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Recurrent Hemorrhagic Pericardial Effusion and Tamponade due to Filariasis Successfully Treated with Ivermectin and Albendazole

Identifieur interne : 000185 ( Pmc/Curation ); précédent : 000184; suivant : 000186

Recurrent Hemorrhagic Pericardial Effusion and Tamponade due to Filariasis Successfully Treated with Ivermectin and Albendazole

Auteurs : Santosh Kumar Sinha [Inde] ; Amit Goel [Inde] ; Mohit Sachan [Inde] ; Sameer Saraf [Inde] ; Chandra Mohan Verma [Inde]

Source :

RBID : PMC:4485202

Abstract

Filariasis presenting with pericardial effusion with tamponade is rare. We report a case of a 30-year-old female who was admitted with severe dyspnea and chest pain since 2 days. Echocardiogram showed massive pericardial effusion with tamponade. Pericardial fluid aspiration drained 1.2 L of hemorrhagic fluid. Cytology examination revealed microfilaria of Wuchereria bancrofti. She was treated with diethyl carbamazine and discharged. Six weeks later, she presented again with massive pericardial effusion with cardiac tamponade. Pericardiocentesis was done. Cytology examination revealed microfilaria of W. bancrofti. This time she was treated with ivermectin and albendazole and cured. Hemorrhagic effusion resolved completely. Though relatively uncommon, tropical diseases must always be considered in the etiological diagnosis of recurrent pericardial effusion.


Url:
DOI: 10.4103/1995-705X.159220
PubMed: 26240733
PubMed Central: 4485202

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PMC:4485202

Le document en format XML

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<p>Filariasis presenting with pericardial effusion with tamponade is rare. We report a case of a 30-year-old female who was admitted with severe dyspnea and chest pain since 2 days. Echocardiogram showed massive pericardial effusion with tamponade. Pericardial fluid aspiration drained 1.2 L of hemorrhagic fluid. Cytology examination revealed microfilaria of
<italic>Wuchereria bancrofti</italic>
. She was treated with diethyl carbamazine and discharged. Six weeks later, she presented again with massive pericardial effusion with cardiac tamponade. Pericardiocentesis was done. Cytology examination revealed microfilaria of
<italic>W. bancrofti</italic>
. This time she was treated with ivermectin and albendazole and cured. Hemorrhagic effusion resolved completely. Though relatively uncommon, tropical diseases must always be considered in the etiological diagnosis of recurrent pericardial effusion.</p>
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<name sortKey="Verma, Sk" uniqKey="Verma S">SK Verma</name>
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<name sortKey="Ghodeswar, Ss" uniqKey="Ghodeswar S">SS Ghodeswar</name>
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<name sortKey="Chowdhary, M" uniqKey="Chowdhary M">M Chowdhary</name>
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<name sortKey="Langer, S" uniqKey="Langer S">S Langer</name>
</author>
<author>
<name sortKey="Aggarwal, M" uniqKey="Aggarwal M">M Aggarwal</name>
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<name sortKey="Agarwal, C" uniqKey="Agarwal C">C Agarwal</name>
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<name sortKey="Reddy, Gs" uniqKey="Reddy G">GS Reddy</name>
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<name sortKey="Balasundaram, S" uniqKey="Balasundaram S">S Balasundaram</name>
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<journal-id journal-id-type="nlm-ta">Heart Views</journal-id>
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<subject>Case Report</subject>
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<contrib contrib-type="author">
<name>
<surname>Sinha</surname>
<given-names>Santosh Kumar</given-names>
</name>
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<name>
<surname>Goel</surname>
<given-names>Amit</given-names>
</name>
<xref ref-type="aff" rid="aff1"></xref>
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<name>
<surname>Sachan</surname>
<given-names>Mohit</given-names>
</name>
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<name>
<surname>Saraf</surname>
<given-names>Sameer</given-names>
</name>
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<name>
<surname>Verma</surname>
<given-names>Chandra Mohan</given-names>
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<aff id="aff1">GSVM Medical College, Kanpur, Uttar Pradesh, India</aff>
<author-notes>
<corresp id="cor1">
<bold>Address for correspondence:</bold>
Dr. Santosh Kumar Sinha, 4 Prabhu Bandana Apartment 9/62 Arya Nagar, Kanpur, Uttar Pradesh - 208 002, India. E-mail:
<email xlink:href="fionasan@rediffmail.com">fionasan@rediffmail.com</email>
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<pub-date pub-type="ppub">
<season>Apr-Jun</season>
<year>2015</year>
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<volume>16</volume>
<issue>2</issue>
<fpage>53</fpage>
<lpage>55</lpage>
<permissions>
<copyright-statement>Copyright: © Gulf Heart Association 2015.</copyright-statement>
<copyright-year>2015</copyright-year>
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<abstract>
<p>Filariasis presenting with pericardial effusion with tamponade is rare. We report a case of a 30-year-old female who was admitted with severe dyspnea and chest pain since 2 days. Echocardiogram showed massive pericardial effusion with tamponade. Pericardial fluid aspiration drained 1.2 L of hemorrhagic fluid. Cytology examination revealed microfilaria of
<italic>Wuchereria bancrofti</italic>
. She was treated with diethyl carbamazine and discharged. Six weeks later, she presented again with massive pericardial effusion with cardiac tamponade. Pericardiocentesis was done. Cytology examination revealed microfilaria of
<italic>W. bancrofti</italic>
. This time she was treated with ivermectin and albendazole and cured. Hemorrhagic effusion resolved completely. Though relatively uncommon, tropical diseases must always be considered in the etiological diagnosis of recurrent pericardial effusion.</p>
</abstract>
<kwd-group>
<kwd>Albendazole</kwd>
<kwd>diethyl carbamazine</kwd>
<kwd>ivermectin</kwd>
<kwd>pericardial effusion with tamponade</kwd>
<kwd>
<italic>Wuchereria bancrofti</italic>
</kwd>
</kwd-group>
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