An unusual cutaneous of B-cell chronic lymphocytic leukemia presenting as a massive left-sided body ecchymosis
Identifieur interne : 002324 ( Pmc/Curation ); précédent : 002323; suivant : 002325An unusual cutaneous of B-cell chronic lymphocytic leukemia presenting as a massive left-sided body ecchymosis
Auteurs : Lilia Bekel [France] ; Florie Dhaille [France] ; Guillaume Chaby [France] ; Henri Sevestre [France] ; Bruno Royer [France] ; Caroline Defossez-Tribout [France] ; Florian Lombart [France] ; Ali Dadban [France] ; Catherine Lok [France]Source :
- JAAD Case Reports [ 2352-5126 ] ; 2015.
Url:
DOI: 10.1016/j.jdcr.2014.12.001
PubMed: 27051680
PubMed Central: 4802566
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An unusual cutaneous of B-cell chronic lymphocytic leukemia presenting as a massive left-sided body ecchymosis</title><author><name sortKey="Bekel, Lilia" sort="Bekel, Lilia" uniqKey="Bekel L" first="Lilia" last="Bekel">Lilia Bekel</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Dhaille, Florie" sort="Dhaille, Florie" uniqKey="Dhaille F" first="Florie" last="Dhaille">Florie Dhaille</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Chaby, Guillaume" sort="Chaby, Guillaume" uniqKey="Chaby G" first="Guillaume" last="Chaby">Guillaume Chaby</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Sevestre, Henri" sort="Sevestre, Henri" uniqKey="Sevestre H" first="Henri" last="Sevestre">Henri Sevestre</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Pathology, Hôpital Sud, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Pathology, Hôpital Sud, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Royer, Bruno" sort="Royer, Bruno" uniqKey="Royer B" first="Bruno" last="Royer">Bruno Royer</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Clinical Haematology, Hôpital Sud, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Haematology, Hôpital Sud, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Defossez Tribout, Caroline" sort="Defossez Tribout, Caroline" uniqKey="Defossez Tribout C" first="Caroline" last="Defossez-Tribout">Caroline Defossez-Tribout</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Lombart, Florian" sort="Lombart, Florian" uniqKey="Lombart F" first="Florian" last="Lombart">Florian Lombart</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Dadban, Ali" sort="Dadban, Ali" uniqKey="Dadban A" first="Ali" last="Dadban">Ali Dadban</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Lok, Catherine" sort="Lok, Catherine" uniqKey="Lok C" first="Catherine" last="Lok">Catherine Lok</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27051680</idno><idno type="pmc">4802566</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802566</idno><idno type="RBID">PMC:4802566</idno><idno type="doi">10.1016/j.jdcr.2014.12.001</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">002325</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002325</idno><idno type="wicri:Area/Pmc/Curation">002324</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002324</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">An unusual cutaneous of B-cell chronic lymphocytic leukemia presenting as a massive left-sided body ecchymosis</title><author><name sortKey="Bekel, Lilia" sort="Bekel, Lilia" uniqKey="Bekel L" first="Lilia" last="Bekel">Lilia Bekel</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Dhaille, Florie" sort="Dhaille, Florie" uniqKey="Dhaille F" first="Florie" last="Dhaille">Florie Dhaille</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Chaby, Guillaume" sort="Chaby, Guillaume" uniqKey="Chaby G" first="Guillaume" last="Chaby">Guillaume Chaby</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Sevestre, Henri" sort="Sevestre, Henri" uniqKey="Sevestre H" first="Henri" last="Sevestre">Henri Sevestre</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Pathology, Hôpital Sud, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Pathology, Hôpital Sud, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Royer, Bruno" sort="Royer, Bruno" uniqKey="Royer B" first="Bruno" last="Royer">Bruno Royer</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Clinical Haematology, Hôpital Sud, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Haematology, Hôpital Sud, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Defossez Tribout, Caroline" sort="Defossez Tribout, Caroline" uniqKey="Defossez Tribout C" first="Caroline" last="Defossez-Tribout">Caroline Defossez-Tribout</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Lombart, Florian" sort="Lombart, Florian" uniqKey="Lombart F" first="Florian" last="Lombart">Florian Lombart</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Dadban, Ali" sort="Dadban, Ali" uniqKey="Dadban A" first="Ali" last="Dadban">Ali Dadban</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author><author><name sortKey="Lok, Catherine" sort="Lok, Catherine" uniqKey="Lok C" first="Catherine" last="Lok">Catherine Lok</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens</wicri:regionArea></affiliation></author></analytic><series><title level="j">JAAD Case Reports</title><idno type="eISSN">2352-5126</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cho Vega, J H" uniqKey="Cho Vega J">J.H. Cho-Vega</name></author><author><name sortKey="Medeiros, L J" uniqKey="Medeiros L">L.J. Medeiros</name></author><author><name sortKey="Prieto, V G" uniqKey="Prieto V">V.G. Prieto</name></author><author><name sortKey="Vega, F" uniqKey="Vega F">F. Vega</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cerroni, L" uniqKey="Cerroni L">L. Cerroni</name></author><author><name sortKey="Zenahlik, P" uniqKey="Zenahlik P">P. Zenahlik</name></author><author><name sortKey="Hofler, G" uniqKey="Hofler G">G. Höfler</name></author><author><name sortKey="Kaddu, S" uniqKey="Kaddu S">S. Kaddu</name></author><author><name sortKey="Smolle, J" uniqKey="Smolle J">J. Smolle</name></author><author><name sortKey="Kerl, H" uniqKey="Kerl H">H. Kerl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Su, W P" uniqKey="Su W">W.P. Su</name></author><author><name sortKey="Buechner, S A" uniqKey="Buechner S">S.A. