THE 2011-2016 TRANSDISCIPLINARY RESEARCH IN ENERGETICS AND CANCER (TREC) INITIATIVE: RATIONALE AND DESIGN
Identifieur interne : 003890 ( Pmc/Curation ); précédent : 003889; suivant : 003891THE 2011-2016 TRANSDISCIPLINARY RESEARCH IN ENERGETICS AND CANCER (TREC) INITIATIVE: RATIONALE AND DESIGN
Auteurs : Ruth E. Patterson [États-Unis] ; Graham A. Colditz [États-Unis] ; Frank B. Hu [États-Unis] ; Kathryn H. Schmitz [États-Unis] ; Rexford S. Ahima [États-Unis] ; Ross C. Brownson [États-Unis] ; Kenneth R. Carson [États-Unis] ; Jorge E. Chavarro [États-Unis] ; Lewis A. Chodosh [États-Unis] ; Sarah Gehlert [États-Unis] ; Jeff Gill [États-Unis] ; Karen Glanz [États-Unis] ; Debra Haire-Joshu [États-Unis] ; Karen Louise Herbst [États-Unis] ; Christine M. Hoehner [États-Unis] ; Peter S. Hovmand [États-Unis] ; Melinda L. Irwin [États-Unis] ; Linda A. Jacobs [États-Unis] ; Aimee S. James [États-Unis] ; Lee W. Jones [États-Unis] ; Jacqueline Kerr [États-Unis] ; Adam S. Kibel [États-Unis] ; Irena B. King [États-Unis] ; Jennifer A. Ligibel [États-Unis] ; Jeffrey A. Meyerhardt [États-Unis] ; Loki Natarajan [États-Unis] ; Marian L. Neuhouser [États-Unis] ; Jerrold M. Olefsky [États-Unis] ; Enola K. Proctor [États-Unis] ; Susan Redline [États-Unis] ; Cheryl L. Rock [États-Unis] ; Bernard Rosner [États-Unis] ; David B. Sarwer [États-Unis] ; J. Sanford Schwartz [États-Unis] ; Dorothy D. Sears [États-Unis] ; Howard D. Sesso [États-Unis] ; Meir J. Stampfer [États-Unis] ; S. V. Subramanian [États-Unis] ; Elsie M. Taveras [États-Unis] ; Julia Tchou [États-Unis] ; Beti Thompson [États-Unis] ; Andrea B. Troxel [États-Unis] ; Marianne Wessling-Resnick [États-Unis] ; Kathleen Y. Wolin [États-Unis] ; Mark D. Thornquist [États-Unis]Source :
- Cancer causes & control : CCC [ 0957-5243 ] ; 2013.
Abstract
Recognition of the complex, multidimensional relationship between excess adiposity and cancer control outcomes has motivated the scientific community to seek new research models and paradigms.
The National Cancer Institute developed an innovative concept to establish a centers grant mechanism in nutrition, energetics, and physical activity; referred to as the Transdisciplinary Research on Energetics and Cancer (TREC) Initiative. This paper gives an overview of the 2011-2016 TREC Collaborative Network and the 15 research projects being conducted at the Centers.
Four academic institutions were awarded TREC center grants in 2011: Harvard University, University of California San Diego, University of Pennsylvania, and Washington University in St. Louis. The Fred Hutchinson Cancer Research Center is the Coordination Center. The TREC research portfolio includes 3 animal studies, 3 cohort studies, 4 randomized clinical trials, 1 cross-sectional study, and 2 modeling studies. Disciplines represented by TREC investigators include basic science, endocrinology, epidemiology, biostatistics, behavior, medicine, nutrition, physical activity, genetics, engineering, health economics, and computer science. Approximately 41,000 participants will be involved in these studies, including children, healthy adults, and breast and prostate cancer survivors. Outcomes include biomarkers of cancer risk, changes in weight and physical activity, persistent adverse treatment effects (e.g., lymphedema, urinary and sexual function), and breast and prostate cancer mortality.
The NIH Science of Team Science group will evaluate the value-added by this collaborative science. However, the most important outcome will be whether this transdisciplinary initiative improves the health of Americans at risk for cancer as well as cancer survivors.
