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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">PS1-8: A Prospective Study of Breast Cancer Survivorship in Kaiser Permanente Northern California: The Pathways Study</title><author><name sortKey="Roh, Janise" sort="Roh, Janise" uniqKey="Roh J" first="Janise" last="Roh">Janise Roh</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Munneke, Julie" sort="Munneke, Julie" uniqKey="Munneke J" first="Julie" last="Munneke">Julie Munneke</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Kwan, Marilyn" sort="Kwan, Marilyn" uniqKey="Kwan M" first="Marilyn" last="Kwan">Marilyn Kwan</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Ergas, Isaac" sort="Ergas, Isaac" uniqKey="Ergas I" first="Isaac" last="Ergas">Isaac Ergas</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Song, Jun" sort="Song, Jun" uniqKey="Song J" first="Jun" last="Song">Jun Song</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Yao, Song" sort="Yao, Song" uniqKey="Yao S" first="Song" last="Yao">Song Yao</name><affiliation><nlm:aff id="af2-0110126a">Roswell Park Cancer Institute</nlm:aff></affiliation></author><author><name sortKey="Ambrosone, Christine" sort="Ambrosone, Christine" uniqKey="Ambrosone C" first="Christine" last="Ambrosone">Christine Ambrosone</name><affiliation><nlm:aff id="af2-0110126a">Roswell Park Cancer Institute</nlm:aff></affiliation></author><author><name sortKey="Wiencke, John" sort="Wiencke, John" uniqKey="Wiencke J" first="John" last="Wiencke">John Wiencke</name><affiliation><nlm:aff id="af3-0110126a">UCSF Helen Diller Family Comprehensive Cancer Center</nlm:aff></affiliation></author><author><name sortKey="Lee, Marion" sort="Lee, Marion" uniqKey="Lee M" first="Marion" last="Lee">Marion Lee</name><affiliation><nlm:aff id="af4-0110126a">University of California, San Francisco</nlm:aff></affiliation></author><author><name sortKey="Gomez, Scarlett" sort="Gomez, Scarlett" uniqKey="Gomez S" first="Scarlett" last="Gomez">Scarlett Gomez</name><affiliation><nlm:aff id="af5-0110126a">Cancer Prevention Institute of California</nlm:aff></affiliation></author><author><name sortKey="Barlow, Janice" sort="Barlow, Janice" uniqKey="Barlow J" first="Janice" last="Barlow">Janice Barlow</name><affiliation><nlm:aff id="af6-0110126a">Zero Breast Cancer</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">3788404</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788404</idno><idno type="RBID">PMC:3788404</idno><idno type="doi">10.3121/cmr.2013.1176.ps1-8</idno><idno type="pmid">NONE</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001D57</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D57</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">PS1-8: A Prospective Study of Breast Cancer Survivorship in Kaiser Permanente Northern California: The Pathways Study</title><author><name sortKey="Roh, Janise" sort="Roh, Janise" uniqKey="Roh J" first="Janise" last="Roh">Janise Roh</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Munneke, Julie" sort="Munneke, Julie" uniqKey="Munneke J" first="Julie" last="Munneke">Julie Munneke</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Kwan, Marilyn" sort="Kwan, Marilyn" uniqKey="Kwan M" first="Marilyn" last="Kwan">Marilyn Kwan</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Ergas, Isaac" sort="Ergas, Isaac" uniqKey="Ergas I" first="Isaac" last="Ergas">Isaac Ergas</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Song, Jun" sort="Song, Jun" uniqKey="Song J" first="Jun" last="Song">Jun Song</name><affiliation><nlm:aff id="af1-0110126a">Kaiser Permanente Northern Californa</nlm:aff></affiliation></author><author><name sortKey="Yao, Song" sort="Yao, Song" uniqKey="Yao S" first="Song" last="Yao">Song Yao</name><affiliation><nlm:aff id="af2-0110126a">Roswell Park Cancer Institute</nlm:aff></affiliation></author><author><name sortKey="Ambrosone, Christine" sort="Ambrosone, Christine" uniqKey="Ambrosone C" first="Christine" last="Ambrosone">Christine Ambrosone</name><affiliation><nlm:aff id="af2-0110126a">Roswell Park Cancer Institute</nlm:aff></affiliation></author><author><name sortKey="Wiencke, John" sort="Wiencke, John" uniqKey="Wiencke J" first="John" last="Wiencke">John Wiencke</name><affiliation><nlm:aff id="af3-0110126a">UCSF Helen Diller Family Comprehensive Cancer Center</nlm:aff></affiliation></author><author><name sortKey="Lee, Marion" sort="Lee, Marion" uniqKey="Lee M" first="Marion" last="Lee">Marion Lee</name><affiliation><nlm:aff id="af4-0110126a">University of California, San Francisco</nlm:aff></affiliation></author><author><name sortKey="Gomez, Scarlett" sort="Gomez, Scarlett" uniqKey="Gomez