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<title xml:lang="en">Disseminated Microfilaremia Associated with Lung Cyst and Empyema: An Autopsy Report</title>
<author>
<name sortKey="Gupta, Kirti" sort="Gupta, Kirti" uniqKey="Gupta K" first="Kirti" last="Gupta">Kirti Gupta</name>
<affiliation>
<nlm:aff id="A1">Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Saikia, Uma Nahar" sort="Saikia, Uma Nahar" uniqKey="Saikia U" first="Uma Nahar" last="Saikia">Uma Nahar Saikia</name>
<affiliation>
<nlm:aff id="A1">Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bhatia, Prateek" sort="Bhatia, Prateek" uniqKey="Bhatia P" first="Prateek" last="Bhatia">Prateek Bhatia</name>
<affiliation>
<nlm:aff id="A1">Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Garg, Mandeep" sort="Garg, Mandeep" uniqKey="Garg M" first="Mandeep" last="Garg">Mandeep Garg</name>
<affiliation>
<nlm:aff id="A2">Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wanchu, Ajay" sort="Wanchu, Ajay" uniqKey="Wanchu A" first="Ajay" last="Wanchu">Ajay Wanchu</name>
<affiliation>
<nlm:aff id="A3">Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
</titleStmt>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">19290091</idno>
<idno type="pmc">2655342</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655342</idno>
<idno type="RBID">PMC:2655342</idno>
<idno type="doi">10.3347/kjp.2009.47.1.49</idno>
<date when="2009">2009</date>
<idno type="wicri:Area/Pmc/Corpus">004C03</idno>
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<title xml:lang="en" level="a" type="main">Disseminated Microfilaremia Associated with Lung Cyst and Empyema: An Autopsy Report</title>
<author>
<name sortKey="Gupta, Kirti" sort="Gupta, Kirti" uniqKey="Gupta K" first="Kirti" last="Gupta">Kirti Gupta</name>
<affiliation>
<nlm:aff id="A1">Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Saikia, Uma Nahar" sort="Saikia, Uma Nahar" uniqKey="Saikia U" first="Uma Nahar" last="Saikia">Uma Nahar Saikia</name>
<affiliation>
<nlm:aff id="A1">Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Bhatia, Prateek" sort="Bhatia, Prateek" uniqKey="Bhatia P" first="Prateek" last="Bhatia">Prateek Bhatia</name>
<affiliation>
<nlm:aff id="A1">Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Garg, Mandeep" sort="Garg, Mandeep" uniqKey="Garg M" first="Mandeep" last="Garg">Mandeep Garg</name>
<affiliation>
<nlm:aff id="A2">Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wanchu, Ajay" sort="Wanchu, Ajay" uniqKey="Wanchu A" first="Ajay" last="Wanchu">Ajay Wanchu</name>
<affiliation>
<nlm:aff id="A3">Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">The Korean Journal of Parasitology</title>
<idno type="ISSN">0023-4001</idno>
<idno type="eISSN">1738-0006</idno>
<imprint>
<date when="2009">2009</date>
</imprint>
</series>
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<textClass></textClass>
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<front>
<div type="abstract" xml:lang="en">
<p>Clinical manifestations of extralymphatic disease caused by filariasis are varied and range from symptoms due to tropical pulmonary eosinophilia to hematuria, proteinuria, splenomegaly, and rarely arthritis. Disseminated microfilaremia in association with loculated lung cyst and empyema is of rare occurrence and to the best of our knowledge has not been documented in the literature so far. We report here a case of disseminated microfilaremia due to
<italic>Wuchereria bancrofti</italic>
infection accompanied by a lung cyst and empyema in a 21-year-old Indian man.</p>
</div>
</front>
</TEI>
<pmc xml:lang="EN" article-type="case-report">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Korean J Parasitol</journal-id>
<journal-id journal-id-type="publisher-id">KJP</journal-id>
<journal-title>The Korean Journal of Parasitology</journal-title>
<issn pub-type="ppub">0023-4001</issn>
<issn pub-type="epub">1738-0006</issn>
<publisher>
<publisher-name>The Korean Society for Parasitology</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">19290091</article-id>