Url:
DOI: 10.1007/s10552-013-0150-z
PubMed: 23378138
PubMed Central: 3602225
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Rock</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Rosner, Bernard" sort="Rosner, Bernard" uniqKey="Rosner B" first="Bernard" last="Rosner">Bernard Rosner</name><affiliation wicri:level="1"><nlm:aff id="A11"> Channing Laboratory, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Sarwer, David B" sort="Sarwer, David B" uniqKey="Sarwer D" first="David B." last="Sarwer">David B. Sarwer</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Schwartz, J Sanford" sort="Schwartz, J Sanford" uniqKey="Schwartz J" first="J. Sanford" last="Schwartz">J. Sanford Schwartz</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Sears, Dorothy D" sort="Sears, Dorothy D" uniqKey="Sears D" first="Dorothy D." last="Sears">Dorothy D. Sears</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name><affiliation wicri:level="1"><nlm:aff id="A10"> Brigham and Women's Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Brigham and Women's Hospital, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Stampfer, Meir J" sort="Stampfer, Meir J" uniqKey="Stampfer M" first="Meir J." last="Stampfer">Meir J. Stampfer</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Subramanian, S V" sort="Subramanian, S V" uniqKey="Subramanian S" first="S. V." last="Subramanian">S. V. Subramanian</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Taveras, Elsie M" sort="Taveras, Elsie M" uniqKey="Taveras E" first="Elsie M." last="Taveras">Elsie M. Taveras</name><affiliation wicri:level="1"><nlm:aff id="A12"> Harvard Pilgrim Health Care Institute, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard Pilgrim Health Care Institute, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Tchou, Julia" sort="Tchou, Julia" uniqKey="Tchou J" first="Julia" last="Tchou">Julia Tchou</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Thompson, Beti" sort="Thompson, Beti" uniqKey="Thompson B" first="Beti" last="Thompson">Beti Thompson</name><affiliation wicri:level="1"><nlm:aff id="A9"> Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea></affiliation></author><author><name sortKey="Troxel, Andrea B" sort="Troxel, Andrea B" uniqKey="Troxel A" first="Andrea B." last="Troxel">Andrea B. Troxel</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Wessling Resnick, Marianne" sort="Wessling Resnick, Marianne" uniqKey="Wessling Resnick M" first="Marianne" last="Wessling-Resnick">Marianne Wessling-Resnick</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Wolin, Kathleen Y" sort="Wolin, Kathleen Y" uniqKey="Wolin K" first="Kathleen Y." last="Wolin">Kathleen Y. Wolin</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Thornquist, Mark D" sort="Thornquist, Mark D" uniqKey="Thornquist M" first="Mark D." last="Thornquist">Mark D. Thornquist</name><affiliation wicri:level="1"><nlm:aff id="A9"> Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23378138</idno><idno type="pmc">3602225</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602225</idno><idno type="RBID">PMC:3602225</idno><idno type="doi">10.1007/s10552-013-0150-z</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">003891</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003891</idno><idno type="wicri:Area/Pmc/Curation">003890</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003890</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">THE 2011-2016 TRANSDISCIPLINARY RESEARCH IN ENERGETICS AND CANCER (TREC) INITIATIVE: RATIONALE AND DESIGN</title><author><name sortKey="Patterson, Ruth E" sort="Patterson, Ruth E" uniqKey="Patterson R" first="Ruth E." last="Patterson">Ruth E. Patterson</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Colditz, Graham A" sort="Colditz, Graham A" uniqKey="Colditz G" first="Graham A." last="Colditz">Graham A. Colditz</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Hu, Frank B" sort="Hu, Frank B" uniqKey="Hu F" first="Frank B." last="Hu">Frank B. Hu</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Schmitz, Kathryn H" sort="Schmitz, Kathryn H" uniqKey="Schmitz K" first="Kathryn H." last="Schmitz">Kathryn H. Schmitz</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Ahima, Rexford S" sort="Ahima, Rexford S" uniqKey="Ahima R" first="Rexford S." last="Ahima">Rexford S. Ahima</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Brownson, Ross C" sort="Brownson, Ross C" uniqKey="Brownson R" first="Ross C." last="Brownson">Ross C. Brownson</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Carson, Kenneth R" sort="Carson, Kenneth R" uniqKey="Carson K" first="Kenneth R." last="Carson">Kenneth R. Carson</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Chavarro, Jorge E" sort="Chavarro, Jorge E" uniqKey="Chavarro J" first="Jorge E." last="Chavarro">Jorge E. Chavarro</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Chodosh, Lewis A" sort="Chodosh, Lewis A" uniqKey="Chodosh L" first="Lewis A." last="Chodosh">Lewis