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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Idiopathic Lymphocele: A Possible Diagnosis for Infraclavicular Masses</title><author><name sortKey="G Es Junior, Adenauer Marinho De Oliveira" sort="G Es Junior, Adenauer Marinho De Oliveira" uniqKey="G Es Junior A" first="Adenauer Marinho De Oliveira" last="G Es Junior">Adenauer Marinho De Oliveira G Es Junior</name><affiliation><nlm:aff id="I1">Division of Vascular Surgery, Air Force Hospital of Belém, 3492 Almirante Barroso Avenue, 66613-710 Belém, PA, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="I2">Department of Surgery, University Center of Pará (CESUPA), 3775 Almirante Barroso Avenue, 66613-903 Belém, PA, Brazil</nlm:aff></affiliation></author><author><name sortKey="Jeha, Salim Abdon Haber" sort="Jeha, Salim Abdon Haber" uniqKey="Jeha S" first="Salim Abdon Haber" last="Jeha">Salim Abdon Haber Jeha</name><affiliation><nlm:aff id="I1">Division of Vascular Surgery, Air Force Hospital of Belém, 3492 Almirante Barroso Avenue, 66613-710 Belém, PA, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="I3">Health Sciences Institute, Federal University of Pará (UFPA), 1 Praça Camilo Salgado, 66050-060 Belém, PA, Brazil</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23008796</idno><idno type="pmc">3446650</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446650</idno><idno type="RBID">PMC:3446650</idno><idno type="doi">10.1155/2012/593028</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">003D21</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003D21</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Idiopathic Lymphocele: A Possible Diagnosis for Infraclavicular Masses</title><author><name sortKey="G Es Junior, Adenauer Marinho De Oliveira" sort="G Es Junior, Adenauer Marinho De Oliveira" uniqKey="G Es Junior A" first="Adenauer Marinho De Oliveira" last="G Es Junior">Adenauer Marinho De Oliveira G Es Junior</name><affiliation><nlm:aff id="I1">Division of Vascular Surgery, Air Force Hospital of Belém, 3492 Almirante Barroso Avenue, 66613-710 Belém, PA, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="I2">Department of Surgery, University Center of Pará (CESUPA), 3775 Almirante Barroso Avenue, 66613-903 Belém, PA, Brazil</nlm:aff></affiliation></author><author><name sortKey="Jeha, Salim Abdon Haber" sort="Jeha, Salim Abdon Haber" uniqKey="Jeha S" first="Salim Abdon Haber" last="Jeha">Salim Abdon Haber Jeha</name><affiliation><nlm:aff id="I1">Division of Vascular Surgery, Air Force Hospital of Belém, 3492 Almirante Barroso Avenue, 66613-710 Belém, PA, Brazil</nlm:aff></affiliation><affiliation><nlm:aff id="I3">Health Sciences Institute, Federal University of Pará (UFPA), 1 Praça Camilo Salgado, 66050-060 Belém, PA, Brazil</nlm:aff></affiliation></author></analytic><series><title level="j">Case Reports in Surgery</title><idno type="ISSN">2090-6900</idno><idno type="eISSN">2090-6919</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Lymphoceles are usually related to trauma or surgery, and its spontaneous development is rare. The aim of this paper is to report an uncommon case of idiopathic lymphocele located on the right infraclavicular region, in a female patient with no previous local trauma or surgery and unremarkable medical history. The diagnose was suggested by the tomographic aspect of the lesion and confirmed by ultrasound-guided fluid aspiration and cytological analysis. The authors also provide a brief review of the most important thing diagnostic features and treatment options for this condition. For the practicing clinician, the most important is to achieve an accurate diagnose and to choose the proper therapeutic method according to each clinical scenario.