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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Absence of lymphatic vessels in the dog dental pulp: an immunohistochemical study</title><author><name sortKey="Martin, Anna" sort="Martin, Anna" uniqKey="Martin A" first="Anna" last="Martin">Anna Martin</name></author><author><name sortKey="Gasse, Hagen" sort="Gasse, Hagen" uniqKey="Gasse H" first="Hagen" last="Gasse">Hagen Gasse</name></author><author><name sortKey="Staszyk, Carsten" sort="Staszyk, Carsten" uniqKey="Staszyk C" first="Carsten" last="Staszyk">Carsten Staszyk</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20854283</idno><idno type="pmc">3035865</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035865</idno><idno type="RBID">PMC:3035865</idno><idno type="doi">10.1111/j.1469-7580.2010.01298.x</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">002E83</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E83</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Absence of lymphatic vessels in the dog dental pulp: an immunohistochemical study</title><author><name sortKey="Martin, Anna" sort="Martin, Anna" uniqKey="Martin A" first="Anna" last="Martin">Anna Martin</name></author><author><name sortKey="Gasse, Hagen" sort="Gasse, Hagen" uniqKey="Gasse H" first="Hagen" last="Gasse">Hagen Gasse</name></author><author><name sortKey="Staszyk, Carsten" sort="Staszyk, Carsten" uniqKey="Staszyk C" first="Carsten" last="Staszyk">Carsten Staszyk</name></author></analytic><series><title level="j">Journal of Anatomy</title><idno type="ISSN">0021-8782</idno><idno type="eISSN">1469-7580</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In spite of numerous investigations it has not been precisely determined whether lymphatic vessels are present in the dental pulp of dogs. Therefore, this study attempted a specific immunohistochemical detection of lymphatic endothelium. The canine teeth of 19 healthy beagle dogs were dissected into three segments (apical, intermediate and occlusal). After decalcification, specimens were embedded in paraffin wax and histologic cross-sections were stained immunohistochemically using a reliable antibody (anti-Prox-1) against the homeobox transcription factor Prox-1, which is located within the nucleus of lymphatic endothelium. Anti-Prox-1 reacted positively with canine control tissues (lymph nodes, gingiva, nasal mucosa), but showed no staining in tissue sections of the dental pulp. The dog dental pulp contained no vascular structures lined with lymphatic endothelium. This suggests that drainage of interstitial fluid makes use of other routes, i.e. extravascular pathways.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Anat</journal-id><journal-id journal-id-type="publisher-id">joa</journal-id><journal-title-group><journal-title>Journal of Anatomy</journal-title></journal-title-group><issn pub-type="ppub">0021-8782</issn><issn pub-type="epub">1469-7580</issn><publisher><publisher-name>Blackwell Science Inc</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">20854283</article-id><article-id pub-id-type="pmc">3035865</article-id><article-id pub-id-type="doi">10.1111/j.1469-7580.2010.01298.x</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Articles</subject></subj-group></article-categories><title-group><article-title>Absence of lymphatic vessels in the dog dental pulp: an immunohistochemical study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Martin</surname><given-names>Anna</given-names></name></contrib><contrib contrib-type="author"><name><surname>Gasse</surname><given-names>Hagen</given-names></name></contrib><contrib contrib-type="author"><name><surname>Staszyk</surname><given-names>Carsten</given-names></name></contrib><aff><institution>Institute of Anatomy, University of Veterinary Medicine Hannover, Bischofsholer Damm</institution><addr-line>Hannover, Germany</addr-line></aff></contrib-group><author-notes><corresp id="cor1">Carsten Staszyk, Institute of Anatomy, University of Veterinary Medicine Hannover, Bischofsholer Damm, Hannover, Germany. E: <email>Carsten.Staszyk@tiho-hannover.de</email></corresp></author-notes><pub-date pub-type="ppub"><month>11</month><year>2010</year></pub-date><pub-date pub-type="epub"><day>13</day><month>9</month><year>2010</year></pub-date><volume>217</volume><issue>5</issue><fpage>609</fpage><lpage>615</lpage><history><date date-type="accepted"><day>11</day><month>8</month><year>2010</year></date></history><permissions><copyright-statement>Copyright © 2010 Anatomical Society of Great Britain and Ireland</copyright-statement></permissions><abstract><p>In spite of numerous investigations it has not been precisely determined whether lymphatic vessels are present in the dental pulp of dogs. Therefore, this study attempted a specific immunohistochemical detection of lymphatic endothelium. The canine teeth of 19 healthy beagle dogs were dissected into three segments (apical, intermediate and occlusal). After decalcification, specimens were embedded in paraffin wax and histologic cross-sections were stained immunohistochemically using a reliable antibody (anti-Prox-1) against the homeobox transcription factor Prox-1, which is located within the nucleus of lymphatic endothelium. Anti-Prox-1 reacted positively with canine control tissues (lymph nodes, gingiva, nasal mucosa), but showed no staining in tissue sections of the dental pulp. The dog dental pulp contained no vascular structures lined with lymphatic endothelium. This suggests that drainage of interstitial fluid makes use of other routes, i.e. extravascular pathways.</p></abstract><kwd-group><kwd>endodontium</kwd><kwd>interstitial fluid</kwd><kwd>lymphatic endothelium</kwd><kwd>Prox-1</kwd><kwd>teeth</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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