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<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Recent Advancement on Surgical Treatments for Lymphedema</title>
<author>
<name sortKey="Koshima, Isao" sort="Koshima, Isao" uniqKey="Koshima I" first="Isao" last="Koshima">Isao Koshima</name>
</author>
<author>
<name sortKey="Narushima, Mitsunaga" sort="Narushima, Mitsunaga" uniqKey="Narushima M" first="Mitsunaga" last="Narushima">Mitsunaga Narushima</name>
</author>
<author>
<name sortKey="Yamamoto, Yusuke" sort="Yamamoto, Yusuke" uniqKey="Yamamoto Y" first="Yusuke" last="Yamamoto">Yusuke Yamamoto</name>
</author>
<author>
<name sortKey="Mihara, Makoto" sort="Mihara, Makoto" uniqKey="Mihara M" first="Makoto" last="Mihara">Makoto Mihara</name>
</author>
<author>
<name sortKey="Iida, Takuya" sort="Iida, Takuya" uniqKey="Iida T" first="Takuya" last="Iida">Takuya Iida</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">23641262</idno>
<idno type="pmc">3641538</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641538</idno>
<idno type="RBID">PMC:3641538</idno>
<idno type="doi">10.3400/avd.ra.12.00080</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">004754</idno>
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<title xml:lang="en" level="a" type="main">Recent Advancement on Surgical Treatments for Lymphedema</title>
<author>
<name sortKey="Koshima, Isao" sort="Koshima, Isao" uniqKey="Koshima I" first="Isao" last="Koshima">Isao Koshima</name>
</author>
<author>
<name sortKey="Narushima, Mitsunaga" sort="Narushima, Mitsunaga" uniqKey="Narushima M" first="Mitsunaga" last="Narushima">Mitsunaga Narushima</name>
</author>
<author>
<name sortKey="Yamamoto, Yusuke" sort="Yamamoto, Yusuke" uniqKey="Yamamoto Y" first="Yusuke" last="Yamamoto">Yusuke Yamamoto</name>
</author>
<author>
<name sortKey="Mihara, Makoto" sort="Mihara, Makoto" uniqKey="Mihara M" first="Makoto" last="Mihara">Makoto Mihara</name>
</author>
<author>
<name sortKey="Iida, Takuya" sort="Iida, Takuya" uniqKey="Iida T" first="Takuya" last="Iida">Takuya Iida</name>
</author>
</analytic>
<series>
<title level="j">Annals of Vascular Diseases</title>
<idno type="ISSN">1881-641X</idno>
<idno type="eISSN">1881-6428</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<profileDesc>
<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>Treatment for limb lymphedema is challenging. The recent development of the super-microsurgical technique has made lymphaticovenular (LV) anastomosis an easier and more accurate surgical method for lymphedema. A summary of our experience as well as recent developments in surgical treatments for lymphedema are described.</p>
<p>Methods and Results: Ultra-microstructural analysis demonstrated that dysfunction of the lymphatics in lymphedema was caused by the degeneration and incomplete regeneration of smooth muscle cells and valve insufficiency in the lymphatic channel. ICG and infrared ray examinations have been proposed as new means of assessment of lymphatic function. LV anastomosis is suitable for genital edema, arm edema with severe phlegmone with leg edema, and early stage leg edema. Although pre- and postoperative compression therapy is generally required for limb edema, some cases do not require postoperative compression due to remaining or regenerated smooth muscle cells. As new methods of treatment, the vascularized lymphadiposal flap has been effective for progressive cases with LV anastomosis. LV anastomosis is also effective for congenital chyloabdomen. (*English Translation of J Jpn Coll Angiol 2008; 48: 173–178.)</p>
</div>
</front>
</TEI>
<pmc article-type="review-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Ann Vasc Dis</journal-id>
<journal-id journal-id-type="iso-abbrev">Ann Vasc Dis</journal-id>
<journal-id journal-id-type="pmc">AVD</journal-id>
<journal-title-group>
<journal-title>Annals of Vascular Diseases</journal-title>
</journal-title-group>
