Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immune responses in human infections with Brugia malayi: specific cellular unresponsiveness to filarial antigens.</title><author><name sortKey="Piessens, W F" sort="Piessens, W F" uniqKey="Piessens W" first="W F" last="Piessens">W F Piessens</name></author><author><name sortKey="Mcgreevy, P B" sort="Mcgreevy, P B" uniqKey="Mcgreevy P" first="P B" last="Mcgreevy">P B Mcgreevy</name></author><author><name sortKey="Piessens, P W" sort="Piessens, P W" uniqKey="Piessens P" first="P W" last="Piessens">P W Piessens</name></author><author><name sortKey="Mcgreevy, M" sort="Mcgreevy, M" uniqKey="Mcgreevy M" first="M" last="Mcgreevy">M. Mcgreevy</name></author><author><name sortKey="Koiman, I" sort="Koiman, I" uniqKey="Koiman I" first="I" last="Koiman">I. Koiman</name></author><author><name sortKey="Saroso, J S" sort="Saroso, J S" uniqKey="Saroso J" first="J S" last="Saroso">J S Saroso</name></author><author><name sortKey="Dennis, D T" sort="Dennis, D T" uniqKey="Dennis D" first="D T" last="Dennis">D T Dennis</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">7350196</idno><idno type="pmc">371352</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC371352</idno><idno type="RBID">PMC:371352</idno><date when="1980">1980</date><idno type="wicri:Area/Pmc/Corpus">001830</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001830</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Immune responses in human infections with Brugia malayi: specific cellular unresponsiveness to filarial antigens.</title><author><name sortKey="Piessens, W F" sort="Piessens, W F" uniqKey="Piessens W" first="W F" last="Piessens">W F Piessens</name></author><author><name sortKey="Mcgreevy, P B" sort="Mcgreevy, P B" uniqKey="Mcgreevy P" first="P B" last="Mcgreevy">P B Mcgreevy</name></author><author><name sortKey="Piessens, P W" sort="Piessens, P W" uniqKey="Piessens P" first="P W" last="Piessens">P W Piessens</name></author><author><name sortKey="Mcgreevy, M" sort="Mcgreevy, M" uniqKey="Mcgreevy M" first="M" last="Mcgreevy">M. Mcgreevy</name></author><author><name sortKey="Koiman, I" sort="Koiman, I" uniqKey="Koiman I" first="I" last="Koiman">I. Koiman</name></author><author><name sortKey="Saroso, J S" sort="Saroso, J S" uniqKey="Saroso J" first="J S" last="Saroso">J S Saroso</name></author><author><name sortKey="Dennis, D T" sort="Dennis, D T" uniqKey="Dennis D" first="D T" last="Dennis">D T Dennis</name></author></analytic><series><title level="j">Journal of Clinical Investigation</title><idno type="ISSN">0021-9738</idno><imprint><date when="1980">1980</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We evaluated the cellular immune competence of 101 subjects living in an area of South Kalimantan (Borneo) where Malayan filariasis is endemic. All patients with elephantiasis but none with other clinical stages of filariasis reacted with adult worm antigens. The majority of subjects without clinical or parasitological evidence of filariasis and approximately one-half of those with amicrofilaremic filariasis reacted with microfilarial antigens. In contrast, most patients with patent microfilaremia did not respond to microfilarial antigens. The in vitro reactivity of all patient categories to nonparasite antigens was similar to that of the distant control group. These results indicate that patent microfilaremia is associated with a state of specific cellular immune unresponsiveness and are consistent with the current hypothesis that the various clinical manifestations of filariasis result from different types of immune responses to distinct antigens associated with different developmental stages of filarial worms.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Clin Invest</journal-id><journal-title>Journal of Clinical Investigation</journal-title><issn pub-type="ppub">0021-9738</issn></journal-meta><article-meta><article-id pub-id-type="pmid">7350196</article-id><article-id pub-id-type="pmc">371352</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Immune responses in human infections with Brugia malayi: specific cellular unresponsiveness to filarial antigens.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Piessens</surname><given-names>W F</given-names></name></contrib><contrib contrib-type="author"><name><surname>McGreevy</surname><given-names>P B</given-names></name></contrib><contrib contrib-type="author"><name><surname>Piessens</surname><given-names>P W</given-names></name></contrib><contrib contrib-type="author"><name><surname>McGreevy</surname><given-names>M</given-names></name></contrib><contrib contrib-type="author"><name><surname>Koiman</surname><given-names>I</given-names></name></contrib><contrib contrib-type="author"><name><surname>Saroso</surname><given-names>J S</given-names></name></contrib><contrib contrib-type="author"><name><surname>Dennis</surname><given-names>D T</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>1</month><year>1980</year></pub-date><volume>65</volume><issue>1</issue><fpage>172</fpage><lpage>179</lpage><abstract><p>We evaluated the cellular immune competence of 101 subjects living in an area of South Kalimantan (Borneo) where Malayan filariasis is endemic. All patients with elephantiasis but none with other clinical stages of filariasis reacted with adult worm antigens. The majority of subjects without clinical or parasitological evidence of filariasis and approximately one-half of those with amicrofilaremic filariasis reacted with microfilarial antigens. In contrast, most patients with patent microfilaremia did not respond to microfilarial antigens. The in vitro reactivity of all patient categories to nonparasite antigens was similar to that of the distant control group. These results indicate that patent microfilaremia is associated with a state of specific cellular immune unresponsiveness and are consistent with the current hypothesis that the various clinical manifestations of filariasis result from different types of immune responses to distinct antigens associated with different developmental stages of filarial worms.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 0018308 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 0018308 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.31. |  |