Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Risk Factors Associated with Breast Cancer-Related Lymphedema in the WHEL Study</title>
<author><name sortKey="Dominick, Sally A" sort="Dominick, Sally A" uniqKey="Dominick S" first="Sally A." last="Dominick">Sally A. Dominick</name>
</author>
<author><name sortKey="Madlensky, Lisa" sort="Madlensky, Lisa" uniqKey="Madlensky L" first="Lisa" last="Madlensky">Lisa Madlensky</name>
</author>
<author><name sortKey="Natarajan, Loki" sort="Natarajan, Loki" uniqKey="Natarajan L" first="Loki" last="Natarajan">Loki Natarajan</name>
</author>
<author><name sortKey="Pierce, John P" sort="Pierce, John P" uniqKey="Pierce J" first="John P." last="Pierce">John P. Pierce</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">23212606</idno>
<idno type="pmc">3568206</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568206</idno>
<idno type="RBID">PMC:3568206</idno>
<idno type="doi">10.1007/s11764-012-0251-9</idno>
<date when="2012">2012</date>
<idno type="wicri:Area/Pmc/Corpus">003540</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003540</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Risk Factors Associated with Breast Cancer-Related Lymphedema in the WHEL Study</title>
<author><name sortKey="Dominick, Sally A" sort="Dominick, Sally A" uniqKey="Dominick S" first="Sally A." last="Dominick">Sally A. Dominick</name>
</author>
<author><name sortKey="Madlensky, Lisa" sort="Madlensky, Lisa" uniqKey="Madlensky L" first="Lisa" last="Madlensky">Lisa Madlensky</name>
</author>
<author><name sortKey="Natarajan, Loki" sort="Natarajan, Loki" uniqKey="Natarajan L" first="Loki" last="Natarajan">Loki Natarajan</name>
</author>
<author><name sortKey="Pierce, John P" sort="Pierce, John P" uniqKey="Pierce J" first="John P." last="Pierce">John P. Pierce</name>
</author>
</analytic>
<series><title level="j">Journal of cancer survivorship : research and practice</title>
<idno type="ISSN">1932-2259</idno>
<idno type="eISSN">1932-2267</idno>
<imprint><date when="2012">2012</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Introduction</title>
<p id="P1">Lymphedema is a significant health problem faced by a large percentage of breast cancer survivors. The Women’s Healthy Eating and Living (WHEL) Study has a unique data set collected after the completion of breast cancer treatment, which allowed a focused analysis of risk factors for breast cancer-related lymphedema.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Participant characteristics, treatment modalities, and health behaviors were examined as potential predictors of lymphedema among breast cancer survivors with univariate analyses and multivariate logistic regression.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Lymphedema status was assessed for 83% of the study cohort (2431 of the 2917 WHEL participants). Among these respondents, 692 (28.5%) women reported yes to either a physician’s diagnosis of lymphedema or a question on arm/hand swelling. When compared to other participants, women with lymphedema were diagnosed at a younger age, more likely to have a higher body mass index, had a larger tumor size, had more lymph nodes removed, more likely to have a mastectomy with radiation therapy, and more likely to have chemotherapy. In the final multivariate-adjusted model, body mass index greater than 25 kg/m<sup>2</sup>
(p<0.01), the removal of 11 or more lymph nodes (p<0.01), and breast cancer surgery plus radiation therapy (p<0.01) showed a strong independent association with developing breast cancer-related lymphedema.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">The results of this study highlight the importance of educating breast cancer survivors about the modifiable risk factors (e.g., body mass index) associated with the development of lymphedema.</p>
</sec>
<sec id="S5"><title>Implications for Cancer Survivors</title>
<p id="P5">Breast cancer survivors at risk for lymphedema may benefit from interventions aimed at achieving or maintaining a healthy body weight.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101307557</journal-id>
<journal-id journal-id-type="pubmed-jr-id">34604</journal-id>
<journal-id journal-id-type="nlm-ta">J Cancer Surviv</journal-id>
<journal-id journal-id-type="iso-abbrev">J Cancer Surviv</journal-id>
