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<title xml:lang="en">Congenital distichiasis: Histopathological report of 3 cases
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<author>
<name sortKey="Alkatan, Hind Manaa" sort="Alkatan, Hind Manaa" uniqKey="Alkatan H" first="Hind Manaa" last="Alkatan">Hind Manaa Alkatan</name>
<affiliation>
<nlm:aff id="af005">Departments of Ophthalmology & Pathology, King Saud University College of Medicine, Riyadh, Saudi Arabia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Galindo Ferreiro, Alicia" sort="Galindo Ferreiro, Alicia" uniqKey="Galindo Ferreiro A" first="Alicia" last="Galindo-Ferreiro">Alicia Galindo-Ferreiro</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="af015">Department of Ophthalmology, Rio Hortega University Hospital, Valladolid, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Maktabi, Azza" sort="Maktabi, Azza" uniqKey="Maktabi A" first="Azza" last="Maktabi">Azza Maktabi</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Galvez Ruiz, Alberto" sort="Galvez Ruiz, Alberto" uniqKey="Galvez Ruiz A" first="Alberto" last="Galvez-Ruiz">Alberto Galvez-Ruiz</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Schellini, Silvana" sort="Schellini, Silvana" uniqKey="Schellini S" first="Silvana" last="Schellini">Silvana Schellini</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="af020">Department of Ophthalmology, Faculdade de Medicina de Botucatu - UNESP, São Paulo, Brazil</nlm:aff>
</affiliation>
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<idno type="pmid">28860915</idno>
<idno type="pmc">5569325</idno>
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<idno type="doi">10.1016/j.sjopt.2017.05.003</idno>
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<title xml:lang="en" level="a" type="main">Congenital distichiasis: Histopathological report of 3 cases
<sup>
<xref ref-type="fn" rid="d31e29"></xref>
</sup>
</title>
<author>
<name sortKey="Alkatan, Hind Manaa" sort="Alkatan, Hind Manaa" uniqKey="Alkatan H" first="Hind Manaa" last="Alkatan">Hind Manaa Alkatan</name>
<affiliation>
<nlm:aff id="af005">Departments of Ophthalmology & Pathology, King Saud University College of Medicine, Riyadh, Saudi Arabia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Galindo Ferreiro, Alicia" sort="Galindo Ferreiro, Alicia" uniqKey="Galindo Ferreiro A" first="Alicia" last="Galindo-Ferreiro">Alicia Galindo-Ferreiro</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="af015">Department of Ophthalmology, Rio Hortega University Hospital, Valladolid, Spain</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Maktabi, Azza" sort="Maktabi, Azza" uniqKey="Maktabi A" first="Azza" last="Maktabi">Azza Maktabi</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Galvez Ruiz, Alberto" sort="Galvez Ruiz, Alberto" uniqKey="Galvez Ruiz A" first="Alberto" last="Galvez-Ruiz">Alberto Galvez-Ruiz</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Schellini, Silvana" sort="Schellini, Silvana" uniqKey="Schellini S" first="Silvana" last="Schellini">Silvana Schellini</name>
<affiliation>
<nlm:aff id="af010">Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="af020">Department of Ophthalmology, Faculdade de Medicina de Botucatu - UNESP, São Paulo, Brazil</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Saudi Journal of Ophthalmology</title>
<idno type="ISSN">1319-4534</idno>
<imprint>
<date when="2017">2017</date>
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<front>
<div type="abstract" xml:lang="en">
<p>Distichiasis is a condition clinically presenting as partial or complete accessory row of lashes that emerges from the meibomian glands orifices. It can be an acquired or congenital with an autosomal dominant inheritance. The histopathological features are not well described in the ophthalmic literature, however they include abnormal pilosebaceous units within the posterior lamella of the eyelid and perifollicular chronic inflammatory cell infiltration. In this report, we describe the histopathological findings of three congenital distichiasis cases treated at King Khaled Eye Specialist Hospital (KKESH), Riyadh, Saudi Arabia with discussion on the pathogenesis of such a condition and the differentiating features from ectopic cilia.</p>
</div>
</front>
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<pmc article-type="brief-report">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Saudi J Ophthalmol</journal-id>
