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<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">The Impact of Secondary Lymphedema after Head and Neck Cancer Treatment on Symptoms, Functional Status, and Quality Of Life</title>
<author>
<name sortKey="Deng, Jie" sort="Deng, Jie" uniqKey="Deng J" first="Jie" last="Deng">Jie Deng</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Murphy, Barbara A" sort="Murphy, Barbara A" uniqKey="Murphy B" first="Barbara A." last="Murphy">Barbara A. Murphy</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Dietrich, Mary S" sort="Dietrich, Mary S" uniqKey="Dietrich M" first="Mary S." last="Dietrich">Mary S. Dietrich</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A3">Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wells, Nancy" sort="Wells, Nancy" uniqKey="Wells N" first="Nancy" last="Wells">Nancy Wells</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wallston, Kenneth A" sort="Wallston, Kenneth A" uniqKey="Wallston K" first="Kenneth A." last="Wallston">Kenneth A. Wallston</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Sinard, Robert J" sort="Sinard, Robert J" uniqKey="Sinard R" first="Robert J." last="Sinard">Robert J. Sinard</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cmelak, Anthony J" sort="Cmelak, Anthony J" uniqKey="Cmelak A" first="Anthony J." last="Cmelak">Anthony J. Cmelak</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Gilbert, Jill" sort="Gilbert, Jill" uniqKey="Gilbert J" first="Jill" last="Gilbert">Jill Gilbert</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ridner, Sheila H" sort="Ridner, Sheila H" uniqKey="Ridner S" first="Sheila H." last="Ridner">Sheila H. Ridner</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
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<idno type="pmid">22791550</idno>
<idno type="pmc">4017911</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017911</idno>
<idno type="RBID">PMC:4017911</idno>
<idno type="doi">10.1002/hed.23084</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">003863</idno>
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<analytic>
<title xml:lang="en" level="a" type="main">The Impact of Secondary Lymphedema after Head and Neck Cancer Treatment on Symptoms, Functional Status, and Quality Of Life</title>
<author>
<name sortKey="Deng, Jie" sort="Deng, Jie" uniqKey="Deng J" first="Jie" last="Deng">Jie Deng</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Murphy, Barbara A" sort="Murphy, Barbara A" uniqKey="Murphy B" first="Barbara A." last="Murphy">Barbara A. Murphy</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Dietrich, Mary S" sort="Dietrich, Mary S" uniqKey="Dietrich M" first="Mary S." last="Dietrich">Mary S. Dietrich</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A3">Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wells, Nancy" sort="Wells, Nancy" uniqKey="Wells N" first="Nancy" last="Wells">Nancy Wells</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wallston, Kenneth A" sort="Wallston, Kenneth A" uniqKey="Wallston K" first="Kenneth A." last="Wallston">Kenneth A. Wallston</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Sinard, Robert J" sort="Sinard, Robert J" uniqKey="Sinard R" first="Robert J." last="Sinard">Robert J. Sinard</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Cmelak, Anthony J" sort="Cmelak, Anthony J" uniqKey="Cmelak A" first="Anthony J." last="Cmelak">Anthony J. Cmelak</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Gilbert, Jill" sort="Gilbert, Jill" uniqKey="Gilbert J" first="Jill" last="Gilbert">Jill Gilbert</name>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ridner, Sheila H" sort="Ridner, Sheila H" uniqKey="Ridner S" first="Sheila H." last="Ridner">Sheila H. Ridner</name>
<affiliation>
<nlm:aff id="A1">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="A2">School of Nursing, Vanderbilt University, Nashville, TN</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Head & neck</title>
<idno type="ISSN">1043-3074</idno>
<idno type="eISSN">1097-0347</idno>
<imprint>
<date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec id="S1">
<title>Background</title>
<p id="P1">Lymphedema may disrupt local function and affect quality of life (QOL) in patients with head and neck cancer. The study aim was to examine the associations among severity of internal and external lymphedema, symptoms, functional status, and QOL in patients with head and neck cancer.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">The sample included 103 patients who were ≥3 months post head and neck cancer treatment. Variables assessed included severity of internal and external lymphedema, physical/psychological symptoms, functional status, and QOL.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Severity of internal and external lymphedema was associated with physical symptoms and psychological symptoms. Patients with more severe external lymphedema were more likely to have a decrease in neck left/right rotation. The combined effects of external and internal lymphedema severity were associated with hearing impairment and decreased QOL.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Lymphedema severity correlates with symptom burden, functional status, and QOL in patients post head and neck cancer treatment.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-journal-id">8902541</journal-id>
