Lipedema, a Rare Disease
Identifieur interne : 002112 ( Pmc/Curation ); précédent : 002111; suivant : 002113Lipedema, a Rare Disease
Auteurs : Bae Wook Shin [Corée du Sud] ; Young-Joo Sim [Corée du Sud] ; Ho Joong Jeong [Corée du Sud] ; Ghi Chan Kim [Corée du Sud]Source :
- Annals of Rehabilitation Medicine [ 2234-0645 ] ; 2011.
Abstract
Lipedema is a chronic disease of lipid metabolism that results in the symmetrical impairment of fatty tissue distribution and storage combined with the hyperplasia of individual fat cells. Lipedema occurs almost exclusively in women and is usually associated with a family history and characteristic features. It can be diagnosed based on clinical history and physical examination. Lipedema is usually symmetrical, but spares the feet, is often painful to palpation, and is negative for Stemmer's sign. Additionally, lipedema patients can present with microangiopathies and lipomas. The well-known therapies for lipedema include complex decongestive therapy, pneumatic compression, and diet modifications. However, whether these treatments help reduce swelling is debatable. We encountered a case of lipedema that was initially misdiagnosed as lymphedema. The patient's clinical features and history were different from those typical of lymphedema, prompting a diagnosis of lipedema and she was treated with a complex decongestive therapy program.
Url:
DOI: 10.5535/arm.2011.35.6.922
PubMed: 22506222
PubMed Central: 3309375
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lipedema, a Rare Disease</title><author><name sortKey="Shin, Bae Wook" sort="Shin, Bae Wook" uniqKey="Shin B" first="Bae Wook" last="Shin">Bae Wook Shin</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702</wicri:regionArea></affiliation></author><author><name sortKey="Sim, Young Joo" sort="Sim, Young Joo" uniqKey="Sim Y" first="Young-Joo" last="Sim">Young-Joo Sim</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du 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Wook" uniqKey="Shin B" first="Bae Wook" last="Shin">Bae Wook Shin</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702</wicri:regionArea></affiliation></author><author><name sortKey="Sim, Young Joo" sort="Sim, Young Joo" uniqKey="Sim Y" first="Young-Joo" last="Sim">Young-Joo Sim</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702</wicri:regionArea></affiliation></author><author><name sortKey="Jeong, Ho Joong" sort="Jeong, Ho Joong" uniqKey="Jeong H" first="Ho Joong" last="Jeong">Ho Joong Jeong</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702</wicri:regionArea></affiliation></author><author><name sortKey="Kim, Ghi Chan" sort="Kim, Ghi Chan" uniqKey="Kim G" first="Ghi Chan" last="Kim">Ghi Chan Kim</name><affiliation wicri:level="1"><nlm:aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702</wicri:regionArea></affiliation></author></analytic><series><title level="j">Annals of Rehabilitation Medicine</title><idno type="ISSN">2234-0645</idno><idno type="eISSN">2234-0653</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Lipedema is a chronic disease of lipid metabolism that results in the symmetrical impairment of fatty tissue distribution and storage combined with the hyperplasia of individual fat cells. Lipedema occurs almost exclusively in women and is usually associated with a family history and characteristic features. It can be diagnosed based on clinical history and physical examination. Lipedema is usually symmetrical, but spares the feet, is often painful to palpation, and is negative for Stemmer's sign. Additionally, lipedema patients can present with microangiopathies and lipomas. The well-known therapies for lipedema include complex decongestive therapy, pneumatic compression, and diet modifications. However, whether these treatments help reduce swelling is debatable. We encountered a case of lipedema that was initially misdiagnosed as lymphedema. The patient's clinical features and history were different from those typical of lymphedema, prompting a diagnosis of lipedema and she was treated with a complex decongestive therapy program.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Weisseleder, H" uniqKey="Weisseleder H">H Weisseleder</name></author><author><name sortKey="Schuchhardt, C" uniqKey="Schuchhardt C">C Schuchhardt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Child, Ah" uniqKey="Child A">AH Child</name></author><author><name sortKey="Gordon, Kd" uniqKey="Gordon K">KD Gordon</name></author><author><name sortKey="Sharpe, P" uniqKey="Sharpe P">P Sharpe</name></author><author><name sortKey="Brice, G" uniqKey="Brice G">G Brice</name></author><author><name sortKey="Ostergaard, P" uniqKey="Ostergaard P">P Ostergaard</name></author><author><name sortKey="Jeffery, S" uniqKey="Jeffery S">S Jeffery</name></author><author><name sortKey="Mortimer, Ps" uniqKey="Mortimer P">PS Mortimer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Juther, Je" uniqKey="Juther J">JE Juther</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Foldi, E" uniqKey="Foldi E">E Földi</name></author><author><name sortKey="Foldi, M" uniqKey="Foldi M">M Földi</name></author><author><name sortKey="Stro Enreuther, R" uniqKey="Stro Enreuther R">R Ströβenreuther</name></author><author><name sortKey="Kubik, S" uniqKey="Kubik S">S Kubik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pascucci, A" uniqKey="Pascucci A">A Pascucci</name></author><author><name sortKey="Lynch, Pj" uniqKey="Lynch P">PJ Lynch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szolnoky, G" uniqKey="Szolnoky G">G Szolnoky</name></author><author><name sortKey="Nagy, N" uniqKey="Nagy N">N Nagy</name></author><author><name sortKey="Kovacs, Rk" uniqKey="Kovacs R">RK Kovacs</name></author><author><name sortKey="Dosa Racz, E" uniqKey="Dosa Racz E">E Dosa-Racz</name></author><author><name sortKey="Szabo, A" uniqKey="Szabo A">A Szabo</name></author><author><name sortKey="Barsony, K" uniqKey="Barsony K">K Barsony</name></author><author><name sortKey="Balogh, M" uniqKey="Balogh M">M Balogh</name></author><author><name