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Gomez, M" uniqKey="Gomez M">M Gomez</name></author><author><name sortKey="Tanner, Nt" uniqKey="Tanner N">NT Tanner</name></author><author><name sortKey="Recavarren, Ra" uniqKey="Recavarren R">RA Recavarren</name></author><author><name sortKey="Ravenel, J" uniqKey="Ravenel J">J Ravenel</name></author><author><name sortKey="Silvestri, Ga" uniqKey="Silvestri G">GA Silvestri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khwaja, Ha" uniqKey="Khwaja H">HA Khwaja</name></author><author><name sortKey="Chaudhry, Sm" uniqKey="Chaudhry S">SM Chaudhry</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Hy" uniqKey="Kim H">HY Kim</name></author><author><name sortKey="Kim, Jw" uniqKey="Kim J">JW Kim</name></author><author><name sortKey="Kim, Sh" uniqKey="Kim S">SH Kim</name></author><author><name sortKey="Kim, Yt" uniqKey="Kim Y">YT Kim</name></author><author><name sortKey="Kim, Jh" uniqKey="Kim J">JH Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, Dm" uniqKey="Yang D">DM Yang</name></author><author><name sortKey="Jung, Dh" uniqKey="Jung D">DH Jung</name></author><author><name sortKey="Kim, H" uniqKey="Kim H">H Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, J K" uniqKey="Kim J">J-K Kim</name></author><author><name sortKey="Jeong, Yy" uniqKey="Jeong Y">YY Jeong</name></author><author><name sortKey="Kim, Yh" uniqKey="Kim Y">YH Kim</name></author><author><name sortKey="Kim, Yc" uniqKey="Kim Y">YC Kim</name></author><author><name sortKey="Kang, Hk" uniqKey="Kang H">HK Kang</name></author><author><name sortKey="Choi, Hs" uniqKey="Choi H">HS Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pastore, M" uniqKey="Pastore M">M Pastore</name></author><author><name sortKey="Manci, N" uniqKey="Manci N">N Manci</name></author><author><name sortKey="Marchetti, C" uniqKey="Marchetti C">C Marchetti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zomorrodi, A" uniqKey="Zomorrodi A">A Zomorrodi</name></author><author><name sortKey="Buhluli, A" uniqKey="Buhluli A">A Buhluli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zargar Shoshtari, Ma" uniqKey="Zargar Shoshtari M">MA Zargar-Shoshtari</name></author><author><name sortKey="Soleimani, M" uniqKey="Soleimani M">M Soleimani</name></author><author><name sortKey="Salimi, H" uniqKey="Salimi H">H Salimi</name></author><author><name sortKey="Mehravaran, K" uniqKey="Mehravaran K">K Mehravaran</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gonzalez Gay, Ma" uniqKey="Gonzalez Gay M">MA González-Gay</name></author><author><name sortKey="Garcia Porrua, C" uniqKey="Garcia Porrua C">C García-Porrúa</name></author><author><name sortKey="Pulpeiro, Jr" uniqKey="Pulpeiro J">JR Pulpeiro</name></author><author><name sortKey="Bra As, F" uniqKey="Bra As F">F Brañas</name></author><author><name sortKey="Mateo Camb N, L" uniqKey="Mateo Camb N L">L Mateo-Cambón</name></author><author><name sortKey="Hernandez, T" uniqKey="Hernandez T">T Hernández</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Allen, Sj" uniqKey="Allen S">SJ Allen</name></author><author><name sortKey="Koch, Sm" uniqKey="Koch S">SM Koch</name></author><author><name sortKey="Tonnesen, As" uniqKey="Tonnesen A">AS Tonnesen</name></author><author><name sortKey="Bowman Howard, M" uniqKey="Bowman Howard M">M Bowman-Howard</name></author><author><name sortKey="Khalil, K" uniqKey="Khalil K">K Khalil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zuckerman, Da" uniqKey="Zuckerman D">DA Zuckerman</name></author><author><name sortKey="Yeager, Td" uniqKey="Yeager T">TD Yeager</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perusse, Kr" uniqKey="Perusse K">KR Perusse</name></author><author><name sortKey="Mcadams, Hp" uniqKey="Mcadams H">HP McAdams</name></author><author><name sortKey="Earls, Jp" uniqKey="Earls J">JP Earls</name></author><author><name sortKey="Peller, Pj" uniqKey="Peller P">PJ Peller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Metcalf, Ks" uniqKey="Metcalf K">KS Metcalf</name></author><author><name sortKey="Peel, Kr" uniqKey="Peel K">KR Peel</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Case Rep Surg</journal-id><journal-id journal-id-type="iso-abbrev">Case Rep Surg</journal-id><journal-id journal-id-type="publisher-id">CRIM.SURGERY</journal-id><journal-title-group><journal-title>Case Reports in Surgery</journal-title></journal-title-group><issn pub-type="ppub">2090-6900</issn><issn pub-type="epub">2090-6919</issn><publisher><publisher-name>Hindawi Publishing