Subungual Nail Pigmentation and Malalignment of the Great Toe Nail in a Cancer Patient - A Diagnostic Challenge
Identifieur interne : 002359 ( Pmc/Curation ); précédent : 002358; suivant : 002360Subungual Nail Pigmentation and Malalignment of the Great Toe Nail in a Cancer Patient - A Diagnostic Challenge
Auteurs : Uwe Wollina ; Georgi TchernevSource :
- Open Access Macedonian Journal of Medical Sciences [ 1857-9655 ] ; 2017.
Abstract
Subungual pigmentation may have a variety of underlying pathologies, but clinicians should consider malignancies such as subungual melanoma or metastasis, even if they are not common. A delayed diagnosis can dramatically worsen the prognosis. Therefore, histologic examination is highly recommended. We present a 75-year-old female cancer patient presenting with subungual blackish pigmentation of the great toe nail for several years suspicious of a subungual melanoma even by dermoscopy. Nail avulsion and histological investigations excluded melanoma. The final diagnosis was subungual hematoma with growth malalignment of the great toe nail.
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DOI: 10.3889/oamjms.2017.084
PubMed: 28785334
PubMed Central: 5535659
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A delayed diagnosis can dramatically worsen the prognosis. Therefore, histologic examination is highly recommended. We present a 75-year-old female cancer patient presenting with subungual blackish pigmentation of the great toe nail for several years suspicious of a subungual melanoma even by dermoscopy. Nail avulsion and histological investigations excluded melanoma. The final diagnosis was subungual hematoma with growth malalignment of the great toe nail.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wollina, U" uniqKey="Wollina U">U Wollina</name></author><author><name sortKey="Nenoff, P" uniqKey="Nenoff P">P Nenoff</name></author><author><name sortKey="Haroske, G" uniqKey="Haroske G">G Haroske</name></author><author><name sortKey="Haenssle, Ha" uniqKey="Haenssle H">HA Haenssle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cohen, Pr" uniqKey="Cohen P">PR Cohen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tronnier, M" uniqKey="Tronnier M">M Tronnier</name></author><author><name sortKey="Semkova, K" uniqKey="Semkova K">K Semkova</name></author><author><name sortKey="Wollina, U" uniqKey="Wollina U">U Wollina</name></author><author><name sortKey="Tchernev, G" uniqKey="Tchernev G">G Tchernev</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Sy" uniqKey="Kim S">SY Kim</name></author><author><name sortKey="Yun, Sj" uniqKey="Yun S">SJ Yun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baran, R" uniqKey="Baran R">R Baran</name></author><author><name sortKey="Kechijian, P" uniqKey="Kechijian P">P Kechijian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tchernev, G" uniqKey="Tchernev G">G Tchernev</name></author><author><name sortKey="Chokoeva, Aa" uniqKey="Chokoeva A">AA Chokoeva</name></author><author><name sortKey="Wollina, U" uniqKey="Wollina U">U Wollina</name></author><author><name sortKey="Lotti, T" uniqKey="Lotti T">T Lotti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mun, Jh" uniqKey="Mun J">JH Mun</name></author><author><name sortKey="Kim, Gw" uniqKey="Kim G">GW Kim</name></author><author><name sortKey="Jwa, Sw" uniqKey="Jwa S">SW Jwa</name></author><author><name sortKey="Song, M" uniqKey="Song M">M Song</name></author><author><name sortKey="Kim, Hs" uniqKey="Kim H">HS Kim</name></author><author><name sortKey="Ko, Hc" uniqKey="Ko H">HC Ko</name></author><author><name sortKey="Kim, Bs" uniqKey="Kim B">BS Kim</name></author><author><name sortKey="Kim, Mb" uniqKey="Kim M">MB Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deinlein, T" uniqKey="Deinlein T">T Deinlein</name></author><author><name sortKey="Hofmann Wellenhof, R" uniqKey="Hofmann Wellenhof R">R Hofmann-Wellenhof</name></author><author><name sortKey="Zalaudek, I" uniqKey="Zalaudek I">I Zalaudek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chaniotakis, I" uniqKey="Chaniotakis I">I Chaniotakis</name></author><author><name sortKey="Bonitsis, N" uniqKey="Bonitsis N">N Bonitsis</name></author><author><name sortKey="Stergiopoulou, C" uniqKey="Stergiopoulou C">C Stergiopoulou</name></author><author><name sortKey="Kiorpelidou, D" uniqKey="Kiorpelidou D">D Kiorpelidou</name></author><author><name sortKey="Bassukas, Id" uniqKey="Bassukas I">ID Bassukas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaatz, M" uniqKey="Kaatz M">M Kaatz</name></author><author><name sortKey="Wenzel, H C" uniqKey="Wenzel H">H-C Wenzel</name></author><author><name sortKey="Trebing, D" uniqKey="Trebing D">D