fpage><lpage>33</lpage><pmc-comment>elocation-id from pubmed: 10.1016/j.semcdb.2013.12.006</pmc-comment>
<abstract><p id="P1">Mouse models have greatly helped in elucidating the molecular mechanisms involved in hair formation and regeneration. Recent publications have reviewed the genes involved in mouse hair development based on the phenotype of transgenic, knockout and mutant animal models. While much of this information has been instrumental in determining molecular aspects of human hair development and cycling, mice exhibit a specific pattern of hair morphogenesis and hair distribution throughout the body that cannot be directly correlated to human hair. In this mini-review, we discuss specific aspects of human hair follicle development and present an up-to-date summary of human genetic disorders associated with abnormalities in hair follicle morphogenesis, structure or regeneration.</p></abstract><kwd-group><kwd>Hair follicle</kwd><kwd>Morphogenesis</kwd><kwd>Shaft differentiation</kwd><kwd>Genetic disorders</kwd><kwd>Alopecia</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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