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<titleStmt>
<title xml:lang="en">Pseudosarcoma of the Thigh: A Rare Case of Massive Localized Lymphedema</title>
<author>
<name sortKey="Bahrami, Arash" sort="Bahrami, Arash" uniqKey="Bahrami A" first="Arash" last="Bahrami">Arash Bahrami</name>
<affiliation>
<nlm:aff id="aff1">Texas College of Osteopathic Medicine, Fort Worth, Texas, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ronaghan, Joseph Edward" sort="Ronaghan, Joseph Edward" uniqKey="Ronaghan J" first="Joseph Edward" last="Ronaghan">Joseph Edward Ronaghan</name>
<affiliation>
<nlm:aff id="aff2">Department of Surgery, University of North Texas Health Science Center, Fort Worth, Texas, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="O Yurvati, A H" sort="O Yurvati, A H" uniqKey="O Yurvati A" first="A. H." last="O-Yurvati">A. H. O-Yurvati</name>
<affiliation>
<nlm:aff id="aff2">Department of Surgery, University of North Texas Health Science Center, Fort Worth, Texas, USA</nlm:aff>
</affiliation>
</author>
</titleStmt>
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<idno type="wicri:source">PMC</idno>
<idno type="pmid">25785328</idno>
<idno type="pmc">4370536</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370536</idno>
<idno type="RBID">PMC:4370536</idno>
<idno type="doi">10.9738/INTSURG-D-14-00077.1</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">002040</idno>
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<title xml:lang="en" level="a" type="main">Pseudosarcoma of the Thigh: A Rare Case of Massive Localized Lymphedema</title>
<author>
<name sortKey="Bahrami, Arash" sort="Bahrami, Arash" uniqKey="Bahrami A" first="Arash" last="Bahrami">Arash Bahrami</name>
<affiliation>
<nlm:aff id="aff1">Texas College of Osteopathic Medicine, Fort Worth, Texas, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Ronaghan, Joseph Edward" sort="Ronaghan, Joseph Edward" uniqKey="Ronaghan J" first="Joseph Edward" last="Ronaghan">Joseph Edward Ronaghan</name>
<affiliation>
<nlm:aff id="aff2">Department of Surgery, University of North Texas Health Science Center, Fort Worth, Texas, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="O Yurvati, A H" sort="O Yurvati, A H" uniqKey="O Yurvati A" first="A. H." last="O-Yurvati">A. H. O-Yurvati</name>
<affiliation>
<nlm:aff id="aff2">Department of Surgery, University of North Texas Health Science Center, Fort Worth, Texas, USA</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">International Surgery</title>
<idno type="ISSN">0020-8868</idno>
<imprint>
<date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
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<front>
<div type="abstract" xml:lang="en">
<p>Massive localized lymphedema, also called pseudosarcoma, is a rare condition associated with morbid obesity. Accurate identification of this entity helps the physician make the distinction between this condition and other soft tissue tumors, especially with the increasing rate of obesity worldwide. Obesity and increased caloric intake lead to storage of the excess energy in the form of adipose tissue. The excess adipose tissue disturbs the lymphatic vessels, leading to massive edema localized mostly in the lower extremity, reaching a substantial size and weight that interferes with the quality of life of the individual in question. The mass can cause cosmetic but more importantly functional and structural defects, leading to altered biomechanics with increased risk of deep vein thromboembolism. Below is a presentation of a patient presenting with complaint of a massive medial thigh mass. After much investigation, consultation, and use of diagnostic radiologic modalities it was diagnosed as what is referred to in the literature as massive localized lymphedema, or pseudosarcoma. This mass was managed by surgical excision and the diagnosis was further confirmed by pathologic analysis. After the excision, our patient regained his ability to ambulate on his own, with the help of a rehabilitation program and physical therapy. Massive localized lymphedema needs to be on the differential diagnosis of any morbidly obese patient presenting with mass, especially in the lower extremities. Adequate knowledge about this condition enables the physician to make the distinction between pseudosarcoma and true soft tissue sarcomas.</p>
