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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Extracellular–to–body cell mass ratio and subjective global assessment in head-and-neck cancers</title><author><name sortKey="Malecka Assalska, T" sort="Malecka Assalska, T" uniqKey="Malecka Assalska T" first="T." last="Małecka Assalska">T. Małecka Assalska</name><affiliation><nlm:aff id="af1-conc-21-e62">Physiology Department, Medical University of Lublin, Lublin, Poland.</nlm:aff></affiliation></author><author><name sortKey="Smole, A" sort="Smole, A" uniqKey="Smole A" first="A." last="Smole">A. Smole</name><affiliation><nlm:aff id="af2-conc-21-e62">Mathematics and Biostatistics Department, Medical University of Lublin, Lublin, Poland.</nlm:aff></affiliation></author><author><name sortKey="Morshed, K" sort="Morshed, K" uniqKey="Morshed K" first="K." last="Morshed">K. Morshed</name><affiliation><nlm:aff id="af3-conc-21-e62">Otolaryngology Department, Head and Neck Surgery, Medical University of Lublin, Lublin, Poland.</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24523622</idno><idno type="pmc">3921049</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921049</idno><idno type="RBID">PMC:3921049</idno><idno type="doi">10.3747/co.21.1671</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002D69</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002D69</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Extracellular–to–body cell mass ratio and subjective global assessment in head-and-neck cancers</title><author><name sortKey="Malecka Assalska, T" sort="Malecka Assalska, T" uniqKey="Malecka Assalska T" first="T." last="Małecka Assalska">T. Małecka Assalska</name><affiliation><nlm:aff id="af1-conc-21-e62">Physiology Department, Medical University of Lublin, Lublin, Poland.</nlm:aff></affiliation></author><author><name sortKey="Smole, A" sort="Smole, A" uniqKey="Smole A" first="A." last="Smole">A. Smole</name><affiliation><nlm:aff id="af2-conc-21-e62">Mathematics and Biostatistics Department, Medical University of Lublin, Lublin, Poland.</nlm:aff></affiliation></author><author><name sortKey="Morshed, K" sort="Morshed, K" uniqKey="Morshed K" first="K." last="Morshed">K. Morshed</name><affiliation><nlm:aff id="af3-conc-21-e62">Otolaryngology Department, Head and Neck Surgery, Medical University of Lublin, Lublin, Poland.</nlm:aff></affiliation></author></analytic><series><title level="j">Current Oncology</title><idno type="ISSN">1198-0052</idno><idno type="eISSN">1718-7729</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The ratio of extracellular mass to body cell mass (<sc>ecm/bcm</sc>), determined by bioelectrical impedance analysis, has been found to be a potentially useful indicator of nutrition status. Subjective global assessment (<sc>sga</sc>) is a subjective method of evaluating nutrition status in head-and-neck cancer. The present study was conducted to investigate the association between <sc>ecm/bcm</sc> and <sc>sga</sc> in head-and-neck cancer.</p></sec><sec><title>Methods</title><p>Patients were classified as either well-nourished or malnourished by <sc>sga</sc>. Bioelectrical impedance analysis was conducted on a population of 75 patients with histologically confirmed head-and-neck cancer, and the <sc>ecm/bcm</sc> was calculated. Receiver operating characteristic curves were estimated using the nonparametric method to determine an optimal cut-off value of the <sc>ecm/bcm</sc>.</p></sec><sec><title>Results</title><p>Compared with malnourished patients, those who were well-nourished had a statistically significantly lower <sc>ecm/bcm</sc> (1.11 vs. 1.28, <italic>p</italic> = 0.005). An <sc>ecm/bcm</sc> cut-off of 1.194 was 76% sensitive and 63% specific in detecting malnutrition.</p></sec><sec><title>Conclusions</title><p>The <sc>ecm/bcm</sc> can be an indicator that detects malnutrition in patients with head-and-neck cancer. Further observations are needed to validate the significance of the <sc>ecm/bcm</sc> and to monitor nutrition interventions.