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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Therapy resistant idiopathic scleredema: an underlying pathology not always present</title>
<author><name sortKey="Kalfa, Melike" sort="Kalfa, Melike" uniqKey="Kalfa M" first="Melike" last="Kalfa">Melike Kalfa</name>
</author>
<author><name sortKey="Kocanao Ullar, Hayriye" sort="Kocanao Ullar, Hayriye" uniqKey="Kocanao Ullar H" first="Hayriye" last="Koçanao Ullar">Hayriye Koçanao Ullar</name>
</author>
<author><name sortKey="Zihni, Figen Yargucu" sort="Zihni, Figen Yargucu" uniqKey="Zihni F" first="Figen Yargucu" last="Zihni">Figen Yargucu Zihni</name>
</author>
<author><name sortKey="Karabulut, Gonca" sort="Karabulut, Gonca" uniqKey="Karabulut G" first="Gonca" last="Karabulut">Gonca Karabulut</name>
</author>
<author><name sortKey="Emmungil, Hakan" sort="Emmungil, Hakan" uniqKey="Emmungil H" first="Hakan" last="Emmungil">Hakan Emmungil</name>
</author>
<author><name sortKey=" Nal, Vedat" sort=" Nal, Vedat" uniqKey=" Nal V" first="Vedat" last=" Nal">Vedat Nal</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27708956</idno>
<idno type="pmc">5047231</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047231</idno>
<idno type="RBID">PMC:5047231</idno>
<idno type="doi">10.5152/eurjrheum.2015.0004</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">002029</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002029</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Therapy resistant idiopathic scleredema: an underlying pathology not always present</title>
<author><name sortKey="Kalfa, Melike" sort="Kalfa, Melike" uniqKey="Kalfa M" first="Melike" last="Kalfa">Melike Kalfa</name>
</author>
<author><name sortKey="Kocanao Ullar, Hayriye" sort="Kocanao Ullar, Hayriye" uniqKey="Kocanao Ullar H" first="Hayriye" last="Koçanao Ullar">Hayriye Koçanao Ullar</name>
</author>
<author><name sortKey="Zihni, Figen Yargucu" sort="Zihni, Figen Yargucu" uniqKey="Zihni F" first="Figen Yargucu" last="Zihni">Figen Yargucu Zihni</name>
</author>
<author><name sortKey="Karabulut, Gonca" sort="Karabulut, Gonca" uniqKey="Karabulut G" first="Gonca" last="Karabulut">Gonca Karabulut</name>
</author>
<author><name sortKey="Emmungil, Hakan" sort="Emmungil, Hakan" uniqKey="Emmungil H" first="Hakan" last="Emmungil">Hakan Emmungil</name>
</author>
<author><name sortKey=" Nal, Vedat" sort=" Nal, Vedat" uniqKey=" Nal V" first="Vedat" last=" Nal">Vedat Nal</name>
</author>
</analytic>
<series><title level="j">European Journal of Rheumatology</title>
<idno type="ISSN">2147-9720</idno>
<idno type="eISSN">2148-4279</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Scleredema is a rare connective tissue disorder of unknown pathogenesis. Three types of scleredema have been described, based on its association with postinfection, monoclonal gammopathy and diabetes mellitus. We report herein a case of scleredema which the diagnosis didn’t get specified. The patient was followed regularly for 13 years and did not respond to various combinations of immunosuppressants and psoralen plus ultraviolet A therapy. Treatment of scleredema is quite difficult and of limited success. At present, there is no proved treatment for this disease.</p>
</div>
</front>
</TEI>
<pmc article-type="case-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Eur J Rheumatol</journal-id>
<journal-id journal-id-type="iso-abbrev">Eur J Rheumatol</journal-id>
<journal-title-group><journal-title>European Journal of Rheumatology</journal-title>
</journal-title-group>
<issn pub-type="ppub">2147-9720</issn>
<issn pub-type="epub">2148-4279</issn>
<publisher><publisher-name>Medical Research and Education Association</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">27708956</article-id>
<article-id pub-id-type="pmc">5047231</article-id>
<article-id pub-id-type="doi">10.5152/eurjrheum.2015.0004</article-id>
<article-id pub-id-type="publisher-id">ejr-2-4-163</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group><article-title>Therapy resistant idiopathic scleredema: an underlying pathology not always present</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Kalfa</surname>
<given-names>Melike</given-names>
</name>
<xref ref-type="corresp" rid="c1-ejr-2-4-163"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Koçanaoğulları</surname>
<given-names>Hayriye</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Zihni</surname>
<given-names>Figen Yargucu</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Karabulut</surname>
<given-names>Gonca</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Emmungil</surname>
<given-names>Hakan</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>İnal</surname>
<given-names>Vedat</given-names>
</name>
</contrib>
<aff id="af1-ejr-2-4-163">Department of Internal Medicine, Division of Rheumatology, Ege University Faculty of Medicine, İzmir, Turkey</aff>
</contrib-group>
<author-notes><corresp id="c1-ejr-2-4-163">Address for Correspondence: Melike Kalfa, Ege Üniversitesi Tıp Fakültesi, İç Hastalıklar Anabilim Dalı, Romatoloji Bölümü, İzmir, Türkiye, E-mail: <email>melikek@yahoo.com</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><month>12</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="epub"><day>20</day>
<month>5</month>
<year>2015</year>
</pub-date>
<volume>2</volume>
<issue>4</issue>
<fpage>163</fpage>
<lpage>164</lpage>
<history><date date-type="received"><day>21</day>
<month>1</month>
<year>2015</year>
</date>
<date date-type="accepted"><day>10</day>
<month>2</month>
<year>2015</year>
</date>
</history>
<permissions><copyright-statement>Copyright 2015 © Medical Research and Education Association</copyright-statement>
<copyright-year>2015</copyright-year>
</permissions>
<abstract><p>Scleredema is a rare connective tissue disorder of unknown pathogenesis. Three types of scleredema have been described, based on its association with postinfection, monoclonal gammopathy and diabetes mellitus. We report herein a case of scleredema which the diagnosis didn’t get specified. The patient was followed regularly for 13 years and did not respond to various combinations of immunosuppressants and psoralen plus ultraviolet A therapy. Treatment of scleredema is quite difficult and of limited success. At present, there is no proved treatment for this disease.</p>
</abstract>
<kwd-group><kwd>Scleredema</kwd>
<kwd>methotrexate</kwd>
<kwd>PUVA</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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