A systematic review of factors that shape implementation of mass drug administration for lymphatic filariasis in sub-Saharan Africa
Identifieur interne : 000C79 ( Pmc/Curation ); précédent : 000C78; suivant : 000C80A systematic review of factors that shape implementation of mass drug administration for lymphatic filariasis in sub-Saharan Africa
Auteurs : Adam Silumbwe [Zambie] ; Joseph Mumba Zulu [Zambie] ; Hikabasa Halwindi [Zambie] ; Choolwe Jacobs [Zambie] ; Jessy Zgambo [Zambie] ; Rosalia Dambe [Zambie] ; Mumbi Chola [Zambie] ; Gershom Chongwe [Zambie] ; Charles Michelo [Zambie]Source :
- BMC Public Health [ 1471-2458 ] ; 2017.
Abstract
Understanding factors surrounding the implementation process of mass drug administration for lymphatic filariasis (MDA for LF) elimination programmes is critical for successful implementation of similar interventions. The sub-Saharan Africa (SSA) region records the second highest prevalence of the disease and subsequently several countries have initiated and implemented MDA for LF. Systematic reviews have largely focused on factors that affect coverage and compliance, with less attention on the implementation of MDA for LF activities. This review therefore seeks to document facilitators and barriers to implementation of MDA for LF in sub-Saharan Africa.
A systematic search of databases PubMed, Science Direct and Google Scholar was conducted. English peer-reviewed publications focusing on implementation of MDA for LF from 2000 to 2016 were considered for analysis. Using thematic analysis, we synthesized the final 18 articles to identify key facilitators and barriers to MDA for LF programme implementation.
The main factors facilitating implementation of MDA for LF programmes were awareness creation through innovative community health education programmes, creation of partnerships and collaborations, integration with existing programmes, creation of morbidity management programmes, motivation of community drug distributors (CDDs) through incentives and training, and management of adverse effects. Barriers to implementation included the lack of geographical demarcations and unregistered migrations into rapidly urbanizing areas, major disease outbreaks like the Ebola virus disease in West Africa, delayed drug deliveries at both country and community levels, inappropriate drug delivery strategies, limited number of drug distributors and the large number of households allocated for drug distribution.
Mass drug administration for lymphatic filariasis elimination programmes should design their implementation strategies differently based on specific contextual factors to improve implementation outcomes. Successfully achieving this requires undertaking formative research on the possible constraining and inhibiting factors, and incorporating the findings in the design and implementation of MDA for LF.
Url:
DOI: 10.1186/s12889-017-4414-5
PubMed: 28532397
PubMed Central: 5441010
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<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Understanding factors surrounding the implementation process of mass drug administration for lymphatic filariasis (MDA for LF) elimination programmes is critical for successful implementation of similar interventions. The sub-Saharan Africa (SSA) region records the second highest prevalence of the disease and subsequently several countries have initiated and implemented MDA for LF. Systematic reviews have largely focused on factors that affect coverage and compliance, with less attention on the implementation of MDA for LF activities. This review therefore seeks to document facilitators and barriers to implementation of MDA for LF in sub-Saharan Africa.</p>
</sec>
<sec><title>Methods</title>
<p>A systematic search of databases PubMed, Science Direct and Google Scholar was conducted. English peer-reviewed publications focusing on implementation of MDA for LF from 2000 to 2016 were considered for analysis. Using thematic analysis, we synthesized the final 18 articles to identify key facilitators and barriers to MDA for LF programme implementation.</p>
</sec>
<sec><title>Results</title>
<p>The main factors facilitating implementation of MDA for LF programmes were awareness creation through innovative community health education programmes, creation of partnerships and collaborations, integration with existing programmes, creation of morbidity management programmes, motivation of community drug distributors (CDDs) through incentives and training, and management of adverse effects. Barriers to implementation included the lack of geographical demarcations and unregistered migrations into rapidly urbanizing areas, major disease outbreaks like the Ebola virus disease in West Africa, delayed drug deliveries at both country and community levels, inappropriate drug delivery strategies, limited number of drug distributors and the large number of households allocated for drug distribution.</p>
</sec>
<sec><title>Conclusion</title>
<p>Mass drug administration for lymphatic filariasis elimination programmes should design their implementation strategies differently based on specific contextual factors to improve implementation outcomes. Successfully achieving this requires undertaking formative research on the possible constraining and inhibiting factors, and incorporating the findings in the design and implementation of MDA for LF.</p>
</sec>
</div>
</front>
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<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">BMC Public Health</journal-id>
<journal-id journal-id-type="iso-abbrev">BMC Public Health</journal-id>
<journal-title-group><journal-title>BMC Public Health</journal-title>
</journal-title-group>
<issn pub-type="epub">1471-2458</issn>
<publisher><publisher-name>BioMed Central</publisher-name>
<publisher-loc>London</publisher-loc>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">28532397</article-id>
<article-id pub-id-type="pmc">5441010</article-id>
<article-id pub-id-type="publisher-id">4414</article-id>
<article-id pub-id-type="doi">10.1186/s12889-017-4414-5</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>A systematic review of factors that shape implementation of mass drug administration for lymphatic filariasis in sub-Saharan Africa</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Silumbwe</surname>
<given-names>Adam</given-names>
</name>
<address><email>adamsilumbwe@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zulu</surname>