</div>
</front>
</TEI>
<pmc article-type="case-report">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Int Surg</journal-id>
<journal-id journal-id-type="iso-abbrev">Int Surg</journal-id>
<journal-id journal-id-type="publisher-id">insu</journal-id>
<journal-title-group>
<journal-title>International Surgery</journal-title>
</journal-title-group>
<issn pub-type="ppub">0020-8868</issn>
<publisher>
<publisher-name>The International College of Surgeons, World Federation of General Surgeons and Surgical Specialists, Inc.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">25785328</article-id>
<article-id pub-id-type="pmc">4370536</article-id>
<article-id pub-id-type="doi">10.9738/INTSURG-D-14-00077.1</article-id>
<article-id pub-id-type="sici">insu-100-04-10</article-id>
<article-id pub-id-type="other">INTSURG-D-14-00077</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>General Surgery & Hernia Surgery</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Pseudosarcoma of the Thigh: A Rare Case of Massive Localized Lymphedema</article-title>
<alt-title alt-title-type="runhead">PSEUDOSARCOMA</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Bahrami</surname>
<given-names>Arash</given-names>
</name>
<xref ref-type="aff" rid="aff1">1</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Ronaghan</surname>
<given-names>Joseph Edward</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>O-Yurvati</surname>
<given-names>A.H.</given-names>
</name>
<xref ref-type="aff" rid="aff2">2</xref>
</contrib>
<aff id="aff1">
<label>1</label>
Texas College of Osteopathic Medicine, Fort Worth, Texas, USA</aff>
<aff id="aff2">
<label>2</label>
Department of Surgery, University of North Texas Health Science Center, Fort Worth, Texas, USA</aff>
</contrib-group>
<author-notes>
<corresp id="cor1">Reprint requests: Albert H. Olivencia-Yurvati, DO, Department of Surgery, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107-2699. Tel.: 817 735 5450; Fax: 817 735 5454; E-mail:
<email>albert.yurvati@unthsc.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>3</month>
<year>2015</year>
</pub-date>
<volume>100</volume>
<issue>3</issue>
<fpage>461</fpage>
<lpage>465</lpage>
<permissions>
<copyright-statement>Copyright 2015 by the International College of Surgeons</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract>
<p>Massive localized lymphedema, also called pseudosarcoma, is a rare condition associated with morbid obesity. Accurate identification of this entity helps the physician make the distinction between this condition and other soft tissue tumors, especially with the increasing rate of obesity worldwide. Obesity and increased caloric intake lead to storage of the excess energy in the form of adipose tissue. The excess adipose tissue disturbs the lymphatic vessels, leading to massive edema localized mostly in the lower extremity, reaching a substantial size and weight that interferes with the quality of life of the individual in question. The mass can cause cosmetic but more importantly functional and structural defects, leading to altered biomechanics with increased risk of deep vein thromboembolism. Below is a presentation of a patient presenting with complaint of a massive medial thigh mass. After much investigation, consultation, and use of diagnostic radiologic modalities it was diagnosed as what is referred to in the literature as massive localized lymphedema, or pseudosarcoma. This mass was managed by surgical excision and the diagnosis was further confirmed by pathologic analysis. After the excision, our patient regained his ability to ambulate on his own, with the help of a rehabilitation program and physical therapy. Massive localized lymphedema needs to be on the differential diagnosis of any morbidly obese patient presenting with mass, especially in the lower extremities. Adequate knowledge about this condition enables the physician to make the distinction between pseudosarcoma and true soft tissue sarcomas.</p>
</abstract>
<kwd-group>
<title>Key words</title>
<kwd>Pseudosarcoma</kwd>
<kwd>Massive localized lymphedema</kwd>
<kwd>Lymphatics</kwd>
<kwd>Benign tumor</kwd>
<kwd>Obesity</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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