Breast cancer in the elderly.
Identifieur interne : 001C80 ( Pmc/Corpus ); précédent : 001C79; suivant : 001C81Breast cancer in the elderly.
Auteurs : M. Bellet ; C. Alonso ; B. OjedaSource :
- Postgraduate Medical Journal [ 0032-5473 ] ; 1995.
Abstract
Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric population is scarce; secondly, the number of patients is increasing, and thirdly there are conflicting data regarding the actual effectiveness of the different treatments. The present review attempts to outline the specific characteristics of this malignancy in the elderly in terms of histological pattern, stage at diagnosis, and outcome. The feasibility of standard therapies (mastectomy/lumpectomy, axillary clearance, and radio-therapy) in the elderly is carefully analysed, and compared to the efficacy of less aggressive procedures. The use of tamoxifen as a primary treatment, instead of surgery, is critically reconsidered, as well as its use as an adjuvant therapy. Finally, the effectiveness of systemic therapy in advanced disease is also discussed.
Url:
PubMed: 7494769
PubMed Central: 2398357
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PMC:2398357Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Breast cancer in the elderly.</title><author><name sortKey="Bellet, M" sort="Bellet, M" uniqKey="Bellet M" first="M." last="Bellet">M. Bellet</name></author><author><name sortKey="Alonso, C" sort="Alonso, C" uniqKey="Alonso C" first="C." last="Alonso">C. Alonso</name></author><author><name sortKey="Ojeda, B" sort="Ojeda, B" uniqKey="Ojeda B" first="B." last="Ojeda">B. Ojeda</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">7494769</idno><idno type="pmc">2398357</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2398357</idno><idno type="RBID">PMC:2398357</idno><date when="1995">1995</date><idno type="wicri:Area/Pmc/Corpus">001C80</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001C80</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Breast cancer in the elderly.</title><author><name sortKey="Bellet, M" sort="Bellet, M" uniqKey="Bellet M" first="M." last="Bellet">M. Bellet</name></author><author><name sortKey="Alonso, C" sort="Alonso, C" uniqKey="Alonso C" first="C." last="Alonso">C. Alonso</name></author><author><name sortKey="Ojeda, B" sort="Ojeda, B" uniqKey="Ojeda B" first="B." last="Ojeda">B. Ojeda</name></author></analytic><series><title level="j">Postgraduate Medical Journal</title><idno type="ISSN">0032-5473</idno><idno type="eISSN">1469-0756</idno><imprint><date when="1995">1995</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric population is scarce; secondly, the number of patients is increasing, and thirdly there are conflicting data regarding the actual effectiveness of the different treatments. The present review attempts to outline the specific characteristics of this malignancy in the elderly in terms of histological pattern, stage at diagnosis, and outcome. The feasibility of standard therapies (mastectomy/lumpectomy, axillary clearance, and radio-therapy) in the elderly is carefully analysed, and compared to the efficacy of less aggressive procedures. The use of tamoxifen as a primary treatment, instead of surgery, is critically reconsidered, as well as its use as an adjuvant therapy. Finally, the effectiveness of systemic therapy in advanced disease is also discussed.</p><sec sec-type="scanned-figures"><title>Images</title><fig id="F1"><label>Figure</label><graphic xlink:href="postmedj00035-0021-a" xlink:role="659"></graphic></fig></sec></div></front></TEI><pmc article-type="review-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Postgrad Med J</journal-id><journal-id journal-id-type="pmc">postmedj</journal-id><journal-title>Postgraduate Medical Journal</journal-title><issn pub-type="ppub">0032-5473</issn><issn pub-type="epub">1469-0756</issn><publisher><publisher-name>BMJ Group</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">7494769</article-id><article-id pub-id-type="pmc">2398357</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Breast cancer in the elderly.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Bellet</surname><given-names>M.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Alonso</surname><given-names>C.</given-names></name></contrib><contrib contrib-type="author"><name><surname>Ojeda</surname><given-names>B.</given-names></name></contrib></contrib-group><aff>Department of Medical Oncology, Hospital Sta Creu i Sant Pau, Barcelona, Spain.</aff><pub-date pub-type="ppub"><month>11</month><year>1995</year></pub-date><volume>71</volume><issue>841</issue><fpage>658</fpage><lpage>664</lpage><abstract><p>Breast cancer in the elderly has attracted considerable interest in recent years for three main reasons. Firstly, information concerning the profile (clinical and biological) of the disease in the geriatric population is scarce; secondly, the number of patients is increasing, and thirdly there are conflicting data regarding the actual effectiveness of the different treatments. The present review attempts to outline the specific characteristics of this malignancy in the elderly in terms of histological pattern, stage at diagnosis, and outcome. The feasibility of standard therapies (mastectomy/lumpectomy, axillary clearance, and radio-therapy) in the elderly is carefully analysed, and compared to the efficacy of less aggressive procedures. The use of tamoxifen as a primary treatment, instead of surgery, is critically reconsidered, as well as its use as an adjuvant therapy. Finally, the effectiveness of systemic therapy in advanced disease is also discussed.</p><sec sec-type="scanned-figures"><title>Images</title><fig id="F1"><label>Figure</label><graphic xlink:href="postmedj00035-0021-a" xlink:role="659"></graphic></fig></sec></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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