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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study</title><author><name sortKey="Williamson, Js" sort="Williamson, Js" uniqKey="Williamson J" first="Js" last="Williamson">Js Williamson</name><affiliation><nlm:aff id="au1"><institution>Royal Gwent Hospital</institution><addr-line>Newport, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Ingrams, D" sort="Ingrams, D" uniqKey="Ingrams D" first="D" last="Ingrams">D. Ingrams</name><affiliation><nlm:aff id="au1"><institution>Royal Gwent Hospital</institution><addr-line>Newport, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Jones, H" sort="Jones, H" uniqKey="Jones H" first="H" last="Jones">H. Jones</name><affiliation><nlm:aff id="au2"><institution>Royal Glamorgan Hospital</institution><addr-line>Llantrisant, UK</addr-line></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22041234</idno><idno type="pmc">3566683</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566683</idno><idno type="RBID">PMC:3566683</idno><idno type="doi">10.1308/147870811X13137608455253</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">002C21</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002C21</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study</title><author><name sortKey="Williamson, Js" sort="Williamson, Js" uniqKey="Williamson J" first="Js" last="Williamson">Js Williamson</name><affiliation><nlm:aff id="au1"><institution>Royal Gwent Hospital</institution><addr-line>Newport, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Ingrams, D" sort="Ingrams, D" uniqKey="Ingrams D" first="D" last="Ingrams">D. Ingrams</name><affiliation><nlm:aff id="au1"><institution>Royal Gwent Hospital</institution><addr-line>Newport, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Jones, H" sort="Jones, H" uniqKey="Jones H" first="H" last="Jones">H. Jones</name><affiliation><nlm:aff id="au2"><institution>Royal Glamorgan Hospital</institution><addr-line>Llantrisant, UK</addr-line></nlm:aff></affiliation></author></analytic><series><title level="j">Annals of The Royal College of Surgeons of England</title><idno type="ISSN">0035-8843</idno><idno type="eISSN">1478-7083</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>INTRODUCTION</title><p>Laryngeal cancer treatment inherently affects life's most basic functions and significantly affects quality of life (QOL). We aimed to identify which aspects of QOL and which patients are most affected by the various treatment options.</p></sec><sec><title>METHODS</title><p>The University of Washington Quality of Life (UW-QOL) questionnaire was administered to all patients with laryngeal cancer treated at a single institution over a seven-year period (2003–2010).</p></sec><sec><title>RESULTS</title><p>In total, 41 patients responded. All had been treated for squamous cell carcinoma of the larynx. Questionnaires were completed at a median of 18.5 months after treatment. The overall quality of life was 81.1/100 as assessed by the UW-QOL scale, with only 4.9% reporting ‘poor’ or worse QOL. Neither patient age nor time after treatment significantly affected any aspect of QOL. Patients undergoing primary radiotherapy reported the best QOL. Those undergoing chemoradiotherapy or combined surgical treatment and chemoradiotherapy reported the worst QOL, particularly in terms of social eating, taste and saliva production. Patients with a T stage ≥2 and those with nodal metastases reported a significantly worse QOL.</p></sec><sec><title>CONCLUSIONS</title><p>Overall, QOL in our patients was good. This study highlights the aspects of QOL most affected by various treatments for laryngeal cancer and identifies areas in which therapeutic intervention may be focused. It also provides information to guide clinicians when assisting patients to make informed decisions regarding treatment of their head and neck cancer.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann R Coll Surg Engl</journal-id><journal-id journal-id-type="iso-abbrev">Ann R Coll Surg Engl</journal-id><journal-id journal-id-type="publisher-id">rcse</journal-id><journal-title-group><journal-title>Annals of The Royal College of Surgeons of England</journal-title></journal-title-group><issn pub-type="ppub">0035-8843</issn><issn pub-type="epub">1478-7083</issn><publisher><publisher-name>The Royal College of Surgeons of England</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22041234</article-id><article-id pub-id-type="pmc">3566683</article-id><article-id pub-id-type="doi">10.1308/147870811X13137608455253</article-id><article-categories><subj-group subj-group-type="heading"><subject>Head and Neck</subject></subj-group></article-categories><title-group><article-title>Quality of life after treatment of laryngeal carcinoma: a single centre cross-sectional study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Williamson</surname><given-names>JS</given-names></name><xref ref-type="aff" rid="au1">1</xref></contrib><contrib contrib-type="author"><name><surname>Ingrams</surname><given-names>D</given-names></name><xref ref-type="aff" rid="au1">1</xref></contrib><contrib contrib-type="author"><name><surname>Jones</surname><given-names>H</given-names></name><xref ref-type="aff" rid="au2">2</xref></contrib><aff id="au1"><label>1</label><institution>Royal Gwent Hospital</institution><addr-line>Newport, UK</addr-line></aff><aff id="au2"><label>2</label><institution>Royal Glamorgan Hospital</institution><addr-line>Llantrisant, UK</addr-line></aff></contrib-group><author-notes><corresp><bold>CORRESPONDENCE TO Jeremy Williamson</bold>, Department of ENT, Royal Gwent Hospital, Cardiff Road, Newport, NP20 2UB, UK <email>jswilliamson@doctors.org.uk</email></corresp></author-notes><pub-date pub-type="ppub"><month>11</month><year>2011</year></pub-date><volume>93</volume><issue>8</issue><fpage>591</fpage><lpage>595</lpage><history><date date-type="accepted"><day>09</day><month>8</month><year>2011</year></date></history><permissions><copyright-statement>Copyright © 2011 by the Annals of The Royal College of Surgeons of England</copyright-statement><copyright-year>2011</copyright-year></permissions><abstract><sec><title>INTRODUCTION</title><p>Laryngeal cancer treatment inherently affects life's most basic functions and significantly affects quality of life (QOL). We aimed to identify which aspects of QOL and which patients are most affected by the various treatment options.</p></sec><sec><title>METHODS</title><p>The University of Washington Quality of Life (UW-QOL) questionnaire was administered to all patients with laryngeal cancer treated at a single institution over a seven-year period (2003–2010).</p></sec><sec><title>RESULTS</title><p>In total, 41 patients responded. All had been treated for squamous cell carcinoma of the larynx. Questionnaires were completed at a median of 18.5 months after treatment. The overall quality of life was 81.1/100 as assessed by the UW-QOL scale, with only 4.9% reporting ‘poor’ or worse QOL. Neither patient age nor time after treatment significantly affected any aspect of QOL. Patients undergoing primary radiotherapy reported the best QOL. Those undergoing chemoradiotherapy or combined surgical treatment and chemoradiotherapy reported the worst QOL, particularly in terms of social eating, taste and saliva production. Patients with a T stage ≥2 and those with nodal metastases reported a significantly worse QOL.</p></sec><sec><title>CONCLUSIONS</title><p>Overall, QOL in our patients was good. This study highlights the aspects of QOL most affected by various treatments for laryngeal cancer and identifies areas in which therapeutic intervention may be focused. It also provides information to guide clinicians when assisting patients to make informed decisions regarding treatment of their head and neck cancer.</p></sec></abstract><kwd-group><kwd>University Washington Quality of Life</kwd><kwd>Head and neck neoplasm</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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