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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">PB.04: MRI In lobular and mixed lobular/ductal carcinomas: can we preselect cases based on imaging appearance?</title><author><name sortKey="Hoosein, Mm" sort="Hoosein, Mm" uniqKey="Hoosein M" first="Mm" last="Hoosein">Mm Hoosein</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Grosvenor, L" sort="Grosvenor, L" uniqKey="Grosvenor L" first="L" last="Grosvenor">L. Grosvenor</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Lister, D" sort="Lister, D" uniqKey="Lister D" first="D" last="Lister">D. Lister</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Al Attar, M" sort="Al Attar, M" uniqKey="Al Attar M" first="M" last="Al-Attar">M. Al-Attar</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">3980898</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980898</idno><idno type="RBID">PMC:3980898</idno><idno type="doi">10.1186/bcr3506</idno><idno type="pmid">NONE</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001D47</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D47</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">PB.04: MRI In lobular and mixed lobular/ductal carcinomas: can we preselect cases based on imaging appearance?</title><author><name sortKey="Hoosein, Mm" sort="Hoosein, Mm" uniqKey="Hoosein M" first="Mm" last="Hoosein">Mm Hoosein</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Grosvenor, L" sort="Grosvenor, L" uniqKey="Grosvenor L" first="L" last="Grosvenor">L. Grosvenor</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Lister, D" sort="Lister, D" uniqKey="Lister D" first="D" last="Lister">D. Lister</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author><author><name sortKey="Al Attar, M" sort="Al Attar, M" uniqKey="Al Attar M" first="M" last="Al-Attar">M. Al-Attar</name><affiliation><nlm:aff id="I1">University Hospitals of Leicester, UK</nlm:aff></affiliation></author></analytic><series><title level="j">Breast Cancer Research : BCR</title><idno type="ISSN">1465-5411</idno><idno type="eISSN">1465-542X</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader></TEI><pmc article-type="abstract" xml:lang="en"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Breast Cancer Res</journal-id><journal-id journal-id-type="iso-abbrev">Breast Cancer Res</journal-id><journal-title-group><journal-title>Breast Cancer Research : BCR</journal-title></journal-title-group><issn pub-type="ppub">1465-5411</issn><issn pub-type="epub">1465-542X</issn><publisher><publisher-name>BioMed Central</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">3980898</article-id><article-id pub-id-type="publisher-id">bcr3506</article-id><article-id pub-id-type="doi">10.1186/bcr3506</article-id><article-categories><subj-group subj-group-type="heading"><subject>Poster Presentation</subject></subj-group></article-categories><title-group><article-title>PB.04: MRI In lobular and mixed lobular/ductal carcinomas: can we preselect cases based on imaging appearance?</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes" id="A1"><name><surname>Hoosein</surname><given-names>MM</given-names></name><xref ref-type="aff" rid="I1">1</xref></contrib><contrib contrib-type="author" id="A2"><name><surname>Grosvenor</surname><given-names>L</given-names></name><xref ref-type="aff" rid="I1">1</xref></contrib><contrib contrib-type="author" id="A3"><name><surname>Lister</surname><given-names>D</given-names></name><xref ref-type="aff" rid="I1">1</xref></contrib><contrib contrib-type="author" id="A4"><name><surname>Al-Attar</surname><given-names>M</given-names></name><xref ref-type="aff" rid="I1">1</xref></contrib></contrib-group><aff id="I1"><label>1</label>University Hospitals of Leicester, UK</aff><pub-date pub-type="ppub"><year>2013</year></pub-date><pub-date pub-type="epub"><day>8</day><month>11</month><year>2013</year></pub-date><volume>15</volume><issue>Suppl 1</issue><supplement><named-content content-type="supplement-title">British Society of Breast Radiology Annual Scientific Meeting 2013</named-content><named-content content-type="supplement-sponsor">Publication of this supplement has been supported by the British Society of Breast Radiology.</named-content></supplement><fpage>P4</fpage><lpage>P4</lpage><permissions><copyright-statement>Copyright © 2013 Hoosein et al.; licensee BioMed Central Ltd.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder>Hoosein et al.; licensee BioMed Central Ltd.</copyright-holder><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0"><license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/2.0">http://creativecommons.org/licenses/by/2.0</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/publicdomain/zero/1.0/">http://creativecommons.org/publicdomain/zero/1.0/</ext-link>) applies to the data made available in this article, unless otherwise stated.</license-p></license></permissions><self-uri xlink:href="http://breast-cancer-research.com/content/15/S1/P4"></self-uri><conference><conf-date>10-12 November 2013</conf-date><conf-name>British Society of Breast Radiology Annual Scientific Meeting 2013</conf-name><conf-loc>Liverpool, UK</conf-loc></conference></article-meta></front><body><sec sec-type="intro"><title>Introduction</title><p>Lobular carcinoma presents a diagnostic challenge. Imaging and clinical findings are usually subtle. In the current climate it imposes extra strain on our resources. Our aim was to assess contribution of MRI in the preoperative local staging of lobular and mixed lobular/ductal carcinoma and to evaluate whether we can select cases for preoperative MRI based on mammographic appearance.</p></sec><sec sec-type="methods"><title>Methods</title><p>A retrospective review of data provided by the local breast cancer database was performed. Patients with confirmed lobular or mixed lobular/ductal carcinomas that had MRI staging during a 5-year period were identified. Imaging and histopathology reports were reviewed. A total of 381 cancers were diagnosed in the study period. Ninety-one patients had breast MRI. Four cases were excluded as no final histology was available. Eighty-seven patients (mean age 58) with 89 involved breasts constituted our study population.</p></sec><sec sec-type="results"><title>Results</title><p>Breakdown of mammographic lesions was as follows: PD, 39 (43.8%); masses, 20 (22.4%); ASD, 18 (20.2%); lymphoedema, one (1.1%); calcifications, two (2.2%); occult/subtle, nine (10.1%). MRI had a positive contribution in 27/83 cases (32.5%), did not add any further information in 49/83 cases (59%) and a negative contribution in only 7/83 cases (8.4%). MRI notably identified greater disease extent, multifocal and contralateral disease. MRI was most useful in assessing disease extent when lobular carcinoma presented as PD or mammographically occult and was of least benefit when presenting as a mass lesion.</p></sec><sec sec-type="conclusions"><title>Conclusion</title><p>MRI had no advantage over conventional imaging in the majority of lobular and mixed lobular/ductal cancers presenting as a focal mass lesion. Its application could be tailored more specifically to assess nonmass lesions.</p></sec></body></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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