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Bacillus Calmette-Guérin (BCG) complications associated with primary immunodeficiency diseases

Identifieur interne : 003729 ( Pmc/Corpus ); précédent : 003728; suivant : 003730

Bacillus Calmette-Guérin (BCG) complications associated with primary immunodeficiency diseases

Auteurs : Sayna Norouzi ; Asghar Aghamohammadi ; Setareh Mamishi ; Sergio D. Rosenzweig ; Nima Rezaei

Source :

RBID : PMC:4792288

Abstract

Summary

Primary immunodeficiency diseases (PIDs) are a group of inherited disorders, characterized by defects of the immune system predisposing individuals to variety of manifestations, including recurrent infections and unusual vaccine complications. There are a number of PIDs prone to Bacillus Calmette-Guérin (BCG) complications. This review presents an update on our understanding about the BCGosis-susceptible PIDs, including severe combined immunodeficiency, chronic granulomatous disease, and Mendelian susceptibility to mycobacterial diseases.


Url:
DOI: 10.1016/j.jinf.2012.03.012
PubMed: 22430715
PubMed Central: 4792288

Links to Exploration step

PMC:4792288

Le document en format XML

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<p id="P1">Primary immunodeficiency diseases (PIDs) are a group of inherited disorders, characterized by defects of the immune system predisposing individuals to variety of manifestations, including recurrent infections and unusual vaccine complications. There are a number of PIDs prone to Bacillus Calmette-Guérin (BCG) complications. This review presents an update on our understanding about the BCGosis-susceptible PIDs, including severe combined immunodeficiency, chronic granulomatous disease, and Mendelian susceptibility to mycobacterial diseases.</p>
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Pediatric Infectious Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran</aff>
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Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran</aff>
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Infectious Diseases Susceptibility Unit, Laboratory of Host Defenses, Primary Immunodeficiency Clinic, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA</aff>
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Molecular Immunology Research Center, Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</aff>
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Department of Infection and Immunity, School of Medicine and Biomedical Sciences, The University of Sheffield, Sheffield, UK</aff>
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Corresponding author. Research Center for Immunodeficiencies, Children’s Medical Center Hospital, Dr Qarib St, Keshavarz Blvd, Tehran 14194, Iran. Tel.: +9821 6692 9234; fax: 9821 6692 9235.
<email>rezaei_nima@yahoo.com</email>
,
<email>rezaei_nima@tums.ac.i</email>
(N. Rezaei)</corresp>
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<title>Summary</title>
<p id="P1">Primary immunodeficiency diseases (PIDs) are a group of inherited disorders, characterized by defects of the immune system predisposing individuals to variety of manifestations, including recurrent infections and unusual vaccine complications. There are a number of PIDs prone to Bacillus Calmette-Guérin (BCG) complications. This review presents an update on our understanding about the BCGosis-susceptible PIDs, including severe combined immunodeficiency, chronic granulomatous disease, and Mendelian susceptibility to mycobacterial diseases.</p>
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