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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Near-infrared fluorescence imaging of lymphatics in head and neck lymphedema</title><author><name sortKey="Maus, Erik A" sort="Maus, Erik A" uniqKey="Maus E" first="Erik A." last="Maus">Erik A. Maus</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Tan, I Chih" sort="Tan, I Chih" uniqKey="Tan I" first="I-Chih" last="Tan">I-Chih Tan</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Rasmussen, John C" sort="Rasmussen, John C" uniqKey="Rasmussen J" first="John C." last="Rasmussen">John C. Rasmussen</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Marshall, Milton V" sort="Marshall, Milton V" uniqKey="Marshall M" first="Milton V." last="Marshall">Milton V. Marshall</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Fife, Caroline E" sort="Fife, Caroline E" uniqKey="Fife C" first="Caroline E." last="Fife">Caroline E. Fife</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Smith, Latisha A" sort="Smith, Latisha A" uniqKey="Smith L" first="Latisha A." last="Smith">Latisha A. Smith</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Guilliod, Renie" sort="Guilliod, Renie" uniqKey="Guilliod R" first="Renie" last="Guilliod">Renie Guilliod</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Sevick Muraca, Eva M" sort="Sevick Muraca, Eva M" uniqKey="Sevick Muraca E" first="Eva M." last="Sevick-Muraca">Eva M. Sevick-Muraca</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22311465</idno><idno type="pmc">3110984</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110984</idno><idno type="RBID">PMC:3110984</idno><idno type="doi">10.1002/hed.21538</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">003862</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003862</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Near-infrared fluorescence imaging of lymphatics in head and neck lymphedema</title><author><name sortKey="Maus, Erik A" sort="Maus, Erik A" uniqKey="Maus E" first="Erik A." last="Maus">Erik A. Maus</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Tan, I Chih" sort="Tan, I Chih" uniqKey="Tan I" first="I-Chih" last="Tan">I-Chih Tan</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Rasmussen, John C" sort="Rasmussen, John C" uniqKey="Rasmussen J" first="John C." last="Rasmussen">John C. Rasmussen</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Marshall, Milton V" sort="Marshall, Milton V" uniqKey="Marshall M" first="Milton V." last="Marshall">Milton V. Marshall</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Fife, Caroline E" sort="Fife, Caroline E" uniqKey="Fife C" first="Caroline E." last="Fife">Caroline E. Fife</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Smith, Latisha A" sort="Smith, Latisha A" uniqKey="Smith L" first="Latisha A." last="Smith">Latisha A. Smith</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Guilliod, Renie" sort="Guilliod, Renie" uniqKey="Guilliod R" first="Renie" last="Guilliod">Renie Guilliod</name><affiliation><nlm:aff id="A1"> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</nlm:aff></affiliation></author><author><name sortKey="Sevick Muraca, Eva M" sort="Sevick Muraca, Eva M" uniqKey="Sevick Muraca E" first="Eva M." last="Sevick-Muraca">Eva M. Sevick-Muraca</name><affiliation><nlm:aff id="A3"> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</nlm:aff></affiliation></author></analytic><series><title level="j">Head & neck</title><idno type="ISSN">1043-3074</idno><idno type="eISSN">1097-0347</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title><p id="P2">Lymphedema (LE) may be a complication following surgical resection and radiation treatment in a number of cancer types, and is especially debilitating in regions where treatment options are limited. While upper and lower extremity LE may be effectively treated with manual lymphatic drainage (MLD) therapies and devices that use compression to direct proximal flow of lymph, head and neck LE is more challenging.</p></sec><sec id="S2"><title>Methods and Results</title><p id="P3">Herein, we describe the compassionate use of an investigatory technique of near-infrared (NIR) fluorescence imaging to understand the lymphatic anatomy and function, help direct MLD, and use 3D surface profilometry to monitor response to therapy in a subject suffering head and neck LE following surgery and radiation treatment.</p></sec><sec id="S3"><title>Conclusion</title><p id="P4">NIR fluorescence imaging provides a mapping of functional lymph vessels for direction of efficient MLD therapy in the head and neck. Additional studies are needed to assess efficacy of MLD therapy when directed by NIR fluorescence imaging.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8902541</journal-id><journal-id journal-id-type="pubmed-jr-id">3967</journal-id><journal-id journal-id-type="nlm-ta">Head Neck</journal-id><journal-id journal-id-type="iso-abbrev">Head Neck</journal-id><journal-title-group><journal-title>Head & neck</journal-title></journal-title-group><issn pub-type="ppub">1043-3074</issn><issn pub-type="epub">1097-0347</issn></journal-meta><article-meta><article-id pub-id-type="pmid">22311465</article-id><article-id pub-id-type="pmc">3110984</article-id><article-id pub-id-type="doi">10.1002/hed.21538</article-id><article-id pub-id-type="manuscript">NIHMS216104</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Near-infrared fluorescence imaging of lymphatics in head and neck lymphedema</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Maus</surname><given-names>Erik A.</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="corresp" rid="CR2">5</xref><xref ref-type="author-notes" rid="FN1">*</xref></contrib><contrib contrib-type="author"><name><surname>Tan</surname><given-names>I-Chih</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A3">3</xref><xref ref-type="author-notes" rid="FN1">*</xref></contrib><contrib contrib-type="author"><name><surname>Rasmussen</surname><given-names>John C.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Marshall</surname><given-names>Milton V.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Fife</surname><given-names>Caroline E.</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Smith</surname><given-names>Latisha A.</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Guilliod</surname><given-names>Renie</given-names></name><degrees>M.D.</degrees><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Sevick-Muraca</surname><given-names>Eva M.</given-names></name><degrees>Ph.D.</degrees><xref ref-type="aff" rid="A3">3</xref><xref ref-type="corresp" rid="CR1">4</xref></contrib></contrib-group><aff id="A1"><label>1</label> Division of Cardiology and Hyperbaric Medicine, Department of Internal Medicine at The University of Texas Health Science Center, Houston, TX</aff><aff id="A2"><label>2</label> Memorial Hermann Center for Lymphedema Management, Memorial Hermann - Texas Medical Center, Houston, TX</aff><aff id="A3"><label>3</label> Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine at The University of Texas Health Science Center, Houston, TX</aff><author-notes><fn fn-type="equal" id="FN1"><label>*</label><p id="P1">These authors have equal contribution to this article</p></fn><corresp id="CR1"><label>4</label> To whom correspondence on technology and reprint request should be directed, 1825 Pressler St, SRB 330A, Houston, TX 77030, phone: 713-500-3560; fax: 713-500-0319; <email>eva.sevick@uth.tmc.edu</email></corresp><corresp id="CR2"><label>5</label> To whom correspondence on clinical aspects should be directed, 6411 Fannin St, 2<sup>nd</sup> Floor Robertson Bldg, Houston, TX 77030, phone: 713-704-1246; fax: 713-704-5793; <email>erik.a.maus@uth.tmc.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>29</day><month>6</month><year>2010</year></pub-date><pub-date pub-type="epub"><day>12</day><month>11</month><year>2010</year></pub-date><pub-date pub-type="ppub"><month>3</month><year>2012</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>3</month><year>2013</year></pub-date><volume>34</volume><issue>3</issue><fpage>448</fpage><lpage>453</lpage><abstract><sec id="S1"><title>Background</title><p id="P2">Lymphedema (LE) may be a complication following surgical resection and radiation treatment in a number of cancer types, and is especially debilitating in regions where treatment options are limited. While upper and lower extremity LE may be effectively treated with manual lymphatic drainage (MLD) therapies and devices that use compression to direct proximal flow of lymph, head and neck LE is more challenging.</p></sec><sec id="S2"><title>Methods and Results</title><p id="P3">Herein, we describe the compassionate use of an investigatory technique of near-infrared (NIR) fluorescence imaging to understand the lymphatic anatomy and function, help direct MLD, and use 3D surface profilometry to monitor response to therapy in a subject suffering head and neck LE following surgery and radiation treatment.</p></sec><sec id="S3"><title>Conclusion</title><p id="P4">NIR fluorescence imaging provides a mapping of functional lymph vessels for direction of efficient MLD therapy in the head and neck. Additional studies are needed to assess efficacy of MLD therapy when directed by NIR fluorescence imaging.</p></sec></abstract><kwd-group><kwd>fluorescence imaging</kwd><kwd>lymphedema</kwd><kwd>manual lymph drainage</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Cancer Institute : NCI</funding-source><award-id>U54 CA136404-01 || CA</award-id></award-group><award-group><funding-source country="United States">National Heart, Lung, and Blood Institute : NHLBI</funding-source><award-id>R01 HL092923-01 || HL</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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