A. Chodosh</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Gehlert, Sarah" sort="Gehlert, Sarah" uniqKey="Gehlert S" first="Sarah" last="Gehlert">Sarah Gehlert</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Gill, Jeff" sort="Gill, Jeff" uniqKey="Gill J" first="Jeff" last="Gill">Jeff Gill</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Glanz, Karen" sort="Glanz, Karen" uniqKey="Glanz K" first="Karen" last="Glanz">Karen Glanz</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Haire Joshu, Debra" sort="Haire Joshu, Debra" uniqKey="Haire Joshu D" first="Debra" last="Haire-Joshu">Debra Haire-Joshu</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Herbst, Karen Louise" sort="Herbst, Karen Louise" uniqKey="Herbst K" first="Karen Louise" last="Herbst">Karen Louise Herbst</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Hoehner, Christine M" sort="Hoehner, Christine M" uniqKey="Hoehner C" first="Christine M." last="Hoehner">Christine M. Hoehner</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Hovmand, Peter S" sort="Hovmand, Peter S" uniqKey="Hovmand P" first="Peter S." last="Hovmand">Peter S. Hovmand</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Irwin, Melinda L" sort="Irwin, Melinda L" uniqKey="Irwin M" first="Melinda L." last="Irwin">Melinda L. Irwin</name><affiliation wicri:level="1"><nlm:aff id="A5"> Yale University, New Haven, CT, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Yale University, New Haven, CT</wicri:regionArea></affiliation></author><author><name sortKey="Jacobs, Linda A" sort="Jacobs, Linda A" uniqKey="Jacobs L" first="Linda A." last="Jacobs">Linda A. Jacobs</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="James, Aimee S" sort="James, Aimee S" uniqKey="James A" first="Aimee S." last="James">Aimee S. James</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Jones, Lee W" sort="Jones, Lee W" uniqKey="Jones L" first="Lee W." last="Jones">Lee W. Jones</name><affiliation wicri:level="1"><nlm:aff id="A6"> Duke Cancer Institute, Durham NC, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Duke Cancer Institute, Durham NC</wicri:regionArea></affiliation></author><author><name sortKey="Kerr, Jacqueline" sort="Kerr, Jacqueline" uniqKey="Kerr J" first="Jacqueline" last="Kerr">Jacqueline Kerr</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Kibel, Adam S" sort="Kibel, Adam S" uniqKey="Kibel A" first="Adam S." last="Kibel">Adam S. Kibel</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="King, Irena B" sort="King, Irena B" uniqKey="King I" first="Irena B." last="King">Irena B. King</name><affiliation wicri:level="1"><nlm:aff id="A7"> University of New Mexico, Albuquerque, NM, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of New Mexico, Albuquerque, NM</wicri:regionArea></affiliation></author><author><name sortKey="Ligibel, Jennifer A" sort="Ligibel, Jennifer A" uniqKey="Ligibel J" first="Jennifer A." last="Ligibel">Jennifer A. Ligibel</name><affiliation wicri:level="2"><nlm:aff id="A8"> Dana-Farber Cancer Institute, Boston, MA USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Meyerhardt, Jeffrey A" sort="Meyerhardt, Jeffrey A" uniqKey="Meyerhardt J" first="Jeffrey A." last="Meyerhardt">Jeffrey A. Meyerhardt</name><affiliation wicri:level="2"><nlm:aff id="A8"> Dana-Farber Cancer Institute, Boston, MA USA</nlm:aff><country>États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Natarajan, Loki" sort="Natarajan, Loki" uniqKey="Natarajan L" first="Loki" last="Natarajan">Loki Natarajan</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Neuhouser, Marian L" sort="Neuhouser, Marian L" uniqKey="Neuhouser M" first="Marian L." last="Neuhouser">Marian L. Neuhouser</name><affiliation wicri:level="1"><nlm:aff id="A9"> Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea></affiliation></author><author><name sortKey="Olefsky, Jerrold M" sort="Olefsky, Jerrold M" uniqKey="Olefsky J" first="Jerrold M." last="Olefsky">Jerrold M. Olefsky</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Proctor, Enola K" sort="Proctor, Enola K" uniqKey="Proctor E" first="Enola K." last="Proctor">Enola K. Proctor</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Redline, Susan" sort="Redline, Susan" uniqKey="Redline S" first="Susan" last="Redline">Susan Redline</name><affiliation wicri:level="1"><nlm:aff id="A10"> Brigham and Women's Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Brigham and Women's Hospital, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Rock, Cheryl L" sort="Rock, Cheryl L" uniqKey="Rock C" first="Cheryl L." last="Rock">Cheryl L. Rock</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Rosner, Bernard" sort="Rosner, Bernard" uniqKey="Rosner B" first="Bernard" last="Rosner">Bernard Rosner</name><affiliation wicri:level="1"><nlm:aff id="A11"> Channing Laboratory, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Channing Laboratory, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Sarwer, David B" sort="Sarwer, David