Serveur d'exploration sur le lymphœdème

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<title xml:lang="en">Development of the mammalian lymphatic vasculature</title>
<author>
<name sortKey="Yang, Ying" sort="Yang, Ying" uniqKey="Yang Y" first="Ying" last="Yang">Ying Yang</name>
</author>
<author>
<name sortKey="Oliver, Guillermo" sort="Oliver, Guillermo" uniqKey="Oliver G" first="Guillermo" last="Oliver">Guillermo Oliver</name>
</author>
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<idno type="pmid">24590273</idno>
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<idno type="RBID">PMC:3938267</idno>
<idno type="doi">10.1172/JCI71609</idno>
<date when="2014">2014</date>
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<title xml:lang="en" level="a" type="main">Development of the mammalian lymphatic vasculature</title>
<author>
<name sortKey="Yang, Ying" sort="Yang, Ying" uniqKey="Yang Y" first="Ying" last="Yang">Ying Yang</name>
</author>
<author>
<name sortKey="Oliver, Guillermo" sort="Oliver, Guillermo" uniqKey="Oliver G" first="Guillermo" last="Oliver">Guillermo Oliver</name>
</author>
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<series>
<title level="j">The Journal of Clinical Investigation</title>
<idno type="ISSN">0021-9738</idno>
<idno type="eISSN">1558-8238</idno>
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<date when="2014">2014</date>
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<div type="abstract" xml:lang="en">
<p>The two vascular systems of our body are the blood and lymphatic vasculature. Our understanding of the cellular and molecular processes controlling the development of the lymphatic vasculature has progressed significantly in the last decade. In mammals, this is a stepwise process that starts in the embryonic veins, where lymphatic EC (LEC) progenitors are initially specified. The differentiation and maturation of these progenitors continues as they bud from the veins to produce scattered primitive lymph sacs, from which most of the lymphatic vasculature is derived. Here, we summarize our current understanding of the key steps leading to the formation of a functional lymphatic vasculature.</p>
</div>
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<pmc article-type="review-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Clin Invest</journal-id>
<journal-id journal-id-type="iso-abbrev">J. Clin. Invest</journal-id>
<journal-id journal-id-type="publisher-id">J CLIN INVEST</journal-id>
<journal-title-group>
<journal-title>The Journal of Clinical Investigation</journal-title>
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<issn pub-type="ppub">0021-9738</issn>
<issn pub-type="epub">1558-8238</issn>
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<publisher-name>American Society for Clinical Investigation</publisher-name>
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<article-id pub-id-type="pmid">24590273</article-id>
<article-id pub-id-type="pmc">3938267</article-id>
<article-id pub-id-type="publisher-id">71609</article-id>
<article-id pub-id-type="doi">10.1172/JCI71609</article-id>
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<article-title>Development of the mammalian lymphatic vasculature</article-title>
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<name>
<surname>Yang</surname>
<given-names>Ying</given-names>
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<name>
<surname>Oliver</surname>
<given-names>Guillermo</given-names>
</name>
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</contrib-group>
<aff id="JCI71609">Department of Genetics, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA.</aff>
<author-notes>
<corresp>Address correspondence to: Guillermo Oliver, Department of Genetics, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, Memphis, Tennessee 38105, USA. Phone: 901.595.2697; Fax: 901.595.6035; E-mail:
<email>guillermo.oliver@stjude.org</email>
. </corresp>
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<pub-date pub-type="epub">
<day>3</day>
<month>3</month>
<year>2014</year>
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<pub-date pub-type="ppub">
<day>3</day>
<month>3</month>
<year>2014</year>
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<pub-date pub-type="pmc-release">
<day>1</day>
<month>1</month>
<year>2015</year>
</pub-date>
<pmc-comment> PMC Release delay is 9 months and 29 days and was based on the . </pmc-comment>
<volume>124</volume>
<issue>3</issue>
<fpage>888</fpage>
<lpage>897</lpage>
<permissions>
<copyright-statement>Copyright © 2014, American Society for Clinical Investigation</copyright-statement>
<copyright-year>2014</copyright-year>
</permissions>
<abstract>
<p>The two vascular systems of our body are the blood and lymphatic vasculature. Our understanding of the cellular and molecular processes controlling the development of the lymphatic vasculature has progressed significantly in the last decade. In mammals, this is a stepwise process that starts in the embryonic veins, where lymphatic EC (LEC) progenitors are initially specified. The differentiation and maturation of these progenitors continues as they bud from the veins to produce scattered primitive lymph sacs, from which most of the lymphatic vasculature is derived. Here, we summarize our current understanding of the key steps leading to the formation of a functional lymphatic vasculature.</p>
</abstract>
</article-meta>
</front>
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