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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Breast Cancer Morbidity</title><author><name sortKey="Feiten, Stefan" sort="Feiten, Stefan" uniqKey="Feiten S" first="Stefan" last="Feiten">Stefan Feiten</name><affiliation><nlm:aff id="AFF1">Institute for Health Services Research in Oncology (InVO), Koblenz</nlm:aff></affiliation></author><author><name sortKey="Dunnebacke, Jan" sort="Dunnebacke, Jan" uniqKey="Dunnebacke J" first="Jan" last="Dünnebacke">Jan Dünnebacke</name><affiliation><nlm:aff id="AFF2">Breast Cancer Center Marienhof, Catholic Clinical Center Koblenz-Montabaur, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Heymanns, Jochen" sort="Heymanns, Jochen" uniqKey="Heymanns J" first="Jochen" last="Heymanns">Jochen Heymanns</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Koppler, Hubert" sort="Koppler, Hubert" uniqKey="Koppler H" first="Hubert" last="Köppler">Hubert Köppler</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Thomalla, Jorg" sort="Thomalla, Jorg" uniqKey="Thomalla J" first="Jörg" last="Thomalla">Jörg Thomalla</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Van Roye, Christoph" sort="Van Roye, Christoph" uniqKey="Van Roye C" first="Christoph" last="Van Roye">Christoph Van Roye</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Wey, Diana" sort="Wey, Diana" uniqKey="Wey D" first="Diana" last="Wey">Diana Wey</name><affiliation><nlm:aff id="AFF2">Breast Cancer Center Marienhof, Catholic Clinical Center Koblenz-Montabaur, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Weide, Rudolf" sort="Weide, Rudolf" uniqKey="Weide R" first="Rudolf" last="Weide">Rudolf Weide</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25145512</idno><idno type="pmc">4148709</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148709</idno><idno type="RBID">PMC:4148709</idno><idno type="doi">10.3238/arztebl.2014.0537</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002D93</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D93</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Breast Cancer Morbidity</title><author><name sortKey="Feiten, Stefan" sort="Feiten, Stefan" uniqKey="Feiten S" first="Stefan" last="Feiten">Stefan Feiten</name><affiliation><nlm:aff id="AFF1">Institute for Health Services Research in Oncology (InVO), Koblenz</nlm:aff></affiliation></author><author><name sortKey="Dunnebacke, Jan" sort="Dunnebacke, Jan" uniqKey="Dunnebacke J" first="Jan" last="Dünnebacke">Jan Dünnebacke</name><affiliation><nlm:aff id="AFF2">Breast Cancer Center Marienhof, Catholic Clinical Center Koblenz-Montabaur, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Heymanns, Jochen" sort="Heymanns, Jochen" uniqKey="Heymanns J" first="Jochen" last="Heymanns">Jochen Heymanns</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Koppler, Hubert" sort="Koppler, Hubert" uniqKey="Koppler H" first="Hubert" last="Köppler">Hubert Köppler</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Thomalla, Jorg" sort="Thomalla, Jorg" uniqKey="Thomalla J" first="Jörg" last="Thomalla">Jörg Thomalla</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Van Roye, Christoph" sort="Van Roye, Christoph" uniqKey="Van Roye C" first="Christoph" last="Van Roye">Christoph Van Roye</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Wey, Diana" sort="Wey, Diana" uniqKey="Wey D" first="Diana" last="Wey">Diana Wey</name><affiliation><nlm:aff id="AFF2">Breast Cancer Center Marienhof, Catholic Clinical Center Koblenz-Montabaur, Koblenz</nlm:aff></affiliation></author><author><name sortKey="Weide, Rudolf" sort="Weide, Rudolf" uniqKey="Weide R" first="Rudolf" last="Weide">Rudolf Weide</name><affiliation><nlm:aff id="AFF3">Outpatient Clinic for Hematology and Oncology, Koblenz</nlm:aff></affiliation></author></analytic><series><title level="j">Deutsches Ärzteblatt International</title><idno type="eISSN">1866-0452</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background</title><p>Many women have symptoms of various kinds after being treated for breast cancer. It is unclear how frequently these different side effects of treatment arise.</p></sec><sec id="st2"><title>Methods</title><p>All women who underwent surgery for breast cancer and subsequently received adjuvant systemic treatment in a single certified breast-cancer center from 2006 to 2010 were asked to fill out a standardized questionnaire. Medical data were retrieved from their charts and statistically analyzed together with the questionnaire responses. The questionnaire was also given to an age-adjusted control group.</p></sec><sec id="st3"><title>Results</title><p>734 questionnaires were filled out and returned (response rate, 70%). The mean interval from the diagnosis of breast cancer to the time of response to the questionnaire was 38 months. The median age at time of response to the questionnaire was 65 years (range, 30 to 91 years). The distribution of UICC stages at the time of initial diagnosis was as follows: I 46%, II 42%, III 12%. 78% of the patients underwent breat conserving surgery, 85% had radiotherapy, 85% had antihormonal treatment, and 49% had chemotherapy. 91% were satisfied or very satisfied with the outcome of surgery. 34% reported operation site pain; 35% reported limitations of shoulder or arm function. Younger patients suffered from emotional sequelae more than older ones did. 25% reported a change in their relationship with their spouse. Before being diagnosed with breast cancer, 9% had consulted a psychiatrist or psychotherapist; after the diagnosis, 19% did. 14% had taken psychoactive medication before the diagnosis, and 26% did afterward.