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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Isolated Kaposi Sarcoma in two HIV negative patients</title>
<author><name sortKey="Seleit, Iman" sort="Seleit, Iman" uniqKey="Seleit I" first="Iman" last="Seleit">Iman Seleit</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Attia, Abdalla" sort="Attia, Abdalla" uniqKey="Attia A" first="Abdalla" last="Attia">Abdalla Attia</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Maraee, Alaa" sort="Maraee, Alaa" uniqKey="Maraee A" first="Alaa" last="Maraee">Alaa Maraee</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Samaka, Rehab" sort="Samaka, Rehab" uniqKey="Samaka R" first="Rehab" last="Samaka">Rehab Samaka</name>
<affiliation><nlm:aff id="A2">Department of Pathology, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bakry, Ola" sort="Bakry, Ola" uniqKey="Bakry O" first="Ola" last="Bakry">Ola Bakry</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eid, Emad" sort="Eid, Emad" uniqKey="Eid E" first="Emad" last="Eid">Emad Eid</name>
<affiliation><nlm:aff id="A3">Department of Microbiology, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21894251</idno>
<idno type="pmc">3163357</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163357</idno>
<idno type="RBID">PMC:3163357</idno>
<idno type="doi">10.3315/jdcr.2011.1067</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">002065</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002065</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Isolated Kaposi Sarcoma in two HIV negative patients</title>
<author><name sortKey="Seleit, Iman" sort="Seleit, Iman" uniqKey="Seleit I" first="Iman" last="Seleit">Iman Seleit</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Attia, Abdalla" sort="Attia, Abdalla" uniqKey="Attia A" first="Abdalla" last="Attia">Abdalla Attia</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Maraee, Alaa" sort="Maraee, Alaa" uniqKey="Maraee A" first="Alaa" last="Maraee">Alaa Maraee</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Samaka, Rehab" sort="Samaka, Rehab" uniqKey="Samaka R" first="Rehab" last="Samaka">Rehab Samaka</name>
<affiliation><nlm:aff id="A2">Department of Pathology, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Bakry, Ola" sort="Bakry, Ola" uniqKey="Bakry O" first="Ola" last="Bakry">Ola Bakry</name>
<affiliation><nlm:aff id="A1">Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Eid, Emad" sort="Eid, Emad" uniqKey="Eid E" first="Emad" last="Eid">Emad Eid</name>
<affiliation><nlm:aff id="A3">Department of Microbiology, Faculty of Medicine, Menoufiya University, Egypt</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of Dermatological Case Reports</title>
<idno type="eISSN">1898-7249</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background</title>
<p>Kaposi sarcoma (KS) is a neoplasm of the endothelial cells. It often manifests with multiple vascular nodules on the skin and other organs. It is a systemic, malignant and multifactorial disease and has a variable course. There are four types: classic, endemic, iatrogenic and HIV-associated. The primary presentation on the penis and face is uncommon and is mainly observed in HIV-positive patients. Multiple treatment modalities are used including surgery, cryotherapy, electrosurgery, laser and radiation therapy.</p>
</sec>
<sec id="st2"><title>Main observation</title>
<p>The authors present two cases of isolated Kaposi sarcoma in HIV negative, human herpes virus 8 (HHV-8) positive non immunocompromised patients. One case with facial KS and the other one with penile KS. Both were treated surgically with no recurrence in the following 6 months of the follow up period.</p>
</sec>
<sec id="st3"><title>Conclusions</title>
<p>Kaposi sarcoma is rare in HIV negative patients and is associated with HHV-8 infection. Lesions are usually solitary and can be treated surgically. It should be included in the differential diagnoses of penile and facial lesions that are clinically suspecious and resistent to therapy.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="case-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Dermatol Case Rep</journal-id>
<journal-id journal-id-type="publisher-id">jdcr</journal-id>
<journal-title-group><journal-title>Journal of Dermatological Case Reports</journal-title>
</journal-title-group>
<issn pub-type="epub">1898-7249</issn>
<publisher><publisher-name>Specjalisci Dermatolodzy</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">21894251</article-id>
<article-id pub-id-type="pmc">3163357</article-id>
<article-id pub-id-type="doi">10.3315/jdcr.2011.1067</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Isolated Kaposi Sarcoma in two HIV negative patients</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Seleit</surname>
<given-names>Iman</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Attia</surname>
<given-names>Abdalla</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Maraee</surname>
<given-names>Alaa</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Samaka</surname>
<given-names>Rehab</given-names>
</name>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Bakry</surname>
<given-names>Ola</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="corresp" rid="COR1">*</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Eid</surname>
<given-names>Emad</given-names>
</name>
<xref ref-type="aff" rid="A3">3</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt</aff>
<aff id="A2"><label>2</label>
Department of Pathology, Faculty of Medicine, Menoufiya University, Egypt</aff>
<aff id="A3"><label>3</label>
Department of Microbiology, Faculty of Medicine, Menoufiya University, Egypt</aff>
<author-notes><corresp id="COR1"><label>*</label>
<bold>Corresponding author:</bold>
Ola Bakry, Department of Dermatology, Andrology and S.T.Ds, Faculty of Medicine, Menoufiya University, Egypt. E-mail: <email>drola_2007@yahoo.com</email>
.
</corresp>
</author-notes>
<pub-date pub-type="collection"><day>6</day>
<month>6</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub"><day>6</day>
<month>6</month>
<year>2011</year>
</pub-date>
<volume>5</volume>
<issue>2</issue>
<fpage>24</fpage>
<lpage>26</lpage>
<history><date date-type="received"><day>10</day>
<month>3</month>
<year>2011</year>
</date>
<date date-type="accepted"><day>28</day>
<month>3</month>
<year>2011</year>
</date>
</history>
<permissions><copyright-statement>Copyright: © 2011 Specjalisci Dermatolodzy</copyright-statement>
<copyright-year>2011</copyright-year>
</permissions>
<abstract abstract-type="executive-summary"><sec id="st1"><title>Background</title>
<p>Kaposi sarcoma (KS) is a neoplasm of the endothelial cells. It often manifests with multiple vascular nodules on the skin and other organs. It is a systemic, malignant and multifactorial disease and has a variable course. There are four types: classic, endemic, iatrogenic and HIV-associated. The primary presentation on the penis and face is uncommon and is mainly observed in HIV-positive patients. Multiple treatment modalities are used including surgery, cryotherapy, electrosurgery, laser and radiation therapy.</p>
</sec>
<sec id="st2"><title>Main observation</title>
<p>The authors present two cases of isolated Kaposi sarcoma in HIV negative, human herpes virus 8 (HHV-8) positive non immunocompromised patients. One case with facial KS and the other one with penile KS. Both were treated surgically with no recurrence in the following 6 months of the follow up period.</p>
</sec>
<sec id="st3"><title>Conclusions</title>
<p>Kaposi sarcoma is rare in HIV negative patients and is associated with HHV-8 infection. Lesions are usually solitary and can be treated surgically. It should be included in the differential diagnoses of penile and facial lesions that are clinically suspecious and resistent to therapy.</p>
</sec>
</abstract>
<kwd-group kwd-group-type="author"><kwd>face</kwd>
<kwd>HIV</kwd>
<kwd>Kaposi sarcoma</kwd>
<kwd>nodule</kwd>
<kwd>penis</kwd>
<kwd>tumor</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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