Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease
Identifieur interne : 001777 ( Pmc/Curation ); précédent : 001776; suivant : 001778Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease
Auteurs : P. J. Guillou ; T. G. Brennan ; G. R. GilesSource :
- Gut [ 0017-5749 ] ; 1973.
Abstract
The response of lymphocytes from peripheral blood and mesenteric lymph nodes to stimulation with phytohaemagglutinin
Url:
PubMed: 4692250
PubMed Central: 1412585
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease</title><author><name sortKey="Guillou, P J" sort="Guillou, P J" uniqKey="Guillou P" first="P. J." last="Guillou">P. J. Guillou</name></author><author><name sortKey="Brennan, T G" sort="Brennan, T G" uniqKey="Brennan T" first="T. G." last="Brennan">T. G. Brennan</name></author><author><name sortKey="Giles, G R" sort="Giles, G R" uniqKey="Giles G" first="G. R." last="Giles">G. R. Giles</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">4692250</idno><idno type="pmc">1412585</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1412585</idno><idno type="RBID">PMC:1412585</idno><date when="1973">1973</date><idno type="wicri:Area/Pmc/Corpus">001778</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001778</idno><idno type="wicri:Area/Pmc/Curation">001777</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001777</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease</title><author><name sortKey="Guillou, P J" sort="Guillou, P J" uniqKey="Guillou P" first="P. J." last="Guillou">P. J. Guillou</name></author><author><name sortKey="Brennan, T G" sort="Brennan, T G" uniqKey="Brennan T" first="T. G." last="Brennan">T. G. Brennan</name></author><author><name sortKey="Giles, G R" sort="Giles, G R" uniqKey="Giles G" first="G. R." last="Giles">G. R. Giles</name></author></analytic><series><title level="j">Gut</title><idno type="ISSN">0017-5749</idno><idno type="eISSN">1458-3288</idno><imprint><date when="1973">1973</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The response of lymphocytes from peripheral blood and mesenteric lymph nodes to stimulation with phytohaemagglutinin <italic>in vitro</italic> has been studied in eight patients suffering from active Crohn's disease. Patients with Crohn's disease exhibited reduced responses when compared with similar studies performed in control subjects. The impaired responses of circulating lymphocytes from these patients were marked on culture in autologous serum and were not improved by culture in homologous AB serum. Lymphocytes from lymph nodes directly draining diseased bowel exhibited lower responses than those from nodes at the root of the mesentery, which in turn were lower than those of circulating lymphocytes.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Gut</journal-id><journal-title>Gut</journal-title><issn pub-type="ppub">0017-5749</issn><issn pub-type="epub">1458-3288</issn></journal-meta><article-meta><article-id pub-id-type="pmid">4692250</article-id><article-id pub-id-type="pmc">1412585</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Guillou</surname><given-names>P. J.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Brennan</surname><given-names>T. G.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Giles</surname><given-names>G. R.</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>01</month><year>1973</year></pub-date><volume>14</volume><issue>1</issue><fpage>20</fpage><lpage>24</lpage><abstract><p>The response of lymphocytes from peripheral blood and mesenteric lymph nodes to stimulation with phytohaemagglutinin <italic>in vitro</italic> has been studied in eight patients suffering from active Crohn's disease. Patients with Crohn's disease exhibited reduced responses when compared with similar studies performed in control subjects. The impaired responses of circulating lymphocytes from these patients were marked on culture in autologous serum and were not improved by culture in homologous AB serum. Lymphocytes from lymph nodes directly draining diseased bowel exhibited lower responses than those from nodes at the root of the mesentery, which in turn were lower than those of circulating lymphocytes.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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