B" uniqKey="Sarwer D" first="David B." last="Sarwer">David B. Sarwer</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Schwartz, J Sanford" sort="Schwartz, J Sanford" uniqKey="Schwartz J" first="J. Sanford" last="Schwartz">J. Sanford Schwartz</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Sears, Dorothy D" sort="Sears, Dorothy D" uniqKey="Sears D" first="Dorothy D." last="Sears">Dorothy D. Sears</name><affiliation wicri:level="1"><nlm:aff id="A1"> University of California, San Diego, La Jolla, CA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of California, San Diego, La Jolla, CA</wicri:regionArea></affiliation></author><author><name sortKey="Sesso, Howard D" sort="Sesso, Howard D" uniqKey="Sesso H" first="Howard D." last="Sesso">Howard D. Sesso</name><affiliation wicri:level="1"><nlm:aff id="A10"> Brigham and Women's Hospital, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Brigham and Women's Hospital, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Stampfer, Meir J" sort="Stampfer, Meir J" uniqKey="Stampfer M" first="Meir J." last="Stampfer">Meir J. Stampfer</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Subramanian, S V" sort="Subramanian, S V" uniqKey="Subramanian S" first="S. V." last="Subramanian">S. V. Subramanian</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Taveras, Elsie M" sort="Taveras, Elsie M" uniqKey="Taveras E" first="Elsie M." last="Taveras">Elsie M. Taveras</name><affiliation wicri:level="1"><nlm:aff id="A12"> Harvard Pilgrim Health Care Institute, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard Pilgrim Health Care Institute, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Tchou, Julia" sort="Tchou, Julia" uniqKey="Tchou J" first="Julia" last="Tchou">Julia Tchou</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Thompson, Beti" sort="Thompson, Beti" uniqKey="Thompson B" first="Beti" last="Thompson">Beti Thompson</name><affiliation wicri:level="1"><nlm:aff id="A9"> Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea></affiliation></author><author><name sortKey="Troxel, Andrea B" sort="Troxel, Andrea B" uniqKey="Troxel A" first="Andrea B." last="Troxel">Andrea B. Troxel</name><affiliation wicri:level="1"><nlm:aff id="A4"> University of Pennsylvania, Philadelphia, PA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> University of Pennsylvania, Philadelphia, PA</wicri:regionArea></affiliation></author><author><name sortKey="Wessling Resnick, Marianne" sort="Wessling Resnick, Marianne" uniqKey="Wessling Resnick M" first="Marianne" last="Wessling-Resnick">Marianne Wessling-Resnick</name><affiliation wicri:level="1"><nlm:aff id="A3"> Harvard University, Boston, MA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Harvard University, Boston, MA</wicri:regionArea></affiliation></author><author><name sortKey="Wolin, Kathleen Y" sort="Wolin, Kathleen Y" uniqKey="Wolin K" first="Kathleen Y." last="Wolin">Kathleen Y. Wolin</name><affiliation wicri:level="1"><nlm:aff id="A2"> Washington University in St. Louis, St. Louis, MO, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Washington University in St. Louis, St. Louis, MO</wicri:regionArea></affiliation></author><author><name sortKey="Thornquist, Mark D" sort="Thornquist, Mark D" uniqKey="Thornquist M" first="Mark D." last="Thornquist">Mark D. Thornquist</name><affiliation wicri:level="1"><nlm:aff id="A9"> Fred Hutchinson Cancer Research Center, Seattle, WA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Fred Hutchinson Cancer Research Center, Seattle, WA</wicri:regionArea></affiliation></author></analytic><series><title level="j">Cancer causes & control : CCC</title><idno type="ISSN">0957-5243</idno><idno type="eISSN">1573-7225</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Purpose</title><p id="P1">Recognition of the complex, multidimensional relationship between excess adiposity and cancer control outcomes has motivated the scientific community to seek new research models and paradigms.</p></sec><sec id="S2"><title>Methods</title><p id="P2">The National Cancer Institute developed an innovative concept to establish a centers grant mechanism in nutrition, energetics, and physical activity; referred to as the Transdisciplinary Research on Energetics and Cancer (TREC) Initiative. This paper gives an overview of the 2011-2016 TREC Collaborative Network and the 15 research projects being conducted at the Centers.</p></sec><sec id="S3"><title>Results</title><p id="P3">Four academic institutions were awarded TREC center grants in 2011: Harvard University, University of California San Diego, University of Pennsylvania, and Washington University in St. Louis. The Fred Hutchinson Cancer Research Center is the Coordination Center. The TREC research portfolio includes 3 animal studies, 3 cohort studies, 4 randomized clinical trials, 1 cross-sectional study, and 2 modeling studies. Disciplines represented by TREC investigators include basic science, endocrinology, epidemiology, biostatistics, behavior, medicine, nutrition, physical activity, genetics, engineering, health economics, and computer science. Approximately 41,000 participants will be involved in these studies, including children, healthy adults, and breast and prostate cancer survivors. Outcomes include biomarkers of cancer risk, changes in weight and physical activity, persistent adverse treatment effects (e.g., lymphedema, urinary and sexual function), and breast and prostate cancer mortality.