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">JAAD Case Rep</journal-id><journal-id journal-id-type="iso-abbrev">JAAD Case Rep</journal-id><journal-title-group><journal-title>JAAD Case Reports</journal-title></journal-title-group><issn pub-type="epub">2352-5126</issn><publisher><publisher-name>Elsevier</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27051680</article-id><article-id pub-id-type="pmc">4802566</article-id><article-id pub-id-type="publisher-id">S2352-5126(14)00021-6</article-id><article-id pub-id-type="doi">10.1016/j.jdcr.2014.12.001</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>An unusual cutaneous of B-cell chronic lymphocytic leukemia presenting as a massive left-sided body ecchymosis</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bekel</surname><given-names>Lilia</given-names></name><degrees>MD</degrees><email>lilia.bekel@gmail.com</email><xref rid="aff1" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">∗</xref></contrib><contrib contrib-type="author"><name><surname>Dhaille</surname><given-names>Florie</given-names></name><degrees>MD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Chaby</surname><given-names>Guillaume</given-names></name><degrees>MD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Sevestre</surname><given-names>Henri</given-names></name><degrees>MD, PhD</degrees><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author"><name><surname>Royer</surname><given-names>Bruno</given-names></name><degrees>MD</degrees><xref rid="aff3" ref-type="aff">c</xref></contrib><contrib contrib-type="author"><name><surname>Defossez-Tribout</surname><given-names>Caroline</given-names></name><degrees>MD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Lombart</surname><given-names>Florian</given-names></name><degrees>MD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Dadban</surname><given-names>Ali</given-names></name><degrees>MD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Lok</surname><given-names>Catherine</given-names></name><degrees>MD, PhD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Department of Dermatology, Hôpital Nord, University of Amiens, Amiens, France</aff><aff id="aff2"><label>b</label>Department of Pathology, Hôpital Sud, University of Amiens, Amiens, France</aff><aff id="aff3"><label>c</label>Department of Clinical Haematology, Hôpital Sud, University of Amiens, Amiens, France</aff><author-notes><corresp id="cor1"><label>∗</label>Correspondence to: Dr Lilia Bekel, MD, Service de Dermatologie, Hôpital Nord, Place Victor Pauchet, 80054 Amiens Cedex, France 61. <email>lilia.bekel@gmail.com</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>05</day><month>2</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="collection"><month>3</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>05</day><month>2</month><year>2015</year></pub-date><volume>1</volume><issue>2</issue><fpage>49</fpage><lpage>50</lpage><permissions><copyright-statement>© 2014 by the American Academy of Dermatology, Inc. Published by Elsevier, Inc.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>American Academy of Dermatology, Inc.</copyright-holder><license license-type="CC BY-NC-ND" xlink:href="http://creativecommons.org/licenses/by-nc-nd/3.0/"><license-p>This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).</license-p></license></permissions><kwd-group><title>Key words</title><kwd>B-chronic lymphocytic leukemia</kwd><kwd>ecchymosis</kwd><kwd>lateralization</kwd><kwd>leukemia cutis</kwd><kwd>purpura</kwd><kwd>skin mosaicism</kwd></kwd-group><kwd-group><title>Abbreviations used</title><kwd>B-CLL, B-cell chronic lymphocytic leukemia</kwd><kwd>LC, leukemia cutis</kwd></kwd-group></article-meta></front><floats-group><fig id="fig1"><label>Fig 1</label><caption><p><bold>A</bold> and <bold>B</bold>, Extensive left-sided ecchymosis on the left thorax (<bold>A</bold>), and left upper (<bold>A</bold>) and lower extremities (<bold>B</bold>). <bold>C</bold>, Histologic sections show perivascular infiltration of leukemia cells in the dermis. Dilated superficial dermal vessels were noted. <bold>D-F</bold>, Immunohistochemical studies found that the leukemic cells were positive for CD20 (<bold>D</bold>), CD23 (<bold>E</bold>), and CD5 (<bold>F</bold>). <bold>G</bold>, Complete resolution of the left-sided ecchymosis 8 months after a combination treatment of bendamustine and rituximab. (<bold>A</bold> and <bold>B</bold>, Hematoxylin-eosin stain; original magnifications: ×100; <bold>C</bold> and <bold>D</bold>, immunohistochemical stains; original magnifications: ×200.)</p></caption><graphic xlink:href="gr1"></graphic></fig></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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