Cutaneous metastasis of transitional cell carcinoma of the urinary bladder eight years after the primary: a case report
Identifieur interne : 000A44 ( Pmc/Curation ); précédent : 000A43; suivant : 000A45Cutaneous metastasis of transitional cell carcinoma of the urinary bladder eight years after the primary: a case report
Auteurs : Andrea Nicole LeesSource :
- Journal of Medical Case Reports [ 1752-1947 ] ; 2015.
Abstract
Cutaneous metastasis of bladder carcinoma is extremely rare with a limited number of published cases. An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis, as it can occur months or rarely as in this case, even years, after the primary cancer.
An 81-year-old Caucasian man presented with a one-year history of increasing left leg swelling and a two-month history of a macular-nodular rash on the anterior thigh, on a background of a high-grade (WHO Grade 2 of 3) papillary and invasive transitional cell carcinoma of the bladder in 2006. Following investigations, he was diagnosed as having probable locoregional recurrence of previously resected urothelial cancer of the bladder with extensive retrograde lymphatic permeation into the left thigh with cutaneous eruptions of malignancy. He completed a planned course of palliative radiation therapy to the left thigh lesions (30Gy divided over 10 fractions) as well as the left pelvic node (a total dose of 18Gy divided over six fractions). The disease ran an aggressive course and our patient died six months after the diagnosis of cutaneous metastases.
Metastatic disease should always be considered in the differential diagnosis in patients with a previous history of bladder cancer who present with cutaneous nodules, even many years after the initial diagnosis at the primary site.
Url:
DOI: 10.1186/s13256-015-0585-9
PubMed: 25943325
PubMed Central: 4427993
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Andrea Nicole Lees<affiliation><nlm:aff id="Aff1">Royal Hobart Hospital, 48 Liverpool Street, Hobart, Tasmania 7000 Australia</nlm:aff><wicri:noCountry code="subfield">Tasmania 7000 Australia</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cutaneous metastasis of transitional cell carcinoma of the urinary bladder eight years after the primary: a case report</title><author><name sortKey="Lees, Andrea Nicole" sort="Lees, Andrea Nicole" uniqKey="Lees A" first="Andrea Nicole" last="Lees">Andrea Nicole Lees</name><affiliation><nlm:aff id="Aff1">Royal Hobart Hospital, 48 Liverpool Street, Hobart, Tasmania 7000 Australia</nlm:aff><wicri:noCountry code="subfield">Tasmania 7000 Australia</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25943325</idno><idno type="pmc">4427993</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427993</idno><idno type="RBID">PMC:4427993</idno><idno type="doi">10.1186/s13256-015-0585-9</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000A45</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A45</idno><idno type="wicri:Area/Pmc/Curation">000A44</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000A44</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cutaneous metastasis of transitional cell carcinoma of the urinary bladder eight years after the primary: a case report</title><author><name sortKey="Lees, Andrea Nicole" sort="Lees, Andrea Nicole" uniqKey="Lees A" first="Andrea Nicole" last="Lees">Andrea Nicole Lees</name><affiliation><nlm:aff id="Aff1">Royal Hobart Hospital, 48 Liverpool Street, Hobart, Tasmania 7000 Australia</nlm:aff><wicri:noCountry code="subfield">Tasmania 7000 Australia</wicri:noCountry></affiliation></author></analytic><series><title level="j">Journal of Medical Case Reports</title><idno type="eISSN">1752-1947</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Cutaneous metastasis of bladder carcinoma is extremely rare with a limited number of published cases. An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis, as it can occur months or rarely as in this case, even years, after the primary cancer.</p></sec><sec><title>Case presentation</title><p>An 81-year-old Caucasian man presented with a one-year history of increasing left leg swelling and a two-month history of a macular-nodular rash on the anterior thigh, on a background of a high-grade (WHO Grade 2 of 3) papillary and invasive transitional cell carcinoma of the bladder in 2006. Following investigations, he was diagnosed as having probable locoregional recurrence of previously resected urothelial cancer of the bladder with extensive retrograde lymphatic permeation into the left thigh with cutaneous eruptions of malignancy. He completed a planned course of palliative radiation therapy to the left thigh lesions (30Gy divided over 10 fractions) as well as the left pelvic node (a total dose of 18Gy divided over six fractions). The disease ran an aggressive course and our patient died six months after the diagnosis of cutaneous metastases.