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Malignant hyperthermia: considerations for the general surgeon

Identifieur interne : 002D28 ( Pmc/Corpus ); précédent : 002D27; suivant : 002D29

Malignant hyperthermia: considerations for the general surgeon

Auteurs : Jane E. Heggie

Source :

RBID : PMC:3684643

Abstract

Malignant hyperthermia is a potentially fatal genetic myopathy that presents when the patient is under anesthesia. It manifests as a hypermetabolic state involving tachycardia, hypercarbia, base deficit, rigidity and fever. Many of the hallmark traits of an acute malignant hyperthermic crisis overlap with signs and symptoms of an emergent abdominal condition. Historically, there has been a reluctance in local community hospitals to manage patients known to be susceptible to malignant hyperthemia, and this is a source of frustration for many families in which there is a history of this condition. This article outlines the diagnosis and management of an acute malignant hyperthermic crisis from the viewpoint of a community general surgeon and provides a review of the management of patients known to be susceptible to this condition in the surgeon’s elective and emergent practice.


Url:
PubMed: 12387544
PubMed Central: 3684643

Links to Exploration step

PMC:3684643

Le document en format XML

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<title xml:lang="en">Malignant hyperthermia: considerations for the general surgeon</title>
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<title level="j">Canadian Journal of Surgery</title>
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<p>Malignant hyperthermia is a potentially fatal genetic myopathy that presents when the patient is under anesthesia. It manifests as a hypermetabolic state involving tachycardia, hypercarbia, base deficit, rigidity and fever. Many of the hallmark traits of an acute malignant hyperthermic crisis overlap with signs and symptoms of an emergent abdominal condition. Historically, there has been a reluctance in local community hospitals to manage patients known to be susceptible to malignant hyperthemia, and this is a source of frustration for many families in which there is a history of this condition. This article outlines the diagnosis and management of an acute malignant hyperthermic crisis from the viewpoint of a community general surgeon and provides a review of the management of patients known to be susceptible to this condition in the surgeon’s elective and emergent practice.</p>
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<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
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<journal-id journal-id-type="nlm-ta">Can J Surg</journal-id>
<journal-id journal-id-type="iso-abbrev">Can J Surg</journal-id>
<journal-id journal-id-type="publisher-id">0372715</journal-id>
<journal-title-group>
<journal-title>Canadian Journal of Surgery</journal-title>
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<issn pub-type="ppub">0008-428X</issn>
<issn pub-type="epub">1488-2310</issn>
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<publisher-name>Canadian Medical Association</publisher-name>
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<article-id pub-id-type="pmid">12387544</article-id>
<article-id pub-id-type="pmc">3684643</article-id>
<article-id pub-id-type="publisher-id">0450369</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Surgical Biology for the Clinician</subject>
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<title-group>
<article-title>Malignant hyperthermia: considerations for the general surgeon</article-title>
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<name>
<surname>Heggie</surname>
<given-names>Jane E.</given-names>
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<degrees>MD</degrees>
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<aff id="af1-0450369">Department of Anesthesia, Toronto General Hospital, University Health Network, Toronto, Ont.</aff>
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<author-notes>
<corresp id="c1-0450369">Correspondence to: Dr. Jane Heggie, Department of Anesthesia, Toronto General Hospital, University Health Network, EN3-425, Toronto ON M5G 2C4; fax 416 340-4896;
<email>jane.heggie@uhn.on.ca</email>
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<pub-date pub-type="ppub">
<month>10</month>
<year>2002</year>
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<volume>45</volume>
<issue>5</issue>
<fpage>369</fpage>
<lpage>372</lpage>
<history>
<date date-type="accepted">
<day>17</day>
<month>10</month>
<year>2001</year>
</date>
</history>
<permissions>
<copyright-statement>© 2002 Canadian Medical Association</copyright-statement>
<copyright-year>2002</copyright-year>
</permissions>
<abstract>
<p>Malignant hyperthermia is a potentially fatal genetic myopathy that presents when the patient is under anesthesia. It manifests as a hypermetabolic state involving tachycardia, hypercarbia, base deficit, rigidity and fever. Many of the hallmark traits of an acute malignant hyperthermic crisis overlap with signs and symptoms of an emergent abdominal condition. Historically, there has been a reluctance in local community hospitals to manage patients known to be susceptible to malignant hyperthemia, and this is a source of frustration for many families in which there is a history of this condition. This article outlines the diagnosis and management of an acute malignant hyperthermic crisis from the viewpoint of a community general surgeon and provides a review of the management of patients known to be susceptible to this condition in the surgeon’s elective and emergent practice.</p>
</abstract>
<trans-abstract xml:lang="fr">
<p>L’hyperthermie maligne est une myopathie d’origine génétique qui peut être mortelle et survient lorsque le patient est sous anesthésie. Cette myopathie se manifeste par un hypermétabolisme qui entraîne une tachycardie, une hypercarbie, un déficit de base, la rigidité et la fièvre. Beaucoup de caractéristiques d’une crise aiguë d’hyperthermie maligne ressemblent aux signes et aux symptômes d’un problème abdominal émergent. Les hôpitaux communautaires locaux ont toujours hésité à prendre en charge des patients dont la vulnérabilité à l’hyperthermie maligne est reconnue et il s’agit d’une source de frustration pour beaucoup de familles qui ont des antécédents à cet égard. Cet article décrit le diagnostic et la prise en charge d’une crise aiguë d’hyperthermie maligne du point de vue du chirurgien général communautaire et présente une revue de la prise en charge, dans la pratique élective et émergente du chirurgien, des patients dont la vulnérabilité à ce problème est reconnue.</p>
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