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Socioeconomic Factors Associated with Adjuvant Hormonal Therapy Use in Older Breast Cancer Survivors

Identifieur interne : 002777 ( Pmc/Curation ); précédent : 002776; suivant : 002778

Socioeconomic Factors Associated with Adjuvant Hormonal Therapy Use in Older Breast Cancer Survivors

Auteurs : Tina W. F. Yen ; Linda K. Czypinski ; Rodney Sparapani ; Changbin Guo ; Purushottam W. Laud ; Liliana E. Pezzin ; Ann B. Nattinger

Source :

RBID : PMC:3010527

Abstract

BACKGROUND

We sought to identify socioeconomic (SES) factors associated with adjuvant hormonal therapy (HT) use among a contemporary population of older breast cancer survivors.

METHODS

Telephone surveys were conducted among women (65–89 years) residing in 4 states (CA, FL, IL, NY) who underwent initial breast cancer surgery in 2003. Demographic, SES, and treatment information was collected.

RESULTS

Of the 2,191 women, 67% received adjuvant HT with either tamoxifen or an aromatase inhibitor (AI); 71% of these women were on an AI. When adjusting for multiple demographic and SES factors, predictors of HT use were: better education (high school degree or higher), better informational/emotional support, and younger age (65 – 79 years). Race/ethnicity, income, and insurance coverage for medication costs were not associated with receiving HT. For those on HT, when adjusting for all other factors, women were more likely to be treated with an AI if they had insurance coverage for some or all medication costs, were wealthier, had better informational/emotional support, and were younger (65 – 69 years).

CONCLUSIONS

The majority of older women in this population-based cohort received adjuvant HT and the adoption of AIs was early. Providers should be aware that a woman’s education level and support system influence her decision to take HT. Given the high cost of AIs, its benefits in postmenopausal women with hormone receptor-positive breast cancer, and our finding that women with no insurance coverage for medication costs were significantly less likely to receive an AI, we recommend that policy-makers address this issue.