sortKey="Kemeny, L" uniqKey="Kemeny L">L Kemeny</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rudkin, Gh" uniqKey="Rudkin G">GH Rudkin</name></author><author><name sortKey="Miller, Ta" uniqKey="Miller T">TA Miller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Szolnoky, G" uniqKey="Szolnoky G">G Szolnoky</name></author><author><name sortKey="Borsos, B" uniqKey="Borsos B">B Borsos</name></author><author><name sortKey="Barsony, K" uniqKey="Barsony K">K Barsony</name></author><author><name sortKey="Balogh, M" uniqKey="Balogh M">M Balogh</name></author><author><name sortKey="Kemeny, L" uniqKey="Kemeny L">L Kemeny</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Macdonald, Jm" uniqKey="Macdonald J">JM Macdonald</name></author><author><name sortKey="Sims, N" uniqKey="Sims N">N Sims</name></author><author><name sortKey="Mayrovitz, Hn" uniqKey="Mayrovitz H">HN Mayrovitz</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Rehabil Med</journal-id><journal-id journal-id-type="iso-abbrev">Ann Rehabil Med</journal-id><journal-id journal-id-type="publisher-id">ARM</journal-id><journal-title-group><journal-title>Annals of Rehabilitation Medicine</journal-title></journal-title-group><issn pub-type="ppub">2234-0645</issn><issn pub-type="epub">2234-0653</issn><publisher><publisher-name>Korean Academy of Rehabilitation Medicine</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22506222</article-id><article-id pub-id-type="pmc">3309375</article-id><article-id pub-id-type="doi">10.5535/arm.2011.35.6.922</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Lipedema, a Rare Disease</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Shin</surname><given-names>Bae Wook</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1"></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Sim</surname><given-names>Young-Joo</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1"></xref></contrib><contrib contrib-type="author"><name><surname>Jeong</surname><given-names>Ho Joong</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1"></xref></contrib><contrib contrib-type="author"><name><surname>Kim</surname><given-names>Ghi Chan</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1"></xref></contrib></contrib-group><aff id="A1">Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, Busan 602-702, Korea.</aff><author-notes><corresp>Corresponding author: Young-Joo Sim. Department of Physical Medicine and Rehabilitation, Kosin University College of Medicine, 34, Amnam-dong, Seo-gu, Busan 602-702, Korea. Tel: +82-51-990-6156, Fax: 82-51-241-2019, <email>oggum@hanmail.net</email></corresp></author-notes><pub-date pub-type="ppub"><month>12</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2011</year></pub-date><volume>35</volume><issue>6</issue><fpage>922</fpage><lpage>927</lpage><history><date date-type="received"><day>28</day><month>8</month><year>2011</year></date><date date-type="accepted"><day>11</day><month>11</month><year>2011</year></date></history><permissions><copyright-statement>Copyright © 2011 by Korean Academy of Rehabilitation Medicine</copyright-statement><copyright-year>2011</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc/3.0"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/3.0">http://creativecommons.org/licenses/by-nc/3.0</ext-link>) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Lipedema is a chronic disease of lipid metabolism that results in the symmetrical impairment of fatty tissue distribution and storage combined with the hyperplasia of individual fat cells. Lipedema occurs almost exclusively in women and is usually associated with a family history and characteristic features. It can be diagnosed based on clinical history and physical examination. Lipedema is usually symmetrical, but spares the feet, is often painful to palpation, and is negative for Stemmer's sign. Additionally, lipedema patients can present with microangiopathies and lipomas. The well-known therapies for lipedema include complex decongestive therapy, pneumatic compression, and diet modifications. However, whether these treatments help reduce swelling is debatable. We encountered a case of lipedema that was initially misdiagnosed as lymphedema. The patient's clinical features and history were different from those typical of lymphedema, prompting a diagnosis of lipedema and she was treated with a complex decongestive therapy program.</p></abstract><kwd-group><kwd>Lipedema</kwd><kwd>Lymphedema</kwd><kwd>Complex decongestive therapy</kwd></kwd-group></article-meta></front><floats-group><fig id="F1" position="float"><label>Fig. 1</label><caption><p>Photograph of both lower limbs of the patient. Swelling is seen in both lower limbs except for the feet.</p></caption><graphic xlink:href="arm-35-922-g001"></graphic></fig><fig id="F2" position="float"><label>Fig. 2</label><caption><p>Photograph of the patient's right lateral thigh. Multiple micropetechiae are seen on the right lateral thigh and calf.</p></caption><graphic xlink:href="arm-35-922-g002"></graphic></fig><fig id="F3" position="float"><label>Fig. 3</label><caption><p>Results of Technetium-99m human serum albumin lymphoscintigraphy. (A) Lower extremity Technetium-99m human serum albumin lymphoscintigraphy obtained 30 minutes after the injection of radionuclides revealing normal lymphatic drainage. (B) Lower extremity Technetium-99m human serum albumin lymphoscintigraphy obtained three hours after the injection of radionuclides revealing normal lymphatic drainage.</p></caption><graphic xlink:href="arm-35-922-g003"></graphic></fig><table-wrap id="T1" position="float"><label>Table 1</label><caption><p>Circumference of Both Lower Limbs</p></caption><graphic xlink:href="arm-35-922-i001"></graphic></table-wrap><table-wrap id="T2" position="float"><label>Table 2</label><caption><p>Nerve Conduction Data of Lower Limbs</p></caption><graphic xlink:href="arm-35-922-i002"></graphic></table-wrap></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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