RTOG Sarcoma Radiation Oncologists Reach Consensus on Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) on Computed Tomographic Images for Preoperative Radiotherapy of Primary Soft Tissue Sarcoma of Extremity in RTOG Studies
Identifieur interne : 002A04 ( Pmc/Curation ); précédent : 002A03; suivant : 002A05RTOG Sarcoma Radiation Oncologists Reach Consensus on Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) on Computed Tomographic Images for Preoperative Radiotherapy of Primary Soft Tissue Sarcoma of Extremity in RTOG Studies
Auteurs : Dian Wang [États-Unis] ; Walter Bosch [États-Unis] ; David Roberge [Canada] ; Steven E. Finkelstein [États-Unis] ; Ivy Petersen [États-Unis] ; Michael Haddock [États-Unis] ; Yen-Lin E. Chen [États-Unis] ; Naoyuki G. Saito [États-Unis] ; David G. Kirsch [États-Unis] ; Ying J. Hitchcock [États-Unis] ; Aaron H. Wolfson ; Thomas F. Delaney [États-Unis]Source :
- International journal of radiation oncology, biology, physics [ 0360-3016 ] ; 2011.
Abstract
To develop an Radiation Therapy Oncology Group (RTOG) atlas delineating gross tumor volume (GTV), and clinical target volume (CTV) to be used for preoperative radiotherapy of primary extremity soft tissue sarcoma (STS).
A consensus meeting was held during the RTOG meeting in January 2010 to reach agreement about GTV and CTV delineation on CT images for preoperative radiotherapy of high-grade large extremity STS. Data were presented to address the local extension of STS. Extensive discussion ensued to develop optimal criteria for GTV and CTV delineation on CT images.
A consensus was reached on appropriate CT-based GTV and CTV. GTV is gross tumor defined by T1 contrast-enhanced MRI images. Fusion of MRI and CT is recommended to delineate the GTV. CTV for high-grade large STS typically includes GTV plus 3 cm margins in the longitudinal directions. If this causes the field to extend beyond the compartment, the field can be shortened to include the end of a compartment. The radial margin from the lesion should be 1.5 cm including any portion of the tumor not confined by an intact fascial barrier, bone or skin surface.
The consensus on GTV and CTV for preoperative radiotherapy of high-grade large extremity STS is available as web-based images as well as descriptive format through the RTOG. This is expected to improve target volume consistency and allow for rigorous evaluation of the benefits and risks of such treatment.
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DOI: 10.1016/j.ijrobp.2011.04.038
PubMed: 21676552
PubMed Central: 3205346
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">RTOG Sarcoma Radiation Oncologists Reach Consensus on Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) on Computed Tomographic Images for Preoperative Radiotherapy of Primary Soft Tissue Sarcoma of Extremity in RTOG Studies</title><author><name sortKey="Wang, Dian" sort="Wang, Dian" uniqKey="Wang D" first="Dian" last="Wang">Dian Wang</name><affiliation wicri:level="2"><nlm:aff id="A1">Medical College of Wisconsin, Milwaukee, WI</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Wisconsin</region></placeName><wicri:cityArea>Medical College of Wisconsin, Milwaukee</wicri:cityArea></affiliation></author><author><name sortKey="Bosch, Walter" sort="Bosch, Walter" uniqKey="Bosch W" first="Walter" last="Bosch">Walter Bosch</name><affiliation wicri:level="2"><nlm:aff id="A2">Washington University , St Louis, MO</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Washington University , St Louis</wicri:cityArea></affiliation></author><author><name sortKey="Roberge, David" sort="Roberge, David" uniqKey="Roberge D" first="David" last="Roberge">David Roberge</name><affiliation wicri:level="1"><nlm:aff id="A3">McGill University, Montreal, QC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>McGill University, Montreal, QC</wicri:regionArea></affiliation></author><author><name sortKey="Finkelstein, Steven E" sort="Finkelstein, Steven E" uniqKey="Finkelstein S" first="Steven E." last="Finkelstein">Steven E. Finkelstein</name><affiliation wicri:level="2"><nlm:aff id="A5">Moffitt Cancer Center, Tampa, FL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Moffitt