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Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Identifieur interne : 002261 ( Pmc/Curation ); précédent : 002260; suivant : 002262

Radioiodine Contamination Artifacts and Unusual Patterns of Accumulation in Whole-body I-131 Imaging: A Case Series

Auteurs : Pelin Ozcan Kara [Turquie] ; Emel Ceylan Gunay [Turquie] ; Alihan Erdogan [Turquie]

Source :

RBID : PMC:3968977

Abstract

Introduction:

Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly.

Case Presentation:

Non-physiological Iodine-131 (I-131) extra-thyroidal uptake detected on post-therapy or diagnostic I-131 scanning are not always interpreted as functioning metastatic thyroid cancer.

Conclusions:

This study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal I-131 accumulation in whole-body I-131 imaging.


Url:
DOI: 10.5812/ijem.9329
PubMed: 24696698
PubMed Central: 3968977

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PMC:3968977

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Department of Nuclear Medicine, Faculty of Medicine, Mersin University , Mersin, Turkey</aff>
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Corresponding author: Pelin Ozcan Kara, Department of Nuclear Medicine, Faculty of Medicine, Mersin University, Mersin, Turkey. Tel: +90-3243367008, Fax: +90-3243367008, E-mail:
<email>ppelinozcan@gmail.com</email>
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<month>12</month>
<year>2012</year>
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<date date-type="rev-recd">
<day>02</day>
<month>3</month>
<year>2013</year>
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<month>7</month>
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</license>
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<abstract>
<sec>
<title>Introduction:</title>
<p>Radioactive iodine has been used for more than 50 years for the treatment of thyroid diseases. Differentiated thyroid cancers have the ability to trap iodine. Therefore, radioiodine can be used both diagnostically and therapeutically. In the follow-up of patients, it is critical to interpret radioiodine scans correctly.</p>
</sec>
<sec>
<title>Case Presentation:</title>
<p>Non-physiological Iodine-131 (I-131) extra-thyroidal uptake detected on post-therapy or diagnostic I-131 scanning are not always interpreted as functioning metastatic thyroid cancer.</p>
</sec>
<sec>
<title>Conclusions:</title>
<p>This study provides detailed information and case samples of radiodine contamination artifacts and non-physiological, non-metastatic extra-thyroidal I-131 accumulation in whole-body I-131 imaging.</p>
</sec>
</abstract>
<kwd-group kwd-group-type="author">
<kwd>Thyroid Cancer</kwd>
<kwd>Radioiodine Scan</kwd>
<kwd>False Positive</kwd>
</kwd-group>
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</front>
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