<issn pub-type="ppub">1881-641X</issn>
<issn pub-type="epub">1881-6428</issn>
<publisher>
<publisher-name>The Editorial Committee of Annals of Vascular Diseases</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">23641262</article-id>
<article-id pub-id-type="pmc">3641538</article-id>
<article-id pub-id-type="publisher-id">avd.ra.12.00080</article-id>
<article-id pub-id-type="doi">10.3400/avd.ra.12.00080</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Recent Advancement on Surgical Treatments for Lymphedema</article-title>
<alt-title alt-title-type="left-running-head">Koshima I, et al.</alt-title>
<alt-title alt-title-type="right-running-head">Recent Advancement on Surgical Treatments for Lymphedema</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Koshima</surname>
<given-names>Isao</given-names>
</name>
<degrees>MD</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Narushima</surname>
<given-names>Mitsunaga</given-names>
</name>
<degrees>MD</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Yamamoto</surname>
<given-names>Yusuke</given-names>
</name>
<degrees>MD</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mihara</surname>
<given-names>Makoto</given-names>
</name>
<degrees>MD</degrees>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Iida</surname>
<given-names>Takuya</given-names>
</name>
<degrees>MD</degrees>
</contrib>
<aff id="aff1">
<italic>Plastic and Reconstructive Surgery, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan</italic>
</aff>
</contrib-group>
<author-notes>
<corresp>Corresponding author: Isao Koshima. Plastic and Reconstructive Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan, Tel: +81-3-5800-8777, Fax: +81-3-5800-8950</corresp>
<fn>
<p>E-mail:
<email xlink:href="mailto:koushimai-pla@h.u-tokyo.ac.jp">koushimai-pla@h.u-tokyo.ac.jp</email>
</p>
</fn>
</author-notes>
<pub-date pub-type="epub">
<day>30</day>
<month>11</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub">
<year>2012</year>
</pub-date>
<volume>5</volume>
<issue>4</issue>
<fpage>409</fpage>
<lpage>415</lpage>
<history>
<date date-type="received">
<day>7</day>
<month>9</month>
<year>2012</year>
</date>
<date date-type="accepted">
<day>8</day>
<month>9</month>
<year>2012</year>
</date>
</history>
<permissions>
<copyright-statement>©2012 Annals of Vascular Diseases</copyright-statement>
<copyright-year>2012</copyright-year>
</permissions>
<abstract>
<p>Treatment for limb lymphedema is challenging. The recent development of the super-microsurgical technique has made lymphaticovenular (LV) anastomosis an easier and more accurate surgical method for lymphedema. A summary of our experience as well as recent developments in surgical treatments for lymphedema are described.</p>
<p>Methods and Results: Ultra-microstructural analysis demonstrated that dysfunction of the lymphatics in lymphedema was caused by the degeneration and incomplete regeneration of smooth muscle cells and valve insufficiency in the lymphatic channel. ICG and infrared ray examinations have been proposed as new means of assessment of lymphatic function. LV anastomosis is suitable for genital edema, arm edema with severe phlegmone with leg edema, and early stage leg edema. Although pre- and postoperative compression therapy is generally required for limb edema, some cases do not require postoperative compression due to remaining or regenerated smooth muscle cells. As new methods of treatment, the vascularized lymphadiposal flap has been effective for progressive cases with LV anastomosis. LV anastomosis is also effective for congenital chyloabdomen. (*English Translation of J Jpn Coll Angiol 2008; 48: 173–178.)</p>
</abstract>
<kwd-group>
<title>Keywords</title>
<kwd>lymphedema</kwd>
<kwd>lymphatic channel</kwd>
<kwd>lymphaticovenous anastomosis</kwd>
<kwd>microsurgery</kwd>
<kwd>supra-microsurgery</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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