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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Engineering the Lymphatic System</title><author><name sortKey="Nipper, Matthew E" sort="Nipper, Matthew E" uniqKey="Nipper M" first="Matthew E." last="Nipper">Matthew E. Nipper</name></author><author><name sortKey="Dixon, J Brandon" sort="Dixon, J Brandon" uniqKey="Dixon J" first="J. Brandon" last="Dixon">J. Brandon Dixon</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23408477</idno><idno type="pmc">3568779</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568779</idno><idno type="RBID">PMC:3568779</idno><idno type="doi">10.1007/s13239-011-0054-6</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">003595</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003595</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Engineering the Lymphatic System</title><author><name sortKey="Nipper, Matthew E" sort="Nipper, Matthew E" uniqKey="Nipper M" first="Matthew E." last="Nipper">Matthew E. Nipper</name></author><author><name sortKey="Dixon, J Brandon" sort="Dixon, J Brandon" uniqKey="Dixon J" first="J. Brandon" last="Dixon">J. Brandon Dixon</name></author></analytic><series><title level="j">Cardiovascular engineering and technology</title><idno type="ISSN">1869-408X</idno><idno type="eISSN">1869-4098</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The recent advances in our understanding of lymphatic physiology and the role of the lymphatics in actively regulating fluid balance, lipid transport, and immune cell trafficking has been furthered in part through innovations in imaging, tissue engineering, quantitative biology, biomechanics, and computational modeling. Interdisciplinary and bioengineering approaches will continue to be crucial to the progression of the field, given that lymphatic biology and function are intimately woven with the local microenvironment and mechanical loads experienced by the vessel. This is particularly the case in lymphatic diseases such as lymphedema where the microenvironment can be drastically altered by tissue fibrosis and adipocyte accumulation. In this review we will highlight contributions engineering and mechanics have made to lymphatic physiology and will discuss areas that will be important for future research.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101531846</journal-id><journal-id journal-id-type="pubmed-jr-id">37661</journal-id><journal-id journal-id-type="nlm-ta">Cardiovasc Eng Technol</journal-id><journal-id journal-id-type="iso-abbrev">Cardiovasc Eng Technol</journal-id><journal-title-group><journal-title>Cardiovascular engineering and technology</journal-title></journal-title-group><issn pub-type="ppub">1869-408X</issn><issn pub-type="epub">1869-4098</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23408477</article-id><article-id pub-id-type="pmc">3568779</article-id><article-id pub-id-type="doi">10.1007/s13239-011-0054-6</article-id><article-id pub-id-type="manuscript">NIHMS328505</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Engineering the Lymphatic System</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Nipper</surname><given-names>Matthew E.</given-names></name></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Dixon</surname><given-names>J. Brandon</given-names></name><email>dixon@gatech.edu</email></contrib><aff id="A1">Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Tel.: +404-385-3915, Fax: +404-385-1397</aff></contrib-group><pub-date pub-type="nihms-submitted"><day>11</day><month>10</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>7</month><year>2011</year></pub-date><pub-date pub-type="ppub"><month>12</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>11</day><month>2</month><year>2013</year></pub-date><volume>2</volume><issue>4</issue><fpage>296</fpage><lpage>308</lpage><self-uri xlink:href="http://link.springer.com/article/10.1007/s13239-011-0054-6/fulltext.html"></self-uri><abstract><p id="P1">The recent advances in our understanding of lymphatic physiology and the role of the lymphatics in actively regulating fluid balance, lipid transport, and immune cell trafficking has been furthered in part through innovations in imaging, tissue engineering, quantitative biology, biomechanics, and computational modeling. Interdisciplinary and bioengineering approaches will continue to be crucial to the progression of the field, given that lymphatic biology and function are intimately woven with the local microenvironment and mechanical loads experienced by the vessel. This is particularly the case in lymphatic diseases such as lymphedema where the microenvironment can be drastically altered by tissue fibrosis and adipocyte accumulation. In this review we will highlight contributions engineering and mechanics have made to lymphatic physiology and will discuss areas that will be important for future research.</p></abstract><kwd-group><kwd>lymphatic</kwd><kwd>biomechanics</kwd><kwd>lymphedema</kwd><kwd>imaging</kwd><kwd>shear stress</kwd><kwd>tissue engineering</kwd></kwd-group><funding-group><award-group><funding-source country="United States">National Heart, Lung, and Blood Institute : NHLBI</funding-source><award-id>R00 HL091133-04 || HL</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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