<journal-id journal-id-type="pubmed-jr-id">3967</journal-id>
<journal-id journal-id-type="nlm-ta">Head Neck</journal-id>
<journal-id journal-id-type="iso-abbrev">Head Neck</journal-id>
<journal-title-group>
<journal-title>Head & neck</journal-title>
</journal-title-group>
<issn pub-type="ppub">1043-3074</issn>
<issn pub-type="epub">1097-0347</issn>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">22791550</article-id>
<article-id pub-id-type="pmc">4017911</article-id>
<article-id pub-id-type="doi">10.1002/hed.23084</article-id>
<article-id pub-id-type="manuscript">NIHMS562463</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>The Impact of Secondary Lymphedema after Head and Neck Cancer Treatment on Symptoms, Functional Status, and Quality Of Life</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Deng</surname>
<given-names>Jie</given-names>
</name>
<degrees>PhD, RN</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Murphy</surname>
<given-names>Barbara A.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Dietrich</surname>
<given-names>Mary S.</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A2">2</xref>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Wells</surname>
<given-names>Nancy</given-names>
</name>
<degrees>DNSc, RN</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Wallston</surname>
<given-names>Kenneth A.</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Sinard</surname>
<given-names>Robert J.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Cmelak</surname>
<given-names>Anthony J.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gilbert</surname>
<given-names>Jill</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ridner</surname>
<given-names>Sheila H.</given-names>
</name>
<degrees>PhD, RN</degrees>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
</contrib-group>
<aff id="A1">
<label>1</label>
School of Nursing, Vanderbilt University, Nashville, TN</aff>
<aff id="A2">
<label>2</label>
School of Nursing, Vanderbilt University, Nashville, TN</aff>
<aff id="A3">
<label>3</label>
Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville TN</aff>
<author-notes>
<corresp id="cor1">Corresponding author: Jie Deng, PhD, Vanderbilt University School of Nursing, 461 21
<sup>st</sup>
Ave. South, GH 600B, Nashville, TN 37240; phone: 615-875-7713; fax: 615-343-5898;
<email>jie.deng@vanderbilt.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted">
<day>4</day>
<month>4</month>
<year>2014</year>
</pub-date>
<pub-date pub-type="epub">
<day>12</day>
<month>7</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub">
<month>7</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>01</day>
<month>7</month>
<year>2014</year>
</pub-date>
<volume>35</volume>
<issue>7</issue>
<fpage>1026</fpage>
<lpage>1035</lpage>
<pmc-comment>elocation-id from pubmed: 10.1002/hed.23084</pmc-comment>
<abstract>
<sec id="S1">
<title>Background</title>
<p id="P1">Lymphedema may disrupt local function and affect quality of life (QOL) in patients with head and neck cancer. The study aim was to examine the associations among severity of internal and external lymphedema, symptoms, functional status, and QOL in patients with head and neck cancer.</p>
</sec>
<sec id="S2">
<title>Methods</title>
<p id="P2">The sample included 103 patients who were ≥3 months post head and neck cancer treatment. Variables assessed included severity of internal and external lymphedema, physical/psychological symptoms, functional status, and QOL.</p>
</sec>
<sec id="S3">
<title>Results</title>
<p id="P3">Severity of internal and external lymphedema was associated with physical symptoms and psychological symptoms. Patients with more severe external lymphedema were more likely to have a decrease in neck left/right rotation. The combined effects of external and internal lymphedema severity were associated with hearing impairment and decreased QOL.</p>
</sec>
<sec id="S4">
<title>Conclusions</title>
<p id="P4">Lymphedema severity correlates with symptom burden, functional status, and QOL in patients post head and neck cancer treatment.</p>
</sec>
</abstract>
<kwd-group>
<kwd>Head and neck cancer</kwd>
<kwd>Lymphedema</kwd>
<kwd>Symptom</kwd>
<kwd>Functional Status</kwd>
<kwd>Quality of life (QOL)</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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