<given-names>Joseph Mumba</given-names>
</name>
<address><email>josephmumbazulu@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Halwindi</surname>
<given-names>Hikabasa</given-names>
</name>
<address><email>hikabasa@yahoo.com</email>
</address>
<xref ref-type="aff" rid="Aff3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Jacobs</surname>
<given-names>Choolwe</given-names>
</name>
<address><email>choolwe2003@yahoo.com</email>
</address>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Zgambo</surname>
<given-names>Jessy</given-names>
</name>
<address><email>jessyzyambo88@yahoo.co.uk</email>
</address>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Dambe</surname>
<given-names>Rosalia</given-names>
</name>
<address><email>rosadambe@yahoo.co.uk</email>
</address>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chola</surname>
<given-names>Mumbi</given-names>
</name>
<address><email>mumbi24@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Chongwe</surname>
<given-names>Gershom</given-names>
</name>
<address><email>gchongwe@gmail.com</email>
</address>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Michelo</surname>
<given-names>Charles</given-names>
</name>
<address><email>ccmichelo@yahoo.com</email>
</address>
<xref ref-type="aff" rid="Aff4">4</xref>
</contrib>
<aff id="Aff1"><label>1</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8914 5257</institution-id>
<institution-id institution-id-type="GRID">grid.12984.36</institution-id>
<institution>Department of Health Policy and Management, School of Public Health,</institution>
<institution>University of Zambia,</institution>
</institution-wrap>
PO Box 50110, Lusaka, Zambia</aff>
<aff id="Aff2"><label>2</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8914 5257</institution-id>
<institution-id institution-id-type="GRID">grid.12984.36</institution-id>
<institution>Department of Health Promotion and Education, School of Public Health,</institution>
<institution>University of Zambia,</institution>
</institution-wrap>
PO Box 50110, Lusaka, Zambia</aff>
<aff id="Aff3"><label>3</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8914 5257</institution-id>
<institution-id institution-id-type="GRID">grid.12984.36</institution-id>
<institution>Department of Environmental Health, School of Public Health,</institution>
<institution>University of Zambia,</institution>
</institution-wrap>
PO Box 50110, Lusaka, Zambia</aff>
<aff id="Aff4"><label>4</label>
<institution-wrap><institution-id institution-id-type="ISNI">0000 0000 8914 5257</institution-id>
<institution-id institution-id-type="GRID">grid.12984.36</institution-id>
<institution>Department of Epidemiology and Biostatistics, School of Public Health,</institution>
<institution>University of Zambia,</institution>
</institution-wrap>
PO Box 50110, Lusaka, Zambia</aff>
</contrib-group>
<pub-date pub-type="epub"><day>22</day>
<month>5</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>22</day>
<month>5</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="collection"><year>2017</year>
</pub-date>
<volume>17</volume>
<elocation-id>484</elocation-id>
<history><date date-type="received"><day>15</day>
<month>7</month>
<year>2016</year>
</date>
<date date-type="accepted"><day>11</day>
<month>5</month>
<year>2017</year>
</date>
</history>
<permissions><copyright-statement>© The Author(s). 2017</copyright-statement>
<license license-type="OpenAccess"><license-p><bold>Open Access</bold>
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</ext-link>
), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>
) applies to the data made available in this article, unless otherwise stated.</license-p>
</license>
</permissions>
<abstract id="Abs1"><sec><title>Background</title>
<p>Understanding factors surrounding the implementation process of mass drug administration for lymphatic filariasis (MDA for LF) elimination programmes is critical for successful implementation of similar interventions. The sub-Saharan Africa (SSA) region records the second highest prevalence of the disease and subsequently several countries have initiated and implemented MDA for LF. Systematic reviews have largely focused on factors that affect coverage and compliance, with less attention on the implementation of MDA for LF activities. This review therefore seeks to document facilitators and barriers to implementation of MDA for LF in sub-Saharan Africa.</p>
</sec>
<sec><title>Methods</title>
<p>A systematic search of databases PubMed, Science Direct and Google Scholar was conducted. English peer-reviewed publications focusing on implementation of MDA for LF from 2000 to 2016 were considered for analysis. Using thematic analysis, we synthesized the final 18 articles to identify key facilitators and barriers to MDA for LF programme implementation.</p>
</sec>
<sec><title>Results</title>
<p>The main factors facilitating implementation of MDA for LF programmes were awareness creation through innovative community health education programmes, creation of partnerships and collaborations, integration with existing programmes, creation of morbidity management programmes, motivation of community drug distributors (CDDs) through incentives and training, and management of adverse effects. Barriers to implementation included the lack of geographical demarcations and unregistered migrations into rapidly urbanizing areas, major disease outbreaks like the Ebola virus disease in West Africa, delayed drug deliveries at both country and community levels, inappropriate drug delivery strategies, limited number of drug distributors and the large number of households allocated for drug distribution.</p>
</sec>
<sec><title>Conclusion</title>
<p>Mass drug administration for lymphatic filariasis elimination programmes should design their implementation strategies differently based on specific contextual factors to improve implementation outcomes. Successfully achieving this requires undertaking formative research on the possible constraining and inhibiting factors, and incorporating the findings in the design and implementation of MDA for LF.</p>
</sec>
</abstract>
<kwd-group xml:lang="en"><title>Keywords</title>
<kwd>Lymphatic filariasis</kwd>
<kwd>Mass drug administration</kwd>
<kwd>Implementation</kwd>
<kwd>Barriers and facilitators</kwd>
<kwd>Sub-Saharan Africa</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name>
<meta-value>© The Author(s) 2017</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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