Cancer Center, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Petersen, Ivy" sort="Petersen, Ivy" uniqKey="Petersen I" first="Ivy" last="Petersen">Ivy Petersen</name><affiliation wicri:level="2"><nlm:aff id="A4">Mayo Clinic, Rochester, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Haddock, Michael" sort="Haddock, Michael" uniqKey="Haddock M" first="Michael" last="Haddock">Michael Haddock</name><affiliation wicri:level="2"><nlm:aff id="A4">Mayo Clinic, Rochester, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Chen, Yen Lin E" sort="Chen, Yen Lin E" uniqKey="Chen Y" first="Yen-Lin E." last="Chen">Yen-Lin E. Chen</name><affiliation wicri:level="2"><nlm:aff id="A6">Massachusetts General Hospital, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Saito, Naoyuki G" sort="Saito, Naoyuki G" uniqKey="Saito N" first="Naoyuki G." last="Saito">Naoyuki G. Saito</name><affiliation wicri:level="2"><nlm:aff id="A7">Roswell Park Cancer Institute, Buffalo, NY</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Roswell Park Cancer Institute, Buffalo</wicri:cityArea></affiliation></author><author><name sortKey="Kirsch, David G" sort="Kirsch, David G" uniqKey="Kirsch D" first="David G." last="Kirsch">David G. Kirsch</name><affiliation wicri:level="2"><nlm:aff id="A8">Duke University, Durham, NC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Hitchcock, Ying J" sort="Hitchcock, Ying J" uniqKey="Hitchcock Y" first="Ying J." last="Hitchcock">Ying J. Hitchcock</name><affiliation wicri:level="2"><nlm:aff id="A9">University of Utah, Salt Lake City, UT</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>University of Utah, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Wolfson, Aaron H" sort="Wolfson, Aaron H" uniqKey="Wolfson A" first="Aaron H." last="Wolfson">Aaron H. Wolfson</name><affiliation><nlm:aff id="A10">University of Miami Miller School of Medicine, Miami, FL.</nlm:aff><wicri:noCountry code="subfield">FL.</wicri:noCountry></affiliation></author><author><name sortKey="Delaney, Thomas F" sort="Delaney, Thomas F" uniqKey="Delaney T" first="Thomas F." last="Delaney">Thomas F. Delaney</name><affiliation wicri:level="2"><nlm:aff id="A6">Massachusetts General Hospital, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21676552</idno><idno type="pmc">3205346</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205346</idno><idno type="RBID">PMC:3205346</idno><idno type="doi">10.1016/j.ijrobp.2011.04.038</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">002A05</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002A05</idno><idno type="wicri:Area/Pmc/Curation">002A04</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002A04</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">RTOG Sarcoma Radiation Oncologists Reach Consensus on Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) on Computed Tomographic Images for Preoperative Radiotherapy of Primary Soft Tissue Sarcoma of Extremity in RTOG Studies</title><author><name sortKey="Wang, Dian" sort="Wang, Dian" uniqKey="Wang D" first="Dian" last="Wang">Dian Wang</name><affiliation wicri:level="2"><nlm:aff id="A1">Medical College of Wisconsin, Milwaukee, WI</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Wisconsin</region></placeName><wicri:cityArea>Medical College of Wisconsin, Milwaukee</wicri:cityArea></affiliation></author><author><name sortKey="Bosch, Walter" sort="Bosch, Walter" uniqKey="Bosch W" first="Walter" last="Bosch">Walter Bosch</name><affiliation wicri:level="2"><nlm:aff id="A2">Washington University , St Louis, MO</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Missouri (État)</region></placeName><wicri:cityArea>Washington University , St Louis</wicri:cityArea></affiliation></author><author><name sortKey="Roberge, David" sort="Roberge, David" uniqKey="Roberge D" first="David" last="Roberge">David Roberge</name><affiliation wicri:level="1"><nlm:aff id="A3">McGill University, Montreal, QC, Canada</nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea>McGill University, Montreal, QC</wicri:regionArea></affiliation></author><author><name sortKey="Finkelstein, Steven E" sort="Finkelstein, Steven