Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series
Identifieur interne : 002261 ( Pmc/Curation ); précédent : 002260; suivant : 002262Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series
Auteurs : Pelin Ozcan Kara [Turquie] ; Emel Ceylan Gunay [Turquie] ; Alihan Erdogan [Turquie]Source :
- International Journal of Endocrinology and Metabolism [ 1726-913X ] ; 2014.
Abstract
Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly.
Non-physiological Iodine-131 (I-131) extra-thyroidal uptake detected on post-therapy or diagnostic I-131 scanning are not always interpreted as functioning metastatic thyroid cancer.
This study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal I-131 accumulation in whole-body I-131 imaging.
Url:
DOI: 10.5812/ijem.9329
PubMed: 24696698
PubMed Central: 3968977
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<front><div type="abstract" xml:lang="en"><sec><title>Introduction:</title>
<p>Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly.</p>
</sec>
<sec><title>Case Presentation:</title>
<p>Non-physiological Iodine-131 (I-131) extra-thyroidal uptake detected on post-therapy or diagnostic I-131 scanning are not always interpreted as functioning metastatic thyroid cancer.</p>
</sec>
<sec><title>Conclusions:</title>
<p>This study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal I-131 accumulation in whole-body I-131 imaging.</p>
</sec>
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Int J Endocrinol Metab</journal-id>
<journal-id journal-id-type="iso-abbrev">Int J Endocrinol Metab</journal-id>
<journal-id journal-id-type="doi">10.5812/ijem</journal-id>
<journal-id journal-id-type="publisher-id">Kowsar</journal-id>
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<article-id pub-id-type="pmc">3968977</article-id>
<article-id pub-id-type="doi">10.5812/ijem.9329</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group><article-title>Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Ozcan Kara</surname>
<given-names>Pelin</given-names>
</name>
<xref ref-type="aff" rid="aff30423">1</xref>
<xref ref-type="corresp" rid="cor30424">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Gunay</surname>
<given-names>Emel Ceylan</given-names>
</name>
<xref ref-type="aff" rid="aff30423">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Erdogan</surname>
<given-names>Alihan</given-names>
</name>
<xref ref-type="aff" rid="aff30423">1</xref>
</contrib>
</contrib-group>
<aff id="aff30423"><label>1</label>
Department of Nuclear Medicine, Faculty of Medicine, Mersin University , Mersin, Turkey</aff>
<author-notes><corresp id="cor30424"><label>*</label>
Corresponding author: Pelin Ozcan Kara, Department of Nuclear Medicine, Faculty of Medicine, Mersin University, Mersin, Turkey. Tel: +90-3243367008, Fax: +90-3243367008, E-mail: <email>ppelinozcan@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="epub"><day>01</day>
<month>1</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="collection"><month>1</month>
<year>2014</year>
</pub-date>
<volume>12</volume>
<issue>1</issue>
<elocation-id>e9329</elocation-id>
<history><date date-type="received"><day>12</day>
<month>12</month>
<year>2012</year>
</date>
<date date-type="rev-recd"><day>02</day>
<month>3</month>
<year>2013</year>
</date>
<date date-type="accepted"><day>09</day>
<month>7</month>
<year>2013</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2014, Research Institute For Endocrine Sciences and Iran Endocrine Society; Published by Kowsar Corp.</copyright-statement>
<copyright-year>2014</copyright-year>
<license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/3.0/"><license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p>
</license>
</permissions>
<abstract><sec><title>Introduction:</title>
<p>Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly.</p>
</sec>
<sec><title>Case Presentation:</title>
<p>Non-physiological Iodine-131 (I-131) extra-thyroidal uptake detected on post-therapy or diagnostic I-131 scanning are not always interpreted as functioning metastatic thyroid cancer.</p>
</sec>
<sec><title>Conclusions:</title>
<p>This study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal I-131 accumulation in whole-body I-131 imaging.</p>
</sec>
</abstract>
<kwd-group kwd-group-type="author"><kwd>Thyroid Cancer</kwd>
<kwd>Radioiodine Scan</kwd>
<kwd>False Positive</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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