Corporation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23008796</article-id><article-id pub-id-type="pmc">3446650</article-id><article-id pub-id-type="doi">10.1155/2012/593028</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>Idiopathic Lymphocele: A Possible Diagnosis for Infraclavicular Masses</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Góes Junior</surname><given-names>Adenauer Marinho de Oliveira</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="aff" rid="I2"><sup>2</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Jeha</surname><given-names>Salim Abdon Haber</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="aff" rid="I3"><sup>3</sup></xref></contrib></contrib-group><aff id="I1"><sup>1</sup>Division of Vascular Surgery, Air Force Hospital of Belém, 3492 Almirante Barroso Avenue, 66613-710 Belém, PA, Brazil</aff><aff id="I2"><sup>2</sup>Department of Surgery, University Center of Pará (CESUPA), 3775 Almirante Barroso Avenue, 66613-903 Belém, PA, Brazil</aff><aff id="I3"><sup>3</sup>Health Sciences Institute, Federal University of Pará (UFPA), 1 Praça Camilo Salgado, 66050-060 Belém, PA, Brazil</aff><author-notes><corresp id="cor1">*Adenauer Marinho de Oliveira Góes Junior: <email>adenauer-junior@ibest.com.br</email></corresp><fn fn-type="other"><p>Academic Editors: C. Foroulis and O. Olsha</p></fn></author-notes><pub-date pub-type="ppub"><year>2012</year></pub-date><pub-date pub-type="epub"><day>11</day><month>9</month><year>2012</year></pub-date><volume>2012</volume><elocation-id>593028</elocation-id><history><date date-type="received"><day>4</day><month>4</month><year>2012</year></date><date date-type="accepted"><day>21</day><month>8</month><year>2012</year></date></history><permissions><copyright-statement>Copyright © 2012 A. M. O. Góes Junior and S. A. H. Jeha.</copyright-statement><copyright-year>2012</copyright-year><license xlink:href="https://creativecommons.org/licenses/by/3.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>Lymphoceles are usually related to trauma or surgery, and its spontaneous development is rare. The aim of this paper is to report an uncommon case of idiopathic lymphocele located on the right infraclavicular region, in a female patient with no previous local trauma or surgery and unremarkable medical history. The diagnose was suggested by the tomographic aspect of the lesion and confirmed by ultrasound-guided fluid aspiration and cytological analysis. The authors also provide a brief review of the most important thing diagnostic features and treatment options for this condition. For the practicing clinician, the most important is to achieve an accurate diagnose and to choose the proper therapeutic method according to each clinical scenario.</p></abstract></article-meta></front><body><sec id="sec1"><title>1. Introduction</title><p> A lymphocele, also referred to as chylous pseudocysts, cystic lymphangiomas, and lymphatic duct hygromas, is defined as a circumscribed collection of protein-rich lymphatic fluid without an epithelial lining that develops in anatomic compartments as the result of trauma or interruption to the lymphatic system [<xref rid="B1" ref-type="bibr">1</xref>–<xref rid="B4" ref-type="bibr">4</xref>].</p><p> Lymphocele formation is a described complication of surgery in and around the inguinal and femoral vessels [<xref rid="B1" ref-type="bibr">1</xref>], cardiothoracic surgery, blunt chest trauma [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B2" ref-type="bibr">2</xref>], gynecologic surgery [<xref rid="B3" ref-type="bibr">3</xref>, <xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B6" ref-type="bibr">6</xref>], esophagogastrectomy [<xref rid="B2" ref-type="bibr">2</xref>], renal transplant [<xref rid="B4" ref-type="bibr">4</xref>, <xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>, <xref rid="B8" ref-type="bibr">8</xref>], and prostatectomy [<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B9" ref-type="bibr">9</xref>] among others. Its spontaneous appearance, on the contrary, is an uncommon fact.