E" uniqKey="Finkelstein S" first="Steven E." last="Finkelstein">Steven E. Finkelstein</name><affiliation wicri:level="2"><nlm:aff id="A5">Moffitt Cancer Center, Tampa, FL</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Moffitt Cancer Center, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Petersen, Ivy" sort="Petersen, Ivy" uniqKey="Petersen I" first="Ivy" last="Petersen">Ivy Petersen</name><affiliation wicri:level="2"><nlm:aff id="A4">Mayo Clinic, Rochester, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Haddock, Michael" sort="Haddock, Michael" uniqKey="Haddock M" first="Michael" last="Haddock">Michael Haddock</name><affiliation wicri:level="2"><nlm:aff id="A4">Mayo Clinic, Rochester, MN</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Minnesota</region></placeName><wicri:cityArea>Mayo Clinic, Rochester</wicri:cityArea></affiliation></author><author><name sortKey="Chen, Yen Lin E" sort="Chen, Yen Lin E" uniqKey="Chen Y" first="Yen-Lin E." last="Chen">Yen-Lin E. Chen</name><affiliation wicri:level="2"><nlm:aff id="A6">Massachusetts General Hospital, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Saito, Naoyuki G" sort="Saito, Naoyuki G" uniqKey="Saito N" first="Naoyuki G." last="Saito">Naoyuki G. Saito</name><affiliation wicri:level="2"><nlm:aff id="A7">Roswell Park Cancer Institute, Buffalo, NY</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Roswell Park Cancer Institute, Buffalo</wicri:cityArea></affiliation></author><author><name sortKey="Kirsch, David G" sort="Kirsch, David G" uniqKey="Kirsch D" first="David G." last="Kirsch">David G. Kirsch</name><affiliation wicri:level="2"><nlm:aff id="A8">Duke University, Durham, NC</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Caroline du Nord</region></placeName><wicri:cityArea>Duke University, Durham</wicri:cityArea></affiliation></author><author><name sortKey="Hitchcock, Ying J" sort="Hitchcock, Ying J" uniqKey="Hitchcock Y" first="Ying J." last="Hitchcock">Ying J. Hitchcock</name><affiliation wicri:level="2"><nlm:aff id="A9">University of Utah, Salt Lake City, UT</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Utah</region></placeName><wicri:cityArea>University of Utah, Salt Lake City</wicri:cityArea></affiliation></author><author><name sortKey="Wolfson, Aaron H" sort="Wolfson, Aaron H" uniqKey="Wolfson A" first="Aaron H." last="Wolfson">Aaron H. Wolfson</name><affiliation><nlm:aff id="A10">University of Miami Miller School of Medicine, Miami, FL.</nlm:aff><wicri:noCountry code="subfield">FL.</wicri:noCountry></affiliation></author><author><name sortKey="Delaney, Thomas F" sort="Delaney, Thomas F" uniqKey="Delaney T" first="Thomas F." last="Delaney">Thomas F. Delaney</name><affiliation wicri:level="2"><nlm:aff id="A6">Massachusetts General Hospital, Boston, MA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author></analytic><series><title level="j">International journal of radiation oncology, biology, physics</title><idno type="ISSN">0360-3016</idno><idno type="eISSN">1879-355X</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">To develop an Radiation Therapy Oncology Group (RTOG) atlas delineating gross tumor volume (GTV), and clinical target volume (CTV) to be used for preoperative radiotherapy of primary extremity soft tissue sarcoma (STS).</p></sec><sec sec-type="methods" id="S2"><title>Methods</title><p id="P2">A consensus meeting was held during the RTOG meeting in January 2010 to reach agreement about GTV and CTV delineation on CT images for preoperative radiotherapy of high-grade large extremity STS. Data were presented to address the local extension of STS. Extensive discussion ensued to develop optimal criteria for GTV and CTV delineation on CT images.</p></sec><sec id="S3"><title>Results</title><p id="P3">A consensus was reached on appropriate CT-based GTV and CTV. GTV is gross tumor defined by T1 contrast-enhanced MRI images. Fusion of MRI and CT is recommended to delineate the GTV. CTV for high-grade large STS typically includes GTV plus 3 cm margins in the longitudinal directions. If this causes the field to extend beyond the compartment, the field can be shortened to include the end of a compartment. The radial margin from the lesion should be 1.5 cm including any portion of the tumor not confined by an intact fascial barrier, bone or skin surface.