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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Handheld Reflectance Confocal Microscopy to Aid in the Management of Complex Facial Lentigo Maligna</title>
<author><name sortKey="Hibler, Brian P" sort="Hibler, Brian P" uniqKey="Hibler B" first="Brian P." last="Hibler">Brian P. Hibler</name>
</author>
<author><name sortKey="Yelamos, Oriol" sort="Yelamos, Oriol" uniqKey="Yelamos O" first="Oriol" last="Yélamos">Oriol Yélamos</name>
</author>
<author><name sortKey="Cordova, Miguel" sort="Cordova, Miguel" uniqKey="Cordova M" first="Miguel" last="Cordova">Miguel Cordova</name>
</author>
<author><name sortKey="Sierra, Heidy" sort="Sierra, Heidy" uniqKey="Sierra H" first="Heidy" last="Sierra">Heidy Sierra</name>
</author>
<author><name sortKey="Rajadhyaksha, Milind" sort="Rajadhyaksha, Milind" uniqKey="Rajadhyaksha M" first="Milind" last="Rajadhyaksha">Milind Rajadhyaksha</name>
</author>
<author><name sortKey="Nehal, Kishwer S" sort="Nehal, Kishwer S" uniqKey="Nehal K" first="Kishwer S." last="Nehal">Kishwer S. Nehal</name>
</author>
<author><name sortKey="Rossi, Anthony M" sort="Rossi, Anthony M" uniqKey="Rossi A" first="Anthony M." last="Rossi">Anthony M. Rossi</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">28632796</idno>
<idno type="pmc">5569302</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569302</idno>
<idno type="RBID">PMC:5569302</idno>
<date when="2017">2017</date>
<idno type="wicri:Area/Pmc/Corpus">003229</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">003229</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Handheld Reflectance Confocal Microscopy to Aid in the Management of Complex Facial Lentigo Maligna</title>
<author><name sortKey="Hibler, Brian P" sort="Hibler, Brian P" uniqKey="Hibler B" first="Brian P." last="Hibler">Brian P. Hibler</name>
</author>
<author><name sortKey="Yelamos, Oriol" sort="Yelamos, Oriol" uniqKey="Yelamos O" first="Oriol" last="Yélamos">Oriol Yélamos</name>
</author>
<author><name sortKey="Cordova, Miguel" sort="Cordova, Miguel" uniqKey="Cordova M" first="Miguel" last="Cordova">Miguel Cordova</name>
</author>
<author><name sortKey="Sierra, Heidy" sort="Sierra, Heidy" uniqKey="Sierra H" first="Heidy" last="Sierra">Heidy Sierra</name>
</author>
<author><name sortKey="Rajadhyaksha, Milind" sort="Rajadhyaksha, Milind" uniqKey="Rajadhyaksha M" first="Milind" last="Rajadhyaksha">Milind Rajadhyaksha</name>
</author>
<author><name sortKey="Nehal, Kishwer S" sort="Nehal, Kishwer S" uniqKey="Nehal K" first="Kishwer S." last="Nehal">Kishwer S. Nehal</name>
</author>
<author><name sortKey="Rossi, Anthony M" sort="Rossi, Anthony M" uniqKey="Rossi A" first="Anthony M." last="Rossi">Anthony M. Rossi</name>
</author>
</analytic>
<series><title level="j">Cutis</title>
<idno type="ISSN">0011-4162</idno>
<idno type="eISSN">2326-6929</idno>
<imprint><date when="2017">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Diagnosis and management of lentigo maligna (LM) and LM melanoma (LMM) is challenging. Novel noninvasive imaging technologies such as reflectance confocal microscopy (RCM) have advanced the ability to better diagnose and monitor challenging lesions. In addition, the new handheld RCM (HRCM) together with the use of videomosaics has allowed an accurate evaluation of large lesions in concave/convex areas of the body (eg, the face). Herein, we review the impact of HRCM in the detection, treatment decision-making, and monitoring of 5 cases of complex facial LM/LMM. In the cases presented, HRCM enabled the detection of subclinical margins, presence of invasion, detection of persistence/recurrence, and monitoring of surgical and nonsurgical therapies. In this preliminary report, our results suggest that HRCM is a versatile ancillary tool in pretreatment decision-making, intraoperative surgical mapping, and posttreatment monitoring of complex facial LM/LMM.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">0006440</journal-id>
<journal-id journal-id-type="pubmed-jr-id">3245</journal-id>
<journal-id journal-id-type="nlm-ta">Cutis</journal-id>
<journal-id journal-id-type="iso-abbrev">Cutis</journal-id>
<journal-title-group><journal-title>Cutis</journal-title>
</journal-title-group>
<issn pub-type="ppub">0011-4162</issn>
<issn pub-type="epub">2326-6929</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">28632796</article-id>
<article-id pub-id-type="pmc">5569302</article-id>
<article-id pub-id-type="manuscript">NIHMS889179</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Handheld Reflectance Confocal Microscopy to Aid in the Management of Complex Facial Lentigo Maligna</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Hibler</surname>
<given-names>Brian P.</given-names>
</name>
<degrees>MD</degrees>
<aff id="A1">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Yélamos</surname>
<given-names>Oriol</given-names>
</name>
<degrees>MD</degrees>
<aff id="A2">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
<aff id="A3">Dr. Yélamos also is from the Dermatology Department, Hospital Clínic, Universitat de Barcelona, Spain</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Cordova</surname>
<given-names>Miguel</given-names>
</name>
<degrees>MD</degrees>
<aff id="A4">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Sierra</surname>
<given-names>Heidy</given-names>
</name>
<degrees>PhD</degrees>
<aff id="A5">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Rajadhyaksha</surname>
<given-names>Milind</given-names>
</name>
<degrees>PhD</degrees>
<aff id="A6">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Nehal</surname>
<given-names>Kishwer S.</given-names>
</name>
<degrees>MD</degrees>
<aff id="A7">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Rossi</surname>
<given-names>Anthony M.</given-names>
</name>
<degrees>MD</degrees>
<aff id="A8">Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York</aff>
<aff id="A9">Dr. Rossi also is from the Department of Dermatology, Weill Cornell Medical College, New York</aff>
</contrib>
</contrib-group>
<author-notes><corresp id="FN1">Correspondence: Anthony M. Rossi, MD, Memorial Sloan Kettering Cancer Center, Dermatology Service, 16 E 60th St, Ste 407, New York, NY 10022 (<email>rossia@mskcc.org</email>
)</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>1</day>
<month>7</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="ppub"><month>5</month>
<year>2017</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>24</day>
<month>8</month>
<year>2017</year>
</pub-date>
<volume>99</volume>
<issue>5</issue>
<fpage>346</fpage>
<lpage>352</lpage>
<abstract><p id="P1">Diagnosis and management of lentigo maligna (LM) and LM melanoma (LMM) is challenging. Novel noninvasive imaging technologies such as reflectance confocal microscopy (RCM) have advanced the ability to better diagnose and monitor challenging lesions. In addition, the new handheld RCM (HRCM) together with the use of videomosaics has allowed an accurate evaluation of large lesions in concave/convex areas of the body (eg, the face). Herein, we review the impact of HRCM in the detection, treatment decision-making, and monitoring of 5 cases of complex facial LM/LMM. In the cases presented, HRCM enabled the detection of subclinical margins, presence of invasion, detection of persistence/recurrence, and monitoring of surgical and nonsurgical therapies. In this preliminary report, our results suggest that HRCM is a versatile ancillary tool in pretreatment decision-making, intraoperative surgical mapping, and posttreatment monitoring of complex facial LM/LMM.</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>
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