S" first="Scarlett" last="Gomez">Scarlett Gomez</name><affiliation><nlm:aff id="af5-0110126a">Cancer Prevention Institute of California</nlm:aff></affiliation></author><author><name sortKey="Barlow, Janice" sort="Barlow, Janice" uniqKey="Barlow J" first="Janice" last="Barlow">Janice Barlow</name><affiliation><nlm:aff id="af6-0110126a">Zero Breast Cancer</nlm:aff></affiliation></author></analytic><series><title level="j">Clinical Medicine & Research</title><idno type="ISSN">1539-4182</idno><idno type="eISSN">1554-6179</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background/Aims</title><p>With over 2.5 million breast cancer survivors in the U.S. today, identification of modifiable factors associated with recurrence and survival is imperative. The Pathways Study, a prospective study of breast cancer survivors in Kaiser Permanente Northern California (KPNC) is examining the effects of lifestyle (e.g., diet, physical activity, complementary and alternative medicine [CAM]), contextual (e.g., social and built environment characteristics), medical care, and genetic and molecular factors on breast cancer prognosis.</p></sec><sec><title>Methods</title><p>Women who are newly-diagnosed with invasive breast cancer are identified daily from KPNC electronic pathology records. Eligibility criteria include being at least 21 years old at diagnosis, no previous history of invasive cancer, and English, Spanish, or Chinese-speaking. Women are enrolled during an in-person baseline interview with collection of blood and saliva specimens, and followed periodically for lifestyle updates, treatment, and outcomes via mailed questionnaires, telephone interviews, and web surveys. Outcomes are also confirmed using KPNC electronic databases.</p></sec><sec><title>Results</title><p>As of October 23, 2012, 4,340 women have been enrolled. The cohort is racially and ethnically diverse: 62% White, 12% Hispanic, 12% Asian, 8% Black, 3% Other. Blood and saliva have been obtained on 89% and 95% of enrollees, respectively. Recruitment is planned to end in March 2013, and follow-up will continue through June 2015 and beyond pending further funding. A total of 230 recurrences and 245 deaths have been confirmed.</p></sec><sec><title>Conclusions</title><p>To date, 14 papers have been published on topics ranging from CAM use at diagnosis, quality of life at diagnosis, lymphedema risk factors, physical activity during treatment, employment status and quality of life, adherence to adjuvant hormonal therapy, breast cancer DNA methylation profiles, and correlates of breast cancer subtypes. The Pathways Study has provided a platform for several ancillary studies, investigating lymphedema, racial disparities in treatment, the physiology of aging, and bone health, and also has provided support for several career development awards. The research team has also included Zero Breast Cancer, a nonprofit organization dedicated to breast cancer research through community participation. The Pathways Study has become a rich resource of behavioral, genetic and molecular factors and breast cancer outcomes.</p></sec></div></front></TEI><pmc article-type="abstract"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Med Res</journal-id><journal-id journal-id-type="iso-abbrev">Clin Med Res</journal-id><journal-id journal-id-type="hwp">clinmedres</journal-id><journal-title-group><journal-title>Clinical Medicine & Research</journal-title></journal-title-group><issn pub-type="ppub">1539-4182</issn><issn pub-type="epub">1554-6179</issn><publisher><publisher-name>Marshfield Clinic</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">3788404</article-id><article-id pub-id-type="doi">10.3121/cmr.2013.1176.ps1-8</article-id><article-id pub-id-type="publisher-id">0110126a</article-id><article-categories><subj-group subj-group-type="heading"><subject>Selected Abstracts-HMORN 2013: Cancer</subject></subj-group></article-categories><title-group><article-title>PS1-8: A Prospective Study of Breast Cancer Survivorship in Kaiser Permanente Northern California: The Pathways Study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Roh</surname><given-names>Janise</given-names></name><xref ref-type="aff" rid="af1-0110126a">1</xref></contrib><contrib contrib-type="author"><name><surname>Munneke</surname><given-names>Julie</given-names></name><xref ref-type="aff" rid="af1-0110126a">1</xref></contrib><contrib contrib-type="author"><name><surname>Kwan</surname><given-names>Marilyn</given-names></name><xref ref-type="aff" rid="af1-0110126a">1</xref></contrib><contrib contrib-type="author"><name><surname>Ergas</surname><given-names>Isaac</given-names></name><xref ref-type="aff" rid="af1-0110126a">1</xref></contrib><contrib