</p></sec><sec><title>Conclusions</title><p>Metastatic disease should always be considered in the differential diagnosis in patients with a previous history of bladder cancer who present with cutaneous nodules, even many years after the initial diagnosis at the primary site.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Jaske, G" uniqKey="Jaske G">G Jaske</name></author><author><name sortKey="Stockle, M" uniqKey="Stockle M">M Stockle</name></author><author><name sortKey="Lehmann, J" uniqKey="Lehmann J">J Lehmann</name></author><author><name sortKey="Otto, T" uniqKey="Otto T">T Otto</name></author><author><name sortKey="Krege, S" uniqKey="Krege S">S Krege</name></author><author><name sortKey="Rubben, H" uniqKey="Rubben H">H 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Lee</name></author><author><name sortKey="Huang, Js" uniqKey="Huang J">JS Huang</name></author><author><name sortKey="Chang, Lc" uniqKey="Chang L">LC Chang</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Beautyman, Ej" uniqKey="Beautyman E">EJ Beautyman</name></author><author><name sortKey="Garcia, Cj" uniqKey="Garcia C">CJ Garcia</name></author><author><name sortKey="Sibulkin, D" uniqKey="Sibulkin D">D Sibulkin</name></author><author><name sortKey="Snyder, Pb" uniqKey="Snyder P">PB Snyder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hinshaw, M" uniqKey="Hinshaw M">M Hinshaw</name></author><author><name sortKey="Stratman, E" uniqKey="Stratman E">E Stratman</name></author><author><name sortKey="Warner, T" uniqKey="Warner T">T Warner</name></author><author><name sortKey="Sharata, H" uniqKey="Sharata H">H Sharata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swick, Bl" uniqKey="Swick B">BL Swick</name></author><author><name sortKey="Gordon, Jrs" uniqKey="Gordon J">JRS Gordon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Akman, Y" uniqKey="Akman Y">Y Akman</name></author><author><name sortKey="Cam, K" uniqKey="Cam K">K Cam</name></author><author><name sortKey="Kavak, A" uniqKey="Kavak A">A Kavak</name></author><author><name sortKey="Alper, M" uniqKey="Alper M">M Alper</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Atmaca, Af" uniqKey="Atmaca A">AF Atmaca</name></author><author><name sortKey="Akbulut, Z" uniqKey="Akbulut Z">Z Akbulut</name></author><author><name sortKey="Demirci, A" uniqKey="Demirci A">A Demirci</name></author><author><name sortKey="Belenli, O" uniqKey="Belenli O">O Belenli</name></author><author><name sortKey="Alici, S" uniqKey="Alici S">S Alici</name></author><author><name sortKey="Balbay, Dm" uniqKey="Balbay D">DM Balbay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krathen, Ra" uniqKey="Krathen R">RA Krathen</name></author><author><name sortKey="Orengo, If" uniqKey="Orengo I">IF Orengo</name></author><author><name sortKey="Rosen, T" uniqKey="Rosen T">T Rosen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Block, Ca" uniqKey="Block C">CA Block</name></author><author><name sortKey="Dahmoush, L" uniqKey="Dahmoush L">L Dahmoush</name></author><author><name sortKey="Konety, Br" uniqKey="Konety B">BR Konety</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Narayana, Ma" uniqKey="Narayana M">MA Narayana</name></author><author><name sortKey="Patnayak, R" uniqKey="Patnayak R">R Patnayak</name></author><author><name sortKey="Rukmangadha, N" uniqKey="Rukmangadha N">N Rukmangadha</name></author><author><name sortKey="Chowhan, Ak" uniqKey="Chowhan A">AK Chowhan</name></author><author><name sortKey="Kottu, R" uniqKey="Kottu R">R Kottu</name></author><author><name sortKey="Phaneendra, Bv" uniqKey="Phaneendra B">BV Phaneendra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brownstein, Mh" uniqKey="Brownstein M">MH Brownstein</name></author><author><name sortKey="Helwig, Eb" uniqKey="Helwig E">EB Helwig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ando, K" uniqKey="Ando K">K Ando</name></author><author><name sortKey="Goto, Y" uniqKey="Goto Y">Y Goto</name></author><author><name sortKey="Kato, K" uniqKey="Kato K">K Kato</name></author><author><name sortKey="Murase, T" uniqKey="Murase T">T Murase</name></author><author><name sortKey="Matsumoto, Y" uniqKey="Matsumoto Y">Y Matsumoto</name></author><author><name sortKey="Ohashi, M" uniqKey="Ohashi M">M Ohashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Somani, Bk" uniqKey="Somani B">BK Somani</name></author><author><name sortKey="Prita, D" uniqKey="Prita D">D Prita</name></author><author><name sortKey="Grant, S" uniqKey="Grant S">S Grant</name></author><author><name sortKey="Nabi, G" uniqKey="Nabi G">G Nabi</name></author><author><name sortKey="N Ow, J" uniqKey="N Ow J">J N’Dow</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jaworsky, C" uniqKey="Jaworsky C">C Jaworsky</name></author><author><name sortKey="Bergfeld, Wf" uniqKey="Bergfeld W">WF Bergfeld</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Np" uniqKey="Wang N">NP Wang</name></author><author><name sortKey="Zee, S" uniqKey="Zee S">S Zee</name></author><author><name sortKey="Zarbo, Rj" uniqKey="Zarbo R">RJ Zarbo</name></author><author><name sortKey="Bacchi, Ce" uniqKey="Bacchi C">CE Bacchi</name></author><author><name sortKey="Gown, Am" uniqKey="Gown A">AM Gown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gowardhan, B" uniqKey="Gowardhan B">B Gowardhan</name></author><author><name sortKey="Mathers, Me" uniqKey="Mathers M">ME Mathers</name></author><author><name sortKey="Feggetter, Jg" uniqKey="Feggetter J">JG Feggetter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Salemis, Ns" uniqKey="Salemis N">NS Salemis</name></author><author><name sortKey="Gakis, C" uniqKey="Gakis C">C Gakis</name></author><author><name sortKey="Zografidis, A" uniqKey="Zografidis A">A Zografidis</name></author><author><name sortKey="Gourgiotis, S" uniqKey="Gourgiotis S">S Gourgiotis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Otto, T" uniqKey="Otto T">T Otto</name></author><author><name sortKey="Krege, S" uniqKey="Krege S">S Krege</name></author><author><name sortKey="Suhr, J" uniqKey="Suhr J">J Suhr</name></author><author><name sortKey="Rubben, H" uniqKey="Rubben H">H Rubben</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="case-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Med Case Rep</journal-id><journal-id journal-id-type="iso-abbrev">J Med Case Rep</journal-id><journal-title-group><journal-title>Journal of Medical Case Reports</journal-title></journal-title-group><issn pub-type="epub">1752-1947</issn><publisher><publisher-name>BioMed Central</publisher-name><publisher-loc>London</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25943325</article-id><article-id pub-id-type="pmc">4427993</article-id><article-id pub-id-type="publisher-id">585</article-id><article-id pub-id-type="doi">10.1186/s13256-015-0585-9</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Cutaneous metastasis of transitional cell carcinoma of the urinary bladder eight years after the primary: a case report</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Lees</surname><given-names>Andrea Nicole</given-names></name><address><email>andrea.lees@dhhs.tas.gov.au</email></address><xref ref-type="aff" rid="Aff1"></xref></contrib><aff id="Aff1">Royal Hobart Hospital, 48 Liverpool Street, Hobart, Tasmania 7000 Australia</aff></contrib-group><pub-date pub-type="epub"><day>6</day><month>5</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>6</day><month>5</month><year>2015</year></pub-date><pub-date pub-type="collection"><year>2015</year></pub-date><volume>9</volume><elocation-id>102</elocation-id><history><date date-type="received"><day>28</day><month>11</month><year>2014</year></date><date date-type="accepted"><day>2</day><month>4</month><year>2015</year></date></history><permissions><copyright-statement>© Lees; licensee BioMed Central. 2015</copyright-statement><license license-type="open-access"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0">http://creativecommons.org/licenses/by/4.0</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>) applies to the data made available in this article, unless otherwise stated.</license-p></license></permissions><abstract id="Abs1"><sec><title>Introduction</title><p>Cutaneous metastasis of bladder carcinoma is extremely rare with a limited number of published cases. An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis, as it can occur months or rarely as in this case, even years, after the primary cancer.</p></sec><sec><title>Case presentation</title><p>An 81-year-old Caucasian man presented with a one-year history of increasing left leg swelling and a two-month history of a macular-nodular rash on the anterior thigh, on a background of a high-grade (WHO Grade 2 of 3) papillary and invasive transitional cell carcinoma of the bladder in 2006. Following investigations, he was diagnosed as having probable locoregional recurrence of previously resected urothelial cancer of the bladder with extensive retrograde lymphatic permeation into the left thigh with cutaneous eruptions of malignancy. He completed a planned course of palliative radiation therapy to the left thigh lesions (30Gy divided over 10 fractions) as well as the left pelvic node (a total dose of 18Gy divided over six fractions). The disease ran an aggressive course and our patient died six months after the diagnosis of cutaneous metastases.</p></sec><sec><title>Conclusions</title><p>Metastatic disease should always be considered in the differential diagnosis in patients with a previous history of bladder cancer who present with cutaneous nodules, even many years after the initial diagnosis at the primary site.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>Cutaneous</kwd><kwd>Metastases</kwd><kwd>Transitional cell</kwd><kwd>Bladder</kwd><kwd>Urothelial</kwd><kwd>Cancer</kwd><kwd>Carcinoma</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>issue-copyright-statement</meta-name><meta-value>© The Author(s) 2015</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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