Trebing</name></author><author><name sortKey="Barta, U" uniqKey="Barta U">U Barta</name></author><author><name sortKey="Wollina, U" uniqKey="Wollina U">U Wollina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mishra, Ak" uniqKey="Mishra A">AK Mishra</name></author><author><name sortKey="George, Aa" uniqKey="George A">AA George</name></author><author><name sortKey="George, L" uniqKey="George L">L George</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Decker, A" uniqKey="Decker A">A Decker</name></author><author><name sortKey="Scher, Rk" uniqKey="Scher R">RK Scher</name></author><author><name sortKey="Avarbock, A" uniqKey="Avarbock A">A Avarbock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wollina, U" uniqKey="Wollina U">U Wollina</name></author><author><name sortKey="Wollina, K" uniqKey="Wollina K">K Wollina</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Braswell, Ma" uniqKey="Braswell M">MA Braswell</name></author><author><name sortKey="Daniel, Cr" uniqKey="Daniel C">CR Daniel</name></author><author><name sortKey="Brodell, Rt" uniqKey="Brodell R">RT Brodell</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Open Access Maced J Med Sci</journal-id><journal-id journal-id-type="iso-abbrev">Open Access Maced J Med Sci</journal-id><journal-title-group><journal-title>Open Access Macedonian Journal of Medical Sciences</journal-title></journal-title-group><issn pub-type="epub">1857-9655</issn><publisher><publisher-name>ID Design 2012/DOOEL Skopje</publisher-name><publisher-loc>Republic of Macedonia</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28785334</article-id><article-id pub-id-type="pmc">5535659</article-id><article-id pub-id-type="publisher-id">OAMJMS-5-467</article-id><article-id pub-id-type="doi">10.3889/oamjms.2017.084</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Subungual Nail Pigmentation and Malalignment of the Great Toe Nail in a Cancer Patient - A Diagnostic Challenge</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Wollina</surname><given-names>Uwe</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Tchernev</surname><given-names>Georgi</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib></contrib-group><aff id="aff1"><label>1</label><italic>Biological Department of Dermatology and Allergology, Municipal Hospital Dresden, Academic Teaching Hospital of the Technical University of Dresden, Friedrichstrasse 41, 01067 Dresden, Germany</italic></aff><aff id="aff2"><label>2</label><italic>Department of Dermatology, Venereology and Dermatologic Surgery, Medical Institute of Ministry of Interior, and Onkoderma Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria</italic></aff><author-notes><corresp id="cor1"><label>*</label><bold>Correspondence:</bold> Uwe Wollina. Biological Department of Dermatology and Allergology, Municipal Hospital Dresden, Academic Teaching Hospital of the Technical University of Dresden, Friedrichstrasse 41, 01067 Dresden, Germany. E-mail: <email xlink:href="wollina-uw@khdf.de">wollina-uw@khdf.de</email></corresp></author-notes><pub-date pub-type="collection"><day>25</day><month>7</month><year>2017</year></pub-date><pub-date pub-type="epub"><day>20</day><month>7</month><year>2017</year></pub-date><volume>5</volume><issue>4</issue><fpage>467</fpage><lpage>469</lpage><history><date date-type="received"><day>30</day><month>3</month><year>2017</year></date><date date-type="rev-recd"><day>21</day><month>4</month><year>2017</year></date><date date-type="accepted"><day>23</day><month>4</month><year>2017</year></date></history><permissions><copyright-statement>Copyright: © 2017 Uwe Wollina, Georgi Tchernev.</copyright-statement><copyright-year>2017</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/CC BY-NC/4.0"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).</license-p></license></permissions><abstract><p>Subungual pigmentation may have a variety of underlying pathologies, but clinicians should consider malignancies such as subungual melanoma or metastasis, even if they are not common. A delayed diagnosis can dramatically worsen the prognosis. Therefore, histologic examination is highly recommended. We present a 75-year-old female cancer patient presenting with subungual blackish pigmentation of the great toe nail for several years suspicious of a subungual melanoma even by dermoscopy. Nail avulsion and histological investigations excluded melanoma. The final diagnosis was subungual hematoma with growth malalignment of the great toe nail.</p></abstract><kwd-group><kwd>Nail apparatus</kwd><kwd>subungual pigmentation</kwd><kwd>cancer</kwd><kwd>melanoma</kwd><kwd>hematoma</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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