Weight Lifting and Appendicular Skeletal Muscle Mass among Breast Cancer Survivors: A Randomized Controlled Trial
Identifieur interne : 003763 ( Pmc/Curation ); précédent : 003762; suivant : 003764Weight Lifting and Appendicular Skeletal Muscle Mass among Breast Cancer Survivors: A Randomized Controlled Trial
Auteurs : Justin C. Brown ; Kathryn H. SchmitzSource :
- Breast cancer research and treatment [ 0167-6806 ] ; 2015.
Abstract
Low appendicular skeletal muscle mass (ASMM) is associated with premature mortality, hyperinsulinemia, frailty, disability, and low bone mineral density. We explored the potential efficacy of slowly-progressive weight lifting to attenuate the decline of ASMM among breast cancer survivors by conducting a post hoc analysis of data from the Physical Activity and Lymphedema trial.
Between October 2005 and August 2008 we conducted a single-blind, randomized controlled trial of twice-weekly slowly-progressive weight lifting or standard care among 295 non-metastatic breast cancer survivors. ASMM was quantified using dual-energy x-ray absorptiometry. Changes in ASMM were evaluated from baseline to 12-months between the weight lifting and control groups using repeated-measures linear mixed-effects regression models.
Over 12-months, participants in the weight lifting group experienced attenuated declines in muscle mass compared to the control group, as reflected by relative ASMM (−0.01±0.02 kg/m2 versus −0.08±0.03 kg/m2;
Slowly-progressive weight lifting attenuated the decline of ASMM among breast cancer survivors compared to standard care over 12-months. These data are hypothesis generating. Future studies should examine the efficacy of weight lifting to improve distal health outcomes among breast cancer survivors.
Url:
DOI: 10.1007/s10549-015-3409-0
PubMed: 25935584
PubMed Central: 4596259
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :003764
Links to Exploration step
PMC:4596259Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Weight Lifting and Appendicular Skeletal Muscle Mass among Breast Cancer Survivors: A Randomized Controlled Trial</title>
<author><name sortKey="Brown, Justin C" sort="Brown, Justin C" uniqKey="Brown J" first="Justin C." last="Brown">Justin C. Brown</name>
</author>
<author><name sortKey="Schmitz, Kathryn H" sort="Schmitz, Kathryn H" uniqKey="Schmitz K" first="Kathryn H." last="Schmitz">Kathryn H. Schmitz</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25935584</idno>
<idno type="pmc">4596259</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596259</idno>
<idno type="RBID">PMC:4596259</idno>
<idno type="doi">10.1007/s10549-015-3409-0</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">003764</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003764</idno>
<idno type="wicri:Area/Pmc/Curation">003763</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">003763</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Weight Lifting and Appendicular Skeletal Muscle Mass among Breast Cancer Survivors: A Randomized Controlled Trial</title>
<author><name sortKey="Brown, Justin C" sort="Brown, Justin C" uniqKey="Brown J" first="Justin C." last="Brown">Justin C. Brown</name>
</author>
<author><name sortKey="Schmitz, Kathryn H" sort="Schmitz, Kathryn H" uniqKey="Schmitz K" first="Kathryn H." last="Schmitz">Kathryn H. Schmitz</name>
</author>
</analytic>
<series><title level="j">Breast cancer research and treatment</title>
<idno type="ISSN">0167-6806</idno>
<idno type="eISSN">1573-7217</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Purpose</title>
<p id="P1">Low appendicular skeletal muscle mass (ASMM) is associated with premature mortality, hyperinsulinemia, frailty, disability, and low bone mineral density. We explored the potential efficacy of slowly-progressive weight lifting to attenuate the decline of ASMM among breast cancer survivors by conducting a post hoc analysis of data from the Physical Activity and Lymphedema trial.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Between October 2005 and August 2008 we conducted a single-blind, randomized controlled trial of twice-weekly slowly-progressive weight lifting or standard care among 295 non-metastatic breast cancer survivors. ASMM was quantified using dual-energy x-ray absorptiometry. Changes in ASMM were evaluated from baseline to 12-months between the weight lifting and control groups using repeated-measures linear mixed-effects regression models.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Over 12-months, participants in the weight lifting group experienced attenuated declines in muscle mass compared to the control group, as reflected by relative ASMM (−0.01±0.02 kg/m<sup>2</sup>
versus −0.08±0.03 kg/m<sup>2</sup>
; <italic>P</italic>
=0.041) and absolute ASMM (−0.02±0.06 kg versus −0.22±0.07 kg; <italic>P</italic>
