New Horizons for Imaging Lymphatic Function
Identifieur interne : 002A02 ( Pmc/Curation ); précédent : 002A01; suivant : 002A03New Horizons for Imaging Lymphatic Function
Auteurs : Ruchi Sharma [États-Unis] ; Juliet A. Wendt [États-Unis] ; John C. Rasmussen [États-Unis] ; Kristen E. Adams [États-Unis] ; Milton V. Marshall [États-Unis] ; Eva M. Sevick-Muraca [États-Unis]Source :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 2008.
Abstract
In this review, we provide a comprehensive summary of noninvasive imaging modalities used clinically for the diagnosis of lymphatic diseases, new imaging agents for assessing lymphatic architecture and cancer status of lymph nodes, and emerging near-infrared (NIR) fluorescent optical imaging technologies and agents for functional lymphatic imaging. Given the promise of NIR optical imaging, we provide example results of functional lymphatic imaging in mice, swine, and humans, showing the ability of this technology to quantify lymph velocity and frequencies of propulsion resulting from the contractility of lymphatic structures.
Url:
DOI: 10.1196/annals.1413.002
PubMed: 18519956
PubMed Central: 3094766
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Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, USA</aff>
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<author-notes><corresp id="FN1">Address for correspondence: Eva M. Sevick-Muraca, Division of Molecular Imaging, Baylor College of Medicine, One Baylor Plaza, BCM 360, Houston, TX 77030. Voice: +1-713-798-3684; fax: +1-713-798-2749. <email>evas@bcm.edu</email>
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<kwd-group><kwd>lymph flow</kwd>
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