LymphedemaV1, Pmc, Corpus, bibRecord, 003635

Warts and All: HPV in Primary Immunodeficiencies

Identifieur interne : 003635 ( Pmc/Corpus ); précédent : 003634; suivant : 003636

Warts and All: HPV in Primary Immunodeficiencies

Auteurs : Jennifer W. Leiding ; Steven M. Holland

Source :

The Journal of allergy and clinical immunology [ 0091-6749 ] ; 2012.

RBID : PMC:3517887

Abstract

Infection with human papilloma virus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in EVER1, EVER2, GATA2, CXCR4, and DOCK8 are typically associated with extensive HPV infections, whereas several other primary immune defects have severe HPV much less frequently. We review immunodeficiencies with severe HPV infections and the mechanisms underlying them.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517887

DOI: 10.1016/j.jaci.2012.07.049
PubMed: 23036745
PubMed Central: 3517887

Links to Exploration step

PMC:3517887

Le document en format XML

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<author><name sortKey="Leiding, Jennifer W" sort="Leiding, Jennifer W" uniqKey="Leiding J" first="Jennifer W." last="Leiding">Jennifer W. Leiding</name>
<affiliation><nlm:aff id="A1">Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Holland, Steven M" sort="Holland, Steven M" uniqKey="Holland S" first="Steven M." last="Holland">Steven M. Holland</name>
<affiliation><nlm:aff id="A1">Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md USA</nlm:aff>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Warts and All: HPV in Primary Immunodeficiencies</title>
<author><name sortKey="Leiding, Jennifer W" sort="Leiding, Jennifer W" uniqKey="Leiding J" first="Jennifer W." last="Leiding">Jennifer W. Leiding</name>
<affiliation><nlm:aff id="A1">Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md USA</nlm:aff>
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<author><name sortKey="Holland, Steven M" sort="Holland, Steven M" uniqKey="Holland S" first="Steven M." last="Holland">Steven M. Holland</name>
<affiliation><nlm:aff id="A1">Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md USA</nlm:aff>
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<series><title level="j">The Journal of allergy and clinical immunology</title>
<idno type="ISSN">0091-6749</idno>
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<front><div type="abstract" xml:lang="en"><p id="P1">Infection with human papilloma virus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in <italic>EVER1, EVER2, GATA2, CXCR4</italic>
, and <italic>DOCK8</italic>
 are typically associated with extensive HPV infections, whereas several other primary immune defects have severe HPV much less frequently. We review immunodeficiencies with severe HPV infections and the mechanisms underlying them.</p>
</div>
</front>
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<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <pmc-dir>properties manuscript</pmc-dir>
  <front><journal-meta><journal-id journal-id-type="nlm-journal-id">1275002</journal-id>
<journal-id journal-id-type="pubmed-jr-id">4431</journal-id>
<journal-id journal-id-type="nlm-ta">J Allergy Clin Immunol</journal-id>
<journal-id journal-id-type="iso-abbrev">J. Allergy Clin. Immunol.</journal-id>
<journal-title-group><journal-title>The Journal of allergy and clinical immunology</journal-title>
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<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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<title-group><article-title>Warts and All: HPV in Primary Immunodeficiencies</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Leiding</surname>
<given-names>Jennifer W.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A1">1</xref>
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<contrib contrib-type="author"><name><surname>Holland</surname>
<given-names>Steven M.</given-names>
</name>
<degrees>MD</degrees>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
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<aff id="A1"><label>1</label>
Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md USA</aff>
<author-notes><corresp id="FN1">Corresponding Author Jennifer W. Leiding, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive, CRC, Rm B3-4233, MSC 1684, Bethesda, Md 20892-1684, Tel: 301-496-5102, Fax: 301-480-4507, <email>leidingjw@niaid.nih.gov</email>
</corresp>
<corresp id="FN2">Alternate Corresponding Author Steven M. Holland, MD, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Drive, CRC, Rm B3-4233, MSC 1684, Bethesda, Md 20892-1684, Tel: 301-402-7684, Fax: 301-480-4507, <email>smh@nih.gov</email>
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<pub-date pub-type="nihms-submitted"><day>2</day>
<month>11</month>
<year>2012</year>
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<pub-date pub-type="epub"><day>01</day>
<month>10</month>
<year>2012</year>
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<pub-date pub-type="ppub"><month>11</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>11</month>
<year>2013</year>
</pub-date>
<volume>130</volume>
<issue>5</issue>
<fpage>1030</fpage>
<lpage>1048</lpage>
<abstract><p id="P1">Infection with human papilloma virus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in <italic>EVER1, EVER2, GATA2, CXCR4</italic>
, and <italic>DOCK8</italic>
 are typically associated with extensive HPV infections, whereas several other primary immune defects have severe HPV much less frequently. We review immunodeficiencies with severe HPV infections and the mechanisms underlying them.</p>
</abstract>
<kwd-group><kwd>Immunodeficiency</kwd>
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<kwd>warts</kwd>
<kwd>squamous</kwd>
<kwd>carcinoma</kwd>
<kwd>dysplastic</kwd>
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<funding-group><award-group><funding-source country="United States">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</funding-source>
<award-id>Z99 AI999999 || AI</award-id>
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Warts and All: HPV in Primary Immunodeficiencies

Warts and All: HPV in Primary Immunodeficiencies

Source :

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki