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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comorbidities of hidradenitis suppurativa (acne inversa)</title>
<author><name sortKey="Fimmel, Sabine" sort="Fimmel, Sabine" uniqKey="Fimmel S" first="Sabine" last="Fimmel">Sabine Fimmel</name>
<affiliation><nlm:aff id="A1">Laboratory for Biogerontology; Dermato-Pharmacology and Dermato-Endocrinology; Institute of Clinical Pharmacology and Toxicology; Campus Benjamin Franklin; Charité Universitaetsmedizin Berlin, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zouboulis, Christos C" sort="Zouboulis, Christos C" uniqKey="Zouboulis C" first="Christos C" last="Zouboulis">Christos C. Zouboulis</name>
<affiliation><nlm:aff id="A1">Laboratory for Biogerontology; Dermato-Pharmacology and Dermato-Endocrinology; Institute of Clinical Pharmacology and Toxicology; Campus Benjamin Franklin; Charité Universitaetsmedizin Berlin, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A2">Departments of Dermatology, Venereology, Allergology and Immunology; Dessau Medical Center; Dessau, Germany</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21547142</idno>
<idno type="pmc">3084959</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084959</idno>
<idno type="RBID">PMC:3084959</idno>
<idno type="doi">10.4161/derm.2.1.12490</idno>
<date when="2010">2010</date>
<idno type="wicri:Area/Pmc/Corpus">001E64</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E64</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Comorbidities of hidradenitis suppurativa (acne inversa)</title>
<author><name sortKey="Fimmel, Sabine" sort="Fimmel, Sabine" uniqKey="Fimmel S" first="Sabine" last="Fimmel">Sabine Fimmel</name>
<affiliation><nlm:aff id="A1">Laboratory for Biogerontology; Dermato-Pharmacology and Dermato-Endocrinology; Institute of Clinical Pharmacology and Toxicology; Campus Benjamin Franklin; Charité Universitaetsmedizin Berlin, Germany</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Zouboulis, Christos C" sort="Zouboulis, Christos C" uniqKey="Zouboulis C" first="Christos C" last="Zouboulis">Christos C. Zouboulis</name>
<affiliation><nlm:aff id="A1">Laboratory for Biogerontology; Dermato-Pharmacology and Dermato-Endocrinology; Institute of Clinical Pharmacology and Toxicology; Campus Benjamin Franklin; Charité Universitaetsmedizin Berlin, Germany</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A2">Departments of Dermatology, Venereology, Allergology and Immunology; Dessau Medical Center; Dessau, Germany</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Dermato-endocrinology</title>
<idno type="ISSN">1938-1972</idno>
<idno type="eISSN">1938-1980</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
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<front><div type="abstract" xml:lang="en"><p>Comorbidities of hidradenitis suppurativa (acne inversa) were reviewed by extracting original and review publications included in MEDLINE, EMBASE and COCHRANE libraries using the terms “hidradenitis,” “Verneuil” and “acne inversa.” Follicular occlusion disorders, inflammatory bowel diseases, especially Crohn disease, spondylarthropathy, other hyperergic diseases, genetic keratin disorders associated with follicular occlusion and squamous cell carcinoma were the most common hidradenitis suppurativa comorbid diseases. A first classification of these major comorbidities and their possible genetic background reveals a list of chromosome loci and genes, which could be hidradenitis suppurativa candidates. Most of these diseases belong to the group of autoinflammatory disorders, where th17 cell cytokines seem to play a central role.</p>
</div>
</front>
</TEI>
<pmc article-type="brief-report"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Dermatoendocrinol</journal-id>
<journal-id journal-id-type="publisher-id">DE</journal-id>
<journal-title-group><journal-title>Dermato-endocrinology</journal-title>
</journal-title-group>
<issn pub-type="ppub">1938-1972</issn>
<issn pub-type="epub">1938-1980</issn>
<publisher><publisher-name>Landes Bioscience</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">21547142</article-id>
<article-id pub-id-type="pmc">3084959</article-id>
<article-id pub-id-type="publisher-id">1938-1972-2-1-3</article-id>
<article-id pub-id-type="doi">10.4161/derm.2.1.12490</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Report</subject>
</subj-group>
</article-categories>
<title-group><article-title>Comorbidities of hidradenitis suppurativa (acne inversa)</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Fimmel</surname>
<given-names>Sabine</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Zouboulis</surname>
<given-names>Christos C</given-names>
</name>
<xref ref-type="aff" rid="A1">1</xref>
<xref ref-type="aff" rid="A2">2</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
Laboratory for Biogerontology; Dermato-Pharmacology and Dermato-Endocrinology; Institute of Clinical Pharmacology and Toxicology; Campus Benjamin Franklin; Charité Universitaetsmedizin Berlin, Germany</aff>
<aff id="A2"><label>2</label>
Departments of Dermatology, Venereology, Allergology and Immunology; Dessau Medical Center; Dessau, Germany</aff>
<author-notes><corresp>Correspondence to: Christos C. Zouboulis; Email: <email>christos.zouboulis@klinikum-dessau.de</email>
</corresp>
</author-notes>
<pub-date pub-type="ppub"><season>Jan-Mar</season>
<year>2010</year>
</pub-date>
<volume>2</volume>
<issue>1</issue>
<fpage>9</fpage>
<lpage>16</lpage>
<history><date date-type="received"><day>21</day>
<month>5</month>
<year>2010</year>
</date>
<date date-type="accepted"><day>25</day>
<month>5</month>
<year>2010</year>
</date>
</history>
<permissions><copyright-statement>Copyright © 2010 Landes Bioscience</copyright-statement>
<copyright-year>2010</copyright-year>
</permissions>
<abstract><p>Comorbidities of hidradenitis suppurativa (acne inversa) were reviewed by extracting original and review publications included in MEDLINE, EMBASE and COCHRANE libraries using the terms “hidradenitis,” “Verneuil” and “acne inversa.” Follicular occlusion disorders, inflammatory bowel diseases, especially Crohn disease, spondylarthropathy, other hyperergic diseases, genetic keratin disorders associated with follicular occlusion and squamous cell carcinoma were the most common hidradenitis suppurativa comorbid diseases. A first classification of these major comorbidities and their possible genetic background reveals a list of chromosome loci and genes, which could be hidradenitis suppurativa candidates. Most of these diseases belong to the group of autoinflammatory disorders, where th17 cell cytokines seem to play a central role.</p>
</abstract>
<kwd-group><title>Key words</title>
<kwd>hidradentitis suppurativa</kwd>
<kwd>acne inversa</kwd>
<kwd>autoimmune diseases</kwd>
<kwd>Crohn disease</kwd>
<kwd>spondylarthropathy</kwd>
<kwd>follicular occlusion</kwd>
<kwd>autoinflammatory disorders</kwd>
<kwd>Th17 cell cytokines</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>
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