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">The consensus on GTV and CTV for preoperative radiotherapy of high-grade large extremity STS is available as web-based images as well as descriptive format through the RTOG. This is expected to improve target volume consistency and allow for rigorous evaluation of the benefits and risks of such treatment.</p></sec></div></front></TEI><pmc article-type="research-article" xml:lang="en"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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<front><journal-meta><journal-id journal-id-type="nlm-journal-id">7603616</journal-id><journal-id journal-id-type="pubmed-jr-id">4036</journal-id><journal-id journal-id-type="nlm-ta">Int J Radiat Oncol Biol Phys</journal-id><journal-title-group><journal-title>International journal of radiation oncology, biology, physics</journal-title></journal-title-group><issn pub-type="ppub">0360-3016</issn><issn pub-type="epub">1879-355X</issn></journal-meta><article-meta><article-id pub-id-type="pmid">21676552</article-id><article-id pub-id-type="pmc">3205346</article-id><article-id pub-id-type="doi">10.1016/j.ijrobp.2011.04.038</article-id><article-id pub-id-type="manuscript">NIHMS305924</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>RTOG Sarcoma Radiation Oncologists Reach Consensus on Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) on Computed Tomographic Images for Preoperative Radiotherapy of Primary Soft Tissue Sarcoma of Extremity in RTOG Studies</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Dian</given-names></name><xref ref-type="aff" rid="A1">*</xref></contrib><contrib contrib-type="author"><name><surname>Bosch</surname><given-names>Walter</given-names></name><xref ref-type="aff" rid="A2">†</xref></contrib><contrib contrib-type="author"><name><surname>Roberge</surname><given-names>David</given-names></name><xref ref-type="aff" rid="A3">§</xref></contrib><contrib contrib-type="author"><name><surname>Finkelstein</surname><given-names>Steven E.</given-names></name><xref ref-type="aff" rid="A5">¶</xref></contrib><contrib contrib-type="author"><name><surname>Petersen</surname><given-names>Ivy</given-names></name><xref ref-type="aff" rid="A4">§§</xref></contrib><contrib contrib-type="author"><name><surname>Haddock</surname><given-names>Michael</given-names></name><xref ref-type="aff" rid="A4">§§</xref></contrib><contrib contrib-type="author"><name><surname>Chen</surname><given-names>Yen-Lin E.</given-names></name><xref ref-type="aff" rid="A6">**</xref></contrib><contrib contrib-type="author"><name><surname>Saito</surname><given-names>Naoyuki G.</given-names></name><xref ref-type="aff" rid="A7">††</xref></contrib><contrib contrib-type="author"><name><surname>Kirsch</surname><given-names>David G.</given-names></name><xref ref-type="aff" rid="A8">‡</xref></contrib><contrib contrib-type="author"><name><surname>Hitchcock</surname><given-names>Ying J.</given-names></name><xref ref-type="aff" rid="A9">‡‡</xref></contrib><contrib contrib-type="author"><name><surname>Wolfson</surname><given-names>Aaron H.</given-names></name><xref ref-type="aff" rid="A10">¶¶</xref></contrib><contrib contrib-type="author"><name><surname>DeLaney</surname><given-names>Thomas F.</given-names></name><xref ref-type="aff" rid="A6">**</xref></contrib></contrib-group><aff id="A1"><label>*</label>Medical College of Wisconsin, Milwaukee, WI</aff><aff id="A2"><label>†</label>Washington University , St Louis, MO</aff><aff id="A3"><label>§</label>McGill University, Montreal, QC, Canada</aff><aff id="A4"><label>§§</label>Mayo Clinic, Rochester, MN</aff><aff id="A5"><label>¶</label>Moffitt Cancer Center, Tampa, FL</aff><aff id="A6"><label>**</label>Massachusetts General Hospital, Boston, MA</aff><aff id="A7"><label>††</label>Roswell Park Cancer Institute, Buffalo, NY</aff><aff id="A8"><label>‡</label>Duke University, Durham, NC</aff><aff id="A9"><label>‡‡</label>University of Utah, Salt Lake City, UT</aff><aff id="A10"><label>¶¶</label>University of Miami Miller School of Medicine, Miami, FL.