=0.038), respectively. Weight lifting did not alter other body composition outcomes including body mass index, total body mass, body fat percentage, and fat mass compared to the control group. Weight lifting significantly increased upper- and lower-body muscle strength compared to the control group. The intervention was well-tolerated with no serious adverse events related to weight lifting.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Slowly-progressive weight lifting attenuated the decline of ASMM among breast cancer survivors compared to standard care over 12-months. These data are hypothesis generating. Future studies should examine the efficacy of weight lifting to improve distal health outcomes among breast cancer survivors.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8111104</journal-id>
<journal-id journal-id-type="pubmed-jr-id">1254</journal-id>
<journal-id journal-id-type="nlm-ta">Breast Cancer Res Treat</journal-id>
<journal-id journal-id-type="iso-abbrev">Breast Cancer Res. Treat.</journal-id>
<journal-title-group><journal-title>Breast cancer research and treatment</journal-title>
</journal-title-group>
<issn pub-type="ppub">0167-6806</issn>
<issn pub-type="epub">1573-7217</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">25935584</article-id>
<article-id pub-id-type="pmc">4596259</article-id>
<article-id pub-id-type="doi">10.1007/s10549-015-3409-0</article-id>
<article-id pub-id-type="manuscript">NIHMS725651</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Weight Lifting and Appendicular Skeletal Muscle Mass among Breast Cancer Survivors: A Randomized Controlled Trial</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Brown</surname>
<given-names>Justin C.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Schmitz</surname>
<given-names>Kathryn H.</given-names>
</name>
</contrib>
<aff id="A1">Center or Clinical Epidemiology & Biostatistics, Perelman School of Medicine, University of Pennsylvania</aff>
</contrib-group>
<author-notes><corresp id="cor1">Corresponding Author: Kathryn H. Schmitz, University of Pennsylvania School of Medicine, 423 Guardian Drive, 8th Floor, Blockley Hall, Philadelphia, PA 19104, Phone: 215–898–6604, Fax: 251–573–5311, <email>schmitz@mail.med.upenn.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>28</day>
<month>9</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub"><day>03</day>
<month>5</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="ppub"><month>6</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>07</day>
<month>10</month>
<year>2015</year>
</pub-date>
<volume>151</volume>
<issue>2</issue>
<fpage>385</fpage>
<lpage>392</lpage>
<pmc-comment>elocation-id from pubmed: 10.1007/s10549-015-3409-0</pmc-comment>
<abstract><sec id="S1"><title>Purpose</title>
<p id="P1">Low appendicular skeletal muscle mass (ASMM) is associated with premature mortality, hyperinsulinemia, frailty, disability, and low bone mineral density. We explored the potential efficacy of slowly-progressive weight lifting to attenuate the decline of ASMM among breast cancer survivors by conducting a post hoc analysis of data from the Physical Activity and Lymphedema trial.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Between October 2005 and August 2008 we conducted a single-blind, randomized controlled trial of twice-weekly slowly-progressive weight lifting or standard care among 295 non-metastatic breast cancer survivors. ASMM was quantified using dual-energy x-ray absorptiometry. Changes in ASMM were evaluated from baseline to 12-months between the weight lifting and control groups using repeated-measures linear mixed-effects regression models.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Over 12-months, participants in the weight lifting group experienced attenuated declines in muscle mass compared to the control group, as reflected by relative ASMM (−0.01±0.02 kg/m<sup>2</sup>
versus −0.08±0.03 kg/m<sup>2</sup>
; <italic>P</italic>
=0.041) and absolute ASMM (−0.02±0.06 kg versus −0.22±0.07 kg; <italic>P</italic>
=0.038), respectively. Weight lifting did not alter other body composition outcomes including body mass index, total body mass, body fat percentage, and fat mass compared to the control group. Weight lifting significantly increased upper- and lower-body muscle strength compared to the control group. The intervention was well-tolerated with no serious adverse events related to weight lifting.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Slowly-progressive weight lifting attenuated the decline of ASMM among breast cancer survivors compared to standard care over 12-months. These data are hypothesis generating. Future studies should examine the efficacy of weight lifting to improve distal health outcomes among breast cancer survivors.</p>
</sec>
</abstract>
<kwd-group><kwd>muscle</kwd>
<kwd>exercise</kwd>
<kwd>physical activity</kwd>
<kwd>strength training</kwd>
<kwd>aging</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003763 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 003763 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Pmc |étape= Curation |type= RBID |clé= PMC:4596259 |texte= Weight Lifting and Appendicular Skeletal Muscle Mass among Breast Cancer Survivors: A Randomized Controlled Trial }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:25935584" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \ | NlmPubMed2Wicri -a LymphedemaV1
This area was generated with Dilib version V0.6.31. |