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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">EFFECTS OF LIVER DISEASE ON THE WELL-BEING OF PERSONS LIVING WITH HIV</title><author><name sortKey="Henderson, Wendy A" sort="Henderson, Wendy A" uniqKey="Henderson W" first="Wendy A." last="Henderson">Wendy A. Henderson</name><affiliation><nlm:aff id="A1">Staff Scientist, Biobehavioral Unit, Symptom Management Branch, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Fall Dickson, Jane M" sort="Fall Dickson, Jane M" uniqKey="Fall Dickson J" first="Jane M." last="Fall-Dickson">Jane M. Fall-Dickson</name><affiliation><nlm:aff id="A2">Investigator, Mucosal Injury Unit, Symptom Management Branch, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Schlenk, Elizabeth A" sort="Schlenk, Elizabeth A" uniqKey="Schlenk E" first="Elizabeth A." last="Schlenk">Elizabeth A. Schlenk</name><affiliation><nlm:aff id="A3">Assistant Professor, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</nlm:aff></affiliation></author><author><name sortKey="Kim, Kevin H" sort="Kim, Kevin H" uniqKey="Kim K" first="Kevin H." last="Kim">Kevin H. Kim</name><affiliation><nlm:aff id="A4">Assistant Professor, Psychology in Education, University of Pittsburgh, School of Education, Pittsburgh, PA 15260, USA</nlm:aff></affiliation></author><author><name sortKey="Matthews, Judith T" sort="Matthews, Judith T" uniqKey="Matthews J" first="Judith T." last="Matthews">Judith T. Matthews</name><affiliation><nlm:aff id="A3">Assistant Professor, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</nlm:aff></affiliation></author><author><name sortKey="Erlen, Judith A" sort="Erlen, Judith A" uniqKey="Erlen J" first="Judith A." last="Erlen">Judith A. Erlen</name><affiliation><nlm:aff id="A5">Professor, PhD Coordinator, and Interim Chair, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18762144</idno><idno type="pmc">2577288</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577288</idno><idno type="RBID">PMC:2577288</idno><idno type="doi">10.1016/j.jana.2008.05.004</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">002908</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002908</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">EFFECTS OF LIVER DISEASE ON THE WELL-BEING OF PERSONS LIVING WITH HIV</title><author><name sortKey="Henderson, Wendy A" sort="Henderson, Wendy A" uniqKey="Henderson W" first="Wendy A." last="Henderson">Wendy A. Henderson</name><affiliation><nlm:aff id="A1">Staff Scientist, Biobehavioral Unit, Symptom Management Branch, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Fall Dickson, Jane M" sort="Fall Dickson, Jane M" uniqKey="Fall Dickson J" first="Jane M." last="Fall-Dickson">Jane M. Fall-Dickson</name><affiliation><nlm:aff id="A2">Investigator, Mucosal Injury Unit, Symptom Management Branch, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA</nlm:aff></affiliation></author><author><name sortKey="Schlenk, Elizabeth A" sort="Schlenk, Elizabeth A" uniqKey="Schlenk E" first="Elizabeth A." last="Schlenk">Elizabeth A. Schlenk</name><affiliation><nlm:aff id="A3">Assistant Professor, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</nlm:aff></affiliation></author><author><name sortKey="Kim, Kevin H" sort="Kim, Kevin H" uniqKey="Kim K" first="Kevin H." last="Kim">Kevin H. Kim</name><affiliation><nlm:aff id="A4">Assistant Professor, Psychology in Education, University of Pittsburgh, School of Education, Pittsburgh, PA 15260, USA</nlm:aff></affiliation></author><author><name sortKey="Matthews, Judith T" sort="Matthews, Judith T" uniqKey="Matthews J" first="Judith T." last="Matthews">Judith T. Matthews</name><affiliation><nlm:aff id="A3">Assistant Professor, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</nlm:aff></affiliation></author><author><name sortKey="Erlen, Judith A" sort="Erlen, Judith A" uniqKey="Erlen J" first="Judith A." last="Erlen">Judith A. Erlen</name><affiliation><nlm:aff id="A5">Professor, PhD Coordinator, and Interim Chair, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</nlm:aff></affiliation></author></analytic><series><title level="j">The Journal of the Association of Nurses in AIDS Care : JANAC</title><idno type="ISSN">1055-3290</idno><idno type="eISSN">1552-6917</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Clinical evidence suggests that patients with liver disease and HIV have poorer quality of life (QOL). Because little research exists to support this observation, this study examined the relationships between people with HIV and liver disorders and their QOL. Cella's multidimensional (functional, social, emotional, physical) conceptualization of QOL guided this study. The sample included 80 participants with liver disorders and HIV; 48.8% had chronic or permanent hepatitis. Cella's 4 dimensions significantly correlated with QOL: functional, <italic>r</italic> = .329, <italic>p</italic> <<. 01; social, <italic>r</italic> = .636, <italic>p</italic> < .01; emotional, <italic>r</italic> = −.549, <italic>p</italic> < .01; and physical, <italic>r</italic> = −480, <italic>p</italic> < .01. Linear regression analysis with QOL as the dependent variable and the 4 dimensions as predictors resulted in significant associations explaining approximately 50% of the variance (<italic>R2</italic> = .532). Confirmatory factor analysis supported Cella's model with the 4 sub-domains loading on 1 factor (QOL). Understanding the multiple dimensions of QOL may assist in developing interventions for patients with HIV and co-morbid liver disorders.