Url:
DOI: 10.1002/cncr.25412
PubMed: 20824718
PubMed Central: 3010527

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PMC:3010527

Le document en format XML

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<name sortKey="Yen, Tina W F" sort="Yen, Tina W F" uniqKey="Yen T" first="Tina W. F." last="Yen">Tina W. F. Yen</name>
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<name sortKey="Czypinski, Linda K" sort="Czypinski, Linda K" uniqKey="Czypinski L" first="Linda K." last="Czypinski">Linda K. Czypinski</name>
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<name sortKey="Sparapani, Rodney" sort="Sparapani, Rodney" uniqKey="Sparapani R" first="Rodney" last="Sparapani">Rodney Sparapani</name>
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<name sortKey="Guo, Changbin" sort="Guo, Changbin" uniqKey="Guo C" first="Changbin" last="Guo">Changbin Guo</name>
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<name sortKey="Laud, Purushottam W" sort="Laud, Purushottam W" uniqKey="Laud P" first="Purushottam W." last="Laud">Purushottam W. Laud</name>
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<name sortKey="Pezzin, Liliana E" sort="Pezzin, Liliana E" uniqKey="Pezzin L" first="Liliana E." last="Pezzin">Liliana E. Pezzin</name>
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<title level="j">Cancer</title>
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<div type="abstract" xml:lang="en">
<sec id="S1">
<title>BACKGROUND</title>
<p id="P1">We sought to identify socioeconomic (SES) factors associated with adjuvant hormonal therapy (HT) use among a contemporary population of older breast cancer survivors.</p>
</sec>
<sec sec-type="methods" id="S2">
<title>METHODS</title>
<p id="P2">Telephone surveys were conducted among women (65–89 years) residing in 4 states (CA, FL, IL, NY) who underwent initial breast cancer surgery in 2003. Demographic, SES, and treatment information was collected.</p>
</sec>
<sec id="S3">
<title>RESULTS</title>
<p id="P3">Of the 2,191 women, 67% received adjuvant HT with either tamoxifen or an aromatase inhibitor (AI); 71% of these women were on an AI. When adjusting for multiple demographic and SES factors, predictors of HT use were: better education (high school degree or higher), better informational/emotional support, and younger age (65 – 79 years). Race/ethnicity, income, and insurance coverage for medication costs were not associated with receiving HT. For those on HT, when adjusting for all other factors, women were more likely to be treated with an AI if they had insurance coverage for some or all medication costs, were wealthier, had better informational/emotional support, and were younger (65 – 69 years).</p>
</sec>
<sec id="S4">
<title>CONCLUSIONS</title>
<p id="P4">The majority of older women in this population-based cohort received adjuvant HT and the adoption of AIs was early. Providers should be aware that a woman’s education level and support system influence her decision to take HT. Given the high cost of AIs, its benefits in postmenopausal women with hormone receptor-positive breast cancer, and our finding that women with no insurance coverage for medication costs were significantly less likely to receive an AI, we recommend that policy-makers address this issue.</p>
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<journal-id journal-id-type="nlm-journal-id">0374236</journal-id>
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<article-title>Socioeconomic Factors Associated with Adjuvant Hormonal Therapy Use in Older Breast Cancer Survivors</article-title>
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<contrib contrib-type="author">
<name>
<surname>Yen</surname>
<given-names>Tina W.F.</given-names>
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<surname>Czypinski</surname>
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<given-names>Rodney</given-names>
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<given-names>Liliana E.</given-names>
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<contrib contrib-type="author">
<name>
<surname>Nattinger</surname>
<given-names>Ann B.</given-names>
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<aff id="A1">Division of General Surgery (TWY), Division of Biostatistics (RS, CG, PWL), and Department of Medicine (LKC, LEP, ABN), and Center for Patient Care and Outcomes Research, Medical College of Wisconsin, Milwaukee, WI</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">Correspondence: Tina W.F. Yen, MD, MS, Division of General Surgery, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226, Telephone: 414-805-5495, FAX: 414-805-5934,
<email>tyen@mcw.edu</email>
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<pub-date pub-type="nihms-submitted">
<day>28</day>
<month>5</month>
<year>2010</year>
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<pub-date pub-type="epub">
<day>7</day>
<month>9</month>
<year>2010</year>
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<pub-date pub-type="ppub">
<day>15</day>
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<year>2011</year>
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<pub-date pub-type="pmc-release">
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<month>1</month>
<year>2012</year>
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<volume>117</volume>
<issue>2</issue>
<fpage>398</fpage>
<lpage>405</lpage>
<abstract>
<sec id="S1">
<title>BACKGROUND</title>
<p id="P1">We sought to identify socioeconomic (SES) factors associated with adjuvant hormonal therapy (HT) use among a contemporary population of older breast cancer survivors.</p>
</sec>
<sec sec-type="methods" id="S2">
<title>METHODS</title>
<p id="P2">Telephone surveys were conducted among women (65–89 years) residing in 4 states (CA, FL, IL, NY) who underwent initial breast cancer surgery in 2003. Demographic, SES, and treatment information was collected.</p>
</sec>
<sec id="S3">
<title>RESULTS</title>
<p id="P3">Of the 2,191 women, 67% received adjuvant HT with either tamoxifen or an aromatase inhibitor (AI); 71% of these women were on an AI. When adjusting for multiple demographic and SES factors, predictors of HT use were: better education (high school degree or higher), better informational/emotional support, and younger age (65 – 79 years). Race/ethnicity, income, and insurance coverage for medication costs were not associated with receiving HT. For those on HT, when adjusting for all other factors, women were more likely to be treated with an AI if they had insurance coverage for some or all medication costs, were wealthier, had better informational/emotional support, and were younger (65 – 69 years).</p>
</sec>
<sec id="S4">
<title>CONCLUSIONS</title>
<p id="P4">The majority of older women in this population-based cohort received adjuvant HT and the adoption of AIs was early. Providers should be aware that a woman’s education level and support system influence her decision to take HT. Given the high cost of AIs, its benefits in postmenopausal women with hormone receptor-positive breast cancer, and our finding that women with no insurance coverage for medication costs were significantly less likely to receive an AI, we recommend that policy-makers address this issue.</p>
</sec>
</abstract>
<kwd-group>
<kwd>breast cancer</kwd>
<kwd>hormonal therapy</kwd>
<kwd>tamoxifen</kwd>
<kwd>aromatase inhibitors</kwd>
<kwd>surgery</kwd>
</kwd-group>
<contract-num rid="CA1">R01 CA081379-08 ||CA</contract-num>
<contract-num rid="CA1">K07 CA125586-04 ||CA</contract-num>
<contract-sponsor id="CA1">National Cancer Institute : NCI</contract-sponsor>
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