<article-id pub-id-type="pmc">2655342</article-id>
<article-id pub-id-type="doi">10.3347/kjp.2009.47.1.49</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Disseminated Microfilaremia Associated with Lung Cyst and Empyema: An Autopsy Report</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Gupta</surname>
<given-names>Kirti</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Saikia</surname>
<given-names>Uma Nahar</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bhatia</surname>
<given-names>Prateek</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Garg</surname>
<given-names>Mandeep</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Wanchu</surname>
<given-names>Ajay</given-names>
</name>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
Department of Histopathology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</aff>
<aff id="A2">
<label>2</label>
Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</aff>
<aff id="A3">
<label>3</label>
Department of Internal Medicine, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.</aff>
<author-notes>
<corresp>Corresponding author (
<email>kirti10gupta@gmail.com</email>
)</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>3</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="epub">
<day>12</day>
<month>3</month>
<year>2009</year>
</pub-date>
<volume>47</volume>
<issue>1</issue>
<fpage>49</fpage>
<lpage>52</lpage>
<history>
<date date-type="received">
<day>29</day>
<month>10</month>
<year>2008</year>
</date>
<date date-type="rev-recd">
<day>15</day>
<month>1</month>
<year>2009</year>
</date>
<date date-type="accepted">
<day>22</day>
<month>1</month>
<year>2009</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright © 2009 by The Korean Society for Parasitology</copyright-statement>
<copyright-year>2009</copyright-year>
</permissions>
<abstract>
<p>Clinical manifestations of extralymphatic disease caused by filariasis are varied and range from symptoms due to tropical pulmonary eosinophilia to hematuria, proteinuria, splenomegaly, and rarely arthritis. Disseminated microfilaremia in association with loculated lung cyst and empyema is of rare occurrence and to the best of our knowledge has not been documented in the literature so far. We report here a case of disseminated microfilaremia due to
<italic>Wuchereria bancrofti</italic>
infection accompanied by a lung cyst and empyema in a 21-year-old Indian man.</p>
</abstract>
<kwd-group>
<kwd>
<italic>Wuchereria bancrofti</italic>
</kwd>
<kwd>filariasis</kwd>
<kwd>microfilaria</kwd>
<kwd>extralymphatic manifestations</kwd>
</kwd-group>
</article-meta>
</front>
<floats-wrap>
<fig id="F1" position="float">
<label>Fig. 1</label>
<caption>
<p>(A) An oblique sonogram of the chest revealing a large multi-septate cystic collection in the left pleural cavity. (B) The left lung showing a large multi-loculated pleural based cyst. (C) Acute inflammatory infiltrates rich in eosinophils in the lumen and wall of the cyst (H-E, ×100). (D) Microfilariae of
<italic>Wuchereria bancrofti</italic>
present in the cystic wall (H-E, ×200). (E) Eosinophil rich inflammatory infiltrates along with fibrin filling the alveoli and the alveolar septae (H-E, ×100).</p>
</caption>
<graphic xlink:href="kjp-47-49-g001"></graphic>
</fig>
<fig id="F2" position="float">
<label>Fig. 2</label>
<caption>
<p>(A) Two testes with tiny, whitish nodules (1-2 mm) (arrow) along the length of the spermatic cord. (B) A live adult gravid female worm within the dilated lymphatic vessels (H-E, ×40). (C) Many sheathed microfilariae present within the gravid female worm (H-E, ×200). (D) Microfilariae present in the centre of necrotic foci within the hepatocytic lobule (H-E, ×200). (E) Microfilariae entrapped within the glomerular capillaries (H-E, ×200).</p>
</caption>
<graphic xlink:href="kjp-47-49-g002"></graphic>
</fig>
</floats-wrap>
</pmc>
</record>

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