</p><p> Currently, no diagnostic algorithm is in place for the evaluation of a suspected lymphocele, but numerous radiographic modalities when used in combination with clinical history and presentation will aid in the diagnose [<xref rid="B1" ref-type="bibr">1</xref>]. If imaging modalities provide uncertain diagnose, needle aspiration with cytologic [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B10" ref-type="bibr">10</xref>], and biochemical [<xref rid="B7" ref-type="bibr">7</xref>] analysis may be necessary for confirmation. </p><p> There is scarce information about the natural history of spontaneous lymphoceles, but it is established that those related to trauma/surgical procedures, when small, are usually asymptomatic and can reabsorb spontaneously [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B8" ref-type="bibr">8</xref>]; on the other hand, large collections, especially if compressing important structures or when infected, require more aggressive approaches, including fine-needle aspiration, sclerotherapy, catheter drainage, and surgery [<xref rid="B1" ref-type="bibr">1</xref>–<xref rid="B3" ref-type="bibr">3</xref>, <xref rid="B5" ref-type="bibr">5</xref>]. </p><p> The aim of this paper is to report a case of idiopathic infraclavicular lymphocele and review the most important diagnosis features and treatment options for this condition.</p></sec><sec id="sec2"><title>2. Case Presentation </title><p> Female, 54 years old, without previous noticed diseases, went to the dermatologist complaining about a “node” at the infraclavicular right region. The patient noted the lesions about 2 months before, denied systemic symptoms but referred antiaesthetic complains and local discomfort, caused by a “mass” effect. She also denied previous traumas or surgical procedures nearby the mentioned topography.</p><p> A soft tissue ultrasound revealed a cystic lesion attached to the subclavian vessels; the patient was referred to the vascular surgery team. A more detailed physical exam revealed a visible, well limited mass, painless, firmly fixed at the right infraclavicular region, without fremitus nor murmur, presenting a discreet pulsation (giving the impression of being transmitted from the subclavian artery).</p><p> A computerized tomography showed a cystic lesion, under the pectoral muscles, measuring approximately 8 × 3.8 cm, without enhance after intravascular contrast material was administered, on intimate contact to the subclavian vessels trough it's upper border (Figures <xref ref-type="fig" rid="fig1">1</xref>, <xref ref-type="fig" rid="fig2">2</xref> and <xref ref-type="fig" rid="fig3">3</xref>). The diagnose of lymphocele was suggested by the radiologist physician.</p><p> A fine-needle aspiration, guided by ultrasound was performed. On the application of suction, a clear yellow fluid was obtained. About 20 cc was removed. In spite of the fact that ultrasound examination pointed a remaining volume of approximately 5 cc, because of the proximity to the subclavian vessels and pleura (<xref ref-type="fig" rid="fig4">Figure 4</xref>) and the rising risks of iatrogenic damage as the cystic lesion became narrowed by aspiration, the procedure was interrupted.</p><p>Cytologic analysis of the fluid showed 100% of normal lymphocytes, confirming the diagnose of lymphocele.</p><p> A post-procedure thorax X-ray was obtained and documented no pneumo/hemothorax.</p><p>After the procedure the patient complained no more about the “mass” sensation and discomfort referred before the treatment. </p><p> After one month the patient remained without complaints and no mass was palpable at the infraclavicular right region. Because of the patient's lack of symptoms, she elected to forgo additional interventional procedures and be followed up clinically.