<journal-title-group><journal-title>Journal of cancer survivorship : research and practice</journal-title>
</journal-title-group>
<issn pub-type="ppub">1932-2259</issn>
<issn pub-type="epub">1932-2267</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">23212606</article-id>
<article-id pub-id-type="pmc">3568206</article-id>
<article-id pub-id-type="doi">10.1007/s11764-012-0251-9</article-id>
<article-id pub-id-type="manuscript">NIHMS426734</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Risk Factors Associated with Breast Cancer-Related Lymphedema in the WHEL Study</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Dominick</surname>
<given-names>Sally A.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Madlensky</surname>
<given-names>Lisa</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Natarajan</surname>
<given-names>Loki</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Pierce</surname>
<given-names>John P.</given-names>
</name>
</contrib>
<aff id="A1">Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA</aff>
</contrib-group>
<author-notes><corresp id="cor1"><bold>Corresponding Author:</bold>
John P. Pierce, Ph.D., Cancer Prevention and Control Program, Moores UCSD Cancer Center, University of California, San Diego, 3855 Health Sciences Drive, La Jolla, CA 92093-0901; Telephone: 858-822-2380; Fax: 858-822-2399; <email>jppierce@ucsd.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>10</day>
<month>12</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="epub"><day>05</day>
<month>12</month>
<year>2012</year>
</pub-date>
<pub-date pub-type="ppub"><month>3</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>01</day>
<month>3</month>
<year>2014</year>
</pub-date>
<volume>7</volume>
<issue>1</issue>
<fpage>115</fpage>
<lpage>123</lpage>
<abstract><sec id="S1"><title>Introduction</title>
<p id="P1">Lymphedema is a significant health problem faced by a large percentage of breast cancer survivors. The Women’s Healthy Eating and Living (WHEL) Study has a unique data set collected after the completion of breast cancer treatment, which allowed a focused analysis of risk factors for breast cancer-related lymphedema.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">Participant characteristics, treatment modalities, and health behaviors were examined as potential predictors of lymphedema among breast cancer survivors with univariate analyses and multivariate logistic regression.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Lymphedema status was assessed for 83% of the study cohort (2431 of the 2917 WHEL participants). Among these respondents, 692 (28.5%) women reported yes to either a physician’s diagnosis of lymphedema or a question on arm/hand swelling. When compared to other participants, women with lymphedema were diagnosed at a younger age, more likely to have a higher body mass index, had a larger tumor size, had more lymph nodes removed, more likely to have a mastectomy with radiation therapy, and more likely to have chemotherapy. In the final multivariate-adjusted model, body mass index greater than 25 kg/m<sup>2</sup>
(p<0.01), the removal of 11 or more lymph nodes (p<0.01), and breast cancer surgery plus radiation therapy (p<0.01) showed a strong independent association with developing breast cancer-related lymphedema.</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">The results of this study highlight the importance of educating breast cancer survivors about the modifiable risk factors (e.g., body mass index) associated with the development of lymphedema.</p>
</sec>
<sec id="S5"><title>Implications for Cancer Survivors</title>
<p id="P5">Breast cancer survivors at risk for lymphedema may benefit from interventions aimed at achieving or maintaining a healthy body weight.</p>
</sec>
</abstract>
<kwd-group><kwd>Breast cancer survivors</kwd>
<kwd>Lymphedema</kwd>
<kwd>Risk factors</kwd>
<kwd>Body mass index</kwd>
<kwd>Lymph node removal</kwd>
<kwd>Breast cancer treatment</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003540 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 003540 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= LymphedemaV1 |flux= Pmc |étape= Corpus |type= RBID |clé= |texte= }}
This area was generated with Dilib version V0.6.31. |