</aff><author-notes><corresp id="CR1">Reprint requests to: Dian Wang, MD., Ph.D., Department of Radiation Oncology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53045; Tel: (414) 805-4496; Fax: (414) 805-4369; <email>dwang@mcw.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>9</day><month>8</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>15</day><month>6</month><year>2011</year></pub-date><pub-date pub-type="ppub"><day>15</day><month>11</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>15</day><month>11</month><year>2012</year></pub-date><volume>81</volume><issue>4</issue><fpage>e525</fpage><lpage>e528</lpage><permissions><copyright-statement>© 2011 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2011</copyright-year></permissions><abstract><sec id="S1"><title>Objective</title><p id="P1">To develop an Radiation Therapy Oncology Group (RTOG) atlas delineating gross tumor volume (GTV), and clinical target volume (CTV) to be used for preoperative radiotherapy of primary extremity soft tissue sarcoma (STS).</p></sec><sec sec-type="methods" id="S2"><title>Methods</title><p id="P2">A consensus meeting was held during the RTOG meeting in January 2010 to reach agreement about GTV and CTV delineation on CT images for preoperative radiotherapy of high-grade large extremity STS. Data were presented to address the local extension of STS. Extensive discussion ensued to develop optimal criteria for GTV and CTV delineation on CT images.</p></sec><sec id="S3"><title>Results</title><p id="P3">A consensus was reached on appropriate CT-based GTV and CTV. GTV is gross tumor defined by T1 contrast-enhanced MRI images. Fusion of MRI and CT is recommended to delineate the GTV. CTV for high-grade large STS typically includes GTV plus 3 cm margins in the longitudinal directions. If this causes the field to extend beyond the compartment, the field can be shortened to include the end of a compartment. The radial margin from the lesion should be 1.5 cm including any portion of the tumor not confined by an intact fascial barrier, bone or skin surface.</p></sec><sec id="S4"><title>Conclusion</title><p id="P4">The consensus on GTV and CTV for preoperative radiotherapy of high-grade large extremity STS is available as web-based images as well as descriptive format through the RTOG. This is expected to improve target volume consistency and allow for rigorous evaluation of the benefits and risks of such treatment.</p></sec></abstract><kwd-group><kwd>Sarcoma</kwd><kwd>target definition</kwd><kwd>radiotherapy</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-34 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-33 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-32S4 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-32S3 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-32S2 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-32S1 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-32 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-31S1 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-31 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-30 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-29 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-28S1 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-28 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-27S2 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-27S1 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-27 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-26 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-25 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-24S1 || CA</award-id></award-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U10 CA021661-24 || CA</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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|texte= RTOG Sarcoma Radiation Oncologists Reach Consensus on Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) on Computed Tomographic Images for Preoperative Radiotherapy of Primary Soft Tissue Sarcoma of Extremity in RTOG Studies
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