</p></sec><sec id="sec3"><title>3. Discussion </title><p> The appearance of idiopathic lymphocele is uncommon and can be only speculated to be associated to lymphatic leakage due to a miss diagnosed minor trauma or repetitive effort injury; its diagnose, evolution, and management are, for this reason, thought to be similar to those that occur after traumatic injuries or surgical procedures. </p><p>Because lymphatic fluid is protein rich and devoid of platelets or clotting factors, a transected lymphatic channel cannot clot and is therefore prone to leakage [<xref rid="B1" ref-type="bibr">1</xref>]. A lymphocele may develop days to years after the injury [<xref rid="B1" ref-type="bibr">1</xref>]. The natural course of lymphoceles usually depends on its size and the presence of infection [<xref rid="B3" ref-type="bibr">3</xref>, <xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>]. When small, sterile and asymptomatic, the spontaneous resolution by reabsorption is possible [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B5" ref-type="bibr">5</xref>–<xref rid="B8" ref-type="bibr">8</xref>]. However, a few may enlarge and cause symptoms related to infection and compression, depending on the lymphocele location. If intrathoracic, for example, symptoms can include dysphagia, dyspnea or chest pain [<xref rid="B1" ref-type="bibr">1</xref>]. When located on the abdomen or pelvis, large lymphoceles may compress the bladder, ureter, rectosigmoid, liac vessels [<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>], vena cava, portal vein [<xref rid="B8" ref-type="bibr">8</xref>], and sacral plexus [<xref rid="B9" ref-type="bibr">9</xref>]. The compression of these structures can lead to abdominal distention, abdominal and pelvic pain, hidronefrosis, bladder disfunction, constipation, tenesmus [<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>] edema in the inguinal regions and genitalia, deterioration of a transplanted kidney, fever, lymphedema of the ipsilateral lower limb, compressive syndrome of the vena cava or the portal vein [<xref rid="B8" ref-type="bibr">8</xref>], thrombosis of iliac vessels [<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>], thrombophlebitis [<xref rid="B11" ref-type="bibr">11</xref>], and neuralgia [<xref rid="B9" ref-type="bibr">9</xref>]. It is also possible to find severe bilateral peripheral edema and pulmonary thromboembolism from intraluminal thrombus in the compressed inferior vena cava [<xref rid="B9" ref-type="bibr">9</xref>, <xref rid="B11" ref-type="bibr">11</xref>]. In the reported case, although the lymphocele had considerable volume and was located near the subclavian vessels and brachial plexus, the patient had no other symptom beside the discomfort caused by the “mass” sensation. </p><p> Lymphoceles constitute a diagnostic challenge [<xref rid="B1" ref-type="bibr">1</xref>], especially when there is no previous history of trauma or surgery, as happened in the reported case. </p><p> Currently, no diagnostic algorithm is in place for the evaluation of a suspected lymphocele [<xref rid="B1" ref-type="bibr">1</xref>]. The diagnosis hypothesis is based on a compatible history, symptoms such as the above described and a variety of radiological exams that help to exclude differential diagnosis such as hematomas, urinomas, seromas, lymphadenopathy, pseudoaneurysms, and abscesses among others. When image techniques are not conclusive or the differential diagnosis with other pathologies is imperative, needle aspiration with biochemical and cytologic analysis is often necessary. </p><p> Findings on ultrasound include a thin-walled collection [<xref rid="B9" ref-type="bibr">9</xref>] with the aspect of a hypoechoic or anechoic well-circumscribed oval structure [<xref rid="B3" ref-type="bibr">3</xref>]; occasional internal septa and debris can be also visualized [<xref rid="B1" ref-type="bibr">1</xref>].</p><p> The typical presentation on a chest radiograph includes a smooth focal mediastinal mass or mediastinal widening. These abnormalities typically prompt further evaluation with a chest computerized tomography (CT) scan [<xref rid="B1" ref-type="bibr">1</xref>].