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">The NIH Science of Team Science group will evaluate the value-added by this collaborative science. However, the most important outcome will be whether this transdisciplinary initiative improves the health of Americans at risk for cancer as well as cancer survivors.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9100846</journal-id><journal-id journal-id-type="pubmed-jr-id">1173</journal-id><journal-id journal-id-type="nlm-ta">Cancer Causes Control</journal-id><journal-id journal-id-type="iso-abbrev">Cancer Causes Control</journal-id><journal-title-group><journal-title>Cancer causes & control : CCC</journal-title></journal-title-group><issn pub-type="ppub">0957-5243</issn><issn pub-type="epub">1573-7225</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23378138</article-id><article-id pub-id-type="pmc">3602225</article-id><article-id pub-id-type="doi">10.1007/s10552-013-0150-z</article-id><article-id pub-id-type="manuscript">NIHMS441823</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>THE 2011-2016 TRANSDISCIPLINARY RESEARCH IN ENERGETICS AND CANCER (TREC) INITIATIVE: RATIONALE AND DESIGN</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Patterson</surname><given-names>Ruth E.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Colditz</surname><given-names>Graham A.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Hu</surname><given-names>Frank B.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Schmitz</surname><given-names>Kathryn H.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Ahima</surname><given-names>Rexford S.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Brownson</surname><given-names>Ross C.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Carson</surname><given-names>Kenneth R.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Chavarro</surname><given-names>Jorge E.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Chodosh</surname><given-names>Lewis A.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Gehlert</surname><given-names>Sarah</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Gill</surname><given-names>Jeff</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Glanz</surname><given-names>Karen</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Haire-Joshu</surname><given-names>Debra</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Herbst</surname><given-names>Karen Louise</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Hoehner</surname><given-names>Christine M.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Hovmand</surname><given-names>Peter S.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Irwin</surname><given-names>Melinda L.</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Jacobs</surname><given-names>Linda A.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>James</surname><given-names>Aimee S.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Jones</surname><given-names>Lee W.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Kerr</surname><given-names>Jacqueline</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Kibel</surname><given-names>Adam S.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>King</surname><given-names>Irena B.</given-names></name><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Ligibel</surname><given-names>Jennifer A.</given-names></name><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Meyerhardt</surname><given-names>Jeffrey A.</given-names></name><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Natarajan</surname><given-names>Loki</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Neuhouser</surname><given-names>Marian L.</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Olefsky</surname><given-names>Jerrold M.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Proctor</surname><given-names>Enola K.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Redline</surname><given-names>Susan</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Rock</surname><given-names>Cheryl L.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Rosner</surname><given-names>Bernard</given-names></name><xref ref-type="aff" rid="A11">11</xref></contrib><contrib contrib-type="author"><name><surname>Sarwer</surname><given-names>David B.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Schwartz</surname><given-names>J. Sanford</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Sears</surname><given-names>Dorothy D.