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Curr Oncol</journal-id><journal-id journal-id-type="iso-abbrev">Curr Oncol</journal-id><journal-id journal-id-type="publisher-id">CO</journal-id><journal-title-group><journal-title>Current Oncology</journal-title></journal-title-group><issn pub-type="ppub">1198-0052</issn><issn pub-type="epub">1718-7729</issn><publisher><publisher-name>Multimed Inc.</publisher-name><publisher-loc>66 Martin St. Milton, ON, Canada L9T 2R2</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24523622</article-id><article-id pub-id-type="pmc">3921049</article-id><article-id pub-id-type="doi">10.3747/co.21.1671</article-id><article-id pub-id-type="publisher-id">conc-21-e62</article-id><article-categories><subj-group subj-group-type="heading"><subject>Original Articles</subject><subj-group><subject>Nutrition in Oncology</subject></subj-group></subj-group></article-categories><title-group><article-title>Extracellular–to–body cell mass ratio and subjective global assessment in head-and-neck cancers</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Małecka–Massalska</surname><given-names>T.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="af1-conc-21-e62"><sup>*</sup></xref><xref ref-type="corresp" rid="c1-conc-21-e62"></xref></contrib><contrib contrib-type="author"><name><surname>Smoleń</surname><given-names>A.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="af2-conc-21-e62"><sup>†</sup></xref></contrib><contrib contrib-type="author"><name><surname>Morshed</surname><given-names>K.</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="af3-conc-21-e62"><sup>‡</sup></xref></contrib></contrib-group><aff id="af1-conc-21-e62"><label>*</label>Physiology Department, Medical University of Lublin, Lublin, Poland.</aff><aff id="af2-conc-21-e62"><label>†</label>Mathematics and Biostatistics Department, Medical University of Lublin, Lublin, Poland.</aff><aff id="af3-conc-21-e62"><label>‡</label>Otolaryngology Department, Head and Neck Surgery, Medical University of Lublin, Lublin, Poland.</aff><author-notes><corresp id="c1-conc-21-e62">Correspondence to: Teresa Małecka–Massalska, Physiology Department, Medical University of Lublin, Radziwiłłowska 11 Street, Lublin 20-080 Poland. E-mail: <email>tmalecka@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>2</month><year>2014</year></pub-date><volume>21</volume><issue>1</issue><fpage>e62</fpage><lpage>e66</lpage><permissions><copyright-statement>2014 Multimed Inc.</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract><sec><title>Background</title><p>The ratio of extracellular mass to body cell mass (<sc>ecm/bcm</sc>), determined by bioelectrical impedance analysis, has been found to be a potentially useful indicator of nutrition status. Subjective global assessment (<sc>sga</sc>) is a subjective method of evaluating nutrition status in head-and-neck cancer. The present study was conducted to investigate the association between <sc>ecm/bcm</sc> and <sc>sga</sc> in head-and-neck cancer.</p></sec><sec><title>Methods</title><p>Patients were classified as either well-nourished or malnourished by <sc>sga</sc>. Bioelectrical impedance analysis was conducted on a population of 75 patients with histologically confirmed head-and-neck cancer, and the <sc>ecm/bcm</sc> was calculated. Receiver operating characteristic curves were estimated using the nonparametric method to determine an optimal cut-off value of the <sc>ecm/bcm</sc>.</p></sec><sec><title>Results</title><p>Compared with malnourished patients, those who were well-nourished had a statistically significantly lower <sc>ecm/bcm</sc> (1.11 vs. 1.28, <italic>p</italic> = 0.005). An <sc>ecm/bcm</sc> cut-off of 1.194 was 76% sensitive and 63% specific in detecting malnutrition.</p></sec><sec><title>Conclusions</title><p>The <sc>ecm/bcm</sc> can be an indicator that detects malnutrition in patients with head-and-neck cancer. Further observations are needed to validate the significance of the <sc>ecm/bcm</sc> and to monitor nutrition interventions.</p></sec></abstract><kwd-group><kwd>Head-and-neck cancer</kwd><kwd>bioelectrical impedance analysis</kwd><kwd>extracellular–to–body cell mass ratio</kwd><kwd>subjective global assessment</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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