contrib-type="author"><name><surname>Song</surname><given-names>Jun</given-names></name><xref ref-type="aff" rid="af1-0110126a">1</xref></contrib><contrib contrib-type="author"><name><surname>Yao</surname><given-names>Song</given-names></name><xref ref-type="aff" rid="af2-0110126a">2</xref></contrib><contrib contrib-type="author"><name><surname>Ambrosone</surname><given-names>Christine</given-names></name><xref ref-type="aff" rid="af2-0110126a">2</xref></contrib><contrib contrib-type="author"><name><surname>Wiencke</surname><given-names>John</given-names></name><xref ref-type="aff" rid="af3-0110126a">3</xref></contrib><contrib contrib-type="author"><name><surname>Lee</surname><given-names>Marion</given-names></name><xref ref-type="aff" rid="af4-0110126a">4</xref></contrib><contrib contrib-type="author"><name><surname>Gomez</surname><given-names>Scarlett</given-names></name><xref ref-type="aff" rid="af5-0110126a">5</xref></contrib><contrib contrib-type="author"><name><surname>Barlow</surname><given-names>Janice</given-names></name><xref ref-type="aff" rid="af6-0110126a">6</xref></contrib></contrib-group><aff id="af1-0110126a"><label>1</label>Kaiser Permanente Northern Californa</aff><aff id="af2-0110126a"><label>2</label>Roswell Park Cancer Institute</aff><aff id="af3-0110126a"><label>3</label>UCSF Helen Diller Family Comprehensive Cancer Center</aff><aff id="af4-0110126a"><label>4</label>University of California, San Francisco</aff><aff id="af5-0110126a"><label>5</label>Cancer Prevention Institute of California</aff><aff id="af6-0110126a"><label>6</label>Zero Breast Cancer</aff><pub-date pub-type="ppub"><month>9</month><year>2013</year></pub-date><volume>11</volume><issue>3</issue><fpage seq="b">126</fpage><lpage>126</lpage><permissions><copyright-statement>© 2013 Marshfield Clinic</copyright-statement><copyright-year>2013</copyright-year></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="126a.pdf"></self-uri><abstract><sec><title>Background/Aims</title><p>With over 2.5 million breast cancer survivors in the U.S. today, identification of modifiable factors associated with recurrence and survival is imperative. The Pathways Study, a prospective study of breast cancer survivors in Kaiser Permanente Northern California (KPNC) is examining the effects of lifestyle (e.g., diet, physical activity, complementary and alternative medicine [CAM]), contextual (e.g., social and built environment characteristics), medical care, and genetic and molecular factors on breast cancer prognosis.</p></sec><sec><title>Methods</title><p>Women who are newly-diagnosed with invasive breast cancer are identified daily from KPNC electronic pathology records. Eligibility criteria include being at least 21 years old at diagnosis, no previous history of invasive cancer, and English, Spanish, or Chinese-speaking. Women are enrolled during an in-person baseline interview with collection of blood and saliva specimens, and followed periodically for lifestyle updates, treatment, and outcomes via mailed questionnaires, telephone interviews, and web surveys. Outcomes are also confirmed using KPNC electronic databases.</p></sec><sec><title>Results</title><p>As of October 23, 2012, 4,340 women have been enrolled. The cohort is racially and ethnically diverse: 62% White, 12% Hispanic, 12% Asian, 8% Black, 3% Other. Blood and saliva have been obtained on 89% and 95% of enrollees, respectively. Recruitment is planned to end in March 2013, and follow-up will continue through June 2015 and beyond pending further funding. A total of 230 recurrences and 245 deaths have been confirmed.</p></sec><sec><title>Conclusions</title><p>To date, 14 papers have been published on topics ranging from CAM use at diagnosis, quality of life at diagnosis, lymphedema risk factors, physical activity during treatment, employment status and quality of life, adherence to adjuvant hormonal therapy, breast cancer DNA methylation profiles, and correlates of breast cancer subtypes. The Pathways Study has provided a platform for several ancillary studies, investigating lymphedema, racial disparities in treatment, the physiology of aging, and bone health, and also has provided support for several career development awards. The research team has also included Zero Breast Cancer, a nonprofit organization dedicated to breast cancer research through community participation. The Pathways Study has become a rich resource of behavioral, genetic and molecular factors and breast cancer outcomes.</p></sec></abstract><kwd-group><kwd>Breast Cancer</kwd><kwd>Survivorship</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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