</p><p> CT scan features classically described for lymphoceles include a smooth, oval, or tubular mass with a thin wall that does not enhance after intravascular contrast material is administered, homogeneous attenuation, typically in the range of water and no infiltration of adjacent structures [<xref rid="B1" ref-type="bibr">1</xref>–<xref rid="B3" ref-type="bibr">3</xref>, <xref rid="B9" ref-type="bibr">9</xref>, <xref rid="B12" ref-type="bibr">12</xref>]. It is important to note that even though the attenuation is usually similar to water, this may alter depending on the chylomicron content [<xref rid="B2" ref-type="bibr">2</xref>] and that cysts containing nonserious fluid can have high attenuation on a CT scan and may be mistaken for solid lesions [<xref rid="B1" ref-type="bibr">1</xref>]. Calcification of the lymphocele wall may be seen on rare occasions [<xref rid="B4" ref-type="bibr">4</xref>, <xref rid="B13" ref-type="bibr">13</xref>].</p><p> Magnetic resonance imaging (MRI) features depend on the fluid chemical composition [<xref rid="B2" ref-type="bibr">2</xref>]. Lymphoceles contain proteinaceous fluid similar to extracellular fluid that results in a low T1-weighted intensity greater than water and a high T2-weighted intensity less than water. As the chylomicron content increases, however, there is a reversal of MRI findings with a high T1-weighted intensity and an intermediate T2-weighted intensity [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B2" ref-type="bibr">2</xref>]. MRI typical findings include thin-walled cystic collections, without contrast enhancement [<xref rid="B9" ref-type="bibr">9</xref>], nor evidence of flow, hemorrhage, or hemosiderin deposition [<xref rid="B12" ref-type="bibr">12</xref>].</p><p> Although some authors find MRI useful [<xref rid="B2" ref-type="bibr">2</xref>], others consider that, for the practicing clinician, the MRI does not provide any additional information to that obtained on the CT scan [<xref rid="B1" ref-type="bibr">1</xref>].</p><p> In obscure cases, additional investigations may be found helpful, and lymphangiography and lymphoscintigraphy can be considered [<xref rid="B13" ref-type="bibr">13</xref>]. Lymphoscintigraphy allows a two-dimensional visualization of the lymphatic network and is specially useful for evaluation of traumatic lymphoceles [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B12" ref-type="bibr">12</xref>]. Lymphography can be performed by contrast injection through needle or angiographic sheaths to evaluate the size of the lesion and the presence of internal septation. When found, septum can be broken using guide wires and fluoroscopic guidance with the intention to facilitate the aspiration or drainage of a greater volume of fluid [<xref rid="B5" ref-type="bibr">5</xref>]. </p><p> If the radiographic findings do not correlate or the patient is symptomatic, however, it may be necessary to perform needle aspiration of the fluid and cytologic analysis [<xref rid="B1" ref-type="bibr">1</xref>]. Fluid is typically described as straw colored [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B13" ref-type="bibr">13</xref>], milky color [<xref rid="B10" ref-type="bibr">10</xref>], clear and yellow in noninfected lesions and turbid, and gray in infected ones [<xref rid="B5" ref-type="bibr">5</xref>]. It contains erythrocytes, lymphocytes, and scant polymorphs [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B2" ref-type="bibr">2</xref>]. Among the white blood cells (WBCs) there is a predominance of lymphocytes [<xref rid="B5" ref-type="bibr">5</xref>] and a 70% lymphocytes of all WBC is characteristic of lymph [<xref rid="B10" ref-type="bibr">10</xref>]. Analysis of the fluid demonstrates high triglyceride levels [<xref rid="B1" ref-type="bibr">1</xref>], chylomicrons [<xref rid="B10" ref-type="bibr">10</xref>], and the same level of proteins, urea nitrogen, creatinine, electrolytes, and lipids as serum has [<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>].