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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Brief Account of Nanoparticle Contrast Agents for Photoacoustic Imaging</title><author><name sortKey="Pan, Dipanjan" sort="Pan, Dipanjan" uniqKey="Pan D" first="Dipanjan" last="Pan">Dipanjan Pan</name><affiliation><nlm:aff id="A1">Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</nlm:aff></affiliation></author><author><name sortKey="Kim, Benjamin" sort="Kim, Benjamin" uniqKey="Kim B" first="Benjamin" last="Kim">Benjamin Kim</name><affiliation><nlm:aff id="A1">Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</nlm:aff></affiliation></author><author><name sortKey="Wang, Lihong V" sort="Wang, Lihong V" uniqKey="Wang L" first="Lihong V." last="Wang">Lihong V. Wang</name><affiliation><nlm:aff id="A2">Department of Biomedical Engineering, Washington University, St Louis, MO 63130</nlm:aff></affiliation></author><author><name sortKey="Lanza, Gregory M" sort="Lanza, Gregory M" uniqKey="Lanza G" first="Gregory M" last="Lanza">Gregory M. Lanza</name><affiliation><nlm:aff id="A1">Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23983210</idno><idno type="pmc">4067981</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067981</idno><idno type="RBID">PMC:4067981</idno><idno type="doi">10.1002/wnan.1231</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">003580</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003580</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Brief Account of Nanoparticle Contrast Agents for Photoacoustic Imaging</title><author><name sortKey="Pan, Dipanjan" sort="Pan, Dipanjan" uniqKey="Pan D" first="Dipanjan" last="Pan">Dipanjan Pan</name><affiliation><nlm:aff id="A1">Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</nlm:aff></affiliation></author><author><name sortKey="Kim, Benjamin" sort="Kim, Benjamin" uniqKey="Kim B" first="Benjamin" last="Kim">Benjamin Kim</name><affiliation><nlm:aff id="A1">Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</nlm:aff></affiliation></author><author><name sortKey="Wang, Lihong V" sort="Wang, Lihong V" uniqKey="Wang L" first="Lihong V." last="Wang">Lihong V. Wang</name><affiliation><nlm:aff id="A2">Department of Biomedical Engineering, Washington University, St Louis, MO 63130</nlm:aff></affiliation></author><author><name sortKey="Lanza, Gregory M" sort="Lanza, Gregory M" uniqKey="Lanza G" first="Gregory M" last="Lanza">Gregory M. Lanza</name><affiliation><nlm:aff id="A1">Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</nlm:aff></affiliation></author></analytic><series><title level="j">Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology</title><idno type="ISSN">1939-5116</idno><idno type="eISSN">1939-0041</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Photoacoustic imaging (PAI) is a hybrid, nonionizing modality offering excellent spatial resolution, deep penetration, and high soft tissue contrast. In PAI, signal is generated based on the absorption of laser-generated optical energy by endogenous tissues or exogenous contrast agents leading to acoustic emissions detected by an ultrasound transducer. Research in this area over the years has shown that PAI has the ability to provide both physiological and molecular imaging, which can be viewed alone or used in a hybrid modality fashion to extend the anatomic and hemodynamic sensitivities of clinical ultrasound. PAI may be performed using inherent contrast afforded by light absorbing molecules such as hemoglobin, myoglobin, and melanin or exogenous small molecule contrast agent such as near infrared dyes and porphyrins. However, this review summarizes the potential of exogenous nanoparticle-based agents for PAI applications including contrast based on gold particles, carbon nanotubes, and encapsulated copper compounds.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101508311</journal-id><journal-id journal-id-type="pubmed-jr-id">36716</journal-id><journal-id journal-id-type="nlm-ta">Wiley Interdiscip Rev Nanomed Nanobiotechnol</journal-id><journal-id journal-id-type="iso-abbrev">Wiley Interdiscip Rev Nanomed Nanobiotechnol</journal-id><journal-title-group><journal-title>Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology</journal-title></journal-title-group><issn pub-type="ppub">1939-5116</issn><issn pub-type="epub">1939-0041</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23983210</article-id><article-id pub-id-type="pmc">4067981</article-id><article-id pub-id-type="doi">10.1002/wnan.1231</article-id><article-id pub-id-type="manuscript">NIHMS489519</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>A Brief Account of Nanoparticle Contrast Agents for Photoacoustic Imaging</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Pan</surname><given-names>Dipanjan</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Kim</surname><given-names>Benjamin</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Lihong V.</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Lanza</surname><given-names>Gregory M</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Medicine, Washington University School of Medicine, St Louis, MO 63108</aff><aff id="A2"><label>2</label>Department of Biomedical Engineering, Washington University, St Louis, MO 63130</aff><author-notes><corresp id="cor1">Address correspondence to: Dipanjan Pan, PhD, Assistant Professor in Medicine, Research, Division of Cardiology, Campus Box 8215, 660 Euclid Ave, Washington University School of Medicine, St. Louis, MO 63108, Tel: 314-454-7674, Fax: 314-454-5265, <email>dpan@dom.wustl.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>23</day><month>5</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>23</day><month>8</month><year>2013</year></pub-date><pub-date pub-type="ppub"><season>Nov-Dec</season><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>11</month><year>2014</year></pub-date><volume>5</volume><issue>6</issue><fpage>517</fpage><lpage>543</lpage><pmc-comment>elocation-id from pubmed: 10.1002/wnan.1231</pmc-comment>
<abstract><p id="P1">Photoacoustic imaging (PAI) is a hybrid, nonionizing modality offering excellent spatial resolution, deep penetration, and high soft tissue contrast. In PAI, signal is generated based on the absorption of laser-generated optical energy by endogenous tissues or exogenous contrast agents leading to acoustic emissions detected by an ultrasound transducer. Research in this area over the years has shown that PAI has the ability to provide both physiological and molecular imaging, which can be viewed alone or used in a hybrid modality fashion to extend the anatomic and hemodynamic sensitivities of clinical ultrasound. PAI may be performed using inherent contrast afforded by light absorbing molecules such as hemoglobin, myoglobin, and melanin or exogenous small molecule contrast agent such as near infrared dyes and porphyrins. However, this review summarizes the potential of exogenous nanoparticle-based agents for PAI applications including contrast based on gold particles, carbon nanotubes, and encapsulated copper compounds.</p></abstract><kwd-group><kwd>Photoacoustic imaging</kwd><kwd>gold nanoparticle</kwd><kwd>copper nanoparticle</kwd><kwd>carbon nanoparticle</kwd><kwd>NIR dyes</kwd><kwd>porphyrins</kwd><kwd>fibrin</kwd><kwd>angiogenesis</kwd><kwd>melanoma</kwd><kwd>sentinel lymphnode</kwd><kwd>thrombus</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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