Epidermoid Cancers of the Anal Canal: Current Treatment
Identifieur interne : 001C63 ( Pmc/Corpus ); précédent : 001C62; suivant : 001C64Epidermoid Cancers of the Anal Canal: Current Treatment
Auteurs : Jennifer Blumetti ; Amir L. BastawrousSource :
- Clinics in Colon and Rectal Surgery [ 1531-0043 ] ; 2009.
Abstract
Epidermoid carcinoma of the anal canal is an uncommon disease, but has increased in incidence with the HIV epidemic. Prior to the 1970s, treatment consisted of radical surgery with abdominoperineal resection. With the pioneering work of Dr. Norman Nigro, this has shifted to a nonsurgical approach, with primary treatment consisting of multimodality therapy with radiation and chemotherapy. This review provides an overview of the historical, current, and future treatments of epidermoid anal canal malignancies.
Url:
DOI: 10.1055/s-0029-1223838
PubMed: 20436831
PubMed Central: 2780240
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PMC:2780240Le document en format XML
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Colon Rectal Surg</journal-id><journal-title>Clinics in Colon and Rectal Surgery</journal-title><issn pub-type="ppub">1531-0043</issn><issn pub-type="epub">1530-9681</issn><publisher><publisher-name>Thieme Medical Publishers</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">20436831</article-id><article-id pub-id-type="pmc">2780240</article-id><article-id pub-id-type="doi">10.1055/s-0029-1223838</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Epidermoid Cancers of the Anal Canal: Current Treatment</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Blumetti</surname><given-names>Jennifer</given-names></name><xref rid="a22077-1" ref-type="aff">1</xref><degrees>M.D.</degrees></contrib><contrib contrib-type="author"><name><surname>Bastawrous</surname><given-names>Amir L.</given-names></name><xref rid="a22077-1" ref-type="aff">1</xref><xref rid="a22077-2" ref-type="aff">2</xref><degrees>M.D.</degrees></contrib></contrib-group><aff id="a22077-1"><label>1</label>Division of Colon and Rectal Surgery, Department of Surgery, University of Illinois at Chicago, Chicago, Illinois</aff><aff id="a22077-2"><label>2</label>Stroger Hospital of Cook County, Chicago, Illinois</aff><author-notes><corresp>Address for correspondence and reprint requests: Amir L. Bastawrous M.D. <institution>Stroger Hospital of Cook County, Cook County Admin. Bldg.</institution> <addr-line>1900 W. Polk St., #401, Chicago, IL 60612-3736</addr-line> <email>bastawro@uic.edu</email></corresp></author-notes><pub-date pub-type="ppub"><month>5</month><year>2009</year></pub-date><volume>22</volume><issue>2</issue><fpage>77</fpage><lpage>83</lpage><copyright-statement>© Thieme Medical Publishers</copyright-statement><abstract xml:lang="en"><title>ABSTRACT</title><p>Epidermoid carcinoma of the anal canal is an uncommon disease, but has increased in incidence with the HIV epidemic. Prior to the 1970s, treatment consisted of radical surgery with abdominoperineal resection. With the pioneering work of Dr. Norman Nigro, this has shifted to a nonsurgical approach, with primary treatment consisting of multimodality therapy with radiation and chemotherapy. This review provides an overview of the historical, current, and future treatments of epidermoid anal canal malignancies.</p></abstract><kwd-group xml:lang="en"><kwd>Anal canal malignancy</kwd><kwd>epidermoid carcinoma</kwd><kwd>chemoradiation</kwd><kwd>Nigro protocol</kwd></kwd-group><custom-meta-wrap><custom-meta><meta-name>issue-theme</meta-name><meta-value>Anal Cancer and Retrorectal Tumors</meta-value></custom-meta><custom-meta><meta-name>issue-editor</meta-name><meta-value>Guest Editor
Jan Rakinic M.D.
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