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Sesso</surname><given-names>Howard D.</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Stampfer</surname><given-names>Meir J.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Subramanian</surname><given-names>S. V.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Taveras</surname><given-names>Elsie M.</given-names></name><xref ref-type="aff" rid="A12">12</xref></contrib><contrib contrib-type="author"><name><surname>Tchou</surname><given-names>Julia</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Thompson</surname><given-names>Beti</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Troxel</surname><given-names>Andrea B.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Wessling-Resnick</surname><given-names>Marianne</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Wolin</surname><given-names>Kathleen Y.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Thornquist</surname><given-names>Mark D.</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib></contrib-group><aff id="A1"><label>1</label> University of California, San Diego, La Jolla, CA, USA</aff><aff id="A2"><label>2</label> Washington University in St. Louis, St. Louis, MO, USA</aff><aff id="A3"><label>3</label> Harvard University, Boston, MA, USA</aff><aff id="A4"><label>4</label> University of Pennsylvania, Philadelphia, PA, USA</aff><aff id="A5"><label>5</label> Yale University, New Haven, CT, USA</aff><aff id="A6"><label>6</label> Duke Cancer Institute, Durham NC, USA</aff><aff id="A7"><label>7</label> University of New Mexico, Albuquerque, NM, USA</aff><aff id="A8"><label>8</label> Dana-Farber Cancer Institute, Boston, MA USA</aff><aff id="A9"><label>9</label> Fred Hutchinson Cancer Research Center, Seattle, WA, USA</aff><aff id="A10"><label>10</label> Brigham and Women's Hospital, Boston, MA, USA</aff><aff id="A11"><label>11</label> Channing Laboratory, Boston, MA, USA</aff><aff id="A12"><label>12</label> Harvard Pilgrim Health Care Institute, Boston, MA, USA</aff><author-notes><corresp id="CR1">Corresponding author: Mark D. Thornquist, <email>mthornqu@fhcrc.org</email>, phone: 206-667-2931, fax: 206-667-5964</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>7</day><month>2</month><year>2013</year></pub-date><pub-date pub-type="epub"><day>03</day><month>2</month><year>2013</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>4</month><year>2014</year></pub-date><volume>24</volume><issue>4</issue><fpage>695</fpage><lpage>704</lpage><abstract><sec id="S1"><title>Purpose</title><p id="P1">Recognition of the complex, multidimensional relationship between excess adiposity and cancer control outcomes has motivated the scientific community to seek new research models and paradigms.</p></sec><sec id="S2"><title>Methods</title><p id="P2">The National Cancer Institute developed an innovative concept to establish a centers grant mechanism in nutrition, energetics, and physical activity; referred to as the Transdisciplinary Research on Energetics and Cancer (TREC) Initiative. This paper gives an overview of the 2011-2016 TREC Collaborative Network and the 15 research projects being conducted at the Centers.</p></sec><sec id="S3"><title>Results</title><p id="P3">Four academic institutions were awarded TREC center grants in 2011: Harvard University, University of California San Diego, University of Pennsylvania, and Washington University in St. Louis. The Fred Hutchinson Cancer Research Center is the Coordination Center. The TREC research portfolio includes 3 animal studies, 3 cohort studies, 4 randomized clinical trials, 1 cross-sectional study, and 2 modeling studies. Disciplines represented by TREC investigators include basic science, endocrinology, epidemiology, biostatistics, behavior, medicine, nutrition, physical activity, genetics, engineering, health economics, and computer science. Approximately 41,000 participants will be involved in these studies, including children, healthy adults, and breast and prostate cancer survivors. Outcomes include biomarkers of cancer risk, changes in weight and physical activity, persistent adverse treatment effects (e.g., lymphedema, urinary and sexual function), and breast and prostate cancer mortality.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">The NIH Science of Team Science group will evaluate the value-added by this collaborative science. However, the most important outcome will be whether this transdisciplinary initiative improves the health of Americans at risk for cancer as well as cancer survivors.</p></sec></abstract><kwd-group><kwd>energetics</kwd><kwd>obesity</kwd><kwd>diet</kwd><kwd>physical activity</kwd><kwd>cancer</kwd><kwd>transdisciplinary</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U54 CA155850 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U54 CA155626 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U54 CA155496 || CA</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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