<journal-id journal-id-type="iso-abbrev">Saudi J Ophthalmol</journal-id>
<journal-title-group>
<journal-title>Saudi Journal of Ophthalmology</journal-title>
</journal-title-group>
<issn pub-type="ppub">1319-4534</issn>
<publisher>
<publisher-name>Elsevier</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">28860915</article-id>
<article-id pub-id-type="pmc">5569325</article-id>
<article-id pub-id-type="publisher-id">S1319-4534(17)30072-3</article-id>
<article-id pub-id-type="doi">10.1016/j.sjopt.2017.05.003</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Case Report</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Congenital distichiasis: Histopathological report of 3 cases
<sup>
<xref ref-type="fn" rid="d31e29"></xref>
</sup>
</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Alkatan</surname>
<given-names>Hind Manaa</given-names>
</name>
<email>hindkatan@yahoo.com</email>
<email>hkatan@ksu.edu.sa</email>
<xref rid="af005" ref-type="aff">a</xref>
<xref rid="cor1" ref-type="corresp"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Galindo-Ferreiro</surname>
<given-names>Alicia</given-names>
</name>
<xref rid="af010" ref-type="aff">b</xref>
<xref rid="af015" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Maktabi</surname>
<given-names>Azza</given-names>
</name>
<xref rid="af010" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Galvez-Ruiz</surname>
<given-names>Alberto</given-names>
</name>
<xref rid="af010" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Schellini</surname>
<given-names>Silvana</given-names>
</name>
<xref rid="af010" ref-type="aff">b</xref>
<xref rid="af020" ref-type="aff">d</xref>
</contrib>
</contrib-group>
<aff id="af005">
<label>a</label>
Departments of Ophthalmology & Pathology, King Saud University College of Medicine, Riyadh, Saudi Arabia</aff>
<aff id="af010">
<label>b</label>
Department of Pathology and Oculoplastic Division, King Khaled Eye Specialist Hospital, Saudi Arabia</aff>
<aff id="af015">
<label>c</label>
Department of Ophthalmology, Rio Hortega University Hospital, Valladolid, Spain</aff>
<aff id="af020">
<label>d</label>
Department of Ophthalmology, Faculdade de Medicina de Botucatu - UNESP, São Paulo, Brazil</aff>
<author-notes>
<corresp id="cor1">
<label></label>
Corresponding author at: Departments of Ophthalmology & Pathology, King Saud University Medical City, PO Box 18097, Riyadh 11415, Saudi Arabia.Departments of Ophthalmology & PathologyKing Saud University Medical CityPO Box 18097Riyadh11415Saudi Arabia
<email>hindkatan@yahoo.com</email>
<email>hkatan@ksu.edu.sa</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release">
<day>18</day>
<month>5</month>
<year>2017</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub">
<season>Jul-Sep</season>
<year>2017</year>
</pub-date>
<pub-date pub-type="epub">
<day>18</day>
<month>5</month>
<year>2017</year>
</pub-date>
<volume>31</volume>
<issue>3</issue>
<fpage>165</fpage>
<lpage>168</lpage>
<history>
<date date-type="received">
<day>27</day>
<month>10</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>9</day>
<month>5</month>
<year>2017</year>
</date>
</history>
<permissions>
<copyright-statement>© 2017 The Authors</copyright-statement>
<copyright-year>2017</copyright-year>
<license license-type="CC BY-NC-ND" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/">
<license-p>This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).</license-p>
</license>
</permissions>
<abstract id="ab005">
<p>Distichiasis is a condition clinically presenting as partial or complete accessory row of lashes that emerges from the meibomian glands orifices. It can be an acquired or congenital with an autosomal dominant inheritance. The histopathological features are not well described in the ophthalmic literature, however they include abnormal pilosebaceous units within the posterior lamella of the eyelid and perifollicular chronic inflammatory cell infiltration. In this report, we describe the histopathological findings of three congenital distichiasis cases treated at King Khaled Eye Specialist Hospital (KKESH), Riyadh, Saudi Arabia with discussion on the pathogenesis of such a condition and the differentiating features from ectopic cilia.</p>
</abstract>
<kwd-group id="kg005">
<title>Keywords</title>
<kwd>Congenital</kwd>
<kwd>Eyelid</kwd>
<kwd>Distichiasis</kwd>
<kwd>Cilia</kwd>
<kwd>Histopathology</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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