</p><p> Management varies with size, symptoms, and anatomical location. Options include observation, needle aspiration, surgical resection, internal drainage via open or laparoscopic/thoracoscopic marsupialization, and percutaneous external drainage with or without the addition of sclerosing agents [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B3" ref-type="bibr">3</xref>, <xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>, <xref rid="B13" ref-type="bibr">13</xref>]. For infected lymphoceles, antibiotics alone are often sufficient [<xref rid="B13" ref-type="bibr">13</xref>]. </p><p> Simple aspiration, preferentially under CT or ultrasound guidance, has been used successfully to treat lymphoceles and relieve pressure symptoms [<xref rid="B2" ref-type="bibr">2</xref>, <xref rid="B3" ref-type="bibr">3</xref>, <xref rid="B13" ref-type="bibr">13</xref>]. Needle aspiration has been reported as a safe and effective therapeutic alternative to surgery, and because of its minor morbidity some authors consider it as first-line treatment [<xref rid="B13" ref-type="bibr">13</xref>], but most studies report high recurrence rate of 80%–90%, which necessitates repeated aspirations and results in a 25–50% infection rate [<xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B7" ref-type="bibr">7</xref>, <xref rid="B13" ref-type="bibr">13</xref>]. In consequence, the use of needle aspiration once only would seem to be sensible [<xref rid="B13" ref-type="bibr">13</xref>]. Simple aspiration was first chosen in this case because the patient had an unremarkable medical history and no previous trauma or local surgery and the diagnose of a lymphocele was based only on the radiological aspect. Fluid aspiration, ergo, provided at the same time an opportunity to exclude differential diagnoses and relief the patient's symptoms. </p><p> Percutaneous catheter drainage has a mean duration of 14.5 days [<xref rid="B5" ref-type="bibr">5</xref>]; success rates of 79% to 82% with prolonged drainage have been reported [<xref rid="B7" ref-type="bibr">7</xref>], and for some authors success can be as high as 100% [<xref rid="B5" ref-type="bibr">5</xref>] even though a 63.6% rate of lymph reaccumulation has also been described [<xref rid="B8" ref-type="bibr">8</xref>]. Instillation of sclerosing agents through drainage catheter is an attractive alternative because of its lower reported recurrence rates and shorter duration of therapy than percutaneous drainage alone and because it is less invasive than surgery [<xref rid="B11" ref-type="bibr">11</xref>]. Tetracycline, ampicilin, povidone iodine, ethanol, doxycycline, and bleomycin [<xref rid="B1" ref-type="bibr">1</xref>, <xref rid="B5" ref-type="bibr">5</xref>, <xref rid="B11" ref-type="bibr">11</xref>] are among the reported sclerosing agents. Sclerotherapy usually results in a success rate of 79%–100% with duration from 9 to 36 days [<xref rid="B5" ref-type="bibr">5</xref>]. </p><p> Surgery has been considered the treatment of choice because of the rates of recurrence after percutaneous aspiration or drainage [<xref rid="B11" ref-type="bibr">11</xref>]. Surgical drainage achieves success in 50%–70% and peritoneal marsupialization is effective in more than 90%; however, these methods have some disadvantages, such as surgical morbidity and mortality, economic burden, and the need for long hospitalization [<xref rid="B5" ref-type="bibr">5</xref>].</p><p> Idiopathic lymphoceles are infrequently. If even diagnostic algorithm is not currently established, the same is applied for the therapeutic strategies. 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PM: pectoral muscle; L: lymphocele; RL: right lung.</p></caption><graphic xlink:href="CRIM.SURGERY2012-593028.001"></graphic></fig><fig id="fig2" orientation="portrait" position="float"><label>Figure 2</label><caption><p>Chest CT with intravascular contrast, sagital view. PM: pectoral muscle; L: lymphocele; RL: right lung; SCV: subclavian vessels.</p></caption><graphic xlink:href="CRIM.SURGERY2012-593028.002"></graphic></fig><fig id="fig3" orientation="portrait" position="float"><label>Figure 3</label><caption><p>Chest CT with intravascular contrast, coronal view. L: lymphocele; RL: right lung; SCV: subclavian vessels.</p></caption><graphic xlink:href="CRIM.SURGERY2012-593028.003"></graphic></fig><fig id="fig4" orientation="portrait" position="float"><label>Figure 4</label><caption><p>Color doppler ultrasound, axial view. PM: pectoral muscle; L: lymphocele; RL: right lung; SCV: subclavian vessels.</p></caption><graphic xlink:href="CRIM.SURGERY2012-593028.004"></graphic></fig></floats-group></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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