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9111870</journal-id><journal-id journal-id-type="pubmed-jr-id">1225</journal-id><journal-id journal-id-type="nlm-ta">J Assoc Nurses AIDS Care</journal-id><journal-title>The Journal of the Association of Nurses in AIDS Care : JANAC</journal-title><issn pub-type="ppub">1055-3290</issn><issn pub-type="epub">1552-6917</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18762144</article-id><article-id pub-id-type="pmc">2577288</article-id><article-id pub-id-type="manuscript">NIHMS69270</article-id><article-id pub-id-type="doi">10.1016/j.jana.2008.05.004</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>EFFECTS OF LIVER DISEASE ON THE WELL-BEING OF PERSONS LIVING WITH HIV</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Henderson</surname><given-names>Wendy A.</given-names></name><degrees>PhD, MSN, CRNP, RN</degrees><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Fall-Dickson</surname><given-names>Jane M.</given-names></name><degrees>PhD, RN</degrees><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Schlenk</surname><given-names>Elizabeth A.</given-names></name><degrees>PhD, RN</degrees><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Kim</surname><given-names>Kevin H.</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Matthews</surname><given-names>Judith T.</given-names></name><degrees>PhD, MPH, RN</degrees><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Erlen</surname><given-names>Judith A.</given-names></name><degrees>PhD, RN, FAAN</degrees><xref ref-type="aff" rid="A5">5</xref></contrib></contrib-group><aff id="A1"><label>1</label>Staff Scientist, Biobehavioral Unit, Symptom Management Branch, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA</aff><aff id="A2"><label>2</label>Investigator, Mucosal Injury Unit, Symptom Management Branch, National Institute of Nursing Research, National Institutes of Health, Bethesda, MD 20892, USA</aff><aff id="A3"><label>3</label>Assistant Professor, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</aff><aff id="A4"><label>4</label>Assistant Professor, Psychology in Education, University of Pittsburgh, School of Education, Pittsburgh, PA 15260, USA</aff><aff id="A5"><label>5</label>Professor, PhD Coordinator, and Interim Chair, Department of Health and Community Systems, University of Pittsburgh, School of Nursing, Pittsburgh, PA 15261, USA</aff><author-notes><corresp id="cor1">Correspondence should be addressed to: Wendy A. Henderson, PhD, MSN, CRNP, RN, Biobehavioral Unit, Symptom Management Branch, Intramural Research Division, National Institute of Nursing Research, National Institutes of Health/DHHS, 10 Center Drive, Clinical Research Center, 2-1339, Bethesda, MD 20892, Phone: 301.451.9534, Fax: 301.480.1413, <email>hendersw@mail.nih.gov</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>12</day><month>9</month><year>2008</year></pub-date><pub-date pub-type="ppub"><year>2008</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>9</month><year>2009</year></pub-date><volume>19</volume><issue>5</issue><fpage>368</fpage><lpage>374</lpage><abstract><p id="P1">Clinical evidence suggests that patients with liver disease and HIV have poorer quality of life (QOL). Because little research exists to support this observation, this study examined the relationships between people with HIV and liver disorders and their QOL. Cella's multidimensional (functional, social, emotional, physical) conceptualization of QOL guided this study. The sample included 80 participants with liver disorders and HIV; 48.8% had chronic or permanent hepatitis. Cella's 4 dimensions significantly correlated with QOL: functional, <italic>r</italic> = .329, <italic>p</italic> <<. 01; social, <italic>r</italic> = .636, <italic>p</italic> < .01; emotional, <italic>r</italic> = −.549, <italic>p</italic> < .01; and physical, <italic>r</italic> = −480, <italic>p</italic> < .01. Linear regression analysis with QOL as the dependent variable and the 4 dimensions as predictors resulted in significant associations explaining approximately 50% of the variance (<italic>R2</italic> = .532). Confirmatory factor analysis supported Cella's model with the 4 sub-domains loading on 1 factor (QOL). Understanding the multiple dimensions of QOL may assist in developing interventions for patients with HIV and co-morbid liver disorders.</p></abstract><kwd-group><kwd>HIV</kwd><kwd>liver disease</kwd><kwd>quality of life</kwd><kwd>well-being</kwd></kwd-group><contract-num rid="RR1">TL1 RR024155-01</contract-num><contract-num rid="NR1">R01 NR004749-10</contract-num><contract-num rid="NR1">P30 NR003924-149004</contract-num><contract-num rid="PHS2">NIH0013513879</contract-num><contract-sponsor id="RR1">National Center for Research Resources : NCRR</contract-sponsor><contract-sponsor id="NR1">National Institute of Nursing Research : NINR</contract-sponsor><contract-sponsor id="PHS2">NIH Intramural Employee : PHS</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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