</p></sec><sec id="st4"><title>Conclusion</title><p>Treatment for breast cancer has negative physical, emotional, and social effects on many patients. They suffer these effects to varying degrees depending on age, type of surgery, and systemic treatment.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Dtsch Arztebl Int</journal-id><journal-id journal-id-type="iso-abbrev">Dtsch Arztebl Int</journal-id><journal-id journal-id-type="publisher-id">Deutscher Arzte Verlag</journal-id><journal-title-group><journal-title>Deutsches Ärzteblatt International</journal-title></journal-title-group><issn pub-type="epub">1866-0452</issn><publisher><publisher-name>Deutscher Arzte Verlag</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25145512</article-id><article-id pub-id-type="pmc">4148709</article-id><article-id pub-id-type="doi">10.3238/arztebl.2014.0537</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Article</subject></subj-group></article-categories><title-group><article-title>Breast Cancer Morbidity</article-title><subtitle>Questionnaire Survey of Patients on the Long Term Effects of Disease and Adjuvant Therapy</subtitle></title-group><contrib-group><contrib contrib-type="author"><name><surname>Feiten</surname><given-names>Stefan</given-names></name><xref ref-type="corresp" rid="COR1">*</xref><xref ref-type="aff" rid="AFF1">1</xref></contrib><contrib contrib-type="author"><name><surname>Dünnebacke</surname><given-names>Jan</given-names></name><degrees>Dr. med.</degrees><xref ref-type="aff" rid="AFF2">2</xref></contrib><contrib contrib-type="author"><name><surname>Heymanns</surname><given-names>Jochen</given-names></name><degrees>Dr. med.</degrees><xref ref-type="aff" rid="AFF3">3</xref></contrib><contrib contrib-type="author"><name><surname>Köppler</surname><given-names>Hubert</given-names></name><degrees>Prof. Dr. med.</degrees><xref ref-type="aff" rid="AFF3">3</xref></contrib><contrib contrib-type="author"><name><surname>Thomalla</surname><given-names>Jörg</given-names></name><degrees>Dr. med.</degrees><xref ref-type="aff" rid="AFF3">3</xref></contrib><contrib contrib-type="author"><name><surname>van Roye</surname><given-names>Christoph</given-names></name><degrees>Dr. med.</degrees><xref ref-type="aff" rid="AFF3">3</xref></contrib><contrib contrib-type="author"><name><surname>Wey</surname><given-names>Diana</given-names></name><xref ref-type="aff" rid="AFF2">2</xref></contrib><contrib contrib-type="author"><name><surname>Weide</surname><given-names>Rudolf</given-names></name><degrees>Prof. Dr. med.</degrees><xref ref-type="aff" rid="AFF3">3</xref></contrib><aff id="AFF1"><label>1</label>Institute for Health Services Research in Oncology (InVO), Koblenz</aff><aff id="AFF2"><label>2</label>Breast Cancer Center Marienhof, Catholic Clinical Center Koblenz-Montabaur, Koblenz</aff><aff id="AFF3"><label>3</label>Outpatient Clinic for Hematology and Oncology, Koblenz</aff></contrib-group><author-notes><corresp id="COR1">*Institut für Versorgungsforschung in der Onkologie, Neversstr. 5, 56068 Koblenz, Germany, <email>s.feiten@invo-koblenz.de</email></corresp></author-notes><pub-date pub-type="ppub"><month>8</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>04</day><month>8</month><year>2014</year></pub-date><volume>111</volume><issue>31-32</issue><fpage>537</fpage><lpage>544</lpage><history><date date-type="received"><day>5</day><month>3</month><year>2014</year></date><date date-type="accepted"><day>28</day><month>5</month><year>2014</year></date></history><abstract abstract-type="executive-summary"><sec id="st1"><title>Background</title><p>Many women have symptoms of various kinds after being treated for breast cancer. It is unclear how frequently these different side effects of treatment arise.</p></sec><sec id="st2"><title>Methods</title><p>All women who underwent surgery for breast cancer and subsequently received adjuvant systemic treatment in a single certified breast-cancer center from 2006 to 2010 were asked to fill out a standardized questionnaire. Medical data were retrieved from their charts and statistically analyzed together with the questionnaire responses. The questionnaire was also given to an age-adjusted control group.</p></sec><sec id="st3"><title>Results</title><p>734 questionnaires were filled out and returned (response rate, 70%). The mean interval from the diagnosis of breast cancer to the time of response to the questionnaire was 38 months. The median age at time of response to the questionnaire was 65 years (range, 30 to 91 years). The distribution of UICC stages at the time of initial diagnosis was as follows: I 46%, II 42%, III 12%. 78% of the patients underwent breat conserving surgery, 85% had radiotherapy, 85% had antihormonal treatment, and 49% had chemotherapy. 91% were satisfied or very satisfied with the outcome of surgery. 34% reported operation site pain; 35% reported limitations of shoulder or arm function. Younger patients suffered from emotional sequelae more than older ones did. 25% reported a change in their relationship with their spouse. Before being diagnosed with breast cancer, 9% had consulted a psychiatrist or psychotherapist; after the diagnosis, 19% did. 14% had taken psychoactive medication before the diagnosis, and 26% did afterward.</p></sec><sec id="st4"><title>Conclusion</title><p>Treatment for breast cancer has negative physical, emotional, and social effects on many patients. They suffer these effects to varying degrees depending on age, type of surgery, and systemic treatment.</p></sec></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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